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CompletedNCT00144885IMAGEUpdated Feb 12, 2009

IMAGE-Endocarditis: Resonance Magnetic Imaging at the Acute Phase of Endocarditis

An interventional study of Modification of therapy in Endocarditis, Bacterial, sponsored by Assistance Publique - Hôpitaux de Paris. Completed at 1 site in France. Per ClinicalTrials.gov, last updated 2009-02-12.

Sponsored by Assistance Publique - Hôpitaux de Paris · Not applicable and Interventional

Phase
Not applicable
Study type
Interventional
Enrollment
150
Allocation
Non-randomized
Sex
All
01

Study summary

Patients with definite or possible infective endocarditis are included in this protocol, at the acute phase of the disease.

Read the detailed description

Patients with definite or possible infective endocarditis are included in this protocol, at the acute phase of the disease.

Resonance magnetic imaging (head and abdomen) will be performed systematically before Day 7.

The impact on the diagnosis and therapeutic options will be assessed, as compared to pre resonance magnetic nuclear (RMN) imaging declaration.

02

Conditions studied

  • Endocarditis, Bacterial

Keywords

  • Endocarditis
  • RMI
  • Impact measure
03

In context

Endocarditis, Bacterial

87 studies on the registry are indexed under Endocarditis, Bacterial; 19 are open to participants now.

This study's enrollment of 150 is above the median of 50 across 37 interventional studies indexed under Endocarditis, Bacterial.

Browse Endocarditis, Bacterial studies →

Lead sponsor

Assistance Publique - Hôpitaux de Paris is the lead sponsor of 3,578 studies on the registry; 1,030 are open to participants now.

Browse Assistance Publique - Hôpitaux de Paris studies →

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Acute phase of infective endocarditis

Exclusion criteria

Exclusion Criteria:

  • Contra indication to RMN
05

Study design

Phase
Not applicable
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
150 participants (actual)

Study arms

  • No intervention
    1

    Behavioral: Modification of therapy

Interventions

  • BehavioralModification of therapy

    Modification of the surgery date if adapted, modification of the antibiotics if adapted, based on RMI results

06

What researchers measure

Primary outcomes

  1. Modification of therapeutic project

    Time frame: As soon as RMI is performed

Secondary outcomes

  1. Modification of diagnostic classification (Duke modified criteria)

    Time frame: As soon as RMI is performed

07

Study locations

1 site
  • Hôpital Bichat Claude Bernard, 46 rue Henri Huchard
    Paris, 75877, France
08

References and documents

Publications

  • Mahr A, Batteux F, Tubiana S, Goulvestre C, Wolff M, Papo T, Vrtovsnik F, Klein I, Iung B, Duval X; IMAGE Study Group. Brief report: prevalence of antineutrophil cytoplasmic antibodies in infective endocarditis. Arthritis Rheumatol. 2014 Jun;66(6):1672-7. doi: 10.1002/art.38389. PubMed 24497495 ↗
  • Iung B, Tubiana S, Klein I, Messika-Zeitoun D, Brochet E, Lepage L, Al-Attar N, Ruimy R, Leport C, Wolff M, Duval X; ECHO-IMAGE Study Group. Determinants of cerebral lesions in endocarditis on systematic cerebral magnetic resonance imaging: a prospective study. Stroke. 2013 Nov;44(11):3056-62. doi: 10.1161/STROKEAHA.113.001470. Epub 2013 Sep 3. PubMed 24003046 ↗
  • Iung B, Klein I, Mourvillier B, Olivot JM, Detaint D, Longuet P, Ruimy R, Fourchy D, Laurichesse JJ, Laissy JP, Escoubet B, Duval X; Study Group. Respective effects of early cerebral and abdominal magnetic resonance imaging on clinical decisions in infective endocarditis. Eur Heart J Cardiovasc Imaging. 2012 Aug;13(8):703-10. doi: 10.1093/ehjci/jes023. Epub 2012 Feb 14. PubMed 22334638 ↗
  • Duval X, Iung B, Klein I, Brochet E, Thabut G, Arnoult F, Lepage L, Laissy JP, Wolff M, Leport C; IMAGE (Resonance Magnetic Imaging at the Acute Phase of Endocarditis) Study Group. Effect of early cerebral magnetic resonance imaging on clinical decisions in infective endocarditis: a prospective study. Ann Intern Med. 2010 Apr 20;152(8):497-504, W175. doi: 10.7326/0003-4819-152-8-201004200-00006. PubMed 20404380 ↗
09

Timeline

Tracking since Sep 25, 2026
Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Jun 2005, a primary completion of Dec 2008 and a completion of Dec 2008. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 2, 2005
First posted
Sep 5, 2005
Start
Jun 2005
Primary completionActual
Dec 2008
CompletionActual
Dec 2008
Last update
Feb 12, 2009
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Feb 12, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT00144885
Lead sponsor
Assistance Publique - Hôpitaux de Paris
First posted
Sep 5, 2005
Start date
Jun 2005
Primary completion
Dec 2008
Completion
Dec 2008
Last update
Feb 12, 2009

Study contacts

Xavier Duval
principal investigator · Hôpital Bichat, Assistance Publique Hôpitaux de Paris

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2005. You cannot join it, but the record below documents what was studied.

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Discussion

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