M.D. Anderson Cancer Center: Breast Neoplasms trials

The registry lists 201 Breast Neoplasms studies with M.D. Anderson Cancer Center as lead sponsor. 28 are open to participants now and 50 have results posted.

Early Phase 1 3Phase 1 41Phase 2 64Phase 3 12Phase 4 1No phase 93(a study in two phases counts in both)

Studies

Page 1 of 3. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Wearable Device Tracked Recovery From Autologous Breast Reconstructive SurgeryNot yet recruitingNCT07631026Not applicable
• Creating Opportunities For Personal Empowerment (COPE) In Women With Breast Cancer During First-Line Therapy: A Pilot Randomized Controlled TrialNot yet recruitingNCT07610499Not applicable
• Phase 1b Study Of TRICK-NK In Combination With T-Dxd In Treatment-Refractory Breast CancersNot yet recruitingNCT07553390Phase 1
• Group-based Comprehensive Lifestyle Program for Women With Metastatic Breast CancerRecruitingNCT07179809Not applicable
• Shortening Adjuvant Photon and Proton Irradiation (SAPPHIRe-II): A 4 Cohort, Randomized, Phase II Multi-center Trial Evaluating Shorter Schedules of Adjuvant Regional Nodal Irradiation Among Women and Men With Node-positive and High-risk Node-negative Invasive Breast CancerRecruitingNCT07076485Phase 2
• Multi-center MRD Registry for Inflammatory Breast CancerRecruitingNCT06966050
• EMERALD: Endocrine Therapy oMission With Radiation in ER+ Breast Cancer: Assessing Quality of Life and Disease Control: a Prospective Phase II TrialRecruitingNCT06897488Phase 2
• Social and Environmental Determinants of Breast Cancer Survivorship: the Black Breast Cancer Survivor's Intervention (BBCSI)RecruitingNCT06885203Not applicable
• Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)RecruitingNCT06545682Phase 1
• Surveillance MRI Registry for Patients Who Had Breast Cancer With Dense Breast TissueRecruitingNCT06127797
• Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Tissue Nanomechanical Phenotype EvaluationRecruitingNCT05774678Phase 3
• Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer SurgeryRecruitingNCT05766891Phase 2/3
• Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and TelegeneticsRecruitingNCT05694559Not applicable
• The C-MERIT Screening Cohort: Contrast-enhanced Mammography for Breast Cancer Screening and Risk Assessment in Women With Dense BreastsRecruitingNCT05667532Not applicable
• Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics.RecruitingNCT05649072Not applicable
• Temporal Immunologic Changes With Hypofractionated Radiation-Induced DNA Damage in Breast CancerRecruitingNCT05406232
• Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or ThoraxRecruitingNCT05092373Phase 1
• Neutrophil Extracellular Traps Formation in Breast Cancer Patients Taking TamoxifenRecruitingNCT05056857
• Comparison of Synthetic Mammography Versus Full-Field Digital Mammography in Image Interpretation and Performance MetricsRecruitingNCT05056818
• Comparative Performance of Molecular Breast Imaging (MBI) to Magnetic Resonance Imaging (MRI) of the Breast in Identifying and Excluding Breast Carcinoma in Women at High Risk for Breast CancerRecruitingNCT05042687Not applicable
• A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)RecruitingNCT05035836Phase 2
• Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast CancerRecruitingNCT04090567Phase 2
• Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer PatientsRecruitingNCT04038619Phase 1
• Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction SurgeryRecruitingNCT04003038Not applicable
• Serial Imaging of the Novel Radiotracer [^18F] FLuorthanatrace ([^18F] FTT) by PET/CTFRecruitingNCT03604315Phase 1
• Mammography, Early Detection Biomarkers, Risk Assessment, and Imaging Technologies, MERIT StudyRecruitingNCT03408353
• Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic TherapyRecruitingNCT02945579Not applicable
• Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton TherapyRecruitingNCT00991094
• Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis TestTerminatedNCT05243641Phase 1/2Results posted
• Contrast-Enhanced Mammography for Breast Cancer Staging in Patients Referred for a Second OpinionCompletedNCT05036083Not applicableResults posted
• Lifestyle Intervention for the Reduction of Breast Cancer Risk in Normal Weight WomenActive, not recruitingNCT04267796Not applicableResults posted
• Aromatase Inhibitor Therapy With or Without Fulvestrant for the Treatment of HR Positive Metastatic Breast Cancer With an ERS1 Activating Mutation, the INTERACT StudyTerminatedNCT04256941Phase 2Results posted
• Nab-paclitaxel and Alpelisib for the Treatment of Anthracycline Refractory Triple Negative Breast Cancer With PIK3CA or PTEN AlterationsTerminatedNCT04216472Phase 2Results posted
• Atorvastatin in Treating Patients With Stage IIb-III Triple Negative Breast Cancer Who Did Not Achieve a Pathologic Complete Response After Receiving Neoadjuvant ChemotherapyTerminatedNCT03872388Phase 2Results posted
• Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast CancerCompletedNCT03774472Phase 1/2Results posted
• Durvalumab and Tremelimumab Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Stage II-III Breast CancerCompletedNCT03132467Early Phase 1Results posted
• Mirvetuximab Soravtansine as First Line in Treating Patients With Triple Negative Breast CancerCompletedNCT03106077Phase 2Results posted
• Neratinib and Paclitaxel With or Without Pertuzumab and Trastuzumab Before Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Breast CancerTerminatedNCT03101748Phase 1/2Results posted
• Enzalutamide and Paclitaxel Before Surgery in Treating Patients With Stage I-III Androgen Receptor-Positive Triple-Negative Breast CancerCompletedNCT02689427Phase 2Results posted
• Talimogene Laherparepvec in Treating Patients With Recurrent Breast Cancer That Cannot Be Removed by SurgeryTerminatedNCT02658812Phase 2Results posted
• Women's MoonShot: Neoadjuvant Treatment With PaCT for Patients With Locally Advanced TNBCCompletedNCT02593175Phase 2Results posted
• Intraoperative Acupoint Stimulation to Prevent Post-Operative Nausea and Vomiting (PONV)CompletedNCT02473042Not applicableResults posted
• Liposomal Doxorubicin, Bevacizumab, and Everolimus in Patients With Locally Advanced TNBC With Tumors Predicted Insensitive to Standard Chemotherapy; A Moonshot InitiativeCompletedNCT02456857Phase 2Results posted
• Nintedanib For HER2-Negative Metastatic Inflammatory Breast Cancer (MIBC)TerminatedNCT02389764Phase 2Results posted
• Trial of Ra-223 Dichloride in Combination With Hormonal Therapy and Denosumab in the Treatment of Patients With Hormone-Positive Bone-Dominant Metastatic Breast CancerCompletedNCT02366130Phase 2Results posted
• Metformin for Reduction of Paclitaxel-Related Neuropathy in Patients With Breast CancerTerminatedNCT02360059Phase 2Results posted
• Feasibility of Ultrasound Microbubble Contrast-Enhanced (CEUS) Sentinel Lymph Node Imaging With Guided Biopsy in Breast Cancer PatientsCompletedNCT02321527Not applicableResults posted
• Talazoparib Before Standard Therapy in Treating Patients With Invasive, BRCA-Mutated Breast CancerCompletedNCT02282345Phase 2Results posted
• Psychosocial Outcomes and Contralateral Prophylactic Mastectomy (CPM)Active, not recruitingNCT02263014Results posted
• Denosumab for Breast Cancer With Bone MetsTerminatedNCT01952054Phase 2Results posted
• Study of Valproic Acid (VPA) vs Placebo to Shorten Time of Indwelling Pleural CatheterTerminatedNCT01900730Phase 2Results posted
• Exemestane-RAD001-MetforminTerminatedNCT01627067Phase 2Results posted
• A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation TherapyCompletedNCT01624220Not applicableResults posted
• Neoadjuvant Study of Sequential Eribulin Followed by FAC Compared to Sequential Paclitaxel Followed by FEC in Early Stage Breast Cancer Not Overexpressing HER-2CompletedNCT01593020Phase 2Results posted
• Phase II Short-term Adjuvant Therapy and Biomarker Studies With Targeted Agents in Women With Estrogen Receptor Negative Breast CancerCompletedNCT01471106Phase 2Results posted
• Cryoablation for Invasive Breast Carcinoma Following Neoadjuvant TherapyTerminatedNCT01388777Phase 2Results posted
• TPI 287 in Breast Cancer Metastatic to the BrainCompletedNCT01332630Phase 2Results posted
• Hypofractionated Radiation Therapy or Standard Radiation Therapy in Treating Patients With Ductal Breast Carcinoma In Situ or Early Invasive Breast CancerActive, not recruitingNCT01266642Phase 2Results posted
• TKI258 for Metastatic Inflammatory Breast Cancer PatientsCompletedNCT01262027Phase 2Results posted
• Panitumumab, Nab-paclitaxel and Carboplatin for HER2 Negative Inflammatory Breast CancerCompletedNCT01036087Phase 2Results posted
• Xeloda (Capecitabine) and External Beam RadiationCompletedNCT00916578Phase 2Results posted
• Trial of Fulvestrant, MK-0646, and Dasatinib for Metastatic Hormone Receptor-Positive HER2-Negative Breast CancerTerminatedNCT00903006Phase 1/2Results posted
• Personalized Treatment Selection for Metastatic Breast CancerTerminatedNCT00780676Phase 2Results posted
• Phase II Neoadjuvant in Inflammatory Breast CancerTerminatedNCT00756470Phase 2Results posted
• Phase II Study of Erlotinib, an EGFR Inhibitor in Metastatic EGFR-positive 'Triple Receptor-negative' Breast CancerTerminatedNCT00739063Phase 2Results posted
• Dasatinib in Combination With Zoledronic Acid for the Treatment of Breast Cancer With Bone MetastasisCompletedNCT00566618Phase 1/2Results posted
• Evaluate the Use of Paravertebral Block in Reconstructive Breast SurgeryCompletedNCT00542542Phase 3Results posted
• Melatonin Postoperative Sleep Study in Breast Cancer PatientsTerminatedNCT00506064Phase 1Results posted
• Paclitaxel Followed by FEC Versus Paclitaxel and RAD001 Followed by FEC In Women With Breast CancerStatus unknownNCT00499603Phase 2Results posted
• Mini-Allogeneic Peripheral Blood Progenitor Cell Transplantation For Recurrent or Metastatic Breast CancerCompletedNCT00429572Phase 2Results posted
• Sm-EDTMP and Autologous Peripheral Blood Stem Cell Transplantation for Breast Cancer Patients With Bone Only MetastasesCompletedNCT00429507Phase 2Results posted
• Goserelin Acetate Study for Ovarian Function in Patients With Primary Breast CancerTerminatedNCT00429403Phase 3Results posted
• Purged Circulating Tumor Cells (CTCs) From Metastatic Breast CancerCompletedNCT00429182Phase 2Results posted
• Herceptin and GM-CSF for Metastatic Breast CancerCompletedNCT00429104Phase 2Results posted
• Letrozole and Imatinib Mesylate in Treating Postmenopausal Participants With Estrogen or Progesterone Positive Metastatic Breast CancerCompletedNCT00338728Phase 2Results posted
• Trastuzumab and RAD001 in Patients With Human Epidermal Growth Receptor 2 (HER-2) Overexpressing Breast CancerCompletedNCT00317720Phase 1/2Results posted
• Celecoxib in Preventing Hand/Foot Syndrome Caused By Capecitabine With Metastatic Breast or Colorectal CancerTerminatedNCT00305643Phase 3Results posted
• Evaluation of Differing Taxanes/Taxane Combinations on the Outcome of Patients With Operable Breast CancerCompletedNCT00050167Phase 1Results posted
• Molecular Surveillance In Early Breast Cancer Using The Tumor-Informed ctDNA Assay Myriad Genetics Precise MRD Test; A Prospective Observational Multicenter Study (The MRD Molecular Surveillance Study)WithdrawnNCT07475923
• The Impact of Surgeon-Interpreted Intraoperative Margin Assessment During Breast Conserving Surgery on Postoperative TreatmentSuspendedNCT07140965
• Everyday Exposures: How Chemicals and Weight Impact Breast Cancer RiskActive, not recruitingNCT07137468
• A Phase Ib Study of Novel Combination (New) of Low Dose Oral CyclophoSphamide (s) to Potentiate Axatilimab (A) + Retifanlimab (R) in Treating Metastatic Triple Negative Breast Cancer (TNBC)SuspendedNCT06959537Phase 1
• Evaluating Mechanical Properties of Post-Mastectomy Skin Flaps to Estimate Reconstruction Risks, the EMPOWER StudyActive, not recruitingNCT06584396
• 3D Printed Breast Models in the Surgical Management of Breast CancerActive, not recruitingNCT05755984Not applicable
• Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) InterventionActive, not recruitingNCT05677048Not applicable
• A Phase II Study of Neoadjuvant Sacituzumab Govitecan and Pembrolizumab Therapy for Immunochemotherapy-resistant Early-stage Triple-negative Breast Cancer (TNBC)Active, not recruitingNCT05675579Phase 2
• Phase 1b Study of EZH1/2 Inhibitor Valemetostat in Combination With Trastuzumab Deruxtecan in Subjects With HER2 Low/Ultra-low/Null Metastatic Breast CancerActive, not recruitingNCT05633979Phase 1
• E-Health Support Program (PACK Health Program) in Supporting Patient Reported Symptoms in Newly Diagnosed Patients With Breast CancerCompletedNCT05549687Not applicable
• A Pilot Study to Assess the Clinical Utility of PYLARIFY PET-CT for Detecting Metastasis in Pancreatic Cancer, Hepatocellular Carcinoma and Breast CancerActive, not recruitingNCT05394259Phase 1
• A Radiotracer ([18F]FluorThanatrace) by PET/CT for the Imaging of Breast CancerActive, not recruitingNCT05226663Phase 2
• Panitumumab and Pembrolizumab in Combination With Neoadjuvant Chemotherapy for the Treatment of Stage III-IV Triple Negative Breast CancerWithdrawnNCT05177796Phase 2
• Mobile-Health Delivery of Lifestyle Interventions for Women With Breast CancerActive, not recruitingNCT05132296Not applicable
• Patient-Specific Decision Aid System for Shared Decision Making About Breast ReconstructionActive, not recruitingNCT05130580Not applicable
• Treatment Decision Making in African American Women Diagnosed With Triple Negative Breast CancerCompletedNCT05071677
• Contrast Enhanced Spectral Mammography for the Evaluation of Pathologic Nipple DischargeActive, not recruitingNCT05056844Not applicable
• Contrast-Enhanced Mammography for the Evaluation of Mammographic MicrocalcificationsActive, not recruitingNCT05046301
• Myofascial Release or Trigger Point Injections for the Reduction of Post-Mastectomy Pain SyndromeWithdrawnNCT05041751Not applicable
• Comparing the Performance of Automated Breast Ultrasonography to Hand-Held Whole Breast Ultrasonography in Breast Cancer Treatment Response AssessmentWithdrawnNCT05005936
• An Imaging Technology, Contrast-Enhanced Mammography, in Predicting Breast CancerActive, not recruitingNCT04871139Not applicable
• Precision Performance Status Assessment in Breast Cancer Patients Receiving Neoadjuvant ChemotherapyTerminatedNCT04835597