Valsartan: all 252 studies that test it

Page 1 of 3. Open to participants first (19), then studies with results posted, then the rest; newest registration first within each.

• Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)Enrolling by invitationNCT07547878Phase 4
• Effects of VALsartan On atRIAl Mitral Regurgitation (VALORIA) - PilotRecruitingNCT07539298Phase 2/3
• Manganese-enhanced Magnetic Resonance Imaging in Takotsubo CardiomyopathyRecruitingNCT07491718Not applicable
• A Drug-Drug Interaction Study of HDM1002 and Metformin, Empagliflozin, Midazolam, Valsartan, and WarfarinRecruitingNCT07331389Phase 1
• Sacubitril/Valsartan in Patients With Prosthetic Heart Valves With Heart Failure and Reduced Ejection FractionRecruitingNCT07192341Not applicable
• TriGlytza®-01 Versus Metformin in Overweight and Obese Adults With Type 2 Diabetes and Inadequate Glycaemic Control Despite Metformin TherapyNot yet recruitingNCT07139405Phase 2
• Treatment of Moderate Ischemic Mitral Regurgitation in Patients With Coronary Artery DiseaseRecruitingNCT06917664Phase 4
• A Phase III Clinical Study of Valsartan Oral Solution for the Treatment of Hypertension in Children and AdolescentsEnrolling by invitationNCT06863987Phase 3
• Effect of Angiotensin Receptor/Neprilysin Inhibitors on Transthyretin Cardiac Amyloidosis and Heart Failure with Reduced Ejection FractionNot yet recruitingNCT06712030Phase 3
• Sacubitril-valsartan in Patients With Heart Failure With Reduced Ejection Fraction From Rural TanzaniaRecruitingNCT06704633Phase 4
• Sacubitril/Valsartan Treats Patients With Essential Hypertension and Type 2 Diabetic NephropathyNot yet recruitingNCT06501651Phase 4
• Diuretics vs. Afterload Reduction for Treatment of HeartLogic AlertsRecruitingNCT06218199Phase 4
• Bioequivalence Study of Amlodipine/Valsartan 10/160 mg Film Coated TabletsNot yet recruitingNCT06193044Phase 1
• Repurposing Valsartan May Protect Against Pulmonary HypertensionRecruitingNCT06053580Phase 2
• Determination of Drug Levels for Pharmacotherapy of Heart FailureNot yet recruitingNCT06035978Phase 4
• The Effect of Sacubitril/Valsartan Versus Ramipril on Left Ventricular Function and Remodeling in Patients With Ischemic Heart Failure With Mid-range Ejection FractionRecruitingNCT05508035Phase 3
• Enhancing the Natriuretic Peptide System in HFpEFEnrolling by invitationNCT05279742Phase 1/2
• Treating Heart Dysfunction Related to Cancer Therapy With Sacubitril/ValsartanRecruitingNCT05194111Phase 1/2
• The Effects of Sacubitril-Valsartan vs Enalapril on Left Ventricular Remodeling in ST-elevation Myocardial InfarctionNot yet recruitingNCT04912167Phase 3
• A Safety Study of Sacubitril/Valsartan in Japanese Pediatric Patients With Heart Failure Due to Systemic Left Ventricle Systolic Dysfunction Who Have Completed CLCZ696B2319E1 StudyCompletedNCT06149104Phase 3Results posted
• 24 Hour Ambulatory Cardiac Oxygen ConsumptionCompletedNCT05170061Phase 3Results posted
• Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Patients With CCCCompletedNCT04023227Phase 4Results posted
• Changes in NT-proBNP, Safety, and Tolerability in HFpEF Patients With a WHF Event (HFpEF Decompensation) Who Have Been Stabilized and Initiated at the Time of or Within 30 Days Post-decompensation (PARAGLIDE-HF)CompletedNCT03988634Phase 3Results posted
• Open-label Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With HFCompletedNCT03785405Phase 3Results posted
• Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1TerminatedNCT03738878Phase 4Results posted
• The Effects of Sacubitril/Valsartan Compared to Valsartan on LV Remodelling in Asymptomatic LV Systolic Dysfunction After MICompletedNCT03552575Phase 3Results posted
• A Randomized, Double-blind Controlled Study Comparing LCZ696 to Medical Therapy for Comorbidities in HFpEF PatientsCompletedNCT03066804Phase 3Results posted
• EntrestoTM (LCZ696) In Advanced Heart Failure (LIFE Study)CompletedNCT02816736Phase 4Results posted
• Angiotensin Receptors and Age Related Mitochondrial Decline in HIV PatientsTerminatedNCT02606279Not applicableResults posted
• Study of Efficacy and Safety of CVAA489 in Hypertensive PatientsCompletedNCT02062645Phase 4Results posted
• Efficacy and Safety of Valsartan 160mg and Rosuvastatin 20mg in Patients With Hypertension and HyperlipidemiaCompletedNCT01918332Phase 3Results posted
• Assessment of LCZ696 and Valsartan in Asian Patients With Salt-sensitive HypertensionCompletedNCT01681576Phase 2Results posted
• Efficacy, Safety and Tolerability of Multiple Doses of Valsartan in Children With Hypertension With or Without CKDCompletedNCT01617681Phase 3Results posted
• Safety and Tolerability of Valsartan in Children 6 to 17 Years of AgeCompletedNCT01365481Phase 3Results posted
• An 8-week Study to Evaluate the Dose Response of AHU377 in Combination With Valsartan 320 mg in Patients With Mild-to-moderate Systolic HypertensionCompletedNCT01281306Phase 2Results posted
• Effectiveness of Valsartan/Amlodipine (EXforge®) and Nifedipine treAtment coMparison in Treating Chinese Hypertensive PatientsCompletedNCT01167153Phase 4Results posted
• Aldosterone Breakthrough During Diovan, Tekturna, and Combination Therapy in Patients With Proteinuric Kidney DiseaseTerminatedNCT01129557Phase 4Results posted
• Valsartan/Amlodipine As Compared to Losartan Treatment in Stage 2 Systolic HypertensionCompletedNCT00931710Phase 4Results posted
• Valsartan Intensified Primary Care Reduction of Blood Pressure StudyCompletedNCT00902304Phase 4Results posted
• Genes, Fibrinolysis and Endothelial Dysfunction- Dialysis Aim 3TerminatedNCT00878969Phase 3Results posted
• 8 Weeks Study to Evaluate the Efficacy and Safety of Valsartan in Combination With Aliskiren Compared to Valsartan Alone in Patients With Stage 2 HypertensionCompletedNCT00809926Phase 4Results posted
• Study of Inflammation and Oxidative Stress in Persons Undergoing DialysisCompletedNCT00732069Phase 2Results posted
• Efficacy of a Combination of Amlodipine/Valsartan on 24H Blood Pressure Control With One Nocturnal or Diurnal Intake a DayCompletedNCT00700271Phase 4Results posted
• Safety, Tolerability, and Efficacy of Once Daily Amlodipine/Valsartan 5/80 as Compared to Amlodipine/Valsartan 5/40 or to Amlodipine 5 mg Monotherapy in Patients 65 Years of Age and Older With Essential HypertensionCompletedNCT00699192Phase 3Results posted
• Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Compared to Valsartan Monotherapy or Hydrochlorothiazide Monotherapy in Elderly (>70) With Mild-moderate Hypertension.CompletedNCT00698646Phase 4Results posted
• The Effects of Moderate vs. Aggressive Treatment With Valsartan + Amlodipine on Patients With Hypertension Uncontrolled by Angiotensin-Receptor Blocker (Herein, ARB) MonotherapyCompletedNCT00666536Phase 4Results posted
• Black Education and Treatment of Hypertension (BEAT HTN)CompletedNCT00661895Phase 4Results posted
• Cardioprotective Benefits of Carvedilol-CR or Valsartan Added to LisinoprilCompletedNCT00657241Phase 3Results posted
• Efficacy and Safety of Valsartan and Amlodipine (± HCTZ) in Adults With Moderate, Inadequately Controlled HypertensionCompletedNCT00523744Phase 3Results posted
• The Effects of Systolic Blood Pressure Lowering on Diastolic Function Using Valsartan + Amlodipine in Patients With Hypertension and Diastolic DysfunctionCompletedNCT00523549Phase 4Results posted
• A Study to Evaluate the Long-term Use of Valsartan in Children 6 Months to 5 Years Old With HypertensionCompletedNCT00457626Phase 3Results posted
• Efficacy and Safety of Valsartan in Combination With Amlodipine Compared to Losartan Plus Hydrochlorothiazide in Patients With Hypertension and Left Ventricular HypertrophyCompletedNCT00446563Phase 3Results posted
• Extension Study to Assess Long Term Safety, Tolerability, and Efficacy of Valsartan and Enalapril Combined and Alone in Children With HypertensionCompletedNCT00446511Phase 3Results posted
• Safety/Efficacy of Valsartan/Hydrochlorothiazide Combination Compared to Hydrochlorothiazide in Obese Hypertensive AdultsCompletedNCT00439738Phase 4Results posted
• Efficacy and Safety of Valsartan/Amlodipine Compared to Amlodipine in Patients With Essential HypertensionCompletedNCT00437645Phase 3Results posted
• Dose Response of Valsartan on Sitting Systolic Blood Pressure in Children 6 Months - 5 Years of Age With High Blood PressureCompletedNCT00435162Phase 3Results posted
• Effect of Valsartan Compared to Enalapril on Sitting Systolic Blood Pressure in Children With High Blood PressureCompletedNCT00433836Phase 3Results posted
• Efficacy and Safety of Valsartan and Amlodipine in Patients With Essential HypertensionCompletedNCT00425373Phase 2/3Results posted
• Efficacy/Safety of Valsartan Plus Amlodipine and Valsartan Alone in Patients With HypertensionCompletedNCT00413413Phase 3Results posted
• Efficacy and Safety of Aliskiren and Valsartan Versus Placebo in Patients Stabilized Following an Acute Coronary SyndromeCompletedNCT00409578Phase 2Results posted
• Safety and Efficacy of Valsartan vs Atenolol and Hydrochlorothiazide Combination on Blood Flow in Hypertensive PatientsCompletedNCT00396656Phase 3Results posted
• Evaluation of Heart Failure Treatment Guided by N-terminal Pro B-type Natriuretic Peptide (NTproBNP) vs Clinical Symptoms and Signs AloneCompletedNCT00391846Phase 4Results posted
• Effect of Valsartan on Carotid Artery DiseaseCompletedNCT00208767Phase 2Results posted
• Efficacy and Safety of Valsartan Versus Amlodipine in Postmenopausal Women With HypertensionCompletedNCT00171054Phase 4Results posted
• Add-on Effects of Valsartan on Morbi- Mortality (KYOTO HEART Study)CompletedNCT00149227Phase 4Results posted
• Long-term Study of Nateglinide+Valsartan to Prevent or Delay Type II Diabetes Mellitus and Cardiovascular ComplicationsCompletedNCT00097786Phase 3Results posted
• Effectiveness of Valsartan Alone vs Combination Therapy in Hypertensive Heart DiseaseCompletedNCT07544888Phase 1
• The Effect of Sacubitril and Valsartan on Heart Function in Chronic Hemodialysis Patients With HFpEFCompletedNCT07417215Phase 4
• Comparing Bisoprolol and Valsartan-Amlodipine for HypertensionCompletedNCT07327749Phase 4
• Comparative Assessment of Efficacy & Safety of Sacubitril/Valsartan Versus Ramipril in Patients With Renal Dysfunction Hospitalized With Acute Decompensated Heart FailureCompletedNCT07023016Phase 2/3
• Sacubitril/Valsartan Versus Valsartan in Heart FailureCompletedNCT05881720Phase 4
• Drug-Drug Interaction Study of Chiglitazar in Healthy Subjects.CompletedNCT05681273Phase 1
• Effects and Safety of Sacubitril/Valsartan on Refractory HypertensionStatus unknownNCT05545059Phase 3
• Safety and Tolerability of Sacubitril/Valsartan in Heart Failure Patient With Reduced Ejection FractionCompletedNCT05387967Phase 4
• Lifestyle and Pharmacological Interventions in Hypertrophic CardiomyopathyCompletedNCT05366101Phase 2/3
• Study to Evaluate the Efficacy and Safety of SPH3127 In Patients With Mild-moderate Essential HypertensionCompletedNCT05359068Phase 3
• Exercise-induced Erythropoiesis: the Mechanistic of Angiotensin IIStatus unknownNCT05269615Phase 4
• Sacubitril/Valsartan for CKD5 Stage Dialysis PatientsCompletedNCT05243199Phase 4
• ARNI Versus plAcebo in Patients With Congenital sYStemic Right Ventricle Heart FailureTerminatedNCT05117736Not applicable
• The Effect of Angiotensin Receptor-Neprilysin Inhibition on Cardiac Fibrosis in Patients With HFpEFStatus unknownNCT05089539Phase 2
• Sacubitril/Valsartan Versus Amlodipine in Hypertension and Left Ventricular Hypertrophy.Status unknownNCT04929600Phase 4
• A Study to Evaluate the DDI of DBPR108 With Metformin,Glibenclamide,Valsartan, or Simvastatin in Healthy SubjectsCompletedNCT04859452Phase 1
• Effect of LCZ696 on Urinary Microalbumin and Pulse Wave Velocity in Perimenopausal Patients With HypertensionStatus unknownNCT04800081Not applicable
• Renin Angiotensin System Blockade in Renal Transplant Patients With Presence of PECs in UrineStatus unknownNCT04769778Phase 4
• Effect of Adding Renin-Angiotensin System Inhibitors to Standard Antidiabetic Therapy on Glycemic Control in Patients With Type 2 Diabetes EllitusCompletedNCT04707508Phase 4
• Open-label Extension Study for CLCZ696G2301 (PARADISE-MI)WithdrawnNCT04637555Phase 3
• Study on the Treatment of Children With Purpura Nephritis With Huaiqihuang GranulesStatus unknownNCT04623866Early Phase 1
• Influence of Sacubitril/Valsartan on Autonomic Cardiac Nervous System in Heart Failure Patients: an Exploratory StudyCompletedNCT04587947Not applicable
• The Effect of Sacubitril/Valsartan on Cardiovascular Events in Dialysis Patients and Efficacy Prediction of Baseline LVEF ValueStatus unknownNCT04572724Phase 4
• Early Treatment of ARNI on Myocardial Remodeling and ProgressStatus unknownNCT04342351Phase 4
• Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVID-19) Infection DiseaseTerminatedNCT04335786Phase 4
• Effect of Sacubitril/Valsartan on Reduced Right Ventricular Ejection Fraction in Patients With CTDStatus unknownNCT04197050Phase 4
• Comparison of BNP and NT-proBNP in the Management of Patients With Chronic and Acute Heart FailureStatus unknownNCT04107220Not applicable
• A Bioequivalence Study of Valsartan / Amlodipine From Valsartan and Amlodipine Tablets (Hua Yuan Pharmaceutical LLC, China) and Valsartan and Amlodipine Tablets (Ⅰ) (Novartis Pharma Schweiz AG, Switzerland)Status unknownNCT04085627Phase 1
• Valsartan Versus Amlodipine Effect on Left Ventricular Multidirectional Deformation and Adipocytokines LevelCompletedNCT03990480Phase 4
• Effect of Neprilysin on Glucagon-Like Peptide-1 in Patients With Type 2 DiabetesCompletedNCT03893526Phase 4
• Sacubitril/Valsartan vs Lifestyle in Hypertrophic CardiomyopathyCompletedNCT03832660Phase 2
• Prevention of Cardiac Dysfunction During Breast Cancer TherapyCompletedNCT03760588Phase 2
• Evaluation of Superiority of Valsartan+Celecoxib+Metformin Over Metformin Alone in Type 2 Diabetes PatientsWithdrawnNCT03686657Phase 1/2
• Clinical Trial to Assess the Pharmacokinetic Characteristics of Lodivixx Tab. 5/160mg in Healthy Male Subjects (N=27)CompletedNCT03648333Phase 1

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