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CompletedNCT00001981Updated Nov 27, 2020

The Treatment and Natural History of Acromegaly

An observational study in Acromegaly and Pituitary Neoplasm, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-11-27.

Sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
117
Ages
18 Years and older
Sex
All
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Study summary

The purpose of this study is to investigate the treatment and natural history of acromegaly. We have a longstanding interest in acromegaly treatment, and a cohort that has been followed for 30 years, or more in some cases. We will continue to follow patients and recruit new patients for treatment and follow-up. Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to acromegaly.

Read the detailed description

The purpose of this study is to investigate the treatment and natural history of acromegaly. We have a longstanding interest in acromegaly treatment, and a cohort that has been followed for 30 years, or more in some cases. We will continue to follow patients and recruit new patients for treatment and follow-up.

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Conditions studied

  • Acromegaly
  • Pituitary Neoplasm

Keywords

  • Acromegaly
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In context

Pituitary Neoplasms

175 studies on the registry are indexed under Pituitary Neoplasms; 48 are open to participants now.

This study's enrollment of 117 is below the median of 150 across 71 observational studies indexed under Pituitary Neoplasms.

Browse Pituitary Neoplasms studies →

Lead sponsor

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is the lead sponsor of 529 studies on the registry; 54 are open to participants now.

Of its 79 completed or terminated interventional studies of FDA-regulated products, 50 (63%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The study involved patients who were referred to us and had acromegaly.@@@@@@

Eligibility criteria

  • INCLUSION CRITERIA:

Patients will be enrolled who are 18 years of age or over who are referred for care.

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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
117 participants (actual)

Groups and cohorts

  • Patients with acromegaly

    Patients with acromegaly

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What researchers measure

Primary outcomes

  1. resolution of IGF-1 Growth Hormone abnormality

    resolution of IGF-1 abnormality

    Time frame: every 6 months & at end of study

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Study locations

1 site
  • National Institutes of Health Clinical Center, 9000 Rockville Pike
    Bethesda, Maryland 20892, United States
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References and documents

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 27, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00001981
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Responsible party
Sponsor
First posted
Jan 24, 2000
Start date
Oct 2, 1991
Primary completion
Nov 20, 2020
Completion
Nov 20, 2020
Last update
Nov 27, 2020

Study contacts

Phillip Gorden, M.D.
principal investigator · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2020. You cannot join it, but the record below documents what was studied.

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