SGN-LIV1A clinical trials
Also written SGN-LIV1A and ladiratuzumab vedotin.
How each study uses SGN-LIV1A has had a first review. Readers can ask us to read every study one by one.Ask us to read each study
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
5 studies that test it; most in 2018 (2)
| Year | Studies |
|---|---|
| 2010 | 1 |
| 2013 | 1 |
| 2018 | 2 |
| 2019 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 4 · Other 1
Seagen Inc. (3) · Hoffmann-La Roche (1) · QuantumLeap Healthcare Collaborative (1)
Often tested with
Tested in the same studies.
Ipatasertib (1) · Bevacizumab (1) · Selicrelumab (1) · Tocilizumab (1) · Albumin-Bound Paclitaxel (1) · Paclitaxel (1) · Sacituzumab govitecan (1) · Inavolisib (1)
Studies
Open first, then newest update. How each study uses SGN-LIV1A has had a first review, but it may not be perfect: check the study record before relying on it for anything important, and report a problem from its row. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 5
- A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast CancerRecruitingPhase 1/2Hoffmann-La RocheNCT03424005Written as SGN-LIV1AReport a problem
- I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast CancerRecruitingPhase 2QuantumLeap Healthcare CollaborativeNCT01042379Written as SGN-LIV1AReport a problem
- Safety and Efficacy of SGN-LIV1A Plus Pembrolizumab for Patients With Locally-Advanced or Metastatic Triple-Negative Breast CancerCompletedPhase 1/2Seagen Inc.NCT03310957Written as ladiratuzumab vedotinReport a problem
- A Study of Ladiratuzumab Vedotin in Advanced Solid TumorsTerminatedPhase 2Seagen Inc.NCT04032704Written as ladiratuzumab vedotinReport a problem
- A Safety Study of SGN-LIV1A in Breast Cancer PatientsCompletedPhase 1Seagen Inc.NCT01969643Written as ladiratuzumab vedotinReport a problem
Tested with established drugs · 3 — they are given beside it
- Safety and Efficacy of SGN-LIV1A Plus Pembrolizumab for Patients With Locally-Advanced or Metastatic Triple-Negative Breast CancerCompletedPhase 1/2Seagen Inc.NCT03310957Written as ladiratuzumab vedotinReport a problem
- A Study of Ladiratuzumab Vedotin in Advanced Solid TumorsTerminatedPhase 2Seagen Inc.NCT04032704Written as ladiratuzumab vedotinReport a problem
- A Safety Study of SGN-LIV1A in Breast Cancer PatientsCompletedPhase 1Seagen Inc.NCT01969643Written as ladiratuzumab vedotinReport a problem
Tested in a combination · 2 — another drug in the study is under test too
- A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast CancerRecruitingPhase 1/2Hoffmann-La RocheNCT03424005Written as SGN-LIV1AReport a problem
- I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast CancerRecruitingPhase 2QuantumLeap Healthcare CollaborativeNCT01042379Written as SGN-LIV1AReport a problem
Observed · 1 — patients on it are followed, or it is given outside a trial
Codes
What other systems call SGN-LIV1A · ClinicalTrials.gg INT000287
- MeSH (NLM) C000600157SGN-LIV1AOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000600157 | SGN-LIV1A | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.