Drug
Tinengotinib clinical trials
Also written TT-00420.
- studies test it
- 9
- open now
- 4
- in phase 3
- 2
- first study started
- 2019
Keep track of what changes. Save the tinengotinib studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Combined with it in one product
Studies by the year they started
9 studies that test it; most in 2026 (3)
| Year | Studies |
|---|---|
| 2019 | 1 |
| 2020 | 1 |
| 2021 | 1 |
| 2023 | 2 |
| 2024 | 1 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 3
- Phase 2
- 5
- Phase 3
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 8 · Other 1
TransThera Sciences (Nanjing), Inc. (8) · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School (1)
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses tinengotinib is read from its arms, and is right about nine times in ten.
Testing it · 9
- Safety, Efficacy and Pharmacokinetics of TT00420 Tablets Combined With Novel Endocrine Therapy in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC)RecruitingPhase 2TransThera Sciences (Nanjing), Inc.NCT07871110Written as tinengotinib 10 mg QD plus darolutamide
- Efficacy and Safety of Tinengotinib Tablets Combined With Fulvestrant Injection in Patients With HR Positive and HER-2 Negative Recurrent or Metastatic Breast Cancer Who Have Failed Prior TreatmentRecruitingPhase 2TransThera Sciences (Nanjing), Inc.NCT07498478Written as Tinengotinib
- Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or MutationsNot yet recruitingPhase 3TransThera Sciences (Nanjing), Inc.NCT07328919Written as TT-00420 (tinengotinib)
- Safety and Efficacy of TT-00420 Tablets Combined With Toripalimab Injection in Advanced Urological TumorsNot yet recruitingPhase 1/2The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolNCT06221774Written as TT-00420 + Toripalimab
- Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in CholangiocarcinomaActive, not recruitingPhase 3TransThera Sciences (Nanjing), Inc.NCT05948475Written as Tinengotinib 8 mg
- Study of TT-00420 (Tinengotinib) in Subjects With Cholangiocarcinoma Who Failed or Relapsed to Chemotherapy and FGFR InhibitorActive, not recruitingPhase 2TransThera Sciences (Nanjing), Inc.NCT06057571Written as TT-00420 (tinengotinib)
- Safety of TT-00420 (Tinengotinib) Monotherapy in Patients With Advanced Solid Tumors and Triple Negative Breast CancerCompletedPhase 1TransThera Sciences (Nanjing), Inc.NCT03654547Written as TT-00420
- Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in CholangiocarcinomaCompletedPhase 2TransThera Sciences (Nanjing), Inc.NCT04919642Written as TT-00420
- Relative Bioavailability Study and Food Effect Study of TT-00420 (Tinengotinib) Capsule and Tablet Formulations in Healthy VolunteersCompletedPhase 1TransThera Sciences (Nanjing), Inc.NCT04705922Written as TT-00420 Capsule
Given in every arm · 4 — tinengotinib is usual care beside what is tested
- A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate CancerRecruitingPhase 1/2Memorial Sloan Kettering Cancer CenterNCT06457919Written as Tinengotinib
- A Phase II Clinical Study of AK104/AK112 in Combination With TT-00420 Tablet for Advanced HCC.RecruitingPhase 2AkesoNCT07052253Written as TT-00420 (tinengotinib)
- To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid TumorsCompletedPhase 1/2TransThera Sciences (Nanjing), Inc.NCT05253053Written as TT-00420
- Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid TumorsCompletedPhase 1/2TransThera Sciences (Nanjing), Inc.NCT04742959Written as TT-00420
Codes
What other systems call tinengotinib · ClinicalTrials.gg INT018403
- UNII (FDA) WZ9TJ0L9Y8TINENGOTINIBOne source FDA
- NCI Thesaurus C162532TinengotinibOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| UNII (FDA) | WZ9TJ0L9Y8 | TINENGOTINIB | One source FDA |
| NCI Thesaurus | C162532 | Tinengotinib | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.