Drug
Tetrahydrouridine clinical trials
Keep track of what changes. Save the Tetrahydrouridine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
12 studies that test it; most in 2017 (2)
| Year | Studies |
|---|---|
| 1999 | 1 |
| 2004 | 1 |
| 2007 | 1 |
| 2009 | 1 |
| 2011 | 1 |
| 2012 | 1 |
| 2016 | 1 |
| 2017 | 2 |
| 2018 | 1 |
| 2023 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 1 · Other 11
Yogen Saunthararajah (3) · City of Hope Medical Center (2) · National Cancer Institute (NCI) (2) · EpiDestiny, Inc. (1) · Case Comprehensive Cancer Center (1) · University of Miami (1) · Brian Lally (1) · Clinical Hub for Interventional Research (CHOIR) (1)
Often tested with
Tested in the same studies.
Decitabine (7) · 5-fluoro-2'-deoxycytidine (2) · Cytochlor (2) · Cisplatin (1) · Pembrolizumab (1) · Fluorine F 18 5-Fluoro-2-deoxycytidine (1)
Studies
Open first, then newest update. How each study uses Tetrahydrouridine is read from its arms, and is right about nine times in ten.
Testing it · 12
- Modulation of Stem Cell Differentiation in Individuals With High Risk Clonal HaematopoiesisNot yet recruitingPhase 2Clinical Hub for Interventional Research (CHOIR)NCT07435636Written as Oral Decitabine and Tetrahydrouridine
- 5-Fluoro-2'-Deoxycytidine and Tetrahydrouridine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic SyndromesCompletedPhase 1City of Hope Medical CenterNCT01041443Written as tetrahydrouridine
- To Study the Oral Bioavailability of a New Combination Formation of Decitabine and Tetrahydrouridine in Healthy MalesCompletedPhase 1EpiDestiny, Inc.NCT05816356Written as Tetrahydrouridine
- Rational EpigenetiC Immunotherapy for SEcond Line Therapy in Patients With NSCLC: PRECISE TrialCompletedPhase 2Case Comprehensive Cancer CenterNCT02664181Written as Tetrahydrouridine
- Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal CarcinomasTerminatedPhase 1/2National Cancer Institute (NCI)NCT03233724Written as Tetrahydrouridine (THU)
- Imaging Study for FdCyd and THU Cancer TreatmentTerminatedEarly Phase 1National Cancer Institute (NCI)NCT01479348Written as Tetrahydrouridine intravenous (IV)
- p53/p16-Independent Epigenetic Therapy With Oral Decitabine/Tetrahydrouridine for Pancreatic CancerCompletedEarly Phase 1Yogen SaunthararajahNCT02847000Written as Tetrahydrouridine
- p53/p16-Independent Epigenetic Therapy With Oral Decitabine/Tetrahydrouridine for Refractory/Relapsed Lymphoid MalignanciesCompletedEarly Phase 1Yogen SaunthararajahNCT02846935Written as Tetrahydrouridine
- Study of Decitabine and Tetrahydrouridine (THU) in Patients With Sickle Cell DiseaseCompletedPhase 1Yogen SaunthararajahNCT01685515Written as Oral Decitabine and Tetrahydrouridine
- Cytochlor and Tetrahydrouridine as Radiosensitizers and Cisplatin Combined With Radiation Therapy in Treating Patients With Advanced Squamous Cell Carcinoma of the Oral Cavity (Mouth) or Oropharynx (Throat)CompletedPhase 1University of MiamiNCT00077051Written as tetrahydrouridine
- 5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced CancerCompletedPhase 1City of Hope Medical CenterNCT00359606Written as Tetrahydrouridine (THU)
- Cytochlor, Tetrahydrouridine, and External-Beam Radiation Therapy in Treating Patients With Cancer That Has Spread to the BrainCompletedPhase 1Brian LallyNCT00521183Written as Tetrahydrouridine
Given in every arm · 1 — Tetrahydrouridine is usual care beside what is tested
Codes
What other systems call Tetrahydrouridine · ClinicalTrials.gg INT008297
- MeSH (NLM) D013767TetrahydrouridineConfirmed ClinicalTrials.gov, Wikidata
- UNII (FDA) 0NIZ8H6OL8TETRAHYDROURIDINEConfirmed FDA, Wikidata
- Wikidata Q27237004tetrahydrouridineConfirmed FDA, Wikidata
- NCI Thesaurus C868TetrahydrouridineOne source FDA
- DrugBank DB12484One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D013767 | Tetrahydrouridine | Confirmed ClinicalTrials.gov, Wikidata |
| UNII (FDA) | 0NIZ8H6OL8 | TETRAHYDROURIDINE | Confirmed FDA, Wikidata |
| Wikidata | Q27237004 | tetrahydrouridine | Confirmed FDA, Wikidata |
| NCI Thesaurus | C868 | Tetrahydrouridine | One source FDA |
| DrugBank | DB12484 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.