Tyrosine Kinase Inhibitors: all 10,469 studies that test it
Page 66 of 105. Open to participants first (1,909), then studies with results posted, then the rest; newest registration first within each.
- Clinical Trial to Evaluate Light-induced Skin Reactions After Application of Delgocitinib CreamCompletedNCT04361136Phase 1
- Assessing the Pharmacokinetics Effects of Food on ASK120067 in Single Oral Administration in Chinese Healthy SubjectsCompletedNCT04360915Phase 1
- Baricitinib Therapy in COVID-19CompletedNCT04358614Phase 2/3
- Gefitinib With Anlotinib in Advanced Non-squamous NSCLC Patients With Uncleared Plasma ctDNA EGFRm After First-line Treatment With GefitinibStatus unknownNCT04358562Phase 2
- Molecularly Targeted Umbrella Study in Luminal Advanced Breast CancerStatus unknownNCT04355858Phase 2
- A STUDY TO EVALUATE THE EFFECT OF PF-06651600 ON PHARMACOKINETICS OF SINGLE DOSE SUMATRIPTAN IN HEALTHY PARTICIPANTS.CompletedNCT04355845Phase 1
- Almonertinib as First-line Treatment in Patients With EGFR+ Positive Pulmonary Adenosquamous Carcinoma or Combined Adenocarcinoma and Squamous Cell CarcinomaStatus unknownNCT04354961Phase 2
- Ruxolitinib to Combat COVID-19WithdrawnNCT04354714Phase 2
- Comparison of MAPI+Camrelizumab Versus API+Apatinib Versus MAPI in Patients With a Poor Response to Preoperative Chemotherapy for Newly Diagnosed High-grade OsteosarcomaStatus unknownNCT04351308Phase 2
- First in Human SAD and MAD Study of Inhaled TD-0903, a Potential Treatment for ALI Associated With COVID-19CompletedNCT04350736Phase 1
- Apatinib Combined With PD-1 in the Treatment of Recurrent or Metastatic Nasopharyngeal CarcinomaCompletedNCT04350190Phase 2
- A Study to Assess Single and Multiple Doses of IkT-148009 in Healthy Elderly Participants and Parkinson's PatientsCompletedNCT04350177Phase 1
- Study of Ruxolitinib Plus Simvastatin in the Prevention and Treatment of Respiratory Failure of COVID-19.CompletedNCT04348695Phase 2
- Safety and Efficacy of Ruxolitinib for COVID-19WithdrawnNCT04348071Phase 2/3
- Study to Evaluate the Efficacy and Safety of Camrelizumab and Famitinib in Patients With Advanced Solid TumorCompletedNCT04346381Phase 2
- A Phase II Study in Patients With Alopecia AreataCompletedNCT04346316Phase 2
- Clinical Trial to Evaluate Efficacy of 3 Types of Treatment in Patients With Pneumonia by COVID-19Status unknownNCT04346147Phase 2
- A Phase III Clinical Trial of AK105 Injection Combined With Anlotinib Hydrochloride Capsules Versus Sorafenib in Subjects With Advanced Hepatocellular Carcinoma (HCC)Active, not recruitingNCT04344158Phase 3
- A Food Effect Study of Apatinib Mesylate in Healthy SubjectsCompletedNCT04341090Phase 1
- Safety and Efficacy of Baricitinib for COVID-19WithdrawnNCT04340232Phase 2/3
- An Open Label, Multicenter, Phase II Study of Dacomitinib for EGFR Mutated Non-Small Cell Lung Cancer (NSCLC) With Brain MetastasesStatus unknownNCT04339829Phase 2
- A Study of TQ05105 Tablets in Subjects With Myeloproliferative NeoplasmsCompletedNCT04339400Phase 1
- Ruxolitinib in Covid-19 Patients With Defined HyperinflammationCompletedNCT04338958Phase 2
- Efficacy and Safety of Nintedanib in the Treatment of Pulmonary Fibrosis in Patients With Moderate to Severe COVID -19Status unknownNCT04338802Phase 2
- Glumetinib Combined With Osimertinib in the Treatment of Relapsed and Metastatic Non-small Cell Lung Cancer Patients Who Failed to Receive EGFR InhibitorsStatus unknownNCT04338243Phase 1/2
- A Safety and Efficacy Study of CC-90009 Combinations in Subjects With Acute Myeloid LeukemiaTerminatedNCT04336982Phase 1
- A Phase 3 Study Comparing Carelizumab Plus Nab-paclitaxel and Apatinib, Carelizumab Plus Nab-paclitaxel, and Nab-paclitaxel in Patients With Advanced Triple Negative Breast Cancer.TerminatedNCT04335006Phase 3
- Palbociclib, Trastuzumab,Pyrotinib and Fulvestrant Treatment in Patients With Brain Metastasis From ER/PR Positive, HER-2 Positive Breast Cancer: A Multi-center, Prospective Study in ChinaStatus unknownNCT04334330Phase 2
- Treatment of SARS Caused by COVID-19 With RuxolitinibCompletedNCT04334044Phase 1/2
- A Study to Evaluate the Efficacy and Safety of SHR0302 in Patients With Rheumatoid ArthritisCompletedNCT04333771Phase 3
- TOFAcitinib in SARS-CoV2 PneumoniaStatus unknownNCT04332042Phase 2
- Study of the Efficacy and Safety of Ruxolitinib to Treat COVID-19 PneumoniaTerminatedNCT04331665Not applicable
- Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas AdenocarcinomaActive, not recruitingNCT04331041Phase 2
- Treatments for COVID-19: Canadian Arm of the SOLIDARITY TrialStatus unknownNCT04330690Phase 3
- A Study of Steady-state Carbamazepine on the Single-dose of Erdafitinib Tablets in Healthy Adult ParticipantsCompletedNCT04330248Phase 1
- Bioequivalency Study of CM082 Tablet in Healthy VolunteersCompletedNCT04328506Phase 1
- A Study of TQ05105 Tablets in Subjects With Hemophagocytic Lymphohistiocytosis（HLH）Status unknownNCT04326348Phase 1
- A Study of AL2846 Versus Zoledronic Acid in Subjects With Advanced Non-Small Cell Lung Cancer With Bone MetastasisStatus unknownNCT04325776Phase 2
- A Study of TQB2450 in Subjects With Stage III Non-Small Cell Lung Cancer(NSCLC)Status unknownNCT04325763Phase 3
- CYTO Reductive Surgery in Kidney Cancer Plus Immunotherapy and Targeted Kinase InhibitionActive, not recruitingNCT04322955Phase 2
- A Pharmacokinetic Interaction Study Between Apatinib Mesylate and Transporter Pgp Substrate Digoxin in Advanced Solid Tumor SubjectsCompletedNCT04322552Phase 1
- Treatment of Moderate to Severe Coronavirus Disease (COVID-19) in Hospitalized PatientsActive, not recruitingNCT04321993Phase 2
- Lenvatinib in Locally Advanced Invasive Thyroid CancerCompletedNCT04321954Phase 2
- Baricitinib in Symptomatic Patients Infected by COVID-19: an Open-label, Pilot Study.Status unknownNCT04320277Phase 2/3
- Advancing Brigatinib Properties in ALK+ NSCLC Patients by Deep PhenotypingCompletedNCT04318938Phase 2
- Efficacy and Safety of Toripalimab (JS001) Combined With Pemetrexed and Anlotinib for Patients With T790M Positive Non-Small Cell Lung Cancer After Osimertinib ResistanceStatus unknownNCT04316351Phase 2
- A Drug-drug Interaction Trial of Loperamide Pharmacokinetics Effect on Pyrotinib MaleateCompletedNCT04315116Phase 1
- Relative Bioavailability (rBA) of Evobrutinib Intended Commercial and Clinical Tablets, and Effect of Food on Intended Commercial TabletsCompletedNCT04314024Phase 1
- Effects of Tofacitinib vs Methotrexate on Rheumatoid Arthritis Interstitial Lung DiseaseTerminatedNCT04311567Phase 4
- Combination of Regorafenib and Nivolumab in Unresectable Hepatocellular CarcinomaCompletedNCT04310709Phase 2
- Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung CancerActive, not recruitingNCT04310007Phase 2
- Drug-drug Interaction Study of CTP-543 and Oral Contraceptives in Healthy Female SubjectsCompletedNCT04309643Phase 1
- Anlotinib Neoadjuvant Treatment in Locally Advanced Thyroid CancerStatus unknownNCT04309136Phase 2
- Saracatinib Trial TO Prevent FOPActive, not recruitingNCT04307953Phase 2
- A Study of TQ-B3101 in Subjects With Relapsed or Refractory Anaplastic Large Cell Lymphoma (ALCL)Status unknownNCT04306887Phase 2
- A Study to Compare the Taste and Levels in Blood Plasma of BMS-986165 When Taken as Different Formulations by Healthy Adult ParticipantsCompletedNCT04305899Phase 1
- Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's LymphomasTerminatedNCT04305444Phase 2
- A Study of ICP-022 in Patients With Systemic Lupus Erythematosus (SLE)CompletedNCT04305197Phase 1/2
- A Study of MIL62 Combined With Orelabrutinib for the Treatment of R/R CD20+B Cell LymphomaActive, not recruitingNCT04304040Phase 1/2
- A Phase II Trial of Camrelizumab in Combination With Apatinib and Eribulin in Patients With Advanced TNBCStatus unknownNCT04303741Phase 2
- Anlotinib in Combination With PD1 With Gemcitabine Plus(+)Cisplatin for Unresectable or Metastatic Biliary Tract CancerStatus unknownNCT04300959Phase 2
- Efficiency of Methotrexate and Tofacitinib in Mild and Moderate PatientsStatus unknownNCT04299971Phase 4
- A Study to Assess the Safety and Efficacy of Lenvatinib as First-line Treatment in Participants With Unresectable HCCCompletedNCT04297254Phase 4
- Fruquintinib as a Maintenance Therapy Following First-line Treatment for Metastatic Colorectal CancerStatus unknownNCT04296019Phase 2
- Pharmacokinetics and Safety of SHR0302 in Patients With Hepatic ImpairmentCompletedNCT04293029Phase 1
- A Food Effect Study of SHR1459 on Healthy Chinese Adult SubjectsCompletedNCT04291846Phase 1
- Neoadjuvant Chemotherapy With Pyrotinib, Epirubicin and Cyclophosphamide Followed by Taxanes and Trastuzumab for HER-2+ Breast CancerActive, not recruitingNCT04290793Phase 2/3
- HMPL-453 in Advanced Malignant MesotheliomaStatus unknownNCT04290325Phase 2
- Study of CAbozantinib in Combination with AtezolizumaB for Muscle-Invasive BladdEr CancerActive, not recruitingNCT04289779Phase 2
- Pembrolizumab Plus Lenvatinib In Second Line and Third Line Malignant Pleural mesotheLioma PatientsActive, not recruitingNCT04287829Phase 2
- Necitumumab and Trastuzumab in Combination With Osimertinib for the Treatment of Refractory Epidermal Growth Factor Receptor (EGFR)-Mutated Stage IV Non-small Cell Lung CancerActive, not recruitingNCT04285671Phase 1/2
- PD-1 Combined With Dasatinib for as Third-line Treatment for ARID1A Mutation Advanced NSCLCStatus unknownNCT04284202Phase 2
- Study of Anti-PD-1 Antibody Multimodal Combination as First-line Treatment on Time Window of Advanced Solid TumorStatus unknownNCT04282278Phase 2
- Study in Healthy Adult Male Participants to Gather Information How the Human Body Absorbs, Distributes and Excretes the Study Drug Selitrectinib Including the Effect of the Interaction of Food With the Study Drug on the Human BodyCompletedNCT04275960Phase 1
- A Study of Mavorixafor in Combination With Ibrutinib in Participants With Waldenstrom's Macroglobulinemia (WM) Whose Tumors Express Mutations in MYD88 and CXCR4CompletedNCT04274738Phase 1
- Anlotinib Plus Sintilimab as First-line Treatment for Patients With Advanced Colorectal Cancer (APICAL-CRC)CompletedNCT04271813Phase 2
- Fecal Microbiota Transplantation With Ruxolitinib and Steroids as an Upfront Treatment of Severe Acute Intestinal GVHDTerminatedNCT04269850Phase 1/2
- Targeted Treatment for RET Fusion-Positive Advanced Non-Small Cell Lung Cancer (A LUNG-MAP Treatment Trial)Active, not recruitingNCT04268550Phase 2
- Conversion Therapy of Sintilimab in Combination With Apatinib and Chemotherapy in Stage IV Gastric CancerActive, not recruitingNCT04267549Phase 2
- Effect Of Multiple Dose PF-06700841 On The Pharmacokinetics Of Single Dose Oral Contraceptive SteroidsCompletedNCT04267250Phase 1
- Study to Evaluate the Effect of Repeat-Dose Rifampin on the Pharmacokinetics (PK) of PF-06651600CompletedNCT04266509Phase 1
- Study of Infigratinib in Children With AchondroplasiaCompletedNCT04265651Phase 2
- Efficacy and Safety of Carfilzomib in Combination With Ibrutinib vs Ibrutinib in Waldenström's MacroglobulinemiaActive, not recruitingNCT04263480Phase 2
- Apatinib for Inoperable Advanced ChondrosarcomaCompletedNCT04260113Not applicable
- Pharmacokinetics, Safety, and Efficacy of Brigatinib Monotherapy in Pediatric and Young Adult Participants With ALK+ Anaplastic Large Cell Lymphoma, Inflammatory Myofibroblastic Tumors or Other Solid TumorsWithdrawnNCT04260009Phase 1/2
- A Study of Avelumab In Combination With Axitinib in Patients With Unresectable/Metastatic Gastrointestinal Stromal Tumor After Failure of Standard TherapyCompletedNCT04258956Phase 2
- Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid LeukemiaActive, not recruitingNCT04258943Phase 1/2
- Camrelizumab in Combination With Apatinib Mesylate, Paclitaxel-albumin and S-1 for Translational Treatment of Gastric CancerStatus unknownNCT04258644Phase 2
- Phase 1 Study of Pemigatinib in Patients With Advanced Malignancies With FGF/FGFR AlterationsCompletedNCT04258527Phase 1
- A Study of PLB1001 in Non-small Cell Lung Cancer With c-Met Dysregulation(KUNPENG)CompletedNCT04258033Phase 2
- Pemigatinib in Treating Patients With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Including FGFR2 RearrangementCompletedNCT04256980Phase 2
- Pyrotinib in Breast Cancer Patients With Poor Response to the Neoadjuvant Treatment of Trastuzumab and PertuzumabStatus unknownNCT04255056Phase 2
- A Study of CS3007 in Subjects With Gastrointestinal Stromal TumorCompletedNCT04254939Phase 1/2
- This Phase II/III, Multicenter Study is Designed to Evaluate the Safety and Clinical Activity of AL3810 in PatientsStatus unknownNCT04254471Phase 2/3
- Clinical Study of Apatinib Combined With Temozolomide in the Treatment of Uncontrolled or Repeated High-grade GliomasStatus unknownNCT04253873Phase 2
- Pharmacokinetics (Drug Levels in Blood) of BMS-986165 When Taken as Various Solid Tablet Prototypes by Healthy ParticipantsCompletedNCT04249284Phase 1
- Capecitabine Plus Pyrotinib Versus Capecitabine Plus Trastuzumab and Pertuzumab in the First-line Treatment of HER2-positive Metastatic Breast CancerStatus unknownNCT04246502Phase 2
- Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic SarcomasCompletedNCT04242238Phase 1
- Efficacy and Safety of Lenvatinib as a Conversion Therapy for HCCStatus unknownNCT04241523Phase 2
- Itacitinib for the Treatment of Bronchiolitis Obliterans Syndrome After Donor Hematopoietic Cell TransplantTerminatedNCT04239989Phase 1