Protein Kinase Inhibitors: all 15,147 studies that test it

Page 128 of 152. Open to participants first (2,533), then studies with results posted, then the rest; newest registration first within each.

• A Dose-finding Study of a Combination of Imatinib and BKM120 in the Treatment of 3rd Line GIST PatientsCompletedNCT01468688Phase 1
• A Study of AC220 Given After Transplant in Subjects With Acute Myeloid Leukemia (AML)CompletedNCT01468467Phase 1
• AZD7451 for Recurrent GliomasCompletedNCT01468324Phase 1
• Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk NeuroblastomaCompletedNCT01467986Phase 2
• Defining the Triple Negative Breast Cancer Kinome Response to GSK1120212CompletedNCT01467310Early Phase 1
• Study of MK 2206 in Patients With Relapsed or Refractory Diffuse Large B Cell LymphomaTerminatedNCT01466868Phase 2
• A Research Study to Assess if CC-930 is Safe in Treating Subjects With Discoid Lupus ErythematosusTerminatedNCT01466725Phase 2
• A Study of the IGF-1R Inhibitor AXL1717 in Combination With Gemcitabine HCL and Carboplatin to Treat Non-small-cell Lung Cancer (NSCLC)CompletedNCT01466647Phase 1
• Everolimus in Refractory Testicular Germ Cell CancerCompletedNCT01466231Phase 2
• Phase I/II Study of Postoperative Adjuvant Chemoradiation for Advanced-Stage Cutaneous Squamous Cell Carcinoma of the Head and Neck (cSCCHN)WithdrawnNCT01465815Phase 1/2
• Dose Escalation Of Icotinib In Previously Treated Patients With Routine DoseCompletedNCT01465243Phase 4
• Study to Investigate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of Single & Repeat Doses of GSK2269557CompletedNCT01462617Phase 1
• Concurrent Chemoradiotherapy With Famitinib for Patients With Locally Advanced Nasopharyngeal CarcinomaCompletedNCT01462474Phase 1
• Study of Everolimus and Low-dose Cyclophosphamide in Patients With Metastatic Renal Cell CancerCompletedNCT01462214Phase 1/2
• Double-blind Placebo-controlled Pilot Study of Sirolimus in Idiopathic Pulmonary Fibrosis (IPF)CompletedNCT01462006Not applicable
• Efficacy,Tolerability,Safety of Temsirolimus in Women With Platinum-refractory Ovarian Carcinoma or Advanced Endometrial CarcinomaCompletedNCT01460979Phase 2
• Comparison of Imatinib Versus Dasatinib in Patients With Newly-diagnosed Chronic Phase Chronic Myeloid LeukaemiaCompletedNCT01460693Phase 3
• A Phase I/IIa, First Time in Human, Study of GSK2636771 in Subjects With Advanced Solid Tumors With Phosphatase and Tensin Homolog (PTEN) DeficiencyCompletedNCT01458067Phase 1
• Nilotinib and LDE225 in the Treatment of Chronic or Accelerated Phase Myeloid Leukemia in Patients Who Developed Resistance to Prior TherapyCompletedNCT01456676Phase 1
• Study to Evaluate the Safety and Efficacy of Switching Calcineurin Inhibitor to Everolimus After Kidney Transplantation in AdultsStatus unknownNCT01455649Phase 4
• Clinical Trial to Determine the MTD of HM781-36B in Patients With Advanced Solid TumorsCompletedNCT01455584Phase 1
• Phase I Study to Determine the Maximum Tolerated Dose and to Assess the Safety and Pharmacokinetic Profile of HM781-36B in Patients With Advanced Solid TumorsCompletedNCT01455571Phase 1
• A Study of GDC-0980 in the Treatment of Recurrent or Persistent Endometrial CarcinomaCompletedNCT01455493Phase 2
• TUSC2-nanoparticles and Erlotinib in Stage IV Lung CancerTerminatedNCT01455389Phase 1/2
• Pazopanib, Lapatinib or Trastuzumab in Subjects With Solid TumorsCompletedNCT01454804Phase 1
• A Phase I Study of Lapatinib (Tykerb) Plus Ixabepilone (Ixempra) as 2nd-line Treatment for Patients With HER-2 Overexpressed Recurrent or Persistent Endometrial Carcinoma or CarcinosarcomaStatus unknownNCT01454479Phase 1
• Everolimus in Combination With DHAP in Patients With Relapsed or Refractory Hodgkin LymphomaCompletedNCT01453504Phase 1/2
• Masitinib in Primary Progressive Multiple Sclerosis or Relapse-free Secondary Progressive Multiple SclerosisCompletedNCT01450488Phase 2
• Pemetrexed Disodium and Sorafenib Tosylate in Treating Patients With Advanced Solid TumorsCompletedNCT01450384Phase 1
• PF-00299804 in Patients With Head and Neck Squamous Cell CarcinomaCompletedNCT01449201Phase 2
• Masitinib in Treatment of Patients With Severe Persistent Asthma Treated With Oral CorticosteroidsCompletedNCT01449162Phase 3
• A Phase Ib Study of MEK162 Plus BYL719 in Adult Patients With Selected Advanced Solid TumorsCompletedNCT01449058Phase 1
• A Study of GSK2110183 in Subjects With Proteasome Inhibitor Refractory Multiple MyelomaWithdrawnNCT01445587Phase 2
• Dasatinib in Combination With Bevacizumab to Treat Advanced Solid TumorsCompletedNCT01445509Phase 1
• A Phase I Trial of Enzastaurin (LY317615) in Combination With Carboplatin in Adults With Recurrent GliomasCompletedNCT01445119Phase 1
• Evaluate the Efficacy of Sorafenib in Renal Cell Carcinoma Patients After a Radical Resection of the MetastasesStatus unknownNCT01444807Phase 2
• Pharmacokinetics (PK) of TKI258 in Cancer Patients With Normal and Impaired Hepatic FunctionCompletedNCT01443481Phase 1
• Efficacy of Gemcitabine With Pazopanib as Second Line Treatment in Patient With Metastatic or Relapsed UterineCompletedNCT01442662Phase 2
• Study of GDC-0980 Versus Everolimus in Participants With Metastatic Renal Cell Carcinoma Who Have Progressed on or Following Vascular Endothelial Growth Factor- (VEGF) Targeted TherapyCompletedNCT01442090Phase 2
• A Study Of Crizotinib Plus VEGF Inhibitor Combinations In Patients With Advanced Solid Tumors.WithdrawnNCT01441388Phase 1
• BIBF 1120 as Second Line Treatment for Small Cell Lung CancerCompletedNCT01441297Phase 2
• -02341066 and PF-00299804 for Advanced Non-Small Cell Lung CancerTerminatedNCT01441128Phase 1
• Dasatinib, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV or Recurrent Endometrial CancerCompletedNCT01440998Phase 1
• Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and CholangiocarcinomaCompletedNCT01438554Phase 1
• Study of GDC-0941 or GDC-0980 With Fulvestrant Versus Fulvestrant in Advanced or Metastatic Breast Cancer in Participants Resistant to Aromatase Inhibitor TherapyCompletedNCT01437566Phase 2
• TKM 080301 for Primary or Secondary Liver CancerCompletedNCT01437007Phase 1
• A Study of Investigational SAR256212 in Combination With SAR245408 in Patients With Solid Tumor CancersCompletedNCT01436565Phase 1
• Veliparib and Dinaciclib in Treating Patients With Advanced Solid TumorsActive, not recruitingNCT01434316Phase 1
• Entinostat, Lapatinib Ditosylate and Trastuzumab in Treating Patients With Locally Recurrent or Distant Relapsed Metastatic Breast Cancer Previously Treated With Trastuzumab OnlyCompletedNCT01434303Phase 1
• Efficacy and Safety of Masitinib in the Treatment of Progressive Multiple SclerosisCompletedNCT01433497Phase 3
• Panobinostat and Ruxolitinib in Primary Myelofibrosis, Post-polycythemia Vera-myelofibrosis or Post-essential Thrombocythemia-myelofibrosisCompletedNCT01433445Phase 1
• Phase 1 Trial With SIR-Spheres and Cetuximab +/- ErlotinibWithdrawnNCT01432119Phase 1
• AT9283 in Treating Young Patients With Relapsed or Refractory Acute LeukemiaCompletedNCT01431664Phase 1
• Study of Dalotuzumab Alone and With Ridaforolimus in Pediatric Participants With Advanced Solid Tumors (MK-8669-062 AM1)CompletedNCT01431547Phase 1
• Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss PatientsCompletedNCT01430572Phase 1
• Safety and Efficacy of AEB071 in Metastatic Uveal Melanoma PatientsCompletedNCT01430416Phase 1
• A Study to Assess the Bioavailability of ASP015KCompletedNCT01430078Phase 1
• Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Tacrolimus in Healthy VolunteersCompletedNCT01430065Phase 1
• PK and Safety of Midostaurin in Subjects With Impaired Hepatic Function and Subjects With Normal Hepatic FunctionCompletedNCT01429337Phase 1
• Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis RegimensActive, not recruitingNCT01428973Phase 2
• Ph 1b Study to Evaluate GSK2110183 in Combination With Bortezomib and Dexamethasone in Subjects With Multiple MyelomaCompletedNCT01428492Phase 1
• Combination Study of GSK1120212 With Gemcitabine in Subjects With Solid TumorsCompletedNCT01428427Phase 1
• A Phase I Study of E7050 in Subjects With Solid TumorsCompletedNCT01428141Phase 1
• Phase 1b/2 Study of Retaspimycin HCl (IPI-504) in Combination With Everolimus in KRAS Mutant Non-small Cell Lung CancerCompletedNCT01427946Phase 1/2
• Evaluation of Afatinib in Maintenance Therapy in Squamous Cell Carcinoma of the Head and NeckCompletedNCT01427478Phase 3
• Randomized RT +/- Lapatinib for Advanced Solid Tumor Cancer Patients Receiving Radiation Therapy for Metastatic DiseaseTerminatedNCT01427322Early Phase 1
• Phase II Study of Cetuximab With or Without OSI-906 in Head and Neck Squamous Cell Carcinoma (HNSCC)WithdrawnNCT01427205Phase 2
• Dasatinib and Cyclosporine in Treating Patients With Chronic Myelogenous Leukemia Refractory or Intolerant to Imatinib MesylateTerminatedNCT01426334Phase 1
• Sorafenib for Patients With Extensive KeloidsTerminatedNCT01425216Phase 2
• Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic LeukemiaActive, not recruitingNCT01424982Phase 2
• Everolimus in de Novo Liver Transplantation: a Multicentre Randomized StudyStatus unknownNCT01423708Phase 2
• Combination of Weekly Paclitaxel With Neratinib and Trastuzumab in Women With Metastatic HER2-positive Breast CancerCompletedNCT01423123Phase 1
• Safety Study Evaluating Twice-Daily Administration of Momelotinib in Primary Myelofibrosis or Post-Polycythemia Vera or Post-Essential Thrombocythemia MyelofibrosisCompletedNCT01423058Phase 1/2
• Bioequivalence of 2 Formulations of TKI258 in Patients With Advanced Solid TumorsCompletedNCT01421004Phase 1
• Study With SAR302503 in Patients With Polycythemia Vera or Essential ThrombocythemiaCompletedNCT01420783Phase 2
• Phase 2 Study of SAR302503 in Patients With MyelofibrosisCompletedNCT01420770Phase 2
• Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Oral Doses of GLPG0634 in Healthy SubjectsCompletedNCT01419990Phase 1
• A Study to Evaluate The Pharmacokinetics Of Crizotinib (PF-02341066) In Subjects With Impaired Renal FunctionCompletedNCT01419041Phase 1
• Dovitinib in Adenoid Cystic CarcinomaCompletedNCT01417143Phase 2
• Temsirolimus In Phase 0CompletedNCT01417065Early Phase 1
• A Phase I Study of Henatinib in Patients With Advanced Solid MalignanciesTerminatedNCT01416623Phase 1
• Absolute Bioavialability of GSK1120212CompletedNCT01416337Phase 1
• Research of Biomarkers of Activity and Efficacy of BIBW2992 in Untreated Non-metastatic HNSCC PatientsCompletedNCT01415674Phase 2
• Efficacy and Safety Study of Afatinib to Treat Lung Cancer PatientsCompletedNCT01415011Phase 2
• An Extension Study of Linifanib (ABT-869) in Subjects With Advanced or Metastatic Solid TumorsCompletedNCT01413893Phase 1
• Iodine I 131 and Pazopanib Hydrochloride in Treating Patients With Recurrent and/or Metastatic Thyroid Cancer Previously Treated With Iodine I 131 That Cannot Be Removed By SurgeryCompletedNCT01413113Phase 1
• Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform NeurofibromasCompletedNCT01412892Phase 2
• A Phase II Study With Tumor Molecular Pharmacodynamic (MPD) Evaluation of Oral mTOR-inhibitor Everolimus (RAD001) 10 mg Daily in Patients Suffering From Classic or Endemic Kaposi's SarcomaTerminatedNCT01412515Phase 2
• Phase I Study of PI3(Phosphoinositol 3)-Kinase Inhibitor BAY80-6946 With Paclitaxel in Patients With Advanced CancerCompletedNCT01411410Phase 1
• TORI 104 Pre-Surgical DasatinibWithdrawnNCT01410708Phase 2
• Masitinib in Refractory Active Rheumatoid ArthritisTerminatedNCT01410695Phase 2/3
• Study Combining SAR245409 With Rituximab or Bendamustine Plus Rituximab in Patients With Indolent Lymphoma, Mantle Cell Lymphoma and Chronic Lymphocytic LeukemiaCompletedNCT01410513Phase 1
• Erlotinib Versus Vinorelbine/Cisplatin as Adjuvant Treatment in Stage IIIA NSCLC Patients With EGFR MutationsStatus unknownNCT01410214Phase 2
• Palliative Treatments for Patients With Advanced Hepatocellular Carcinoma (HCC)CompletedNCT01409499Phase 4
• Antiandrogen Therapy With or Without Axitinib Before Surgery in Treating Patients With Previously Untreated Prostate Cancer With Known or Suspected Lymph Node MetastasisCompletedNCT01409200Phase 2
• Study of the Pharmacokinetics and Pharmacodynamics of Crystalline PX-866 Tablets and Amorphous PX-866 Capsules in Healthy VolunteersCompletedNCT01408316Phase 1
• Rotating Pazopanib and Everolimus to Avoid ResistanceCompletedNCT01408004Phase 2
• Erlotinib Versus Gemcitabine/Cisplatin as (Neo)Adjuvant Treatment in Non-small Cell Lung CancerStatus unknownNCT01407822Phase 2/3
• Study of Pazopanib, Paclitaxel, and Carboplatin in Patients With Advanced Solid TumorsTerminatedNCT01407562Phase 1
• Study of PWT33597 Mesylate in Subjects With Advanced MalignanciesCompletedNCT01407380Phase 1

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