National Institutes of Health: Severe Combined Immunodeficiency trials
The registry lists 13 Severe Combined Immunodeficiency studies with National Institutes of Health as lead sponsor. 3 are open to participants now and 1 have results posted.
Phase 1 5Phase 2 4No phase 7(a study in two phases counts in both)
Studies
Open to participants first, then studies with results posted, then the rest; newest registration first within each.
- Natural History Study of SCID DisordersEnrolling by invitationNCT01186913
- Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation DisordersEnrolling by invitationNCT00895271
- Genetic Basis of ImmunodeficiencyRecruitingNCT00055172
- Treatment for Growth Failure in Patients With X-Linked Severe Combined Immunodeficiency: Phase 2 Study of Insulin-Like Growth Factor-1TerminatedNCT00490100Phase 1/2Results posted
- Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and SirolimusWithdrawnNCT04370795Phase 1/2
- Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age With X-Linked Severe Combined ImmunodeficiencyStatus unknownNCT03315078Phase 1/2
- Patients Treated for SCID (1968-Present)Status unknownNCT01346150
- Quality of Life and Neuropsychiatric Sequelae in Patients Treated With Gene Therapy for ADA-SCID and in Their ParentsWithdrawnNCT01182857
- Stem Cell Gene Therapy to Treat X-Linked Severe Combined Immunodeficiency (XSCID)CompletedNCT00028236Phase 1
- Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) DeficiencyCompletedNCT00018018Phase 1
- Influences on Female Adolescents' Decisions Regarding Testing for Carrier Status of XSCIDCompletedNCT00006335
- Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History StudyCompletedNCT00001255
- Cord Blood Stem Cell Transplantation Study (COBLT)CompletedNCT00000603Phase 2