Sugammadex: all 201 studies that test it

Page 1 of 3. Open to participants first (15), then studies with results posted, then the rest; newest registration first within each.

• Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECTRecruitingNCT07534475Not applicable
• A Dose-response Study to Determine the Right Dosage of Sugammadex as a Reversal Agent of Rocuronium in Infants Between 1 and 24 Months OldNot yet recruitingNCT07477132Phase 4
• Impact of Sugammadex Versus Neostigmine on Early Postoperative Pulmonary FunctionRecruitingNCT07309393Not applicable
• Neuromuscular Blocking Agents on Gastrointestinal Function Following Colorectal SurgeryNot yet recruitingNCT07271875Phase 3
• Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney DiseaseRecruitingNCT07203287Phase 4
• Sugammadex-Induced Clenching During Neuromuscular Blockade ReversalRecruitingNCT06962007Not applicable
• Recovery Times of Half Dose Sugammadex and Neostigmine for Rocuronium-induced Neuromuscular BlockadeRecruitingNCT06794450Phase 1/2
• Sugammadex on Laparoscopic Bariatric SurgeryNot yet recruitingNCT06678451Not applicable
• Placental Transfer of Sugammadex in the Human Placental Perfusion ModelEnrolling by invitationNCT06634355Not applicable
• Sugammadex Dose Finding Under Two Years OldNot yet recruitingNCT06575036Phase 2
• Deep Versus Moderate Neuromuscular Blockade in Bariatric SurgeryNot yet recruitingNCT06553066Not applicable
• The Clinical Effect of Sugammadex Sodium (Domestic) for Antagonizing Neuromuscular Blockade After Thoracic SurgeryRecruitingNCT06334562Not applicable
• Effects of Sugammadex and Conventional Reversal on Lung Function in Laparoscopic Abdominal SurgeryRecruitingNCT06210165Not applicable
• Pharmacological Reversal of Neuromuscular Blockade in Critically Ill PatientsRecruitingNCT05993390Not applicable
• Effectiveness on Smooth Extubation According to the Administration Time of SugammadexNot yet recruitingNCT05751603Not applicable
• Muscle Relaxation for Pediatric AdenotonsillectomyCompletedNCT06225466Phase 4Results posted
• Neuromuscular Blockade Comparison for GI-2 Recovery After Bowel ResectionCompletedNCT06112353Phase 4Results posted
• Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine SurgeryCompletedNCT05887375Phase 4Results posted
• Evaluating Outcomes in Cardiac Surgery Patients Who Receive Sugammadex vs. PlaceboCompletedNCT05801679Phase 3Results posted
• Postoperative Urinary Retention After Reversal of Neuromuscular Block by Neostigmine Versus SugammadexCompletedNCT05794503Phase 4Results posted
• Sugammadex as Rescue TherapyCompletedNCT05661409Phase 4Results posted
• Postoperative Urinary Retention in Patients After Noncardiac Surgery and Reversal of Neuromuscular BlockCompletedNCT05545280Phase 4Results posted
• The POUR (Postoperative Urinary Retention) StudyCompletedNCT05276804Phase 3Results posted
• Sugammadex vs Neostigmine Reversal in Pediatric AppendectomyTerminatedNCT05256901Phase 4Results posted
• Comparison of Time to Extubation Using Sugammadex or NeostigmineCompletedNCT04606901Phase 4Results posted
• Optimizing Post-operative Recovery in Bariatric Patients With Obstructive Sleep Apnea Undergoing Outpatient Surgery: A Comparison of Sugammadex and NeostigmineCompletedNCT04570150Phase 4Results posted
• Sugammadex To IMprove Bowel FunctionCompletedNCT04546672Phase 4Results posted
• Applying Best Clinical Practices to Patients at High Risk of Respiratory ComplicationsCompletedNCT04263363Phase 4Results posted
• Pharmacokinetic-pharmacodynamic Analysis of Sugammadex in ChildrenCompletedNCT03943888Phase 2Results posted
• Role of Sugammadex as Reversal Agent in Patients Extubated Immediately After Isolated Coronary Artery Bypass Grafting SurgeryCompletedNCT03939923Phase 4Results posted
• Sugammadex Versus Neostigmine for Reversal of Neuromuscular Blockade at the End of Kidney Transplantation SurgeryCompletedNCT03923556Phase 4Results posted
• Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 Years (MK-8616-169)CompletedNCT03909165Phase 4Results posted
• Neuromuscular Blockade in Patients With Severe Renal ImpairmentCompletedNCT03904550Phase 2Results posted
• Impact of Sugammadex vs. Neostigmine Reversal on Post-Operative Recovery and ComplicationsCompletedNCT03679611Phase 4Results posted
• Efficacy and Safety of Org 25969 Administered After Zemuron® (MK-8616-042)CompletedNCT03519867Phase 2Results posted
• Efficacy, Safety and Pharmacokinetics of Sugammadex (Org 25969; MK-8616) at 3 Different Time Points After 0.6 mg/kg Esmeron® in Male Participants (P05940; MK-8616-020).CompletedNCT03519854Phase 2Results posted
• Efficacy, Safety, and Pharmacokinetics of Sugammadex for Reversal of Neuromuscular Blockade (NMB) in Pediatric Participants (MK-8616-089)CompletedNCT03351608Phase 4Results posted
• Efficacy and Safety of Sugammadex Dosed According to Actual Body Weight (ABW) or Ideal Body Weight (IBW) in Reversal of Neuromuscular Blockade (NMB) in Morbidly Obese Participants (MK-8616-146)CompletedNCT03346070Phase 4Results posted
• Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145)CompletedNCT03346057Phase 4Results posted
• Sugammadex Versus Neostigmine for Reversal of Rocuronium NeuromuscularCompletedNCT03322657Phase 4Results posted
• A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy SurgeryTerminatedNCT03276026Phase 4Results posted
• Effect of Sugammadex vs. Neostigmine/Glycopyrrolate on Pediatric Emergence Delirium in Sevoflurane-rocuronium AnesthesiaCompletedNCT03229486Phase 4Results posted
• Neuromuscular Blockade on Shoulder Pain of ElderlyCompletedNCT03210376Phase 4Results posted
• Compare the Oncological Benefit of Deep Neuromuscular Block in Gastric Cancer Obesity PatientCompletedNCT03196791Phase 3Results posted
• Sugammadex and Decreased Time to ExtubationCompletedNCT03196167Phase 4Results posted
• Sugammadex vs. Neostigmine for Neuromuscular Blockade Reversal in Thoracic Surgical PatientsCompletedNCT03168308Phase 4Results posted
• Investigation of Sugammadex in Outpatient Urological ProceduresCompletedNCT03138967Phase 4Results posted
• Speed of Recovery of Reversal of Neuromuscular Blockade in Geriatric Patients Undergoing Spine SurgeryCompletedNCT03112993Phase 4Results posted
• Use of Sugammadex for Reversal of Paralysis in MicrolaryngoscopyCompletedNCT03111121Phase 4Results posted
• A Randomized Controlled Crossover Study Comparing Sugammadex and PlaceboCompletedNCT03087513Phase 4Results posted
• Neuromuscular Blockade During Transurethral Resection of Bladder CancerCompletedNCT03039543Phase 4Results posted
• Deep Neuromuscular Block for Laparoscopic SurgeryCompletedNCT03034577Phase 4Results posted
• Quality of Recovery After Reversal With Neostigmine or Sugammadex.CompletedNCT02909439Phase 4Results posted
• The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary ComplicationsCompletedNCT02861131Phase 4Results posted
• Study to Determine if Administration of Sugammadex Impacts Hospital EfficiencyCompletedNCT02860507Phase 4Results posted
• Effect of Neuromuscular Blockade and Reversal on BreathingCompletedNCT02845375Phase 4Results posted
• Sugammadex vs Placebo to Prevent Residual Neuromuscular BlockCompletedNCT02728726Phase 4Results posted
• The Effect of Deep Neuromuscular Block on Surgical Condition During Laparoscopic Colorectal SurgeryCompletedNCT02580188Phase 4Results posted
• Can Adequacy of Anesthesia Depth and Quality of Recovery be Influenced by the Level of Neuromuscular Blockade?CompletedNCT02484651Phase 4Results posted
• Effectiveness of Sugammadex in LMS SurgeryStatus unknownNCT02329964Phase 4Results posted
• Optimizing Surgical Conditions During Laparoscopic Herniotomy With Deep Neuromuscular BlockadeCompletedNCT02247466Phase 4Results posted
• Effect of Neuromuscular Reversal With Sugammadex on Postoperative Recovery ProfileCompletedNCT02243943Phase 4Results posted
• The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical ProstatectomyCompletedNCT02109133Not applicableResults posted
• The Effect of Deep Block Versus Moderate Block on the Stress Response After Laparoscopic GastrectomyCompletedNCT02100280Phase 4Results posted
• A Study to Evaluate the Incidence of Hypersensitivity After Administration of Sugammadex in Healthy Participants (MK-8616-101)CompletedNCT02028065Phase 1Results posted
• Pharmacokinetics of Sugammadex (MK-8616) in Participants With Moderate and Severe Renal Insufficiency (MK-8616-105)CompletedNCT02011490Phase 1Results posted
• Influence of Mild Hypothermia on Reversal of Rocuronium With SugammadexCompletedNCT01965067Phase 4Results posted
• Recovery of Diaphragmatic Function After Neuromuscular Blockade and SugammadexCompletedNCT01962298Phase 3Results posted
• Optimizing Surgical Conditions During Gynecologic Laparoscopic Surgery With Deep Neuromuscular BlockadeCompletedNCT01933425Phase 4Results posted
• A Study Comparing the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures in Participants Undergoing Laparoscopic Cholecystectomy (P07982)CompletedNCT01728584Phase 4Results posted
• Study of Sugammadex Versus Usual Care on Incidence of Residual Blockade at Post Anesthesia Care Unit Admission (P07981)CompletedNCT01479764Phase 3Results posted
• Reversal of Neuromuscular Blockade With Sugammadex or Usual Care in Hip Fracture Surgery or Joint (Hip/Knee) Replacement (P07038)CompletedNCT01422304Phase 3Results posted
• Comparison of Sugammadex With Neostigmine as Reversal Agents for Rocuronium at Reappearance of T2 (Study P06101)CompletedNCT01050543Phase 3Results posted
• Sugammadex Hypersensitivity Study (Study P06042)CompletedNCT00988065Phase 1Results posted
• Efficacy and Safety of 4.0 mg/kg Sugammadex at 1-2 PTC in Chinese and European Subjects (Study 19.4.335)(P05775AM1)(COMPLETED)CompletedNCT00826176Phase 3Results posted
• Comparison of 2.0 mg/kg Sugammadex and Neostigmine at Reappearance of T2 in Chinese and European Subjects (Study 19.4.324)(P05768AM1)(COMPLETED)CompletedNCT00825812Phase 3Results posted
• Comparing 4.0 mg.Kg-1 Sugammadex With Placebo in the Reversal of Profound Neuromuscular Blockade (P05767)CompletedNCT00758485Phase 3Results posted
• Rocuronium Plus Sugammadex Versus Succinylcholine Alone in Participants Undergoing Short Surgical Procedures (19.4.319)(P05700 AM2)(COMPLETED)CompletedNCT00751179Phase 3Results posted
• Comparison of Sugammadex With Neostigmine During Laparoscopic Cholecystectomy or Appendectomy (P05699)CompletedNCT00724932Phase 3Results posted
• Comparison of 4.0 mg/kg Sugammadex at 1-2 Post Tetanic Counts (PTC) in Renal or Control Patients (19.4.328)(P05769)CompletedNCT00702715Phase 3Results posted
• Comparison of Sugammadex Administered at 1-2 Post Tetanic Counts (PTCs) or Better With Neostigmine Administered as Per Standard of Care to Reverse Rocuronium-Induced Neuromuscular Blockade in Adults Undergoing Elective Open Abdominal Procedure (19.4.334) (P05774)CompletedNCT00675792Phase 3Results posted
• Dialysis of Sugammadex in Participants With Severe Renal Impairment (Study 19.4.333) (P05773)CompletedNCT00656799Phase 3Results posted
• A Bridging Trial Comparing Sugammadex (Org 25969) at 1-2 Post-Tetanic Count (PTC) in Japanese Participants. Part A (P05957)CompletedNCT00591786Phase 2Results posted
• A Bridging Trial Comparing Sugammadex (Org 25969) at Reappearance of T2 in Japanese and Caucasian Participants. Part A: Japanese Participants (P05956)CompletedNCT00591409Phase 2Results posted
• A Bridging Trial Comparing Sugammadex (Org 25969) at 1-2 Post-Tetanic Count (PTC) in Caucasian Participants. Part B (P05974)CompletedNCT00552929Phase 2Results posted
• A Bridging Trial Comparing Sugammadex (Org 25969) at Reappearance of T2 in Japanese and Caucasian Participants. Part B: Caucasian Participants (P05971)CompletedNCT00552617Phase 2Results posted
• Dose-Finding Trial With Sugammadex Administered at 3 and 15 Minutes After 1.0 and 1.2 mg/kg Rocuronium Bromide in Participants of ASA Class 1-3 (P05944; MK-8616-024)CompletedNCT00535743Phase 2Results posted
• Relation Between TOF-Watch® SX and a Peripheral Nerve Stimulator After 4.0 mg.Kg-1 Sugammadex (P05698)CompletedNCT00535496Phase 3Results posted
• Safety and Efficacy of Sugammadex (Org 25969, MK-8616) in Participants With or Having a Past History of Pulmonary Disease (19.4.308) (P05932) (MK-8616-017)CompletedNCT00475215Phase 3Results posted
• Comparison of the Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616; Org 25969) in Elderly Participants With Adult Participants (MK-8616-029)CompletedNCT00474617Phase 3Results posted
• Comparison of Recovery From Rocuronium 1.2 mg/kg Followed by Sugammadex (Org 25969) 16 mg/kg at 3 Minutes With Recovery From Succinylcholine 1.0 mg/kg (19.4.303)(P05946)(MK-8616-026)CompletedNCT00474253Phase 3Results posted
• Comparison of Sugammadex (MK-8616/Org 25969) With Neostigmine Administered at 1-2 Post-tetanic Counts (PTCs) After Administration of Rocuronium or Vecuronium (19.4.302/P05945/MK-8616-025)CompletedNCT00473694Phase 3Results posted
• Comparison of Sugammadex (Org 25969) With Neostigmine as Reversal Agents for Rocuronium or Vecuronium at Reappearance of T2 (P05960)CompletedNCT00451217Phase 3Results posted
• Dose-Finding Pediatric and Adult Trial With Sugammadex (Org 25969, MK-8616, SCH 900616) (19.4.306) (MK-8616-034) (P05961)CompletedNCT00421148Phase 3Results posted
• Use of Sugammadex at the End of Case in Routine Anesthesia (MK-8616-023)CompletedNCT00298831Phase 3Results posted
• The Effect of Neostigmine and Sugammadex on the Optic Nerve Sheath DiameterCompletedNCT07666984Phase 4
• Using Diaphragm Ultrasonography, Sugammadex Recovers Diaphragmatic Function More Effectively Than Neostigmine.CompletedNCT06982092Phase 1
• Efficacy and Safety of Sugammadex in Thoracoscopy Thymectomy for Chinese Adults With Myasthenia GravisCompletedNCT06436768Not applicable
• Sugammadex v.s. Neostigmine/GlycopyrrolateCompletedNCT06398899Not applicable
• Neostigmine/Glyco-pyrrolate 50 Mikrogram/kg or Sugammadex 2 mg/kg for Reversal of Neuromuscular Blockade in Elderly PatientsCompletedNCT06228092Phase 4

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