National Institute of Mental Health (NIMH): all 367 studies

Page 1 of 4. Open to participants first (45), then studies with results posted, then the rest; newest registration first within each.

• A Longitudinal Natural History Study of Immune Biomarkers in Neuropsychiatric IllnessRecruitingNCT07877246
• First-in-Human Evaluation of [11C]JMJ-129-d2 for PDE4D Imaging in Healthy VolunteersRecruitingNCT07853781Phase 1
• Ecological Momentary Assessment of State-Dependent Decision-Making and Metacognition Across a Psychopathology ContinuumNot yet recruitingNCT07801079
• Augmenting Parent Management Training for Child Temper Outbursts Using a Digital ToolRecruitingNCT07764536
• PET Imaging of Noradrenergic Transmission in the BrainRecruitingNCT07686393Phase 1
• Psychotherapy for Irritability in Youth: Comparing Active Treatment to Nonactive Psychoeducation Supportive PsychotherapyRecruitingNCT07640802
• Evaluation of [11C]ZTP-1 to Image PDE4BRecruitingNCT07625345Phase 1
• Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD)RecruitingNCT07566468
• PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)RecruitingNCT07169630Phase 1
• Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)RecruitingNCT07027839Phase 1
• PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)RecruitingNCT06920628Phase 1
• Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy VolunteersRecruitingNCT06874205Phase 1
• PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use DisorderRecruitingNCT06795581Phase 1
• Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric AnxietyRecruitingNCT06595953Phase 2
• Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant DepressionRecruitingNCT06511908Phase 2
• Study Brain Mechanisms of Frustration With Magnetoencephalography in Healthy VolunteersRecruitingNCT06484088Early Phase 1
• Natural History of Depression, Bipolar Disorder and Suicide RiskRecruitingNCT06462196
• [18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PETRecruitingNCT05703685Phase 1
• NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar DisorderRecruitingNCT05669703
• State-dependent Interoception, Value-based Decision-making, and IntrospectionRecruitingNCT05666726Not applicable
• Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II TrialRecruitingNCT05608434Phase 1/2
• Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) ArrayRecruitingNCT04950309Not applicable
• Long-term Observation of Participants With Mood DisordersRecruitingNCT04877977
• Role of GABAergic Transmission in Auditory Processing in Autism Spectrum DisorderRecruitingNCT04798274Not applicable
• Developing Brain, Impulsivity and CompulsivityRecruitingNCT04631042
• PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)RecruitingNCT04582916Phase 1
• PET Imaging of Cyclooxygenases in Neurodegenerative Brain DiseaseRecruitingNCT04396873Phase 1
• Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major DepressionRecruitingNCT03973268Phase 1
• Characterization and Treatment of Adolescent DepressionRecruitingNCT03388606
• Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural StudiesRecruitingNCT03304665
• Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive DisorderRecruitingNCT03065335Phase 1
• Neurobiology of SuicideRecruitingNCT02543983Phase 2
• Psychological Treatments for Youth With Severe Irritability.RecruitingNCT02531893
• Brain Stimulation and Vision TestingRecruitingNCT01617408
• A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying PubertyRecruitingNCT01434368
• Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and MuscleRecruitingNCT01266577Not applicable
• Defining the Brain Phenotype of Children With Williams SyndromeRecruitingNCT01132885
• Top-Down Attentional Control of Visual-ProcessingRecruitingNCT01087281
• Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety DisordersRecruitingNCT00397111
• The Neurodevelopmental and Behavioral Phenotyping Screening ProtocolRecruitingNCT00271622
• MRS Measurement of Glutamate and GABA Metabolism in BrainRecruitingNCT00109174Not applicable
• Studies of Brain Function and Course of Illness in Pediatric Bipolar DisorderRecruitingNCT00025935
• Evaluation of Patients With Mood and Anxiety Disorders and Healthy VolunteersRecruitingNCT00024635
• Study of Neuro-Cognitive Correlates of Pediatric Anxiety DisordersRecruitingNCT00018057Phase 2
• Studies of Blood Flow to the Brain During ThoughtRecruitingNCT00001360
• [18F]SF12051 for Imaging the 18-kDa Translocator Protein (TSPO) in Brain and Whole Body of Healthy SubjectsTerminatedNCT05564429Phase 1Results posted
• [11C]-(R)-Rolipram to Measure cAMP Signaling Before and After KetamineTerminatedNCT05522673Phase 1Results posted
• Identifying Decision Making Parameters in Healthy Volunteers and Anxiety PatientsCompletedNCT05092971Not applicableResults posted
• PET Imaging of Cyclooxygenase in Multiple SclerosisTerminatedNCT05062083Phase 2Results posted
• Antidepressant Effects of TS-161 in Treatment-Resistant DepressionTerminatedNCT04821271Phase 2Results posted
• Phase 1 Evaluation of (2R,6R)-HydroxynorketamineCompletedNCT04711005Phase 1Results posted
• PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) RadioligandTerminatedNCT03958630Phase 1Results posted
• Novel PET Radioligand as an Inflammatory Biomarker in Musculoskeletal ConditionsTerminatedNCT03912428Phase 1Results posted
• Title: Evaluation of a Novel PET Radioligand for Phosphodiesterase-4D (PDE4D)CompletedNCT03861000Phase 1/2Results posted
• Estrogen Receptor Beta and MoodCompletedNCT03689543Phase 2Results posted
• Effect of Transcranial Magnetic Stimulation to the Frontoparietal Attention Network on Anxiety Potentiated StartleCompletedNCT03027414Not applicableResults posted
• PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright SyndromeCompletedNCT02743377Phase 1/2Results posted
• Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive DisorderCompletedNCT02484456Phase 2Results posted
• Cognitive vs. Emotional Psychopharmacological Manipulations of Fear vs. AnxietyCompletedNCT02153944Phase 4Results posted
• Does Enhanced Glutamate Transporter Function Produce Antidepressant Effects in People With Major Depression?TerminatedNCT02049385Phase 1/2Results posted
• A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With AutismTerminatedNCT01887132Phase 2Results posted
• Translocator Protein and Inflammation After Traumatic Brain InjuryCompletedNCT01547780Phase 1/2Results posted
• Intravenous Immunoglobulin for PANDASCompletedNCT01281969Phase 3Results posted
• The Use of Metformin in the Treatment of Antipsychotic-Induced Weight Gain in Schizophrenia (The METS Study)CompletedNCT00816907Phase 4Results posted
• Double-Blind Placebo-Controlled Trial of Riluzole in Pediatric Bipolar DisorderTerminatedNCT00805493Phase 2Results posted
• Comparison of Optimal Antipsychotic Treatments for Adults With SchizophreniaCompletedNCT00802100Phase 4Results posted
• A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood DysregulationCompletedNCT00794040Phase 2Results posted
• The Effect of Donepezil (Aricept(Registered Trademark)) on REM Sleep in Children With AutismCompletedNCT00695136Phase 1/2Results posted
• Effectiveness of Lithium Plus Optimized Medication in Treating People With Bipolar DisorderCompletedNCT00667745Phase 4Results posted
• Combining Medications to Enhance Depression OutcomesCompletedNCT00590863Phase 4Results posted
• The Effects of Atomoxetine on Cognition and Brain Function Based on Catechol-O-methyltransferase(COMT) GenotypeTerminatedNCT00548327Phase 2Results posted
• Antidepressant Effects of NR2B in Major DepressionCompletedNCT00472576Phase 1Results posted
• Comparison of Antipsychotics for Metabolic Problems in Schizophrenia or Schizoaffective DisorderCompletedNCT00423878Phase 4Results posted
• Minocycline to Treat Childhood Regressive AutismCompletedNCT00409747Phase 4Results posted
• The Antidepressant Efficacy of the Anticholinergic ScopolamineTerminatedNCT00369915Phase 2Results posted
• Riluzole to Treat Child and Adolescent Obsessive-Compulsive Disorder With or Without Autism Spectrum DisordersCompletedNCT00251303Phase 2Results posted
• Use of an Antibiotic as an Enhancer for the Treatment of Social PhobiaCompletedNCT00128401Phase 2Results posted
• Org 24448 to Treat Major DepressionTerminatedNCT00113022Phase 2Results posted
• Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral ContraceptivesTerminatedNCT00089414Phase 2Results posted
• Rapid Antidepressant Effects of Ketamine in Major DepressionCompletedNCT00088699Phase 1/2Results posted
• Lexapro and Pramipexole and to Treat Major DepressionCompletedNCT00086307Phase 2Results posted
• Rapid Antidepressant Effects of Yohimbine in Major DepressionCompletedNCT00078715Phase 2Results posted
• Clinical Trial of Estrogen for Postpartum DepressionTerminatedNCT00059228Phase 2Results posted
• Expectation of Unpleasant Events in Anxiety DisordersCompletedNCT00055224Not applicableResults posted
• Riluzole to Treat Depression in Bipolar DisorderTerminatedNCT00054704Phase 2Results posted
• Brain Imaging Changes in Fear and AnxietyCompletedNCT00047853Not applicableResults posted
• Clinical Trial of Tolcapone for Cognition in SchizophreniaTerminatedNCT00044083Phase 2Results posted
• Raloxifene and Rimostil for Perimenopause-Related DepressionCompletedNCT00030147Phase 4Results posted
• Effects of Arousal and Stress in AnxietyCompletedNCT00026559Not applicableResults posted
• Comparison of Clozapine vs Olanzapine in Childhood-Onset Psychotic DisordersCompletedNCT00001656Phase 4Results posted
• The Role of Hormones in Postpartum Mood DisordersCompletedNCT00001481Phase 2Results posted
• The Effects of Reproductive Hormones on Mood and BehaviorCompletedNCT00001322Phase 1/2Results posted
• A Treatment Study for Premenstrual Syndrome (PMS)CompletedNCT00001259Phase 1Results posted
• Phase II Study of the Efficacy of Peptide T in HIV-Positive Individuals With Cognitive Impairment.CompletedNCT00000392Phase 2Results posted
• Transcranial Magnetic Stimulation for Youth With Treatment-Resistant Major Depressive DisorderWithdrawnNCT05652465Phase 2
• Characterization and Brain Mechanisms of Frustration in Youth With Severe Irritability or Attention Deficit Hyperactivity Disorder (ADHD)WithdrawnNCT05357495Not applicable
• Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)Active, not recruitingNCT05172271Not applicable
• Emotional, Social, Cognitive and Behavioral Sequalae of the COVID-19 PandemicCompletedNCT04823988
• Mental Health Impact of the COVID-19 Pandemic on Amish and Mennonite Participants in AMBiGenCompletedNCT04684615
• Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric PopulationsActive, not recruitingNCT04639830

← National Institute of Mental Health (NIMH) overview and focus areas