ClinicalTrials.gg
CompletedNCT00018733Updated Jan 21, 2009

Biological Aspects of Depression and Antidepressant Drugs

An interventional study of paroxetine and Desipramine in Depression, sponsored by US Department of Veterans Affairs. Completed at 1 site in United States. Open to participants aged 21 Years to 69 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2009-01-21.

Sponsored by US Department of Veterans Affairs · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Allocation
Randomized
Ages
21 Years to 69 Years
Sex
All
01

Study summary

This study will be measuring changes in depressive symptoms over a 7 week time period. Double-blind placebo controlled trial using the pharmacologic agents Paroxetine or Desipramine.

02

Conditions studied

  • Depression

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Keywords

  • Depression
03

In context

Depression

8,240 studies on the registry are indexed under Depression; 1,641 are open to participants now.

Browse Depression studies →

Lead sponsor

US Department of Veterans Affairs is the lead sponsor of 675 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
21 Years to 69 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Eligibility criteria

  • Diagnosis of major depressive disorder Ham-D Score > 18
  • English speaking with ability to read and sign an informed consent
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Masking
Double

Interventions

06

Study locations

1 site
  • South Texas Veterans Health Care System
    San Antonio, Texas 78229, United States
07

Timeline

Tracking since Sep 25, 2026
Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Sep 1996 and a completion of Dec 2001. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered
Jul 3, 2001
First posted
Jul 5, 2001
Start
Sep 1996
Completion
Dec 2001
Last update
Jan 21, 2009
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
No changes since tracking began. The registry record was last updated on Jan 21, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT00018733
First posted
Jul 5, 2001
Start date
Sep 1996
Completion
Dec 2001
Last update
Jan 21, 2009

Study contacts

Steve Brannan, M.D.
Cheryl Gonzalez, M.D.
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2004. You cannot join it, but the record below documents what was studied.

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Discussion

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