St. Jude Children's Research Hospital: Leukemia trials

The registry lists 53 Leukemia studies with St. Jude Children's Research Hospital as lead sponsor. 1 are open to participants now and 21 have results posted.

Phase 1 14Phase 2 15Phase 3 11No phase 16(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Prospective Trial of Dalbavancin-Based Prophylaxis in Children and Adolescents With High-Risk LeukemiaRecruitingNCT06810583Phase 1
• Mindfulness Interventions to Improve Health Activation, Coping, and Stress Among Childhood Cancer SurvivorsActive, not recruitingNCT06053268Not applicableResults posted
• Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic LeukemiaActive, not recruitingNCT03573700Phase 1/2Results posted
• Selinexor in Combination With Fludarabine and Cytarabine in Patients With Refractory or Relapsed Acute Myeloid LeukemiaTerminatedNCT03071276Phase 2Results posted
• Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or LymphomaTerminatedNCT02518750Phase 2Results posted
• Yoga to Alleviate Fatigue, Anxiety and Pain in Adolescents During Treatment for Lymphoma or LeukemiaTerminatedNCT02473523Not applicableResults posted
• Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic MalignanciesTerminatedNCT02419755Phase 2Results posted
• Treatment for Executive Dysfunction in Adult Survivors of Childhood Acute Lymphoblastic LeukemiaCompletedNCT02336282Not applicableResults posted
• Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior TransplantationTerminatedNCT02259348Phase 2Results posted
• Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and LymphomaCompletedNCT01700946Phase 2Results posted
• T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic TransplantTerminatedNCT01621477Phase 2Results posted
• Mature B-Cell Lymphoma And Leukemia Study IIIActive, not recruitingNCT01046825Phase 2/3Results posted
• The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot DropTerminatedNCT01001390Not applicableResults posted
• Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And A Study Of NK Cell Transplantation In Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT00703820Phase 3Results posted
• Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological MalignanciesCompletedNCT00566696Phase 2Results posted
• Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic LeukemiaCompletedNCT00549848Phase 3Results posted
• Natural Killer (NK) Cell Transplantation for AMLCompletedNCT00187096Not applicableResults posted
• A Severity-Adapted Clinical Trial of Diminished Bone Mineral Density in Acute Lymphoblastic Leukemia SurvivorsCompletedNCT00186901Phase 3Results posted
• Therapy for Pediatric Relapsed or Refractory Acute Lymphoblastic LeukemiaCompletedNCT00186875Phase 2Results posted
• HLA-Nonidentical Stem Cell and Natural Killer Cell Transplantation for Children Less the Two Years of Age With Hematologic MalignanciesCompletedNCT00145626Phase 2Results posted
• Therapy for Newly Diagnosed Patients With Acute Lymphoblastic LeukemiaCompletedNCT00137111Phase 3Results posted
• Treatment of Patients With Newly Diagnosed Acute Myeloid Leukemia or MyelodysplasiaCompletedNCT00136084Phase 3Results posted
• Continuous Ambulatory Monitoring to Predict Elevated Risk of Infection in Children With Lymphoblastic Leukemia Undergoing Induction Chemotherapy (CAMPER-ALL)WithdrawnNCT04322084
• Transcranial Direct Current Stimulation of the Temporal Cortex in Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)Active, not recruitingNCT04105530Not applicable
• Postural Control Under Different Cognitive Loads in Adult Survivors of Acute Lymphoblastic Leukemia and Age-Matched Healthy IndividualsCompletedNCT03581045
• Treatment With Combination Chemotherapy for Relapsed or Refractory Acute Lymphoblastic LeukemiaTerminatedNCT03515200Phase 1
• Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous LineageCompletedNCT03194932Phase 1
• Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and LymphomaActive, not recruitingNCT03117751Phase 2/3
• Genetic Study of Familial Acute Lymphoblastic LeukemiaCompletedNCT03067584
• Neurocognitive and Psychosocial Outcomes in Survivors of Childhood Leukemia With Down SyndromeCompletedNCT02859389
• Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic SyndromeTerminatedNCT02676323Phase 1
• Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic SyndromeCompletedNCT02212561Phase 1
• Transfusional Iron Overload Among Leukemia SurvivorsCompletedNCT01965171
• A Pediatric Study of a Plerixafor Containing Regimen In Second Allogeneic Stem Cell TransplantationCompletedNCT01068301Phase 1
• Motor Proficiency And Physical Activity in Adult Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)CompletedNCT01047020
• Risk of Psychopathology and Neurocognitive Impairment in Leukemia SurvivorsCompletedNCT01014195
• Genetically Modified Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic LeukemiaCompletedNCT00995137Phase 1
• Sorafenib in Combination With Cytarabine and Clofarabine in Patients With Refractory or Relapsed Hematologic MalignanciesCompletedNCT00908167Phase 1
• Physical Activity to Modify Sequelae and Quality of Life in Childhood Acute Lymphoblastic LeukemiaCompletedNCT00902213Not applicable
• Aerobic and Strengthening Exercise for Acute LeukemiaCompletedNCT00766311Not applicable
• Pilot Study of Haploidentical Natural Killer Cell Infusions for Poor Prognosis Non-AML Hematologic MalignanciesCompletedNCT00697671Phase 1
• Compassionate Use of Erwinase For Pediatric Patients With Acute Lymphoblastic Leukemia Or Non Hodgkins LymphomaCompletedNCT00693602Phase 1
• Autologous Bone Marrow Transplant for Children With Acute Myelogenous Leukemia (AML) in First Complete RemissionCompletedNCT00667927Phase 1
• Phase I Study of Bevacizumab and Sorafenib Combined With Low Dose Cyclophosphamide in Patients With Refractory Solid Tumors and LeukemiaCompletedNCT00665990Phase 1
• Neurologic Morbidity and Disability in Acute Lymphoblastic Leukemia SurvivorsCompletedNCT00664131
• Pilot Study of Expanded, Donor Natural Killer Cell Infusions for Refractory Non-B Lineage Hematologic Malignancies and Solid TumorsCompletedNCT00640796Phase 1
• Treatment of Burkitt Lymphoma/Leukemia and B Large Cell NHLCompletedNCT00187161Phase 2
• A Study of Children With Refractory or Relapsed ALLCompletedNCT00187083Phase 3
• Total Therapy Study XIV for Newly Diagnosed Patients With Acute Lymphoblastic LeukemiaTerminatedNCT00187005Phase 3
• Haploidentical Stem Cell Transplantation for Patients With Hematologic MalignanciesCompletedNCT00186823Phase 3
• Stem Cell Transplantation for Patients With Hematologic MalignanciesCompletedNCT00152139Phase 3
• Haploidentical Stem Cell Transplant for Treatment Refractory Hematological MalignanciesCompletedNCT00145613Phase 2
• Stem Cell Transplantation as Immunotherapy for Hematologic MalignanciesCompletedNCT00143559Phase 2