Johnson & Johnson: Osteoarthritis, Knee trials

The registry lists 32 Osteoarthritis, Knee studies with Johnson & Johnson as lead sponsor. 0 are open to participants now and 14 have results posted.

Phase 1 2Phase 2 5Phase 3 8Phase 4 9No phase 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Comparison of Alignment Achieved Using the VELYS Robotic-Assisted Solution Versus Manual Instrumentation in Total Knee ArthroplastyCompletedNCT04730271Not applicableResults posted
• ATTUNE Cementless FB Tibial Base Clinical StudyTerminatedNCT04630262Not applicableResults posted
• Efficacy and Safety Study of Transdermal Therapeutic System (TTS) Fentanyl in Participants With Osteoarthritis Knee PainCompletedNCT01742897Phase 4Results posted
• Comparison of Surgical Time and Efficiency of Total Knee ArthroplastyCompletedNCT01301950Not applicableResults posted
• An Efficacy and Safety Study for Tapentadol Extended Release (JNS024ER) in Chronic Pain ParticipantsCompletedNCT01124604Phase 2Results posted
• Alignment Comparison Between TruMatch™ Personalized Solutions and Conventional Total Knee Replacement InstrumentationCompletedNCT01108237Not applicableResults posted
• Switching Drug Therapy for the Prevention of Blood Clot Formation From Enoxaparin to Rivaroxaban After Orthopedic Surgery for Either Total Hip or Total Knee ReplacementCompletedNCT01094886Phase 3Results posted
• Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the KneeCompletedNCT00980798Phase 3Results posted
• A Study to Compare the Press Fit Condylar (P.F.C.) Sigma Rotating-platform High-flexion (RP-F) Versus the Press Fit Condylar (P.F.C.) Sigma Rotating-platform (RP) Knee ImplantsTerminatedNCT00733369Phase 4Results posted
• A Comparative Study of Tramadol Hydrochloride Plus Acetaminophen Tablets Maintenance Versus Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Maintenance in Participants With Knee OsteoarthritisCompletedNCT00635349Phase 4Results posted
• Tapentadol (CG5503)CompletedNCT00421928Phase 3Results posted
• A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol (CG5503) Prolonged-Release (PR) and Oxycodone Controlled-Release (CR) in Patients With Chronic PainCompletedNCT00361504Phase 3Results posted
• Gamma Vacuum Foil (GVF) Versus Cross-linked Polyethylene in Total Knee Arthroplasty StudyCompletedNCT00289133Not applicableResults posted
• PFC Sigma Fixed and Mobile Knee StudyTerminatedNCT00208325Phase 4Results posted
• A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-39439335 in Patients With OsteoarthritisCompletedNCT01343303Phase 1
• A Controlled Study of an Herbal Topical Patch in Treating Osteoarthritis (OA) of the KneeCompletedNCT01183624Phase 4
• Observational Study Investigating the Effectiveness of Fentanyl Matrix in Relieving Pain and Improving Function in Patients With Osteoarthritis of the Knee or HipCompletedNCT01119885
• A Safety and Tolerability Study of JNJ-42160443 in Patients With Moderate to Severe, Chronic Knee Pain From OsteoarthritisTerminatedNCT01094262Phase 2
• Treatment of Medial Compartmental Osteoarthritis Grade 1-4 With TomoFix™ Small or ConservativelyCompletedNCT01048710
• A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Osteoarthritis-related PainTerminatedNCT00973141Phase 2
• A Clinical Study to Investigate the Effect on Pain Relief of a Single Dose of JNJ-39439335 in Patients With Chronic Osteoarthritis Pain of the KneeCompletedNCT00933582Phase 1
• An Exploratory Study of Tramadol Hydrochloride in Patients With Osteoarthritis of the Knee or Low Back PainCompletedNCT00752661Phase 2
• Efficacy and Safety of Tapentadol Extended Release Tablets in the Treatment of Moderate to Severe Pain in Subjects With Knee OsteoarthritisCompletedNCT00745069Phase 2
• Long-term Study of The Press Fit Condylar (P.F.C.) Sigma Total Knee Replacement SystemTerminatedNCT00734110Phase 4
• Survivorship of the Press Fit Condylar (P.F.C.) Sigma Fixed Bearing Knee With a Cobalt Chrome Tibial TrayCompletedNCT00734019
• The Press Fit Condylar (P.F.C.) Sigma Metal-backed Versus All-polyCompletedNCT00733928Phase 4
• Outcome Study of Total Knee Arthroplasty in Asian PatientsCompletedNCT00733694Phase 4
• A Four-Week Study Comparing Acetaminophen Extended Release and Rofecoxib in the Treatment of Osteoarthritis of the KneeCompletedNCT00568295Phase 3
• A Study to Evaluate the Effectiveness and Safety of Slow Release Hydromorphone HCL for Treatment of Patients With OsteoarthritisCompletedNCT00411164Phase 3
• An Effectiveness, Safety and Quality of Life Measures With Hydromorphone HCL, Dilaudid CR (Controlled Release)CompletedNCT00399048Phase 3
• A Safety and Effectiveness Study of Acetaminophen (4000 mg/Day) and Naproxen (750 mg/Day) in the Treatment of Osteoarthritis of the Hip or KneeCompletedNCT00240773Phase 3
• P.F.C. Sigma Fixed Versus P.F.C. RP Mobile Bearing Total Knee SystemsTerminatedNCT00208286Phase 4