Temozolomide: all 659 studies that test it

Page 3 of 7. Open to participants first (91), then studies with results posted, then the rest; newest registration first within each.

• HSPPC-96 Vaccine With Temozolomide in Patients With Newly Diagnosed GBMCompletedNCT00905060Phase 2Results posted
• Genetic Variates of Response to Cisplatin, Vinblastine, and Temozolomide (CVT) in Patients With Metastatic MelanomaCompletedNCT00885534Phase 2Results posted
• Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) TumorsCompletedNCT00876993Phase 1Results posted
• Capecitabine and Temozolomide for Neuroendocrine CancersCompletedNCT00869050Phase 2Results posted
• Medical Treatment of "High-Risk" NeurofibromasCompletedNCT00846430Phase 2Results posted
• Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic AstrocytomaCompletedNCT00841555Phase 1Results posted
• Dose-Dense Temozolomide + Lapatinib for Recurrent EpendymomaCompletedNCT00826241Phase 2Results posted
• RT, Temozolomide, and Bevacizumab Followed by Bevacizumab/Everolimus in First-line Treatment of GBMCompletedNCT00805961Phase 2Results posted
• MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic GliomaTerminatedNCT00756106Not applicableResults posted
• Temozolomide for Relapsed Sensitive or Refractory Small Cell Lung CancerCompletedNCT00740636Phase 2Results posted
• Vorinostat, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00731731Phase 1/2Results posted
• BIBW 2992 (Afatinib) With or Without Daily Temozolomide in the Treatment of Patients With Recurrent Malignant GliomaCompletedNCT00727506Phase 2Results posted
• Study of Temozolomide to Treat Newly Diagnosed Brain MetastasesTerminatedNCT00717275Phase 2Results posted
• Combination of Decitabine and Temozolomide in the Treatment of Patients With Metastatic MelanomaCompletedNCT00715793Phase 1/2Results posted
• Study of Temozolomide in Previously Untreated Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Participants With Low O6-Methylguanine Methyltransferase (MGMT) Expression (P05052)CompletedNCT00687323Phase 2Results posted
• Standard Temodal (Temozolomide) Regimen Versus Standard Regimen Plus Early Postsurgery Temodal for Newly Diagnosed Glioblastoma Multiforme (Study P05572)CompletedNCT00686725Phase 4Results posted
• Temozolomide Phase II Clinical Study in Patients With Newly Diagnosed Glioblastoma Multiforme (Study P04661)(COMPLETED)CompletedNCT00684567Phase 2Results posted
• Pilot Trial of "Chemo-Switch" Regimen to Treat Advanced MelanomaTerminatedNCT00673361Phase 2Results posted
• Study of Temzolomide and Gleevec in Advanced MelanomaTerminatedNCT00667953Phase 1/2Results posted
• Dose-Intense Temozolomide in Recurrent GlioblastomaCompletedNCT00657267Phase 2Results posted
• Vaccine Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00643097Phase 2Results posted
• Temozolomide as a Prophylaxis Against Brain Recurrence in Participants With Metastatic Breast Cancer (P05225 AM2)TerminatedNCT00638963Phase 2Results posted
• Study of Maintenance Temozolomide Versus Observation in Stable or Responding Stage III/IV Non-Small Cell Lung Cancer Patients (Study P05146)TerminatedNCT00632203Phase 2Results posted
• Phase I Dose-Escalation Study Of Azacitidine In Combination With TemozolomideCompletedNCT00629343Phase 1Results posted
• Phase III Trial of Anaplastic Glioma Without 1p/19q Loss of Heterozygosity (LOH)Active, not recruitingNCT00626990Phase 3Results posted
• Bevacizumab and Temozolomide or Bevacizumab and Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed by SurgeryCompletedNCT00626405Phase 2Results posted
• Temozolomide in Treating Patients With Recurrent High-Grade GliomaCompletedNCT00619112Phase 2Results posted
• Irinotecan and Temozolomide in Treating Patients With Breast Cancer Who Have Received Previous Treatment for Brain MetastasesCompletedNCT00617539Phase 2Results posted
• Ph II Bev + Either Temozolomide/Etoposide for GBM Pts Who Have Failed Bev + IrinotecanCompletedNCT00613028Phase 2Results posted
• Avastin in Combination With Temozolomide for Unresectable or Multifocal GBMs and GliosarcomasCompletedNCT00612339Phase 2Results posted
• Phase 2 Study of Temozolomide to Treat Poor Risk / Refractory Acute Myeloid LeukemiaCompletedNCT00611247Phase 2Results posted
• Temozolomide and Sorafenib in Treating Patients With Metastatic or Unresectable MelanomaCompletedNCT00602576Phase 2Results posted
• Ph. 2 Sorafenib + Protracted Temozolomide in Recurrent GBMCompletedNCT00597493Phase 2Results posted
• Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and GliosarcomasCompletedNCT00597402Phase 2Results posted
• Phase II Trial of Extended-Dosing Temozolomide in Patients With MelanomaCompletedNCT00591370Phase 2Results posted
• Bevacizumab and Temozolomide Following Radiation and Chemotherapy for Newly Diagnosed Glioblastoma MultiformeCompletedNCT00590681Phase 2Results posted
• Phase II Trial of Neoadjuvant Temozolomide in Melanoma Patients With Palpable Stage III or IV Disease Undergoing Complete Surgical ResectionCompletedNCT00588341Phase 2Results posted
• Phase II Study of Gamma Knife Radiosurgery and Temozolomide for Brain MetastasesCompletedNCT00582075Phase 2Results posted
• RAD001 and Temozolomide in Patients With Advanced Pancreatic Neuroendocrine TumorsCompletedNCT00576680Phase 1/2Results posted
• Efficacy of Protracted Temozolomide in Patients With Progressive High Grade GliomaCompletedNCT00575887Phase 2Results posted
• Paclitaxel and Carboplatin or Temozolomide in Treating Patients With Stage IV MelanomaTerminatedNCT00568451Phase 2Results posted
• Vorinostat, Isotretinoin and Temozolomide in Adults With Recurrent Glioblastoma Multiforme (GBM)TerminatedNCT00555399Phase 1/2Results posted
• Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed GlioblastomaCompletedNCT00553150Phase 1/2Results posted
• Radiation Therapy and Temozolomide Followed by Temozolomide Plus Sorafenib for Glioblastoma MultiformeCompletedNCT00544817Phase 2Results posted
• Temozolomide,Thiotepa and Carboplatin With Autologous Stem Cell Rescue Followed by 13-cis-retinoic Acid in Patients With Recurrent/Refractory Malignant Brain TumorsCompletedNCT00528437Phase 2Results posted
• Temozolomide and Everolimus in Treating Patients With Stage IV Melanoma That Cannot be Removed by SurgeryCompletedNCT00521001Phase 2Results posted
• Bortezomib and Temozolomide in Treating Patients With Advanced Refractory Solid Tumors or MelanomaTerminatedNCT00512798Phase 1/2Results posted
• Biochemotherapy With Temozolomide for Metastatic MelanomaTerminatedNCT00505635Phase 2Results posted
• 6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma PatientsCompletedNCT00504660Phase 2Results posted
• Bevacizumab in Combination With Metronomic Temozolomide for Recurrent Malignant GliomaCompletedNCT00501891Phase 2Results posted
• Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant GliomaCompletedNCT00498927Phase 2Results posted
• Hydroxychloroquine, Radiation, and Temozolomide Treating Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00486603Phase 1/2Results posted
• Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00482677Phase 3Results posted
• O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation TherapyTerminatedNCT00436436Phase 2Results posted
• Bevacizumab and Irinotecan or Temozolomide in Treating Patients With Recurrent or Refractory Glioblastoma Multiforme or GliosarcomaCompletedNCT00433381Phase 2Results posted
• Low-dose Temozolomide for 2 Weeks on Brain Tumor Enzyme in Patients With Gliomas (P04602 AM1) (Completed)CompletedNCT00424554Phase 2Results posted
• Phase 2 Study of Temozolomide in Pre-Selected Advanced Aerodigestive Tract Cancers (Study P04273AM2)(TERMINATED)TerminatedNCT00423150Phase 2Results posted
• Combination of Irinotecan and Temozolomide in Children With Brain Tumors.CompletedNCT00404495Phase 2Results posted
• Phase 1/2 Study of Enzastaurin in Newly Diagnosed Glioblastoma Multiforme (GBM) and Gliosarcoma (GS) PatientsCompletedNCT00402116Phase 1/2Results posted
• The Effects of Continuous 28-day (28/28) Temozolomide Chemotherapy in Subjects With Recurrent Malignant Glioma Who Have Failed the Conventional 5-day (5/28) Treatment (P04601)CompletedNCT00392171Phase 2Results posted
• Carboplatin and Temozolomide (Temodar) for Recurrent and Symptomatic Residual Brain MetastasesCompletedNCT00362817Phase 1/2Results posted
• Temozolomide in Treating Patients With Low-Grade GliomaCompletedNCT00313729Phase 2Results posted
• Irinotecan and Temozolomide in Treating Young Patients With Recurrent NeuroblastomaCompletedNCT00311584Phase 2Results posted
• Motexafin Gadolinium, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or GliosarcomaCompletedNCT00305864Phase 1/2Results posted
• Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain TumorsCompletedNCT00302159Phase 2Results posted
• Phase I/II Study of High-Dose Calcitriol Plus Temodar for Patients With Metastatic MelanomaCompletedNCT00301067Phase 1/2Results posted
• O6-Benzylguanine and Temozolomide in Treating Young Patients With Recurrent or Progressive Gliomas or Brain Stem TumorsCompletedNCT00275002Phase 2Results posted
• Safety and Tolerability of Low-Dose Temozolomide During Whole Brain Radiation in Patients With Cerebral Metastases From Non-Small-Cell Lung Cancer (Study P04071)(TERMINATED)TerminatedNCT00266812Phase 2Results posted
• Radiation Therapy and Temozolomide Followed by Temozolomide and Poly ICLC in Treating Patients With Newly Diagnosed GBMCompletedNCT00262730Phase 2Results posted
• Rituximab, Temozolomide, and Methylprednisolone in Treating Patients With Recurrent Primary CNS Non-Hodgkin's LymphomaTerminatedNCT00248534Phase 2Results posted
• Temozolomide & RT Followed by Dose Dense vs Temozolomide & Retinoic Acid in Pts w/GlioblastomaCompletedNCT00200161Phase 2Results posted
• Safety and Efficacy Study of Tarceva, Temodar, and Radiation Therapy in Patients With Newly Diagnosed Brain TumorsCompletedNCT00187486Phase 2Results posted
• Temozolomide and Radiation Therapy in Treating Patients With GliomasCompletedNCT00114140Phase 2Results posted
• Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed GliomasCompletedNCT00100802Phase 2Results posted
• Thalidomide and Temozolomide in Relapsed or Progressive CNS Disease or NeuroblastomaCompletedNCT00098865Phase 2Results posted
• Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung CancerTerminatedNCT00096265Phase 3Results posted
• Temozolomide Versus Dacarbazine in Stage IV Metastatic Melanoma (Study P03267)CompletedNCT00091572Phase 3Results posted
• Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00085254Phase 1/2Results posted
• Chemotherapy Combined With Radiation Therapy for Newly Diagnosed CNS AT/RTCompletedNCT00084838Phase 2Results posted
• Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung CancerCompletedNCT00080938Phase 2Results posted
• Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade GliomaCompletedNCT00077207Not applicableResults posted
• Combination Chemotherapy, Monoclonal Antibody, and Radiation Therapy in Treating Patients With Primary Central Nervous System LymphomaCompletedNCT00068250Phase 1/2Results posted
• Phase I/II Evaluation of Temozolomide and ZARNESTRA (R115777) for Recurrent and Progressive Glioblastoma MultiformeCompletedNCT00050986Phase 1/2Results posted
• Temozolomide and Vinorelbine in Treating Patients With Recurrent Brain MetastasesCompletedNCT00026494Phase 1/2Results posted
• Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed GliomasCompletedNCT00004259Phase 3Results posted
• Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral ChemotherapyCompletedNCT06625047Phase 4
• Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant GliomaActive, not recruitingNCT06478212Phase 1/2
• Regorafenib With Temozolomide With or Without RT in MGMT-Methylated, IDH Wild-type GBM PatientsCompletedNCT06095375Phase 1
• The Efficacy and Safety of Temozolomide in Patients With MPPGLCompletedNCT05858177Phase 2
• HTMC0435 and Temozolomide in Treating Patients With Small Cell Lung CancerStatus unknownNCT05728619Phase 1/2
• Neoadjuvant Chemoimmunotherapy in Recurrent GlioblastomaStatus unknownNCT05700955Phase 1
• LITT Combined With Early Use of Temozolomide for Recurrent GlioblastomasStatus unknownNCT05663125Phase 1/2
• Safety and Efficacy of TRPP Therapy in Glioblastoma MultiformeStatus unknownNCT05589961Early Phase 1
• Surgical Pembro +/- Olaparib w TMZ for rGBMActive, not recruitingNCT05463848Phase 2
• Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid TumorsTerminatedNCT05429502Phase 1
• Comparing Capecitabine and Temozolomide in Combination to Lutetium Lu 177 Dotatate in Patients With Advanced Pancreatic Neuroendocrine Tumors, the ComPareNET TrialActive, not recruitingNCT05247905Phase 2
• Temozolomide and Irinotecan in Patients With MGMT Silenced Colorectal Cancer After Adjuvant ChemotherapyStatus unknownNCT05031975Phase 2
• Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Neuroblastoma: A Single-arm, Phase I/II，Multi-center, Clinical Study.CompletedNCT05027386Phase 1/2
• Temozolomide + Nivolumab in MGMT Methylated Oesophagogastric CancerCompletedNCT04984733Phase 2
• Ph I/II Study of NMS-03305293+TMZ in Adult Patients With Recurrent GlioblastomaActive, not recruitingNCT04910022Phase 1/2

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