Temozolomide: all 659 studies that test it
Page 1 of 7. Open to participants first (91), then studies with results posted, then the rest; newest registration first within each.
- Metronomic Temozolomide With Dexbrompheniramine for Recurrent High-Grade Glioma/GlioblastomaNot yet recruitingNCT07859059Phase 1/2
- Trial of Temozolomide in BAP1 Mutated Patients With Advanced or Metastatic Cutaneous MelanomaNot yet recruitingNCT07807878Phase 2
- Trial of NLG802 Indoximod Prodrug Plus Temozolomide for Patients With Progressive Pediatric Brain CancerNot yet recruitingNCT07732413Phase 1
- Temozolomide, With or Without WSD0922-FU, for the Treatment of EGFR-Mutant, IDH-Wildtype GlioblastomaRecruitingNCT07708961Phase 2
- Intensified Adjuvant Therapy for High-Risk Newly Diagnosed Glioblastoma With Subtotal Resection or Short-Term ProgressionRecruitingNCT07670026Phase 2
- A Prospective, Single-arm Clinical Study on the Safety and Efficacy of Ivoximab Combined With Temozolomide in the Treatment of Relapsed/Refractory GliomaRecruitingNCT07599371Phase 1/2
- A Rollover Study of NBM-BMX in Combination With Temozolomide in Patients With Newly Diagnosed GlioblastomaRecruitingNCT07569042Phase 1/2
- Focused Ultrasound Blood-Brain Barrier Opening in Pontine Diffuse Midline Glioma to Enhance Temozolomide Therapy: Pilot Feasibility Study (FIDES)Not yet recruitingNCT07562971Phase 1/2
- Integrating Biology for Safe Intensification of Glioblastoma Hypofractionated Treatment on the MR-LinacNot yet recruitingNCT07457307Phase 1
- 5G-PEARL: Paxalisib in Malignant Brain TumoursRecruitingNCT07391215Phase 1/2
- Chemoimmunotherapy Combined With Autologous NK Cell Therapy for Pediatric Patients With Refractory and Relapsed High-Risk Neuroblastoma and GanglioneuroblastomaRecruitingNCT07375563Phase 3
- Neoantigen-Pulsed Autologous Dendritic Cell Vaccine Combined With Temozolomide for Newly Diagnosed GlioblastomaNot yet recruitingNCT07365280Phase 2
- Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual DiseaseRecruitingNCT07346157Phase 1/2
- A Clinical Trial Testing the Safety of the Investigational Drug Pumitamig (BNT327) and How Well it Works in Patients With Recurrent GlioblastomaRecruitingNCT07297212Phase 2
- Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System TumorsRecruitingNCT07243470Phase 1/2
- Metastatic Ewing's Trial Testing Schedule Enhancement to Improve OutcomesRecruitingNCT07194044Phase 1
- A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma（SELINA）RecruitingNCT07191431Not applicable
- Sintilimab in Combination With Surufatinib and Temozolomide in the Advanced Neuroendocrine CarcinomaNot yet recruitingNCT07156019Phase 2
- An Umbrella Study of Recurrent, Extensive Stage Small Cell Lung Cancer Based on Molecular TypingNot yet recruitingNCT07141771Phase 1/2
- A Study to Evaluate the Safety and Efficacy of L19TNF With Alkylating Chemotherapy for Patients With Recurrent IDH-mutant Astrocytoma or OligodendrogliomaNot yet recruitingNCT07120984Phase 2
- A Phase II Clinical Study to Evaluate the Efficacy and Safety of Flazoparib Combined With Temozolomide After the Completion of Standard Concurrent Chemoradiotherapy (CCRT) in Newly Diagnosed GlioblastomaNot yet recruitingNCT07047066Phase 2
- Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory NeuroblastomaRecruitingNCT07027748Phase 1
- Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual DiseaseRecruitingNCT07025226Early Phase 1
- Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory NeuroblastomaRecruitingNCT06995872Phase 1
- Study of ABBV-637 or ABBV-155 With ERAS-801 for People With GlioblastomaRecruitingNCT06934889Phase 1
- Embryonal Tumor With Multilayered RosettesRecruitingNCT06861244Phase 2
- Phase II Study of Irinotecan Liposome (II) Combined With Temozolomide and Fluzoparib in Recurrent or Metastatic Ewing SarcomaRecruitingNCT06827717Phase 2
- Vebreltinib Combined With Temozolomide for Glioblastoma (GBM) After SurgeryNot yet recruitingNCT06780592Phase 2
- Precision Medicine Trial Based on Molecular Matching Therapy for Patients With Standard Treatment ExhaustionRecruitingNCT06739395Phase 2
- PEEL-224, Vincristine and Temozolomide in Pediatric Solid TumorsRecruitingNCT06721689Phase 1/2
- Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory SarcomasRecruitingNCT06709495Phase 1/2
- A Phase 2 Study of HX301 in Patients with High-grade GilomaRecruitingNCT06703255Phase 1/2
- Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLCRecruitingNCT06681220Phase 1/2
- 5G-RUBY: Avutometinib and Defactinib in Malignant Brain TumoursRecruitingNCT06630260Phase 1/2
- Study of Senaparib in Combination With Temozolomide in ARID1A Mutation Associated Ovarian CancerRecruitingNCT06617923Phase 2
- JK-1201I Combined with Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma Multiforme (GBM)RecruitingNCT06595186Phase 2
- A Study of Selinexor in Combination With Temozolomide and Anti-PD-1 Antibody in Patients With Relapsed/Refractory Primary Central Nervous System LymphomaRecruitingNCT06556199Phase 1/2
- N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With NeuroblastomaRecruitingNCT06528496Phase 2
- DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade GliomaRecruitingNCT06504381Phase 1/2
- The Sagittarius TrialRecruitingNCT06490536Phase 3
- NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) TrialRecruitingNCT06450041Phase 2
- STARLITE for Unresectable High-Grade GliomasRecruitingNCT06428045Phase 1
- TTField in Combination With Temozolomide and Tislelizumab in The Treatment of Newly Diagnosed Glioblastoma.RecruitingNCT06353360Phase 2
- Evaluate the Role of Anthracycline After Radio Therapy in Patients With Glioblastoma (pGBM).RecruitingNCT06297512Phase 2
- Niraparib and Temozolomide in Patients GlioblastomaNot yet recruitingNCT06258018Phase 1/2
- Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent CancerRecruitingNCT06208657Phase 1/2
- Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine CarcinomasNot yet recruitingNCT06202066Phase 2
- Cisplatin Plus Temozolomide Compared With Temozolomide in Patients With MGMT Promotor Unmethylated GlioblastomaNot yet recruitingNCT06186440Phase 1/2
- Study of Olutasidenib and Temozolomide in HGGRecruitingNCT06161974Phase 2
- NBM-BMX Administered Orally to Patients With Solid Tumors or Newly Diagnosed GlioblastomaRecruitingNCT06012695Phase 1/2
- A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With CancerRecruitingNCT05999994Phase 2
- A Study on the Safety and Effectiveness of Temozolomide for Neoadjuvant Treatment of PPGLRecruitingNCT05885386Phase 2
- Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutantRecruitingNCT05843253Phase 2
- Camrelizumab in Combination With Apatinib and Temozolomide as First-line Treatment in Advanced Acral MelanomaRecruitingNCT05789043Phase 3
- A Study to Evaluate Safety and Efficacy of BEY1107 in Combination with Temozolomide in Patients with Recurrent or Progressive Glioblastoma Multiforme (GBM)RecruitingNCT05769660Phase 1
- A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent GliomaRecruitingNCT05698524Phase 1
- Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and EffectivenessRecruitingNCT05691491Phase 1/2
- The Efficacy and Safety of Temozolomide in SDH-deficient GISTRecruitingNCT05661643Phase 2
- Sintilimab in Combination With Bevacizumab and Temozolomide in Recurrent Glioblastoma (GBM) PatientsRecruitingNCT05638451Phase 2
- A Phase III Study of Postoperative Early Temozolomide Treatment Plus STUPP Regimen for Newly Diagnosed GBM MultiformeRecruitingNCT05600491Phase 3
- Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the BrainRecruitingNCT05588453Phase 1/2
- Metronomic Temozolomide in Unfit NENs Patients Metronomic Temozolomide in Unfit Patients With Advanced Neuroendocrine Neoplasms (NENs): MeTe StudyRecruitingNCT05554003Phase 2
- Metronomic Chemotherapy in Wilms Tumor (MetroWilms-1906)RecruitingNCT05384821Phase 1/2
- Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal CancerRecruitingNCT05136326Phase 2
- To Explore the Efficacy and Safety of SHR-1701 Combined With Temozolomide in the Treatment of Advanced MelanomaRecruitingNCT05106023Phase 2
- Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With GlioblastomaRecruitingNCT05083754Phase 1
- hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM)RecruitingNCT05052957Phase 2
- Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine TumorsRecruitingNCT05040360Phase 2
- Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma TrialRecruitingNCT05030298Phase 1
- Orelabrutinib, Sintilimab and Temozolomide in Relapsed or Refractory Central Nervous System LymphomaRecruitingNCT04961515Phase 2
- Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy TemozolomideRecruitingNCT04945148Phase 2
- Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung CancerRecruitingNCT04919382Phase 2
- Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing SarcomaRecruitingNCT04901702Phase 1/2
- A Trial Evaluating the Activity and Safety of Combination Between Cabozantinib and Temozolomide in Lung and GEP-NENS Progressive After Everolimus, Sunitinib or PRRT (CABOTEM)RecruitingNCT04893785Phase 2
- Rituximab, Lenalidomide Combined With Methotrexate and Temozolomide For Primary Central Nervous System LymphomaRecruitingNCT04737889Phase 2
- 5FU/LV, Irinotecan, Temozolomide and Bevacizumab for MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer.RecruitingNCT04689347Phase 1/2
- Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) GlioblastomasRecruitingNCT04623931Phase 2
- Vaccination With Autologous Dendritic Cells Loaded With Autologous Tumour Homogenate in GlioblastomaRecruitingNCT04523688Phase 2
- Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed GlioblastomaRecruitingNCT04443010Phase 1/2
- CapTemY90 for Grade 2/3 NET Liver MetastasesRecruitingNCT04339036Phase 2
- Radiotherapy Versus Radiotherapy Combined With Temozolomide in High-risk Low-grade Gliomas After SurgeryRecruitingNCT04316039Phase 2/3
- Study of Recombinant Human Endostatin Combined with Temozolomide and Irinotecan in Recurrent GliomasRecruitingNCT04267978Phase 2
- High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)RecruitingNCT04221035Phase 3
- Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent SarcomaRecruitingNCT04199026Not applicable
- Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBMRecruitingNCT03213002Phase 1/2
- INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)RecruitingNCT02977780Phase 2
- European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory TumorsRecruitingNCT02813135Phase 1/2
- Effect of Cytokine-induced Killer Cells for Advanced Malignant GliomasNot yet recruitingNCT02496988Phase 4
- Effect of Cytokine-induced Killer Cells for Stage I-II Malignant GliomasNot yet recruitingNCT02494804Phase 1/2
- Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade GliomaRecruitingNCT01649830Phase 3
- Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS TumorsRecruitingNCT01356290Phase 2
- Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped WorkingActive, not recruitingNCT05432791Phase 2/3Results posted
- Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral MicrodialysisActive, not recruitingNCT05413304Phase 1Results posted
- Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers, RARE 2 TrialActive, not recruitingNCT05142241Phase 2Results posted
- A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in GlioblastomaActive, not recruitingNCT04900792Phase 1Results posted
- A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent GlioblastomaTerminatedNCT04421378Phase 1/2Results posted
- Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL)Active, not recruitingNCT04385277Phase 2Results posted
- Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed GlioblastomaActive, not recruitingNCT04216329Phase 1Results posted
- Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue SarcomaActive, not recruitingNCT04200443Phase 2Results posted
- TMZ + Olaparib for MGMT Hypermethylated Colorectal CancerCompletedNCT04166435Phase 2Results posted