Sitagliptin: all 313 studies that test it

Page 2 of 4. Open to participants first (12), then studies with results posted, then the rest; newest registration first within each.

• The CANTATA-M (CANagliflozin Treatment and Trial Analysis - Monotherapy) TrialCompletedNCT01081834Phase 3Results posted
• Safety and Efficacy of Co-Administration of Sitagliptin and Metformin in China (MK-0431-121)CompletedNCT01076088Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of Sitagliptin 100 mg in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (MK-0431-229)CompletedNCT01076075Phase 3Results posted
• Comparison of NN1250 With Sitagliptin in Subjects With Type 2 Diabetes Never Treated With InsulinCompletedNCT01046110Phase 3Results posted
• A Local Experiential Study With Sitagliptin (an Antihyperglycemic Drug) in 30 Patients With Type 2 Diabetes Mellitus (0431-178)CompletedNCT01034111Phase 3Results posted
• 30-Week Extension to an Initial Combination Study (24 Weeks in Duration) of Sitagliptin With Pioglitazone (0431-064)CompletedNCT01028391Phase 3Results posted
• DPP-4 Inhibition and TZD for DM PreventionTerminatedNCT01006018Not applicableResults posted
• Efficacy and Safety of Sitagliptin/Metformin Fixed-Dose Combination (FDC) Compared to Glimepiride in Participants With Type 2 Diabetes Mellitus (MK-0431A-202)CompletedNCT00993187Phase 4Results posted
• Prevention of Cystic Fibrosis DiabetesTerminatedNCT00967798Phase 3Results posted
• Dipeptidyl Peptidase-4 Inhibition on Glucagon-like Peptide-1 (GLP-1)TerminatedNCT00947011Phase 2Results posted
• Using Sitagliptin as a Treatment to Prevent New Onset Diabetes After Kidney TransplantationTerminatedNCT00936663Phase 4Results posted
• Sitagliptin/Metformin Fed Bioequivalence Study (0431A-080)CompletedNCT00929201Phase 1Results posted
• A Method to Evaluate Glucose-Dependent Insulin Secretion in Healthy Males (MK-0431-179)CompletedNCT00888238Phase 1Results posted
• Effects of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Hormonal Responses to Macronutrient IngestionCompletedNCT00885638Phase 4Results posted
• Sitagliptin (MK-0431) vs. Placebo in Patients With Inadequate Glycemic Control on Metformin With Pioglitazone (MK-0431-128)CompletedNCT00885352Phase 3Results posted
• Study to Assess the Efficacy and Safety of Sitagliptin Added to the Regimen of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (0431-189)CompletedNCT00875394Phase 3Results posted
• A Comparison of Adding Exenatide With Switching to Exenatide in Patients With Type 2 Diabetes Experiencing Inadequate Glycemic Control With Sitagliptin Plus MetforminCompletedNCT00870194Phase 4Results posted
• Sitagliptin Umbilical Cord Blood Transplant StudyCompletedNCT00862719Phase 2Results posted
• Evaluation of Insulin Glargine in Combination With Sitagliptin in Type 2 Diabetes Patients: EASIE Extension TrialCompletedNCT00851903Phase 3Results posted
• Novel Therapy to Preserve Beta Cell Function in New Onset Type 1 DiabetesTerminatedNCT00837759Phase 2Results posted
• MK0431/ONO-5435 Phase III Clinical Trial -Add-on to Voglibose Study for Patients With Type 2 Diabetes Mellitus (MK0431-104)CompletedNCT00837577Phase 3Results posted
• ALPHA Sitagliptin Add on to Metformin (0431-103)CompletedNCT00833027Phase 4Results posted
• The Effect of Sitagliptin in Type 2 Diabetes Mellitus With Inadequate Glycemic Control (MK0431-118)TerminatedNCT00832624Phase 4Results posted
• Study to Assess the Efficacy and Safety of Sitagliptin in Recently Diagnosed, Naive Type 2 Diabetics With Inadequate Glycemic Control on Diet and Exercise (0431-158)CompletedNCT00832390Phase 4Results posted
• A Study of the Effects of Co-Administration of Sitagliptin (MK-0431) and Metformin on Incretin Hormone Concentrations (MK-0431-110)CompletedNCT00830076Phase 1Results posted
• Mechanisms of Glucose Lowering Effects of Sitagliptin and Metformin Alone and in Combination in Patients With T2DMCompletedNCT00820573Phase 4Results posted
• A Study to Test the Safety and Efficacy of Adding Sitagliptin in Patients With Type 2 Diabetes Mellitus (MK0431-074)CompletedNCT00813995Phase 3Results posted
• Incretin Effect in People With Impaired Fasting GlucoseCompletedNCT00795275Not applicableResults posted
• Sitagliptin Cardiovascular Outcomes Study (MK-0431-082)CompletedNCT00790205Phase 3Results posted
• Effect of Exenatide, Sitagliptin or Glimepiride on Functional ß -Cell MassCompletedNCT00775684Not applicableResults posted
• Incretin Effect and Use After Clinical Islet TransplantationCompletedNCT00768651Phase 2Results posted
• Clinical Study on Sitagliptin for Assessment of Glucose-lowering Effects (0431-045)CompletedNCT00758069Phase 2Results posted
• BI 10773 add-on to Metformin in Patients With Type 2 DiabetesCompletedNCT00749190Phase 2Results posted
• A Study to Assess the Pharmacokinetics, Safety and Tolerability of Sitagliptin in Adolescents (0431-081)CompletedNCT00730275Phase 1Results posted
• Comparison of the Effect of Exenatide Versus Sitagliptin on 24-hour Average Glucose in Patients With Type 2 Diabetes on Metformin or a ThiazolidinedioneCompletedNCT00729326Phase 4Results posted
• MK0431 and Pioglitazone Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-102 AM2)CompletedNCT00722371Phase 3Results posted
• Sitagliptin Mechanism of Action Study in Patients With Type 2 Diabetes Mellitus (0431-059)CompletedNCT00704132Phase 1Results posted
• A Study to Test the Safety and Efficacy of Sitagliptin Compared to Glimepiride in Patients With Type 2 Diabetes on a Stable Dose of Metformin (0431-803)(COMPLETED)CompletedNCT00701090Phase 3Results posted
• The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes MellitusCompletedNCT00700817Phase 3Results posted
• Sitagliptin in Combination With Metformin and SulfonylureaCompletedNCT00686634Phase 4Results posted
• Effects of Glutamine on GLP-1 and Insulin Secretion in ManCompletedNCT00673894Not applicableResults posted
• Effects of Sitagliptin on Postprandial Lipemia in Men With Type 2 DiabetesCompletedNCT00660075Phase 3Results posted
• The Effect of Januvia (Sitagliptin) on Oxidative Stress in Obese Type 2 Diabetic SubjectsCompletedNCT00659711Not applicableResults posted
• Study of the Effect of Sitagliptin on Glucose (Sugar) Metabolism in Patients With Heart FailureCompletedNCT00657280Early Phase 1Results posted
• A Study to Test the Effectiveness and Safety of MK0893 in Combination With Other Drugs Used to Treat Type 2 Diabetes (0893-015)CompletedNCT00631488Phase 2Results posted
• Safety/Efficacy of Sitagliptin in Patient w/ Type 2 Diabetes (0431-801)CompletedNCT00541775Phase 3Results posted
• A Study to Evaluate the Efficacy and Safety of Sitagliptin and MK0431A in Comparison to a Commonly Used Medication in Patients With Type 2 Diabetes (0431-068)(COMPLETED)CompletedNCT00541450Phase 3Results posted
• Sitagliptin Dose Comparison Study in Patients With Type 2 Diabetes (MK-0431-077)(COMPLETED)CompletedNCT00541229Phase 1Results posted
• MK0431A vs. Pioglitazone in Patients With Type 2 Diabetes Mellitus (0431A-066)CompletedNCT00532935Phase 3Results posted
• Sitagliptin and Pioglitazone Mechanism of Action Study in Type 2 Diabetes Mellitus (0431-061)CompletedNCT00511108Phase 1Results posted
• Sitagliptin Versus Glipizide in Participants With Type 2 Diabetes Mellitus and Chronic Renal Insufficiency (MK-0431-063 AM1)CompletedNCT00509262Phase 3Results posted
• Sitagliptin Versus Glipizide in Participants With Type 2 Diabetes Mellitus and End-Stage Renal Disease (MK-0431-073 AM1)CompletedNCT00509236Phase 3Results posted
• MK0431A Comparative Study in Patients With Type 2 Diabetes (0431A-079)(COMPLETED)CompletedNCT00482729Phase 3Results posted
• Sitagliptin Comparative Study in Patients With Type 2 Diabetes (0431-049)CompletedNCT00449930Phase 3Results posted
• Beta-Cell Function and Sitagliptin Trial (BEST)CompletedNCT00420511Phase 2Results posted
• A Study of Sitagliptin in Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Diet/Exercise Therapy (0431-054)(COMPLETED)CompletedNCT00411554Phase 3Results posted
• Long Term Effects of DPP-IV Inhibitor Treatment in Patients With Type 2 DiabetesCompletedNCT00411411Phase 3Results posted
• Initial Combination With Pioglitazone Study (0431-064)CompletedNCT00397631Phase 3Results posted
• Sitagliptin Added-on to Insulin Study (0431-051)CompletedNCT00395343Phase 3Results posted
• MK0431 (Sitagliptin) Pioglitazone Add-on Study for Patients With Type 2 Diabetes Mellitus (0431-055)(COMPLETED)CompletedNCT00372060Phase 3Results posted
• Incretins in Impaired Fasting GlucoseCompletedNCT00364377Phase 4Results posted
• Sitagliptin Metformin/PPARg Agonist Combination Therapy Add-on (0431-052)CompletedNCT00350779Phase 3Results posted
• Sitagliptin Metformin Add-on Study in Patients With Type 2 Diabetes MellitusCompletedNCT00337610Phase 3Results posted
• Study of Sitagliptin in Older Type 2 Diabetics (0431-047)(COMPLETED)CompletedNCT00305604Phase 3Results posted
• MK0431 Monotherapy Study in Patients With Type 2 Diabetes Mellitus (0431-040)CompletedNCT00289848Phase 3Results posted
• A Study of an Investigational Drug Sitagliptin for Type 2 Diabetes Mellitus (0431-044)CompletedNCT00127192Phase 2Results posted
• Sulfonylurea Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-035)CompletedNCT00106704Phase 3Results posted
• MK0431 (Sitagliptin) and Metformin Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-036)CompletedNCT00103857Phase 3Results posted
• An Investigational Drug in Patients With Type 2 Diabetes Mellitus and Chronic Renal Insufficiency (0431-028)(COMPLETED)CompletedNCT00095056Phase 3Results posted
• An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (0431-024)CompletedNCT00094770Phase 3Results posted
• An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (MK0431-023)CompletedNCT00094757Phase 3Results posted
• Monotherapy Study in Patients With Type 2 Diabetes Mellitus (0431-021)CompletedNCT00087516Phase 3Results posted
• Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-020)(COMPLETED)CompletedNCT00086515Phase 3Results posted
• Pioglitazone Add-on Study in Patients With Type 2 Diabetes MellitusCompletedNCT00086502Phase 3Results posted
• Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fed Study.CompletedNCT07763964Not applicable
• Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fast Study.CompletedNCT07763951Not applicable
• Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 50 mg/1000 mg in Healthy Subjects, Fed Study.CompletedNCT07763912Not applicable
• Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 50 mg/1000 mg in Healthy Subjects, Fast Study.CompletedNCT07763899Not applicable
• Bioequivalence Study of Sitagliptin/Metformin Extended-Release Tablets in Healthy SubjectsCompletedNCT07679711Phase 1
• A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.CompletedNCT07567781Phase 1
• Dose Optimization of Sitagliptin and Duloxetine in Diabetic CirrhosisCompletedNCT07439536Phase 4
• The Effect of Sitagliptin, Pioglitazone and Dapagliflozine on Myocardial Infarction in Diabetic RatsCompletedNCT07083232Phase 4
• Effect of Sitagliptin and Empagliflozin in Combination With Metformin on Hs-CRP Levels in Patients With Type 2 Diabetes MellitusCompletedNCT06952231Phase 3
• Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.CompletedNCT06851962Phase 4
• DPP4-Inhibitors and Bone Metabolism in DiabetesCompletedNCT06770894Phase 3
• Comparative Study of Sitagliptin and Gliclazide With Metformin in Type 2 Diabetes Patients With GlucotoxicityCompletedNCT06613750Phase 4
• Effect of Sitagliptin on Polycystic Ovarian Syndrome PatientsCompletedNCT05972928Phase 2/3
• High-Dose Post-Transplant Cyclophosphamide, Bortezomib, and Sitagliptin for the Prevention of GVHDWithdrawnNCT05895201Phase 1/2
• SITAgliptin Plus GLARgine to Glycemic Control in the Hospital Setting (SITAGLAR-H)CompletedNCT05579119Phase 4
• Non-alcoholic Fatty Liver Disease and Its TreatmentCompletedNCT05480007Not applicable
• A Pharmacokinetic Study of DW6012 (FDC of Dapagliflozin and Sitagliptin) in Healthy Adult VolunteersCompletedNCT05403281Phase 1
• Which is Better to Start With DPP-4 Inhibitors or SGLT-2 Inhibitors in Egyptian Diabetic Patients?CompletedNCT05359341Not applicable
• The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune ThrombocytopeniaStatus unknownNCT05353673Phase 2
• Phase 1 Bioequivalence Study of Dapagliflozin/Sitagliptin FDC vs Loose Combination of Single ComponentsCompletedNCT05266404Phase 1
• Monitoring Parameters Beyond Glycemic Control: Impact of Sitagliptin on Quality of Life in Type 2 Diabetes PatientsCompletedNCT05167513Phase 4
• Effect of Dapagliflozin vs Sitagliptin on Liver Fat Accumulation and Body Composition in Patients With Diabetes Mellitus and Liver TransplantationCompletedNCT05042505Not applicable
• Comparison of the FGM Profiles in Patients of Type 2 Diabetes Treated With Sitagliptin and AcarboseCompletedNCT05035849Not applicable
• Safety and Efficacy of Antidiabetic Drugs in Recently Diagnosed Patients With Type 2 DiabetesCompletedNCT04916093Phase 4
• Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese SubjectsCompletedNCT04877106Phase 1
• Sitagliptin for the Treatment of Grade 3-4 and Refractory Acute Graft-versus-host DiseaseStatus unknownNCT04448587Phase 2

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