Tyrosine Kinase Inhibitors: all 10,469 studies that test it
Page 68 of 105. Open to participants first (1,909), then studies with results posted, then the rest; newest registration first within each.
- A Drug Drug Interaction Study Between PF-06826647 And Oral Contraceptive Steroids In Healthy Female ParticipantsCompletedNCT04134715Phase 1
- Study of Cabozantinib Efficacy, Safety and Tolerability in Metastatic Renal Carcinoma in Aged Fragile Patients: CABOMAYOR StudyCompletedNCT04134390Phase 2
- To Evaluate the Efficacy of Afatinib in Advanced Lung Squamous Cell Carcinoma With EGFR Sensitive MutationStatus unknownNCT04132102Phase 4
- Baricitinib for the Prophylaxis of Graft-Versus-Host Disease After Peripheral Blood Hematopoietic Cell TransplantationCompletedNCT04131738Phase 1
- Phase II Study With Cabozantinib in Patients With RET Positive NSCLCStatus unknownNCT04131543Phase 2
- Gemcitabine and Z650 in Treating Patients With Metastatic or Recurrent Pancreatic CancerTerminatedNCT04131192Phase 1
- TAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion MutationsCompletedNCT04129502Phase 3
- Appatinib Combined With S-1 in the Treatment of Small Cell Lung CancerStatus unknownNCT04128800Phase 2
- Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic SyndromeActive, not recruitingNCT04128748Phase 1/2
- A Study to Evaluate the Tolerance and Pharmacokinetics of TQB3804 in Subjects With Advanced Malignant TumorsStatus unknownNCT04128085Phase 1
- Itacitinib for the Prevention of Graft Versus Host Disease in Patients Undergoing Donor Stem Cell TransplantationWithdrawnNCT04127721Phase 2
- Lenvatinib Plus TACE Versus Sorafenib Plus TACE for HCC With PVTTStatus unknownNCT04127396Phase 4
- Activity of Lorlatinib Based on ALK Resistance Mutations Detected on Blood in ALK Positive NSCLC PatientsActive, not recruitingNCT04127110Phase 2
- Apatinib Combined With Chemotherapy in the Treatment of Soft Tissue SarcomaStatus unknownNCT04126811Phase 2
- The Absorption, Metabolism and Excretion of [14C] HQP1351 in HumansCompletedNCT04126707Phase 1
- A Pivotal Study of HQP1351 in Patients With Chronic Myeloid Leukemia in Chronic PhaseCompletedNCT04126681Phase 2
- Neoadjuvant Study of Pyrotinib in HER-2 Positive Breast CancerActive, not recruitingNCT04126525Phase 2
- Roll-over Study to Continue Treatment With the Investigational Drug Rogaratinib and to Further Test Its SafetyCompletedNCT04125693Phase 2
- Combination Therapy of Sintilimab and Anlotinib as a First-line Treatment in Advanced NSCLC (SUNRISE)Status unknownNCT04124731Phase 2
- A Study to Evaluate the Amount of Drug That Becomes Available in the Blood Circulation When Savolitinib is Administered Alone and in Combination With ItraconazoleCompletedNCT04121910Phase 1
- MIcroglial Colony Stimulating Factor-1 Receptor (CSF1R) in Alzheimer's DiseaseTerminatedNCT04121208Phase 1
- Study of the Apatinib Combine With POF Versus POF in Gastric CancerStatus unknownNCT04121039Phase 2
- Ruxolitinib as a Salvage Therapy for Hemophagocytic LymphohistiocytosisStatus unknownNCT04120090Phase 3
- Toripalimab Combined With Axitinib as Neoadjuvant Therapy in Patients With Non-metastatic Locally Advanced Nonmetastatic Clear Cell Renal Cell CarcinomaCompletedNCT04118855Phase 2
- A Study in Healthy Subjects to Assess the Pharmacokinetics of Savolitinib When Administered Alone and in Combination With RifampicinCompletedNCT04118842Phase 1
- Zanubrutinib (BGB-3111) in Participants With Previously Treated B-Cell Lymphoma Intolerant of Prior Bruton Tyrosine Kinase Inhibitor (BTKi) TreatmentCompletedNCT04116437Phase 2
- A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell LymphomaActive, not recruitingNCT04115631Phase 2
- The Effects Diflunisal on the Levels of BMS-986165 in Healthy ParticipantsCompletedNCT04113668Phase 1
- A Clinical Trial to Assess the Efficacy and Safety of the Combination of a Drug Call Quizartinib With Chemotherapy (FLAG-IDA) in Patients With Acute Myeloid Leukemia That Has Not Responded to the First Treatment or That Has Returned After the First TreatmentStatus unknownNCT04112589Phase 1/2
- A Study of Sequential Anlotinib Followed by EP Regimen Plus Concurrent Radiotherapy for Unresectable Stage III Non-small Cell Lung CancerStatus unknownNCT04111913Phase 2
- Lorlatinib After Failure of First-line Second-generation ALK Kinase Inhibitor in Patients With Advanced ALK-positive Non-small Cell Lung CancerCompletedNCT04111705Phase 2
- A Study to Demonstrate the Equivalence of the Tofacitinib Oral Solution to the Tablet Formulation in Healthy Participants.CompletedNCT04111614Phase 1
- Regorafenib Plus PD-1 Inhibitor in Patients With Colorectal CancerStatus unknownNCT04110093Phase 1/2
- IN10018 Monotherapy and Combination Therapy for Metastatic MelanomaCompletedNCT04109456Phase 1
- Trial to Compare Efficacy and Safety of Chemotherapy/Quizartinib vs Chemotherapy/Placebo in Adults FMS-like Tyrosine Kinase 3 (FLT3) Wild-type Acute Myeloid Leukemia (AML)CompletedNCT04107727Phase 2
- Efficacy and Safety of Anlotinib in Patients With Advanced Gastrointestinal Stromal Tumor After Failure of Imatinib: a Prospective, Single Arm and Multicenter TrialStatus unknownNCT04106024Phase 2
- Safety and Tolerability Study of Cerdulatinib Gel, 0.37% in Adults With VitiligoCompletedNCT04103060Phase 2
- Apatinib, Irinotecan and S-1 (ApaIRIS) in Treating Patients With Metastatic Pancreatic Cancer After AG RegimenStatus unknownNCT04101929Phase 2
- Study to Assess Pharmacokinetics, Safety and Tolerability of PF-04965842 in Chinese Healthy ParticipantsCompletedNCT04099563Phase 1
- Mass Balance and Pharmacokinetics Study of Derazantinib in Healthy Male SubjectsCompletedNCT04098692Phase 1
- A Study to Evaluate the Effects of Single and Multiple Oral Doses of GLPG3667CompletedNCT04097938Phase 1
- A Phase Ⅱ Trial of Pyrotinib Combination With CDK4/6 Inhibitor SHR6390 in Patients Prior Trastuzumab-treated Advanced HER2-Positive Breast CancerStatus unknownNCT04095390Phase 2
- Acalabrutinib With Rituximab and Lenalidomide in Relapsed/Refractory B-cell Non-Hodgkin LymphomaCompletedNCT04094142Phase 2
- Study Evaluating Pharmacokinetics and Mass Balance of [14C]-CTP-543 in Healthy Adult Male VolunteersCompletedNCT04092712Phase 1
- A Study of PF-06651600 Effect on Rosuvastatin Pharmacokinetics in Healthy ParticipantsCompletedNCT04092595Phase 1
- A Study to Investigate the Effect of Multiple Doses of Itraconazole on the Pharmacokinetics of PF-06700841 in Healthy ParticipantsCompletedNCT04090047Phase 1
- Apatinib Plus Sintilimab in Advanced Gastric Cancer Refractory to at Least Two Previous Chemotherapy RegimensStatus unknownNCT04089657Phase 2
- A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA)Active, not recruitingNCT04088396Phase 3
- Pyrotinib Combined With Trastuzumab Plus Aromatase Inhibitor in Treatment of Breast CancerStatus unknownNCT04088110Phase 2
- An Investigational Study to Determine the Drug Level Profile of BMS-986165 in Healthy Male Volunteers Following Transporter Inhibition.CompletedNCT04086719Phase 1
- Alisertib in Combination With Osimertinib in Metastatic EGFR-mutant Lung CancerCompletedNCT04085315Phase 1
- Study of Crizotinib for ROS1 and MET Activated Lung CancerCompletedNCT04084717Phase 2
- Anlotinib Hydrochloride Capsules Combined With CAPEOX in RAS and BRAF Wild-type mCRC PatientsCompletedNCT04080843Phase 2
- Study of Anlotinib After Lenvatinib in Patients With Hepatocellular CarcinomaStatus unknownNCT04080154Phase 2
- A Study of Lazertinib as Monotherapy or in Combination With Amivantamab in Participants With Advanced Non-small Cell Lung CancerActive, not recruitingNCT04077463Phase 1
- Brigatinib in ALK-positive NSCLC Identified Via Blood-based AssaysActive, not recruitingNCT04074993Phase 2
- A Study of Rivoceranib and Trifluridine/Tipiracil for Metastatic Colorectal Cancer (mCRC)TerminatedNCT04073615Phase 1
- Study of Anlotinib Hydrochloride Capsule in Subjects With Small Cell Lung CancerStatus unknownNCT04073550Phase 3
- Study of Anlotinib Hydrochloride Capsule Combined With Chemotherapy in Subjects With Squamous Non-small Cell Lung CancerStatus unknownNCT04073537Phase 3
- Study of Alofanib in Patients With Metastatic Gastric CancerStatus unknownNCT04071184Phase 1
- Itacitinib and Tocilizumab for Steroid Refractory Acute Graft Versus Host DiseaseTerminatedNCT04070781Phase 1
- Safety and Efficacy of Ponatinib Followed by Imatinib in Patients With Chronic Myelogenous Leukemia in Chronic PhaseActive, not recruitingNCT04070443Phase 2
- Sorafenib Plus Toripalimab for Unresectable HCC With Portal Vein Tumor ThrombusStatus unknownNCT04069949Phase 1/2
- Camrelizumab /Apatinib for Recurrent Platinum-resistant Ovarian CancerStatus unknownNCT04068974Phase 2
- Camrelizumab Combined With Apatinib in the Treatment of Patients With Advanced Gastric Cancer and Colorectal CancerStatus unknownNCT04067986Phase 1/2
- Pyrotinib or Trastuzumab Plus Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast CancerTerminatedNCT04066790Phase 2
- Cabozantinib in Patients With Locally Advanced or Metastatic Urothelial Cell Carcinoma.TerminatedNCT04066595Phase 2
- TACE Combined With Anlotinib Treatment of Middle-advanced Hepatocellular Carcinoma (HCC) PatientsStatus unknownNCT04066543Phase 2
- A Study to Determine the Pharmacokinetic Profile of BMS-986165 TabletsCompletedNCT04065932Phase 1
- Paclitaxel and DDP Combined With Anlotinib in the First-line Treatment for Patients With Advanced Esophageal Squamous Cell Carcinoma（ESCC）.Status unknownNCT04063683Phase 2
- Phase 2 Study of Pyrotinib in Previously Treated Patients With NSCLC Having EGFR or ERBB2 Exon 20 Insertion MutationStatus unknownNCT04063462Phase 2
- Tofacitinib for Reduction of Spinal Inflammation in Patients With Psoriatic ArthritiS PresenTing With Axial InvOlvementStatus unknownNCT04062695Phase 2
- First Line Therapy for High Risk Acute GVHDCompletedNCT04061876Phase 2
- A Study to Determine the Efficiency For Brain Metastasis NSCLC Patients Treated With Icotinib Alone or Combined With Radiation TherapyStatus unknownNCT04058704Phase 3
- A Phase I Trial of Simmitinib in Advanced Solid TumorsStatus unknownNCT04058587Phase 1
- Study of TQ-B3139 in Subjects With Anaplastic Lymphoma Kinase (ALK) Positive Non-Small Cell Lung Cancer (NSCLC) Previously Treated With CrizotinibStatus unknownNCT04056572Phase 2
- A Study to Investigate the Effects of Cytochrome P450 1A2 Induction by Ritonavir on BMS-986165 Drug Levels and Effects in Healthy ParticipantsCompletedNCT04055506Phase 1
- The Impact on Recurrence Risk of Adjuvant Lenvatinib for Patients With Hepatocellular Carcinoma And Microvascular Invasion (MVI) After Hepatectomy : A Random, Controlled, Stage III Clinical Trial.Status unknownNCT04053972Phase 3
- To Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of ABN401 in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer Harboring c-MET DysregulationCompletedNCT04052971Phase 1
- Anlotinib Hydrochloride Combined With Sintilimab Injection in the Treatment of Advanced Hepatocellular Carcinoma (HCC)Status unknownNCT04052152Phase 2
- Regorafenib in Bevacizumab Refractory Recurrent GlioblastomaCompletedNCT04051606Phase 2
- Camrelizumab Combined With Apatinib for Recurrent Resistant GTNCompletedNCT04047017Phase 2
- HAIC Plus Lenvatinib and Toripalimab for Advanced HCCCompletedNCT04044313Phase 2
- Poziotinib in Patients With NSCLC Having EGFR or HER2 Exon 20 Insertion MutationTerminatedNCT04044170Phase 2
- Consolidation Treatment With Ponatinib 15 mg on Treatment Free-Remission Rate in Patients With Chronic Myeloid LeukemiaStatus unknownNCT04043676Phase 2
- Sintilimab Combined With Lenvatinib in Local Advanced Hepatocellular CarcinomaStatus unknownNCT04042805Phase 2
- Anlotinib Hydrochloride Versus Imatinib Mesylate in Locally Advanced, Unresectable or Metastatic ChordomaStatus unknownNCT04042597Phase 2
- A Study to Evaluate Lucitanib in Combination With Nivolumab in Patients With a Solid TumorSuspendedNCT04042116Phase 1/2
- A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative NeoplasmActive, not recruitingNCT04041050Phase 1
- Rogaratinib for BCG Refractory High Risk Non-Muscle Invasive Bladder Cancer With FGFR1/2 OverexpressionWithdrawnNCT04040725Phase 2
- A Phase 1/2 Trial of CLN-081 in Patients With Non-Small Cell Lung CancerActive, not recruitingNCT04036682Phase 1/2
- Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With PsoriasisCompletedNCT04036435Phase 3
- Combination Camrelizumab (SHR-1210) and Apatinib for Downstaging/Bridging of HCC Before Liver TransplantStatus unknownNCT04035876Phase 1/2
- Pyrotinib Plus Fulvestrant in Patients With HR+/HER2+ Metastatic Breast Cancer (Pyrotinib+Fulvestrant )Status unknownNCT04033172Phase 2
- Crizotinib in c-MET Mutation Metastatic/Recurrent/Persistent Endometrial CancerTerminatedNCT04030429Phase 2
- Regorafenib and PD-1 Antibody in Combination With Radiotherapy for pMMR/MSS Metastatic Colorectal CancerStatus unknownNCT04030260Phase 2
- Gefitinib in Combination With Anlotinib or Placebo in Previously Untreated EGFR-mutant NSCLCStatus unknownNCT04028778Phase 3
- Phase 2 Study of Dacomitinib in NSCLCActive, not recruitingNCT04027647Phase 2
- A Study of Gilteritinib Versus Midostaurin in Combination With Induction and Consolidation Therapy Followed by One-year Maintenance in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndromes With Excess Blasts-2 With FLT3 Mutations Eligible for Intensive ChemotherapyActive, not recruitingNCT04027309Phase 3
- BAriCitinib Healing Effect in earLy pOlymyalgia RheumaticaCompletedNCT04027101Phase 2