Tyrosine Kinase Inhibitors: all 10,479 studies that test it
Page 69 of 105. Open to participants first (1,915), then studies with results posted, then the rest; newest registration first within each.
- Dual PD-1 and JAK2 Inhibition in Hematological MalignanciesWithdrawnNCT04016116Phase 2
- A Clinical Study of SKLB1028 Capsule in the Treatment of Recurrence/Refractory AML PatientsStatus unknownNCT04015024Phase 2
- A Phase 1 Study of NOV1601(CHC2014) in Adult Subjects With Solid Organ MalignanciesCompletedNCT04014257Phase 1
- A Study of Tyrosine Kinase Inhibitor Orelabrutinib (ICP-022) in Patients With r/r B-Cell MalignanciesActive, not recruitingNCT04014205Phase 1/2
- SHR-1210 Plus Apatinib in Patients With Advanced-Stage Hepatocellular CarcinomaStatus unknownNCT04014101Phase 2
- Apatinib Mesylate Combined With Doxorubicin and Ifosfamide in Advanced Soft-tissue SarcomaStatus unknownNCT04012827Phase 2
- Evaluation of Risk-Adapted and MRD-Driven Strategy for Untreated Fit Patients With Intermediate Risk Chronic Lymphocytic LeukemiaCompletedNCT04010968Phase 2
- Axitinib Plus Toripalimab as Second-line Treatment in Hepatobiliary Malignant TumorsStatus unknownNCT04010071Phase 2
- Study of TQ-B3139 Versus Crizotinib in the First Line Treatment of Subjects With Anaplastic Lymphoma Kinase (ALK) Positive Non-Small Cell Lung Cancer (NSCLC)Status unknownNCT04009317Phase 3
- Regorafenib and XELOX as 2nd Line Treatment in Metastatic Colorectal CancerStatus unknownNCT04008511Phase 1/2
- Anlotinib Hydrochloride Combined With EGFR-Tyrosine Kinase Inhibitor (TKI) in Treating Advanced NSCLC Patients With Acquired Resistance to EGFR-TKIStatus unknownNCT04007835Not applicable
- PD-1 Antibody + Apatinib Mesylate in 2+ Line Serum AFP-elevated Gastric AdenocarcinomaStatus unknownNCT04006821Phase 2
- Entacapone Combination With Imatinib for Treatment of GISTCompletedNCT04006769Early Phase 1
- Brigatinib and Binimetinib in Treating Patients With Stage IIIB-IV ALK or ROS1-Rearranged Non-small Cell Lung CancerTerminatedNCT04005144Phase 1
- Clinical Study on the Treatment of Recurrent Glioblastoma With AnlotinibStatus unknownNCT04004975Phase 1/2
- Bioavailability Study of PF-06651600 Formulations in Healthy ParticipantsCompletedNCT04004663Phase 1
- A Study to Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With Bendamustine Plus Rituximab in Adults With Previously Untreated Mantle Cell Lymphoma Who Are Ineligible for Stem Cell TransplantationActive, not recruitingNCT04002297Phase 3
- Anlotinib in Metastatic HER2 Negative Breast CancerCompletedNCT04002284Phase 2
- A Study of APG-1252 Plus Osimertinib(AZD9291) in EGFR TKI Resistant NSCLC PatientsActive, not recruitingNCT04001777Phase 1
- YIV-906 (Formerly PHY906/KD018) With Sorafenib in HBV(+) Hepatocellular Carcinoma (HCC)CompletedNCT04000737Phase 2
- Apatinib and Etoposide Capsule Versus Weekly Paclitaxel in Patients With Platinum Resistant Ovarian CancerStatus unknownNCT04000295Phase 3
- Anlotinib Single Drug as the Maintenance Treatment for Advanced NSCLCStatus unknownNCT03998085Not applicable
- A Study of Pyrotinib Plus Vinorelbine in Comparison With Treatment of Physician's Choice in Participants With HER2-positive Locally Advanced or Metastatic Breast CancerStatus unknownNCT03997539Phase 2
- Study of TQB2450 Combined With Anlotinib in Subjects With Advanced CholangiocarcinomaStatus unknownNCT03996408Phase 1/2
- Genetic Testing in Guiding Treatment for Patients With Brain MetastasesActive, not recruitingNCT03994796Phase 2
- Study of Dosage Exploration and Pharmacokinetics for HA121-28 TabletsStatus unknownNCT03994484Phase 1
- Study of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in METActive, not recruitingNCT03993873Phase 1
- Study of TQB2450 Combined With Anlotinib in Subjects With Advanced Acral Malignant MelanomaStatus unknownNCT03991975Phase 1/2
- Fostamatinib in the Treatment of Chronic Active Antibody Mediated RejectionActive, not recruitingNCT03991780Phase 1/2
- Itacitinib and Alemtuzumab in Treating Patients With T-Cell Prolymphocytic LeukemiaCompletedNCT03989466Phase 1
- Apatinib Plus SHR1210 in Advanced Mucosal MelanomaStatus unknownNCT03986515Phase 2
- Study of TQB2450 Combined With Anlotinib in the Treatment of Mutation Positive Lung CancerStatus unknownNCT03983928Phase 1/2
- Effect of Rifampin and Efavirenz on the Pharmacokinetics of Fedratinib in Healthy Adult SubjectsCompletedNCT03983239Phase 1
- A Pharmacokinetics and Tolerability Study of Fedratinib in Subjects With Moderate and Severe Hepatic ImpairmentCompletedNCT03983161Phase 1
- Combination Neoadjuvant Chemotherapy With or Without Apatinib for HER2 Negative Breast CancerActive, not recruitingNCT03982485Phase 2
- A Study of Evaluating The Effects Of Pyrotinib After Adjuvant Trastuzumab In Women With Early Stage Breast CancerActive, not recruitingNCT03980054Phase 3
- A Study to Investigate the Effects of Gastric Acid Suppression by Rabeprazole and BMS-986165 on How Fast and Complete The Drug is Absorbed Into the Body of Healthy ParticipantsCompletedNCT03979248Phase 1
- Geptanolimab(GB226) Combined With Fruquintinib in the Treatment of Metastatic Colorectal CancerStatus unknownNCT03977090Phase 1
- Safety and Efficacy of Genolimzumab (GB226) in Combination With FruquintinibStatus unknownNCT03976856Phase 1
- Clinical Study on the Second-line and Above Treatment of Advanced Solid Tumor With Anlotinib Combined With Pd-1 AntibodyStatus unknownNCT03975036Phase 2/3
- Safety and Efficacy Study of TQ-B3101 in Patients With ROS1-positive Non-Small Cell Lung Cancer (NSCLC)Status unknownNCT03972189Phase 2
- A Study of Tivozanib in Combination With Durvalumab in Subjects With Advanced Hepatocellular CarcinomaTerminatedNCT03970616Phase 1/2
- Whole Genomic Landscape of Advanced EGFR-mutant NSCLCActive, not recruitingNCT03969823Not applicable
- Study of Oral Debio 0123 in Combination With Carboplatin in Participants With Advanced Solid TumorsTerminatedNCT03968653Phase 1
- Evaluation of Cabozantinib in Metastatic Renal Cell Carcinoma (mRCC) With Brain MetastasesCompletedNCT03967522Phase 2
- AXL Inhibitor BGB324 in Treating Participants With Recurrent Glioblastoma Undergoing SurgeryTerminatedNCT03965494Early Phase 1
- A Study to Assess the Relative Bioavailability of Gilteritinib Following a Single Dose of Gilteritinib Mini-tablet Oral Suspension and Gilteritinib Mini-tablets Compared to a Single Dose of Gilteritinib Tablet in Healthy SubjectsCompletedNCT03964038Phase 1
- Cabozantinib toLERANCE Study in HepatoCellular Carcinoma (CLERANCE)CompletedNCT03963206Phase 4
- Effect of Multiple Doses of Modafinil on the Pharmacokinetics of Single Dose Lorlatinib in Healthy ParticipantsCompletedNCT03961997Phase 1
- Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCLActive, not recruitingNCT03960840Phase 1/2
- Single and Multiple Dose Pharmacokinetics of BMS-986165 in a Randomized, Double-Blind, Placebo-Controlled Study in Healthy Chinese SubjectsCompletedNCT03956953Phase 1
- PD-1 Antibody SHR-1210 Combined With Apatinib of First-line Treatment of Advanced Acral MelanomaStatus unknownNCT03955354Phase 2
- Efficacy of Nintedanib Per os as a Treatment for Epistaxis in HHT Disease.CompletedNCT03954782Phase 2
- Exploratory Clinical Study of Apatinib and PD-1 in Treating Advanced Gastric CancerStatus unknownNCT03954756Phase 2
- A Dose Escalation Study Evaluating CPI-818 in Relapsed/Refractory T-Cell LymphomaActive, not recruitingNCT03952078Phase 1
- The Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMPL-523 in Immune Thrombocytopenia PatientsCompletedNCT03951623Phase 1
- Efficacy and Safety of Anlotinib in Adjuvant Therapy for High-grade Soft Tissue SarcomaCompletedNCT03951571Phase 2
- Lenvatinib and Everolimus in Treating Patients With Advanced, Unresectable Carcinoid TumorsActive, not recruitingNCT03950609Phase 2
- Apatinib Combined With S-1 as Maintenance Therapy for HER-2 Negatived Gastric CancerStatus unknownNCT03950141Phase 2
- Study Evaluating the Safety and Efficacy of iR2 in Untreated and Unfit Elderly Patients With DLBCLStatus unknownNCT03949062Phase 2
- Neoadjuvant Study of Pyrotinib and Trastuzumab Plus Vinorelbine in Trastuzumab-refractory HER2-Positive Breast Cancer.Status unknownNCT03947242Not applicable
- Study of Anlotinib Hydrochloride and Toripalimab in Subjects With Unresectable or Metastatic Undifferentiated Pleomorphic SarcomaStatus unknownNCT03946943Phase 2
- JS001 Combined With Regorafenib in Patients With Advanced Colorectal CancerStatus unknownNCT03946917Phase 1/2
- Venetoclax and Acalabrutinib in Treating Patients With Relapsed or Refractory Mantle Cell LymphomaActive, not recruitingNCT03946878Phase 2
- A Multicenter Study of Anlotinib in Hepatocellular Carcinoma (HCC) Patients at High Risk of Post Surgery RecurrenceTerminatedNCT03945799Phase 1/2
- Efficacy of Baricitinib In Treatment of Delayed-Type Hypersensitivity Versus Irritant Skin Reactions in Healthy Adult Male SubjectsCompletedNCT03945760Early Phase 1
- A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With Apatinib and Fluzoparib in Patients With TNBCCompletedNCT03945604Phase 1
- Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)Active, not recruitingNCT03944772Phase 2
- Cabozantinib in Patients With Advanced Penile Squamous Cell Carcinoma (PSCC) (CaboPen)Status unknownNCT03943602Phase 2
- Ibrutinib and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia After Ibrutinib ResistanceWithdrawnNCT03943342Phase 2
- Nilotinib for First-line Newly Diagnosed CML-CP PatientsStatus unknownNCT03942094Phase 3
- Apatinib With Albumin-bound Paclitaxel in Patients With Platinum-resistant Recurrent Ovarian CancerStatus unknownNCT03942068Phase 2
- Study Evaluating the Mass Balance And Biotransformation of Single Dose[14C] AST2818 in Chinese Healthy Male VolunteersCompletedNCT03941340Phase 1
- Afatinib in Previously Treated ESCC With EGFR Overexpression or EGFR Amplification (ESCC-A01)Status unknownNCT03940976Phase 2
- Management of Progressive Disease in Idiopathic Pulmonary FibrosisCompletedNCT03939520Phase 4
- Abexinostat and Ibrutinib in Diffuse Large B-cell Lymphoma and Mantle Cell LymphomaCompletedNCT03939182Phase 1
- Effect of Meal Composition and Timing on Evobrutinib BioavailabilityCompletedNCT03934502Phase 1
- A Study of Pyrotinib Plus Vinorelbine in Patients With Brain Metastases From HER2-positive Metastatic Breast CancerStatus unknownNCT03933982Phase 2
- Effect of Nilotinib in Cerebellar Ataxia PatientsCompletedNCT03932669Phase 2
- Combined Use of Apatinib Mesylate and Vinorelbine Versus Single Use of Vinorelbine in Triple-negative Breast CancerStatus unknownNCT03932526Phase 2
- Study to Characterize the Effects of Cytochrome p450 1A2 Inhibition on Systemic Exposure to BMS-986165CompletedNCT03930602Phase 1
- Anlotinib in Advanced Solid Tumors With FGFR AlterationStatus unknownNCT03929965Not applicable
- Study to Characterize Absorption, Distribution, Metabolism and Excretion of 14C PF-06651600 and to Evaluate the Absolute Oral Bioavailability and Fraction Absorbed of PF-06651600.CompletedNCT03929510Phase 1
- Clinical Study of Inhaled GB002 for Treatment of WHO Group I Pulmonary Arterial HypertensionCompletedNCT03926793Phase 1
- Study to Determine the Effect of Food on the Blood Levels of AST2818 Following Single Oral Doses in Healthy Male VolunteersCompletedNCT03926182Phase 1
- Anlotinib for Patients With Platinum Resistant or Refractory Ovarian CancerStatus unknownNCT03924882Phase 2
- Phase II Clinical Study of Pyrotinib Combined With Etoposide to Treat HER2-positive Advanced Breast CancerStatus unknownNCT03923179Phase 2
- Pyrotinib Combined With Capecitabine Metronomic Therapy in HER2-postitive Advanced Breast CancerStatus unknownNCT03923166Phase 2
- A Maximum Use Trial of Ruxolitinib Cream in Adolescent and Adult Participants With Atopic DermatitisCompletedNCT03920852Phase 1
- Phase II of Lenvatinib Plus Toripalimab for Advanced HCCWithdrawnNCT03919383Phase 2
- Neratinib + Valproate in Advanced Solid Tumors, w/Expansion Cohort in Ras-Mutated CaSuspendedNCT03919292Phase 1/2
- Pyrotinib in Combination With Nab-paclitaxel in Patients With HER2-positive Advanced Breast Cancer: an Exploratory StudyStatus unknownNCT03919253Phase 2
- Single Dose and Multiple Dose Study to Assess Safety and Tolerability of LOU064CompletedNCT03918980Phase 1
- The Phase II Trial of SHR-1210 Combined With Preoperative Chemotherapy or Apatinib for Locally Advanced ESCCStatus unknownNCT03917966Phase 2
- PF-06651600 Taste Study.CompletedNCT03916393Phase 1
- Evaluation of Skin Irritation Potential With PF-06700841 Cream Formulation Using Negative Control in Adult Japanese Healthy ParticipantsCompletedNCT03916250Phase 1
- A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk TumorsCompletedNCT03914794Phase 2
- A Safety, Tolerability, and Pharmacokinetic Study of Tucatinib in Healthy Japanese and Caucasian SubjectsCompletedNCT03914755Phase 1
- Apatinib in the Treatment of Recurrence or Metastasis of Esophageal CancerStatus unknownNCT03913182Phase 2
- CABozantinib in Non-Small Cell Lung Cancer (NSCLC) Patients With MET DeregulationStatus unknownNCT03911193Phase 2