Protein Kinase Inhibitors: all 15,278 studies that test it

Page 63 of 153. Open to participants first (2,556), then studies with results posted, then the rest; newest registration first within each.

• Safety and Efficacy of Bevacizumab Plus RAD001 Versus Interferon Alfa-2a and Bevacizumab for the First-line Treatment in Adult Patients With Kidney CancerCompletedNCT00719264Phase 2Results posted
• Saracatinib in Treating Patients With Relapsed or Refractory Thymoma or Thymic CancerTerminatedNCT00718809Phase 2Results posted
• A Study for Patients That Have Been Previously Been Treated in Waldenstrom's Macroglobulinemia or Multiple MyelomaCompletedNCT00718419Phase 2Results posted
• Cetuximab in Patients With Lung Adenocarcinoma Receiving Erlotinib That Have Developed "Acquired Resistance" to ErlotinibCompletedNCT00716456Phase 1/2Results posted
• Study to Determine the Maximum Tolerated Dose of BIBW 2992 (Afatinib) When Combined With Cisplatin/Paclitaxel or Cisplatin/5-FU in Patients With Advanced Solid TumoursCompletedNCT00716417Phase 1Results posted
• A Phase I/II Open Label Extension Study of BIBF 1120 Administered Orally Once or Twice Daily to Establish Safety, Pharmacokinetics and Efficacy in Patients With Advanced Solid Tumours and Clinical Benefit From Previous Therapy With BIBF 1120CompletedNCT00715403Phase 1Results posted
• Gemcitabine and Split-dose Cisplatin (GC) Plus Sorafenib in Chemotherapy-naïve Patients With Locally Advanced or Metastatic Urothelial CarcinomaTerminatedNCT00714948Phase 2Results posted
• Study Evaluating Conversion From Tacrolimus to Sirolimus in Stable Kidney Transplant Recipients Receiving MyforticCompletedNCT00713284Phase 4Results posted
• LUX-Lung 4: BIBW 2992 (Afatinib) Phase I Trial in Advanced Non Small Cell Lung Cancer Patients & Phase II Trial in Non Small Cell Lung Cancer Patients Failing Erlotinib or GefitinibCompletedNCT00711594Phase 2Results posted
• Sirolimus to Treat Diabetic Macular EdemaCompletedNCT00711490Phase 1/2Results posted
• A Randomised Placebo-Controlled Phase II Study of Continuous Maintenance Treatment With BIBF 1120 Following Chemotherapy in Patients With Relapsed Ovarian CancerCompletedNCT00710762Phase 2Results posted
• Open, Randomized Phase II Trial to Investigate the Efficacy and Safety of the PLK-1 Inhibitor BI 2536 in Patients With Advanced, Unresectable Pancreatic CancerCompletedNCT00710710Phase 2Results posted
• A Study for Participants With Metastatic Renal Cell CarcinomaCompletedNCT00709995Phase 2Results posted
• Phase II Lapatinib Plus Nab-Paclitaxel As First And Second Line Therapy In her2+ MBCCompletedNCT00709761Phase 2Results posted
• Lapatinib + Vinorelbine in ErbB2 Overexpressing, First or Second Line Metastatic Breast Cancer SubjectsTerminatedNCT00709618Phase 2Results posted
• BIBW 2992 and Letrozole in Hormonoresistant Metastatic Breast CancerCompletedNCT00708214Phase 2Results posted
• Safety And Efficacy Study Of Sunitinib Malate As First-Line Systemic Therapy In Chinese Patients With Metastatic Renal Cell CarcinomaCompletedNCT00706706Phase 4Results posted
• Neoadjuvant Dasatinib and Radical Cystectomy for Transitional Cell Carcinoma of the BladderCompletedNCT00706641Not applicableResults posted
• A Multi-centre 3-arm Randomised Phase II Trial of BIBF 1120 Versus BIBW 2992 Versus Sequential Administration of BIBF 1120 and BIBW 2992 in Patients With Hormone-resistant Prostate CancerCompletedNCT00706628Phase 2Results posted
• Thyroid Hormones Homeostasis and Energy Metabolism Changes During Stimulation of Endogenously Secreted Bile Acids (BAs)CompletedNCT00706381Phase 3Results posted
• A Study of PF-04217903 in Patients With Advanced CancerTerminatedNCT00706355Phase 1Results posted
• Pilot Study of Fostamatinib Disodium/R935788 for the Treatment of Adult Refractory Immune Thrombocytopenic Purpura (ITP)CompletedNCT00706342Phase 2Results posted
• Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast CancerCompletedNCT00706030Phase 1/2Results posted
• Study of CGC-11047 When Used in Individual Combinations With 1) Gemcitabine or 2) Docetaxel or 3) Bevacizumab or 4) Erlotinib or 5) Cisplatin or 6) 5-Flurouracil or 7) Sunitinib in Patients With Advanced Solid Tumors or LymphomaCompletedNCT00705874Phase 1Results posted
• Efficacy of XL184 (Cabozantinib) in Advanced Medullary Thyroid CancerCompletedNCT00704730Phase 3Results posted
• Study of XL184 (Cabozantinib) in Adults With Glioblastoma MultiformeCompletedNCT00704288Phase 2Results posted
• Sunitinib in Treating Patients With Relapsed or Refractory Esophageal or Gastroesophageal Junction CancerCompletedNCT00702884Phase 2Results posted
• Imatinib Mesylate to Treat Skin Changes in Patients With Chronic Graft-Versus-Host DiseaseCompletedNCT00702689Phase 2Results posted
• Nilotinib and Imatinib Mesylate After Donor Stem Cell Transplant in Treating Patients With ALL or CMLCompletedNCT00702403Phase 1/2Results posted
• Safety and Efficacy of RAD001 in Participants With Mantle Cell Lymphoma Who Are Refractory or Intolerant to Velcade® TherapyCompletedNCT00702052Phase 2Results posted
• A Study of First Line Treatment With Tarceva (Erlotinib) in Combination With Gemcitabine in Patients With Unresectable Advanced and/or Metastatic Non-Small Cell Lung CancerCompletedNCT00701558Phase 2Results posted
• Dasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By SurgeryCompletedNCT00700882Phase 2Results posted
• Study of CBP501 + Pemetrexed + Cisplatin on MPM (Phase I/II)CompletedNCT00700336Phase 1/2Results posted
• Cixutumumab and Temsirolimus in Treating Patients With Locally Recurrent or Metastatic Breast CancerCompletedNCT00699491Phase 1/2Results posted
• Study Of Sunitinib Malate Versus Sorafenib In Patients With Inoperable Liver CancerTerminatedNCT00699374Phase 3Results posted
• Pemetrexed and/or Sunitinib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung CancerCompletedNCT00698815Phase 2Results posted
• Study of MLN8237 in Participants With Advanced Hematological MalignanciesCompletedNCT00697346Phase 1Results posted
• Study of Gemcitabine and Erlotinib Plus Sorafenib (GES) in Metastatic Pancreatic CancerCompletedNCT00696696Phase 2Results posted
• Randomized Phase II Trial of Letrozole With or Without Dasatinib as First and Second-line Treatment for Hormone Receptor-positive, HER2-negative Post-menopausal Breast Cancer That is Unresectable, Locally Recurrent or MetastaticCompletedNCT00696072Phase 2Results posted
• Irinotecan, Carboplatin, and Sunitinib in First Line Extensive-Stage Small Cell Lung CancerCompletedNCT00695292Phase 2Results posted
• Sunitinib for Metastatic Renal Cell Cancer With Imaging Biomarker Assessments for the Early Prediction of Tumor ResponseCompletedNCT00694096Phase 1Results posted
• Sunitinib Malate as Maintenance Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Previously Treated With Combination ChemotherapyCompletedNCT00693992Phase 3Results posted
• Sorafenib as Adjuvant Treatment in the Prevention Of Recurrence of Hepatocellular Carcinoma (STORM)CompletedNCT00692770Phase 3Results posted
• Evaluation Of Hepatic Impairment On AG-013736 PharmacokineticsCompletedNCT00692341Phase 1Results posted
• RAPTOR: RAD001 as Monotherapy in the Treatment of Advanced Papillary Renal Cell Tumors Program in EuropeCompletedNCT00688753Phase 2Results posted
• RAMSETE: RAD001 in Advanced and Metastatic Silent Neuro-endocrine Tumors in EuropeCompletedNCT00688623Phase 2Results posted
• Sorafenib, Lenalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple MyelomaTerminatedNCT00687674Phase 1Results posted
• Study of Vandetanib Combined With Chemotherapy to Treat Advanced Non-small Cell Lung CancerCompletedNCT00687297Phase 2Results posted
• Comparison Of 5 CP-690,550 Doses Vs. Placebo, For The Treatment Of Rheumatoid Arthritis In JapanCompletedNCT00687193Phase 2Results posted
• Trial Assessing Zactima Against Placebo in Prostate Cancer Subjects Undergoing Intermittent Androgen Deprivation Hormonal TherapyTerminatedNCT00686036Phase 2Results posted
• Gleevec in Relapsed/Refractory T Cell Non-Hodgkin's LymphomaCompletedNCT00684411Phase 2Results posted
• Docetaxel With or Without Vandetanib in Treating Patients With Metastatic Stomach Cancer or Gastroesophageal Junction CancerTerminatedNCT00683787Phase 2Results posted
• LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus LapatinibCompletedNCT00680901Phase 3Results posted
• Topical CP-690,550 For Chronic Plaque PsoriasisCompletedNCT00678561Phase 2Results posted
• Axitinib (AG 013736) As Second Line Therapy For Metastatic Renal Cell CancerCompletedNCT00678392Phase 3Results posted
• A Study to Assess Sorafenib Alone and in Combination With Low-Dose Interferon Following Unsuccessful Treatment With Sunitinib in Patients With Advanced Renal Cell Cancer.TerminatedNCT00678288Phase 2Results posted
• Effectiveness and Safety of 3 Dosing Regimens of CP-690,550 to Placebo in Subjects With Moderate to Severe Chronic Plaque PsoriasisCompletedNCT00678210Phase 2Results posted
• Pilot Study of Imatinib Mesylate to Treat Nephrogenic Systemic FibrosisCompletedNCT00677092Phase 2Results posted
• Sunitinib Plus Prednisone In Patients With Metastatic Castration-Resistant Prostate Cancer After Failure Of Docetaxel ChemotherapyTerminatedNCT00676650Phase 3Results posted
• A Biomarker Identification Trial of Tarceva (Erlotinib) in Patients With Advanced Pancreatic CancerCompletedNCT00674973Phase 2Results posted
• INCB018424 in Patients With Advanced Hematologic MalignanciesCompletedNCT00674479Phase 2Results posted
• Sunitinib Malate to Treat Advanced Eye Disease in Patients With Von Hippel-Lindau SyndromeTerminatedNCT00673816Phase 1/2Results posted
• Pilot Trial of "Chemo-Switch" Regimen to Treat Advanced MelanomaTerminatedNCT00673361Phase 2Results posted
• Study of Sunitinib Malate in Patients With Newly Diagnosed Prostate Cancer Prior to ProstatectomyCompletedNCT00672594Phase 2Results posted
• Ph II Erlotinib + Sirolimus for Pts w Recurrent Malignant Glioma MultiformeCompletedNCT00672243Phase 2Results posted
• Raptiva and Sirolimus in Islet Transplantation for Type 1 DiabetesTerminatedNCT00672204Phase 1/2Results posted
• Phase (Ph) II Bevacizumab + Erlotinib for Patients (Pts) With Recurrent Malignant Glioma (MG)CompletedNCT00671970Phase 2Results posted
• A Phase II Evaluation of Dasatinib (Sprycel®, NSC #732517) in the Treatment of Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal CarcinomaCompletedNCT00671788Phase 2Results posted
• Dose Escalation Study With MK-2206 in Patients With Locally Advanced or Metastatic Solid Tumors (MK-2206-002)CompletedNCT00670488Phase 1Results posted
• Rho Kinase (ROCK) Inhibition in Carotid AtherosclerosisTerminatedNCT00670202Phase 2Results posted
• Saracatinib in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By SurgeryCompletedNCT00669019Phase 2Results posted
• Study Of Sunitinib With FOLFIRI In Colorectal CancerCompletedNCT00668863Phase 2Results posted
• Sutent Adjunctive Treatment of Differentiated Thyroid CancerCompletedNCT00668811Phase 2Results posted
• Study of Temzolomide and Gleevec in Advanced MelanomaTerminatedNCT00667953Phase 1/2Results posted
• Tandutinib Plus Bevacizumab to Treat Recurrent Brain TumorsCompletedNCT00667394Phase 2Results posted
• Chemotherapy and Lapatinib or Trastuzumab in Treating Women With HER2/Neu-Positive Metastatic Breast CancerCompletedNCT00667251Phase 3Results posted
• Study Of PF-00562271, Including Patients With Pancreatic, Head And Neck, Prostatic NeoplasmsCompletedNCT00666926Phase 1Results posted
• R-(-)-Gossypol and Androgen Ablation Therapy in Treating Patients With Newly Diagnosed Metastatic Prostate CancerCompletedNCT00666666Phase 2Results posted
• Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid ArthritisCompletedNCT00665925Phase 2Results posted
• Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis (Taski-3)CompletedNCT00665626Phase 2Results posted
• A Phase II Uncontrolled Study of BAY73-4506 in Previously Untreated Patients With Metastatic or Unresectable RCCCompletedNCT00664326Phase 2Results posted
• Study Of Sunitinib With Capecitabine In Breast CancerCompletedNCT00662025Phase 2Results posted
• Gemcitabine and Sorafenib in Advanced Biliary Tract Cancer (GEMSO)CompletedNCT00661830Phase 2Results posted
• Long-Term, Open-Label Study Of CP-690,550 For Treatment Of Rheumatoid Arthritis In JapanCompletedNCT00661661Phase 3Results posted
• Pemetrexed or Docetaxel With or Without Erlotinib in Stage IIIB or Stage IV Non-Small Cell Lung CancerCompletedNCT00660816Phase 2Results posted
• Efficacy and Safety of Zactima™ in Patients With Castration-refractory Metastatic Prostate CancerCompletedNCT00659438Phase 2Results posted
• AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue SarcomaCompletedNCT00659360Phase 2Results posted
• Extension Study Of Subjects From Study A3921030 For The Prevention Of Acute Rejection In Kidney Transplant PatientsCompletedNCT00658359Phase 2Results posted
• Concentration Controlled Everolimus With Reduced Dose Cyclosporine Versus Mycophenolate Mofetil With Standard Dose Cyclosporine in de Novo Renal Transplant Adult Recipients Treated With Basiliximab and CorticosteroidsCompletedNCT00658320Phase 3Results posted
• Exploratory Study of Sunitinib Malate as a Component of Neoadjuvant Therapy for Breast CancerCompletedNCT00656669Not applicableResults posted
• BIBW 2992 and BSC Versus Placebo and BSC in Non-small Cell Lung Cancer Patients Failing Erlotinib or Gefitinib (LUX-LUNG 1)CompletedNCT00656136Phase 3Results posted
• The Effect of Omeprazole on the Pharmacokinetics of Dasatinib in Healthy SubjectsCompletedNCT00655746Phase 1Results posted
• Phase II Trial of Sorafenib (Nexavar) in Patients With Advanced Thyroid CancerCompletedNCT00654238Phase 2Results posted
• A Dose-Escalation to Rash Study of Tarceva (Erlotinib) Plus Gemcitabine in Patients With Metastatic Pancreatic CancerCompletedNCT00652366Phase 2Results posted
• APRiCOT-L: Study to Evaluate Efficacy and Safety of Apricoxib With Erlotinib in Patients With Non-small Cell Lung CancerCompletedNCT00652340Phase 2Results posted
• A Phase I Clinical and Pharmacodynamic Study of MLN8237, A Novel Aurora A Kinase Inhibitor, in Participants With Advanced MalignanciesCompletedNCT00651664Phase 1Results posted
• Treatment of Refractory Metastatic Renal Cell Carcinoma With Bevacizumab and RAD001 (Everolimus)TerminatedNCT00651482Phase 2Results posted
• Daunorubicin, Cytarabine, and Midostaurin in Treating Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT00651261Phase 3Results posted
• A Study of ARRY-438162 in Patients With Rheumatoid ArthritisCompletedNCT00650767Phase 2Results posted
• A Dose Escalation Study of Adavosertib (MK-1775) in Combination With Either Gemcitabine, Cisplatin, or Carboplatin in Adults With Advanced Solid Tumors (MK-1775-001)CompletedNCT00648648Phase 1Results posted

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