CClinicalTrials.gg
CompletedNCT00150293Updated Mar 5, 2015

Evaluation of Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures.

A Phase 3 interventional study of Pregabalin in Seizure Disorder, Partial, sponsored by Pfizer. Completed at 84 sites in 10 countries. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2015-03-05.

Sponsored by Pfizer · Phase 3, Interventional, and Treatment

Phase
Phase 3
Study type
Interventional
Enrollment
337
Allocation
Non-randomized
Ages
18 Years and older
Sex
All
01

Study summary

To determine long-term safety and efficacy of pregabalin in patients with partial seizures.

02

Conditions studied

  • Seizure Disorder, Partial
03

In context

Seizures

881 studies on the registry are indexed under Seizures; 143 are open to participants now.

This study's enrollment of 337 is above the median of 64 across 610 interventional studies indexed under Seizures.

Browse Seizures studies →

Lead sponsor

Pfizer is the lead sponsor of 3,244 studies on the registry; 139 are open to participants now.

Of its 582 completed or terminated interventional studies of FDA-regulated products, 381 (65%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Must have met the inclusion criteria for preceding double-blind study
  • Have received double-blind study medication and wish to receive open-label pregabalin.

Exclusion criteria

Exclusion Criteria:

  • Cannot be pregnant or considering becoming pregnant during the course of the study.
  • Cannot be receiving any concomitant medication that could alter the effectiveness of the pregabalin response or affect seizure frequency.
05

Study design

Phase
Phase 3
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
337 participants

Interventions

  • DrugPregabalin
06

What researchers measure

Primary outcomes

  1. Safety Efficacy

07

Study locations

84 sites
  • Pfizer Investigational Site
    Deakin, Australian Capital Territory 2600, Australia
  • Pfizer Investigational Site
    Camperdown, New South Wales 2050, Australia
  • Pfizer Investigational Site
    Chastwood, New South Wales 2067, Australia
  • Pfizer Investigational Site
    Cairns, Queensland 4870, Australia
  • Pfizer Investigational Site
    Maroochydore, Queensland 4558, Australia
  • Pfizer Investigational Site
    Footscray, Victoria 3011, Australia
  • Pfizer Investigational Site
    Parkville, Victoria 3050, Australia
  • Pfizer Investigational Site
    Perth, Western Australia 6001, Australia
  • Pfizer Investigational Site
    Auenbruggerplatz 22, A-8035 GRAZ, Austria
  • Pfizer Investigational Site
    Graz, 8020, Austria
  • Pfizer Investigational Site
    Innsbruck, A6020, Austria
  • Pfizer Investigational Site
    Linz, 4020, Austria
  • Pfizer Investigational Site
    Wien, 1220, Austria
  • Pfizer Investigational Site
    Leuven, 3000, Belgium
  • Pfizer Investigational Site
    Calgary, Alberta T2N 2T9, Canada
  • Pfizer Investigational Site
    Edmonton, Alberta T5G 0B7, Canada
  • Pfizer Investigational Site
    Penticton, British Columbia V2A 4V8, Canada
  • Pfizer Investigational Site
    Vancouver, British Columbia V5Z 1M9, Canada
  • Pfizer Investigational Site
    Halifax, Nova Scotia B3H 3A7, Canada
  • Pfizer Investigational Site
    Barrie, Ontario L4M 4S5, Canada
  • Pfizer Investigational Site
    London, Ontario N6A 5A5, Canada
  • Pfizer Investigational Site
    Ottawa, Ontario K1L 8L6, Canada
  • Pfizer Investigational Site
    Toronto, Ontario M5T 2S8, Canada
  • Pfizer Investigational Site
    Windsor, Ontario N8X5A6, Canada
  • Pfizer Investigational Site
    Montreal, Quebec H1T 2M4, Canada
  • Pfizer Investigational Site
    Montreal, Quebec H2L 4M1, Canada
  • Pfizer Investigational Site
    Montreal, Quebec H3A 2B4, Canada
  • Pfizer Investigational Site
    Regina, Saskatchewan S4T 1A5, Canada
  • Pfizer Investigational Site
    Saskatoon, Saskatchewan S7N 0W8, Canada
  • Pfizer Investigational Site
    Quebec, G1J 1Z4, Canada
  • Pfizer Investigational Site
    Ulm, BW 89081, Germany
  • Pfizer Investigational Site
    Berlin, BE10362, Germany
  • Pfizer Investigational Site
    Bernau, 16321, Germany
  • Pfizer Investigational Site
    Bonn, 53127, Germany
  • Pfizer Investigational Site
    Dresden, 01307, Germany
  • Pfizer Investigational Site
    Erlangen, 91054, Germany
  • Pfizer Investigational Site
    Essen, 45147, Germany
  • Pfizer Investigational Site
    Frankfurt, HE 60528, Germany
  • Pfizer Investigational Site
    Freiburg, 79106, Germany
  • Pfizer Investigational Site
    Goettingen, D-37075, Germany
  • Pfizer Investigational Site
    Hamburg, D-22337, Germany
  • Pfizer Investigational Site
    Mainz, 55101, Germany
  • Pfizer Investigational Site
    Muenchen, 81377, Germany
  • Pfizer Investigational Site
    AE Breda, 4836, Netherlands
  • Pfizer Investigational Site
    Blaricum, 1261 AN, Netherlands
  • Pfizer Investigational Site
    Ve Heeze, 5591, Netherlands
  • Pfizer Investigational Site
    Bialystok, 15-276, Poland
  • Pfizer Investigational Site
    Bydgoszcz, 85-826, Poland
  • Pfizer Investigational Site
    Choroszcz, 16-070, Poland
  • Pfizer Investigational Site
    Gdansk, 80-211, Poland
  • Pfizer Investigational Site
    Gdansk, 82-803, Poland
  • Pfizer Investigational Site
    Grudziadz, 86-300, Poland
  • Pfizer Investigational Site
    Katowice, 46-645, Poland
  • Pfizer Investigational Site
    Krakow, 31-112, Poland
  • Pfizer Investigational Site
    Lublin, 20-718, Poland
  • Pfizer Investigational Site
    Mosina, 62-050, Poland
  • Pfizer Investigational Site
    Olsztyn, 10-561, Poland
  • Pfizer Investigational Site
    Plock, 09-402, Poland
  • Pfizer Investigational Site
    Poznan, 60-780, Poland
  • Pfizer Investigational Site
    Poznan, 61-285, Poland
  • Pfizer Investigational Site
    Torun, 87-100, Poland
  • Pfizer Investigational Site
    Warsaw, 00-909, Poland
  • Pfizer Investigational Site
    Warsaw, 02-957, Poland
  • Pfizer Investigational Site
    Warszawa, 00-909, Poland
  • Pfizer Investigational Site
    Warszawa, Poland
  • Pfizer Investigational Site
    Coimbra, 3000-075, Portugal
  • Pfizer Investigational Site
    Porto, 4099, Portugal
  • Pfizer Investigational Site
    Barcelona, 08036, Spain
  • Pfizer Investigational Site
    Girona, 17007, Spain
  • Pfizer Investigational Site
    Granada, 18013, Spain
  • Pfizer Investigational Site
    Madrid, 28034, Spain
  • Pfizer Investigational Site
    Madrid, 28040, Spain
  • Pfizer Investigational Site
    Malaga, 29010, Spain
  • Pfizer Investigational Site
    Zaragoza, 50009, Spain
  • Pfizer Investigational Site
    Middlesborough, N. York TS5 5AZ, United Kingdom
  • Pfizer Investigational Site
    Washington, Tyne & Wear NE38 9JZ, United Kingdom
  • Pfizer Investigational Site
    Blackpool, FY3 8BP, United Kingdom
  • Pfizer Investigational Site
    Dundee, DD1 9SY, United Kingdom
  • Pfizer Investigational Site
    Glasgow, G11 6NT, United Kingdom
  • Pfizer Investigational Site
    Leeds, LS9 7TF, United Kingdom
  • Pfizer Investigational Site
    London, E1 1BB, United Kingdom
  • Pfizer Investigational Site
    Northampton, NN1 5BD, United Kingdom
  • Pfizer Investigational Site
    Wolverhampton, WV10 0QP, United Kingdom
  • Pfizer Investigational Site
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 5, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00150293
Lead sponsor
Pfizer
First posted
Sep 8, 2005
Start date
Mar 2002
Completion
Nov 2005
Last update
Mar 5, 2015

Study contacts

Pfizer CT.gov Call Center
study director · Pfizer
View the source record on ClinicalTrials.gov ↗

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