An observational study in Askin Tumor, Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor and Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, sponsored by Children's Oncology Group. Completed at 189 sites in 6 countries. Open to participants aged Up to 21 Years. Per ClinicalTrials.gov, last updated 2023-10-03.
Sponsored by Children's Oncology Group · Observational
This research study is collecting and storing samples of tumor tissue, bone marrow, and blood from patients with Ewing sarcoma. Collecting and storing samples of tumor tissue, bone marrow, and blood from patients with cancer to test in the laboratory may help the study of cancer in the future.
OBJECTIVES:
I. Collect biological specimens, including associated demographic and clinical data, from patients with Ewing sarcoma.
II. Provide a repository for long-term storage of Ewing sarcoma-related biological materials.
III. Make collected specimens available to qualified researchers to understand the biology of Ewing sarcoma and correlate these results with demographic and clinical data.
OUTLINE: This is a multicenter study.
Patients undergo collection of tumor specimens, bone marrow, and peripheral blood at diagnosis. Associated demographic and clinical data are collected and archived. Patients who are not enrolled on a therapeutic clinical trial are followed annually.
135 studies on the registry are indexed under Neuroectodermal Tumors, Primitive, Peripheral; 2 are open to participants now.
This study's enrollment of 908 is above the median of 200 across 13 observational studies indexed under Neuroectodermal Tumors, Primitive, Peripheral.
Browse Neuroectodermal Tumors, Primitive, Peripheral studies →Children's Oncology Group is the lead sponsor of 448 studies on the registry; 36 are open to participants now.
Of its 12 completed or terminated interventional studies of FDA-regulated products, 11 (92%) have results posted.
Counted across the registry records on this site, refreshed daily.
All patients with either newly diagnosed or recurrent Ewing sarcoma (including peripheral PNET and Askin tumor) are eligible for AEWS07B1.
Inclusion Criteria:
Diagnosis of Ewing sarcoma, including peripheral primitive neuroectodermal tumor and Askin tumor
Patients undergo collection of tumor specimens, bone marrow, and peripheral blood at diagnosis. Associated demographic and clinical data are collected and archived. Patients who are not enrolled on a therapeutic clinical trial are followed annually.
Other: Laboratory Biomarker Analysis
Correlative studies
Banking of biological specimens, including associated demographic and clinical data
Time frame: Not Provided
Showing the first 100 of 189 sites across 6 countries. Choose a country and city above to see the rest.
Ran from Feb 2008 to primary completion in Sep 2023, 187 months.
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This study is completed, as verified in Oct 2023. You cannot join it, but the record below documents what was studied.
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Neuroectodermal Tumors, Primitive, Peripheral →