Massachusetts General Hospital: Amyotrophic Lateral Sclerosis trials

The registry lists 20 Amyotrophic Lateral Sclerosis studies with Massachusetts General Hospital as lead sponsor. 3 are open to participants now and 8 have results posted.

Phase 1 2Phase 2 6Phase 3 2No phase 12(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Healey ALS MyMatch Common Screening ProtocolNot yet recruitingNCT07400393
• Resiliency Intervention for Patients With ALS and Their Care-PartnersNot yet recruitingNCT06968468Not applicable
• ALS/MND Natural History Study Data RepositoryRecruitingNCT05966038
• Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket TrialCompletedNCT05189106Phase 1/2Results posted
• Safety of Urate Elevation in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT03168711Phase 2Results posted
• Electronic-health Application To Measure Outcomes REmotely Clinical TrialCompletedNCT02418546Not applicableResults posted
• A Pilot Study of Inosine in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT02288091Phase 1Results posted
• Gilenya in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01786174Phase 2Results posted
• High Fat/High Calorie Trial in Amyotrophic Lateral SclerosisCompletedNCT00983983Phase 2Results posted
• Study to Investigate the Safety and Efficacy of Lithium in Volunteers With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT00818389Phase 2/3Results posted
• Clinical Trial Ceftriaxone in Subjects With ALSCompletedNCT00349622Phase 3Results posted
• Trial of Oral Digoxin in Individuals With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT07047209Phase 2
• Olfactory Deficits in Neurologic DiseaseCompletedNCT05019014
• The E-health Application To Modify ORal Energy Intake and Measure Outcomes REmotely in ALS Clinical Trial (EAT MORE2)CompletedNCT04051333
• Chromatic Pupillometry to Assess the Melanopsin-Light Pathway in Progressive Supranuclear PalsyStatus unknownNCT03330353
• Imaging and BioFluid Biomarkers in Amyotrophic Lateral SclerosisCompletedNCT02559869
• Longitudinal Study of Outcomes Measures in ALS TrialsCompletedNCT01911130
• A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) BiomarkersCompletedNCT01495390
• Validation of Biomarkers in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT00677768
• Validation of a New Device to Measure Neuromuscular Disease ProgressionCompletedNCT00606918