Protein Kinase Inhibitors: all 15,278 studies that test it

Page 62 of 153. Open to participants first (2,556), then studies with results posted, then the rest; newest registration first within each.

• Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic LeukemiaActive, not recruitingNCT00792948Phase 2Results posted
• Comparison of Nexavar/Placebo as Maintenance Therapy for Patients With Advanced Ovarian or Primary Peritoneal CancerCompletedNCT00791778Phase 2Results posted
• Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)CompletedNCT00790400Phase 3Results posted
• Phase III Study of RAD001 Adjuvant Therapy in Poor Risk Patients With Diffuse Large B-Cell Lymphoma (DLBCL) of RAD001 Versus Matching Placebo After Patients Have Achieved Complete Response With First-line Rituximab-chemotherapyCompletedNCT00790036Phase 3Results posted
• Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)CompletedNCT00789828Phase 3Results posted
• Nilotinib in TKI Resistant or Intolerant Patients With Metastatic Mucosal, Acral, or Chronically Sun Damaged MelanomaCompletedNCT00788775Phase 2Results posted
• Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid TumorsTerminatedNCT00788125Phase 1/2Results posted
• Sunitinib Malate and Capecitabine in Treating Patients With Unresectable or Metastatic Liver CancerTerminatedNCT00787787Phase 2Results posted
• Phase II Study of Dasatinib in Previously Treated Patients With Advanced NSCLCTerminatedNCT00787267Phase 2Results posted
• A Study To Investigate The Safety And Efficacy Of CP- 690,550 In Patients With Moderate And Severe Ulcerative Colitis.CompletedNCT00787202Phase 2Results posted
• A Study of Nilotinib Versus Imatinib in GIST PatientsCompletedNCT00785785Phase 3Results posted
• A Prospective, Randomized, Placebo and Active Comparator Controlled Study of CP-690,550 in Subjects With Dry Eye.CompletedNCT00784719Phase 1/2Results posted
• Evaluating the Safety and Efficacy of Oral Lenvatinib in Medullary and Iodine-131 Refractory, Unresectable Differentiated Thyroid Cancers, Stratified by HistologyCompletedNCT00784303Phase 2Results posted
• Nilotinib in Advanced Gastrointestinal Stromal Tumors (GIST)TerminatedNCT00782834Phase 2Results posted
• Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade GliomasCompletedNCT00782626Phase 2Results posted
• Avastin and Temsirolimus Following Tyrosine Kinase Inhibitor Failure in Patients With Advanced Renal Cell CarcinomaCompletedNCT00782275Phase 2Results posted
• Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell LeukemiaCompletedNCT00782067Phase 2Results posted
• Personalized Treatment Selection for Metastatic Breast CancerTerminatedNCT00780676Phase 2Results posted
• A Dose-escalation Study of MK-8776 (SCH 900776) With and Without Gemcitabine in Participants With Solid Tumors or Lymphoma (MK-8776-002/P05248)CompletedNCT00779584Phase 1Results posted
• A Phase I Trial Evaluating mFOLFOX6 and Avastin With Nexavar as First-Line Treatment for Metastatic Colorectal CancerTerminatedNCT00779311Phase 1Results posted
• Prospective Study of Rapamycin for the Treatment of SLECompletedNCT00779194Phase 2Results posted
• A Dose Ranging Study of the Effect of Ruxolitinib Phosphate Cream When Applied to Participants With Plaque PsoriasisCompletedNCT00778700Phase 2Results posted
• Erlotinib Hydrochloride With or Without Cixutumumab in Treating Patients With Stage III or Stage IV Non-Small Cell Lung CancerCompletedNCT00778167Phase 1/2Results posted
• Phase II of Zactima Maintenance for Locally Advanced or Metastatic Non-small-cell Lung Carcinoma (NSCLC) Following Platinum-doublet ChemotherapyCompletedNCT00777179Phase 2Results posted
• Cediranib in Combination With Lomustine Chemotherapy in Recurrent GlioblastomaCompletedNCT00777153Phase 3Results posted
• Study Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast CancerCompletedNCT00777101Phase 2Results posted
• A Phase II Study of Dasatinib in Children and Adolescents With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML) or With Ph+ Leukemias Resistant or Intolerant to ImatinibCompletedNCT00777036Phase 2Results posted
• Clofarabine and Temsirolimus in Treating Older Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT00775593Phase 2Results posted
• R-(-)-Gossypol Acetic Acid in Treating Patients With Recurrent Extensive-Stage Small Cell Lung CancerCompletedNCT00773955Phase 2Results posted
• Double-blind Comparative Study of E3810 Tablets (10 or 20 mg b.i.d.) to Evaluate Efficacy and Safety in Patients With Refractory Reflux EsophagitisCompletedNCT00770913Phase 2/3Results posted
• Assess the Efficacy, Safety and Tolerability of Gefitinib (Iressa® 250mg) as Maintenance Therapy in Locally Advanced or Metastatic (Stage IIIB/IV) Non Small Cell Lung Cancer (NSCLC)CompletedNCT00770588Phase 4Results posted
• S0722: Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By SurgeryCompletedNCT00770120Phase 2Results posted
• MK-0646 and Gemcitabine +/- Erlotinib for Patients With Advanced Pancreatic CancerCompletedNCT00769483Phase 1/2Results posted
• A Randomized Trial Of PF-00299804 Taken Orally Versus Erlotinib Taken Orally For Treatment Of Advanced Non-Small Cell Lung Cancer That Has Progressed After One Or Two Prior Chemotherapy RegimenCompletedNCT00769067Phase 2Results posted
• Evaluation Of The Efficacy Of The Combination Of Axitinib With Pemetrexed And Cisplatin In The Treatment Of Non-Squamous Non-Small Cell Lung CancerCompletedNCT00768755Phase 1/2Results posted
• Open-Label Trial Of Oral PF-00299804 By Continuous Dosing In Patients With Recurrent Or Metastatic Head And Neck Squamous Cell CancerCompletedNCT00768664Phase 2Results posted
• Study Evaluating Safety And Tolerability, Solid TumorCompletedNCT00768469Phase 1Results posted
• Sunitinib in Recurrent and Refractory Ovarian, Fallopian Tube and Peritoneal CarcinomaCompletedNCT00768144Phase 2Results posted
• Treatment of Patients With RAD001 With Progressive SarcomaCompletedNCT00767819Phase 2Results posted
• Safety and Efficacy of Exemestane Plus Dasatinib Versus Placebo for Advanced ER+ Breast CancerCompletedNCT00767520Phase 2Results posted
• Pilot Study of the Evaluation of Subconjunctival Sirolimus in the Treatment of Bilateral GA Associated With AMDCompletedNCT00766649Phase 1/2Results posted
• Preoperative Chemotherapy (Gemcitabine and Erlotinib) With or Without Radiation TherapyTerminatedNCT00766636Phase 2Results posted
• Safety Evaluation of Dasatinib in Subjects With Scleroderma Pulmonary FibrosisCompletedNCT00764309Phase 1/2Results posted
• Study of Low-Dose Fractionated Radiotherapy in Patients With Locally Advanced Metastatic Pancreatic CancerCompletedNCT00761345Phase 1Results posted
• Nilotinib Versus Standard Imatinib (400/600 mg Every Day (QD)) Comparing the Kinetics of Complete Molecular Response for Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) Pts With Evidence of Persistent Leukemia by Real-time Quantitative Polymerase Chain Reaction (RQ-PCR)CompletedNCT00760877Phase 3Results posted
• Lapatinib in Women With Metastatic Breast Cancer Who Have Failed Prior Antihormone TherapyTerminatedNCT00759642Phase 2Results posted
• Treatment of Patients With Metastatic or Unresectable Gastrointestinal Stromal Tumors in First Line With NilotinibCompletedNCT00756509Phase 4Results posted
• Phase II Neoadjuvant in Inflammatory Breast CancerTerminatedNCT00756470Phase 2Results posted
• Sorafenib in Treating Non-Smokers or Former Light Smokers With Relapsed or Refractory Stage IIIB or Stage IV Non-Small Cell Lung CancerTerminatedNCT00754923Phase 2Results posted
• Erlotinib Hydrochloride in Treating Patients With Stage I-III Colorectal Cancer or AdenomaCompletedNCT00754494Phase 2Results posted
• Randomized Trial of Fulvestrant With or Without Dasatinib in Men and Postmenopausal Women Who Have Hormone Receptor-positive Advanced Breast Cancer Previously Treated With an Aromatase InhibitorCompletedNCT00754325Phase 2Results posted
• Zactima in Non Small Cell Lung Cancer (NSCLC) ELderly Patients In Combination With or Versus GemcitabineCompletedNCT00753714Phase 2Results posted
• Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior TherapyCompletedNCT00753688Phase 3Results posted
• Vandetanib Gemcitabine Or Placebo Plus Gemcitabine Or Vandetanib Monotherapy In Advanced Biliary Tract CancerCompletedNCT00753675Phase 2Results posted
• ZACtima FASlodex Trial in Postmenopausal Advance Breast Cancer Patients Instead of ZACtima FASlodex TrialTerminatedNCT00752986Phase 2Results posted
• A Placebo-Controlled Study of Saracatinib (AZD0530) in Patients With Recurrent Osteosarcoma Localized to the LungTerminatedNCT00752206Phase 2Results posted
• Nilotinib 800 Mg And Imatinib 800 Mg For The Treatment Of Patients With Gastrointestinal Stromal Tumors (Gist) Refractory To Imatinib 400 MgTerminatedNCT00751036Phase 3Results posted
• A Phase 2 Exploratory Study of Erlotinib and SNDX-275 in Participants With Non-small Cell Lung Carcinoma Who Are Progressing on ErlotinibTerminatedNCT00750698Phase 2Results posted
• Maintenance of Tarceva (Erlotinib) in Patients With Locally Advanced Head and Neck CancerTerminatedNCT00750555Phase 2Results posted
• Erlotinib Hydrochloride in Treating Participants With Muscle Invasive or Recurrent Urothelial CancerCompletedNCT00749892Phase 2Results posted
• Phase II Trial of BIBW 2992 (Afatinib) in Genetically Pre-screened Cancers With EGFR and/or HER2 Gene Amplification.TerminatedNCT00748709Phase 2Results posted
• A Study for Participants With Relapsed Cutaneous T-Cell LymphomaCompletedNCT00744991Phase 2Results posted
• Randomized Study Comparing Docetaxel Plus Dasatinib to Docetaxel Plus Placebo in Castration-resistant Prostate CancerCompletedNCT00744497Phase 3Results posted
• A Phase II Study of Oral Cyclophosphamide and Sirolimus (OCR) in Advanced SarcomaCompletedNCT00743509Phase 2Results posted
• Study Evaluating The Combination Of Neratinib And Capecitabine In Solid Tumors And Breast CancerCompletedNCT00741260Phase 1/2Results posted
• Phase II Study of Erlotinib, an EGFR Inhibitor in Metastatic EGFR-positive 'Triple Receptor-negative' Breast CancerTerminatedNCT00739063Phase 2Results posted
• Pemetrexed Disodium or Erlotinib Hydrochloride as Second-Line Therapy in Treating Patients With Advanced Non-small Cell Lung CancerTerminatedNCT00738881Phase 3Results posted
• Saracatinib in Treating Patients With Previously Treated Metastatic Pancreatic CancerCompletedNCT00735917Phase 2Results posted
• Trial Of AG-013736, Cisplatin, And Gemcitabine For Patients With Squamous Non-Small Cell Lung CancerCompletedNCT00735904Phase 2Results posted
• Phase I/II Trial of Radiation, Avastin and Tarceva for Pancreatic AdenocarcinomaCompletedNCT00735306Phase 1Results posted
• Multimodality Phase II Study in Prostate CancerTerminatedNCT00734851Phase 2Results posted
• Gemcitabine and Erlotinib Before and After Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by SurgeryCompletedNCT00733746Phase 2Results posted
• Nab-Paclitaxel and Bevacizumab Followed By Bevacizumab and Erlotinib in Metastatic Breast CancerCompletedNCT00733408Phase 2Results posted
• An Extension to Study MD7108240CompletedNCT00733304Phase 2Results posted
• A Safety Study Of Sunitinib In Combination With Pemetrexed In Patients With Advanced Solid MalignanciesCompletedNCT00732992Phase 1Results posted
• Pazopanib in Previously Treated Patients With Metastatic Renal Cell CarcinomaCompletedNCT00731211Phase 2Results posted
• Single-arm Trial of BIBW 2992 (Afatinib) in Demographically and Genotypically Selected NSCLC PatientsCompletedNCT00730925Phase 2Results posted
• Sutent + Taxol for Advanced Esophageal CancerCompletedNCT00730353Phase 2Results posted
• Study Of CP-751,871 In Combination With Sunitinib In Patients With Advanced Solid TumorsTerminatedNCT00729833Phase 1Results posted
• Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial CancerCompletedNCT00729586Phase 2Results posted
• RAD001 (Everolimus) Salvage Monotherapy in Advanced Gastric Cancer (AGC) Who Failed Standard First-line TreatmentCompletedNCT00729482Phase 2Results posted
• A Study To Test The Impact Of PF- 00299804 On How The Body Handles Dextromethorphan In Cancer PatientsCompletedNCT00728468Phase 1Results posted
• Sorafenib in Treating Patients With Locally Advanced or Metastatic Kidney CancerTerminatedNCT00727532Not applicableResults posted
• BIBW 2992 (Afatinib) With or Without Daily Temozolomide in the Treatment of Patients With Recurrent Malignant GliomaCompletedNCT00727506Phase 2Results posted
• Sorafenib, Cisplatin, and Etoposide in Treating Patients With Extensive-Stage Small Cell Lung CancerTerminatedNCT00726986Phase 2Results posted
• A Study In Patients With Advanced Solid TumorCompletedNCT00726752Phase 1Results posted
• A Phase II Study of GSK1363089 (Formerly XL880) for Papillary Renal-Cell Carcinoma (PRC)CompletedNCT00726323Phase 2Results posted
• Study to Determine the Safety and Efficacy of INCB018424 in Patients With Polycythemia Vera or Essential ThrombocythemiaTerminatedNCT00726232Phase 2Results posted
• Phase 2 Study of GSK1363089 (Formerly XL880) in Adults With Squamous Cell Cancer of the Head and NeckCompletedNCT00725764Phase 2Results posted
• Study of GSK1363089 in Metastatic Gastric CancerCompletedNCT00725712Phase 2Results posted
• A Long-Term Study of the Effects of Orally Administered SAR302503 in Patients With MyelofibrosisCompletedNCT00724334Phase 1/2Results posted
• Bevacizumab and Temsirolimus in Treating Patients With Recurrent or Persistent Endometrial CancerCompletedNCT00723255Phase 2Results posted
• Sorafenib and Fulvestrant in Treating Patients With Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Aromatase Inhibitor TherapyTerminatedNCT00722072Phase 2Results posted
• Novel Capecitabine Dosing Schedule in Combination With Lapatinib, Based on the Norton-Simon Mathematical Method in Patients With HER2 Overexpressed/Amplified, Trastuzumab (Herceptin) -Refractory, Metastatic Breast CancerCompletedNCT00721630Phase 2Results posted
• Study Of Letrozole With Or Without Palbociclib (PD-0332991) For The First-Line Treatment Of Hormone-Receptor Positive Advanced Breast CancerCompletedNCT00721409Phase 2Results posted
• Pazopanib Versus Sunitinib in the Treatment of Locally Advanced and/or Metastatic Renal Cell CarcinomaCompletedNCT00720941Phase 3Results posted
• Bevacizumab and Erlotinib After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or GliosarcomaCompletedNCT00720356Phase 2Results posted
• Erlotinib, Docetaxel, and Radiation Therapy in Stage III or Stage IV Squamous Cell Carcinoma of the Head and NeckCompletedNCT00720304Phase 2Results posted
• Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedNCT00720109Phase 2/3Results posted
• Chemotherapy and Radiation Therapy (RT) With or Without Vandetanib in Treating Patients With High-Risk Stage III or Stage IV Head and Neck CancerTerminatedNCT00720083Phase 2Results posted

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