Children's Hospital Medical Center, Cincinnati: Rheumatic Heart Disease trials

The registry lists 12 Rheumatic Heart Disease studies with Children's Hospital Medical Center, Cincinnati as lead sponsor. 6 are open to participants now and 0 have results posted.

Phase 2 1Phase 3 2No phase 9(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Penicillin to Prevent Early Rheumatic Heart Disease in School-Aged ChildrenNot yet recruitingNCT07798232Phase 3
• Multi-country Evaluation of Early RHD in Children Across Africa for Vaccine Trial ReadinessNot yet recruitingNCT07790302
• Testing a Registry-Based Strategy (ACT+) to Reduce Loss to Follow-Up in Rheumatic Heart Disease Screening in UgandaNot yet recruitingNCT07606131Not applicable
• Artificial Intelligence to Scale Early Rheumatic Heart Disease DetectionNot yet recruitingNCT07599956Not applicable
• A Non-Inferiority Trial of Stopping Penicillin in Early Rheumatic Heart Disease: GOAL-StopRecruitingNCT07146048Phase 3
• Accelerating Delivery of rheUmatic Heart Disease Preventive iNterventions in Northern UgandaRecruitingNCT05783375Not applicable
• Identifying Essential Elements of SAP SupportsCompletedNCT07603297Not applicable
• GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD TrialActive, not recruitingNCT05693545Phase 2
• Train the Trainer Curriculum to Scale up AI Supported Echo for RHD Screening in a Public Health SystemCompletedNCT05668611Not applicable
• Case Management and Peer Support Groups for Prophylaxis Adherence in Rheumatic Heart DiseaseCompletedNCT05502042Not applicable
• Rheumatic Heart Disease Community Streptococcal Treatment Program "RESET"CompletedNCT05276999Not applicable
• A Long-term Follow up Study for Patients Who Participated in the GOAL Trial (GOAL-Post)CompletedNCT05211024