The Netherlands Cancer Institute: all 230 studies

Page 1 of 3. Open to participants first (66), then studies with results posted, then the rest; newest registration first within each.

• RADICAL-IO: thRee Cycles of immunotherApy Without raDical Therapy In mediCALly InOperable Stage I Non-small Cell Lung CancerNot yet recruitingNCT07808138Phase 2
• DiEtary Mimicry by Glucocorticoid Modulation Evaluation in ER+ Metastatic Breast Cancer Treatment: Efficacy and Response (DEMETER Trial)Not yet recruitingNCT07786051Phase 2
• Enfortumab Vedotin + Pembrolizumab Induction to Spare the Bladder in MIBCNot yet recruitingNCT07663747Phase 2
• Long-term Survivorship Challenges of Advanced/Metastatic GIST Patients Responding to Tyrosine Kinase Inhibitor Treatment: an Observational StudyRecruitingNCT07522762
• Novel Ga68-PSMA PET/CT-tracer to Differentiate Between Radiation Necrosis and Tumor Progression in Brain MetastasesRecruitingNCT07511933Not applicable
• Pembrolizumab Adjuvant in Patients With Early-stage Triple Negative Breast Cancer With Residual Disease After Neoadjuvant Pembrolizumab Plus ChemotherapyNot yet recruitingNCT07486687Phase 3
• The PROOV Study: Exploiting the Synergistic Effect of PARP Inhibition With Cisplatin and Hyperthermia During Interval Cytoreductive Surgery and HIPEC in Ovarian CancerRecruitingNCT07460180Phase 1/2
• Whole Body HER2 Quantification With 89Zr-Trastuzumab PET/CT to Asses Zr-trastuzumab Accumulation in HER2-mutated and HER2-overexpressing Metastatic Non-small Cell Lung CancerRecruitingNCT07436858Phase 1
• Dose De-escalation in Prostate Radiotherapy Using an MR-Linac in Two FractionsRecruitingNCT07391982Not applicable
• Contrast-enhanced Ultrasound for Sentinel Node DetectionRecruitingNCT07310758Phase 2/3
• Transtympanic STS Against Cisplatin-induced SNHL: the SOUND TrialRecruitingNCT07281508Phase 3
• Short Course of Radiotherapy Prior to Surgery of Soft Tissue SarcomasRecruitingNCT07071727Not applicable
• Functional Liver After SBRTRecruitingNCT07033364
• TAO-Towards Optimal (Neo)Adjuvant Systemic Therapy of Stage III Triple-negative Breast CancerRecruitingNCT06931769
• Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain MetastasesRecruitingNCT06888817Phase 3
• PEnile ReHABilitation After Nerve Sparing Robot-assisted Radical Prostatectomy for Prostate Cancer 2.0 (PEHAB-II)RecruitingNCT06875258Phase 4
• Induction Treatment for Initially Unresectable Colorectal Liver Metastases: Combined Hepatic Arterial Infusion Pump Therapy With Systemic TherapyRecruitingNCT06857773Phase 3
• Absorbed Tumor Dose in Peptide Receptor Radionuclide Therapy with Long-acting Somatostatin Analogues - ATSA TrialRecruitingNCT06855095Phase 2/3
• Towards Cure Via Only Ultra-short ICB in CSCCRecruitingNCT06823479Phase 2
• Feasibility of CBCT-Guided Online Adaptive Radiotherapy (FASCINATE)RecruitingNCT06691776Not applicable
• The Radium-select StudyRecruitingNCT06659926Not applicable
• The Diagnostic Value of FAPI PET/CT in Staging of Newly Diagnosed Prostate CancerNot yet recruitingNCT06634173Not applicable
• Earlier Detection and Optimization of Treatment and Prognosis for Patients With Early-onset Colorectal CancerRecruitingNCT06568679
• Feasibility of Primer Shot Radiotherapy for Non-small Cell Lung Cancer - PRIMERRecruitingNCT06528743Not applicable
• OPTImaL:Optimisation of Treatment for Patients With Low Stage Triple-negative Breast Cancer With High Stromal Tumor-infiltrating LymphocytesRecruitingNCT06476119
• Preoperative Accelerated Partial Breast Irradiation in Patients With Locally Recurrent or Second Primary Breast CancerRecruitingNCT06362616Not applicable
• Carboplatin/Paclitaxel + Pembrolizumab for Locoregionally Advanced Penile CancerRecruitingNCT06353906Phase 2
• NOvel Immunotherapy Strategies for Advanced Triple Negative Breast Cancer (TNBC) Patients: TONIC-3 TrialRecruitingNCT06342037Phase 2
• Distributed Learning of Edic and CardIac Dose Effects in Lung CancerNot yet recruitingNCT06329648
• Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology CombinationsRecruitingNCT06279130Phase 2/3
• Chemosensitivity During Phases of the Menstrual Cycle in Breast Cancer PatientsRecruitingNCT06273800Not applicable
• Intradermal Ipilimumab and Nivolumab in High Risk Stage II MelanomaRecruitingNCT06240143Phase 1/2
• Whole Body HER3 Quantification With Radiolabelled Patritumab Deruxtecan (HER3-DXd) PET/CTRecruitingNCT06222489Phase 2
• Peri-operative Slow-paced Breathing to Reduce Anxiety in Breast Cancer Surgery PatientsRecruitingNCT06192225Not applicable
• Neoadjuvant Trastuzumab, Pertuzumab and Tucatinib Without Chemotherapy in HER2-positive Breast Cancer: the TRAIN-4 StudyRecruitingNCT06162559Phase 1
• Radioembolisation and Chemotherapy in Liver Metastatic Breast Cancer PatientsRecruitingNCT06142344Not applicable
• Image-guided Navigation During Robotic Sentinel Node RemovalRecruitingNCT06091072Not applicable
• LB-100 (PP2A Inhibitor) and Atezolizumab (PD-L1 Inhibitor) in Metastatic Colorectal Cancer PatientsRecruitingNCT06012734Phase 1
• Basket Study for Oligo-metastatic Breast CancerRecruitingNCT05982678Phase 2
• Subtherapeutic Dose of Piracetam as a Therapy Adherence MarkerNot yet recruitingNCT05918341Phase 4
• Primary Chemoradiation VS. Neoadjuvant Chemotherapy Followed By Surgery As Treatment Strategy For LAVCRecruitingNCT05905315Phase 2
• 'Cancer Patients Better Life Experience'RecruitingNCT05827289Not applicable
• Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local ExcisionRecruitingNCT05772923Not applicable
• Tracer-Guided Surgery for Recurrent Prostate CancerRecruitingNCT05555017Phase 2
• EffectiveNess of a Multimodal preHAbilitation Program in patieNts With Bladder canCEr Undergoing CystectomyRecruitingNCT05480735Not applicable
• DESCARTES: De-ESCAlation of RadioTherapy in Patients With Pathologic Complete rESponse to Neoadjuvant Systemic TherapyRecruitingNCT05416164Not applicable
• Association of Silicone Breast Implants With Overall Wellbeingand Auto-immune DiseasesEnrolling by invitationNCT05400954
• COntinue the SaMe Systemic Therapy After Local Ablative Therapy for Oligo Progression in Metastatic Breast Cancer - the COSMO StudyRecruitingNCT05301881Phase 2
• FMT to Convert Response to ImmunotherapyRecruitingNCT05251389Phase 1/2
• FAPI PET/CT for Lymph Node Staging in Colorectal CarcinomaRecruitingNCT05209750Not applicable
• The Prognostic Role of Lymph Node Dissection In Men With Prostate Cancer Treated With Radical ProstatectomyRecruitingNCT05109910Not applicable
• Osimertinib Resistance in Patients With Non-small-cell Lung Carcinoma That Have Progressed.RecruitingNCT04737382Not applicable
• International Prospective Registry on Local Treatment Approaches in MLSRecruitingNCT04699292
• The Prospective Observational COMPRAYA Cohort StudyRecruitingNCT04682470
• The MR-Linac Technical Feasibility ProtocolRecruitingNCT04351204Not applicable
• Avoiding Sentinel Lymph Node Biopsy in Breast Cancer Patients After Neoadjuvant ChemotherapyNot yet recruitingNCT04225858Not applicable
• Treatment of Locally Advanced VULvar CArcinoma in a Neoadjuvant Setting With Carboplatin and Paclitaxel Chemotherapy (VULCANize)RecruitingNCT04192253Phase 2
• Treatment of Metastatic Vulvar Carcinoma With Carboplatin and Paclitaxel ChemotherapyRecruitingNCT04161664Phase 2
• Immune Induction Strategies to Improve Response to Immune Checkpoint Blockade in Triple Negative Breast Cancer (TNBC) PatientsRecruitingNCT04159818Phase 2
• Blood Sampling of Healthy Volunteers for Immunological ResearchRecruitingNCT03819829Not applicable
• Pre-operative Trial for Breast Cancer With Nivolumab in Combination With Novel IORecruitingNCT03815890Phase 2
• Sentinel Lymph Node Procedure in Testicular Germ Cell TumourNot yet recruitingNCT03448822
• "Wait-and-see" Policy for Complete Responders After Chemoradiotherapy for Rectal CancerRecruitingNCT03426397
• Neoadjuvant Immune Checkpoint Inhibition and Novel IO Combinations in Early-stage Colon CancerRecruitingNCT03026140Phase 2
• The Drug Rediscovery Protocol (DRUP Trial)RecruitingNCT02925234Phase 2
• A Platform of Patient Derived Xenografts (PDX) and 2D/3D Cell Cultures of Soft Tissue Sarcomas (STS)RecruitingNCT02910895Not applicable
• Navigated Partial NephrectomyCompletedNCT07315100Not applicable
• Cardiotoxicity and Other Late Effects After Radiotherapy and Immuno-chemoTherapy in Non-Hodgkin lYmphomaCompletedNCT07041827
• Validation of ICG-99mTc-nanoscan as Hybrid Tracer for Sentinel Node BiopsyCompletedNCT06666634Not applicable
• A Pilot Study of Dose dE-eScalaTion IN prostATe radIOtherapy usiNg the MRLCompletedNCT06284304Not applicable
• Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without RelatlimabActive, not recruitingNCT06237920Phase 2
• Navigated Abdominal Lymph Node DissectionsCompletedNCT05867095Not applicable
• The Food-effect on Alectinib PharmacokineticsCompletedNCT05710133Not applicable
• Standard Moderately Hypofractionated RT vs. Ultra-hypofractionated Focal Lesion Ablative Microboost in Prostate CancerActive, not recruitingNCT05705921Not applicable
• Galunisertib Combined With Capecitabine in Advanced CRC With PMActive, not recruitingNCT05700656Phase 1/2
• Effect of a Bundle of Non-pharmacological Interventions on the Stress Response to SurgeryStatus unknownNCT05638152
• Tracked Ultrasound for Patient Registration in Surgical Navigation During Abdominal Cancer SurgeryCompletedNCT05637359
• Vessel- and Bone-based Ultrasound RegistrationCompletedNCT05637346Not applicable
• Upfront Resection of Locally Advanced NSCLC Followed by ChemoradiotherapyStatus unknownNCT05620199Not applicable
• Ultrasound-guided Erector Spinae Plane Block Versus Paravertebral Block in Breast Cancer Patients Undergoing Mastectomy With Immediate Reconstruction - a Non-inferiority TrialStatus unknownNCT05590559Not applicable
• CYP3A4 Activity in Patients With Prostate Cancer Versus Male Patients With Other Solid TumoursCompletedNCT05518799Not applicable
• Body Surface Area-based vs Concentration-based Dosing of Cisplatin for Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Women With Advanced Ovarian CancerActive, not recruitingNCT05406674Phase 2
• Anti-PD-1 Re-challenge After Immune Priming by Ipilimumab and Immune Boosting by Radiotherapy in Advanced NSCLCActive, not recruitingNCT05401786Phase 2
• Health-related Quality of Life and Late Effects Among SURVivors of Cancer in Adolescence and Young Adulthood: The SURVAYA StudyCompletedNCT05379387
• Prospective Clinical Validation of a Novel Multitarget FIT in CRC ScreeningStatus unknownNCT05314309
• Checkpoint Inhibition and Chemoradiotherapy as Bladder Sparing Treatment in UCActive, not recruitingNCT05200988Phase 2
• EBRT + Lu-PSMA for N1M0 Prostate CancerCompletedNCT05162573Phase 1
• Improved Implant for Reconstruction Purposes After Mandibular ResectionTerminatedNCT05153733Not applicable
• Neoadjuvant Study With Combination Immuno-oncology for Primary Clear Cell Renal Cell CancerActive, not recruitingNCT05148546Phase 2
• Pembrolizumab for Locally Advanced, Irresectable, Non-metastatic dMMR Colorectal CancersActive, not recruitingNCT05131919Phase 2
• Multispectral Fluorescence as a Tool to Separate Healthy and Disease Related Lymphatic Anatomies in Prostate Cancer.CompletedNCT05120973
• Sarcomas and DDR-Inhibition; a Combined Modality StudyTerminatedNCT05116254Phase 1
• Liquid Biopsies for Improving the Pre-operative Diagnosis of Ovarian CancerStatus unknownNCT04971421
• Neoadjuvant Ipilimumab Plus Nivolumab Versus Standard Adjuvant Nivolumab in Macroscopic Stage III MelanomaActive, not recruitingNCT04949113Phase 3
• Combination Therapy of RMC-4630 and LY3214996 in Metastatic KRAS Mutant CancersTerminatedNCT04916236Phase 1
• Pre-operative Immunotherapy in Stage II-III Urothelial CancerCompletedNCT04871594Phase 1
• Cetuxibab to Reduce Circulating Tumor Cells in Early Stage NSCLCWithdrawnNCT04648189Phase 2
• Neo-adjuvant Nivolumab or Nivolumab With Ipilimumab in Advanced Cutaneous Squamous Cell Carcinoma Prior to SurgeryCompletedNCT04620200Phase 2
• INtra-operative Evaluation of a Novel FLUorescENt C-mEt Tracer in Penile and TongueCompletedNCT04574427
• Hepatic Arterial Infusion Pump Chemotherapy Combined With Systemic Chemotherapy (PUMP-IT)Status unknownNCT04552093Phase 2/3

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