Protein Kinase Inhibitors: all 15,147 studies that test it
Page 129 of 152. Open to participants first (2,533), then studies with results posted, then the rest; newest registration first within each.
- Nilotinib With Radiation for High Risk ChordomaCompletedNCT01407198Phase 1
- A Study to Assess the Pharmacokinetics of ASP015K in Healthy Male SubjectsCompletedNCT01406132Phase 1
- Feasibility Study to Estimate Number of Patients With Precancerous Areas in Their Airways and the Response to GefitinibTerminatedNCT01405846Phase 2
- Sorafenib in First-line Treatment of Advanced B Child Hepatocellular CarcinomaTerminatedNCT01405573Phase 3
- Gefitinib Versus Vinorelbine/Platinum as Adjuvant Treatment in Stage II-IIIA(N1-N2) NSCLC With EGFR MutationStatus unknownNCT01405079Phase 3
- Drug-drug Interaction Study With Metformin and ImatinibCompletedNCT01404715Phase 1
- Japanese BAY80-6946 Monotherapy Phase I StudyCompletedNCT01404390Phase 1
- Neo-adjuvant Temsirolimus in Patients With Advanced Renal Cell CarcinomaCompletedNCT01404104Not applicable
- A Study of Investigational SAR245409 in Patients With Certain Lymphoma or LeukemiaCompletedNCT01403636Phase 2
- Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin LymphomaCompletedNCT01403415Phase 1
- Study of AEB071 (a Protein Kinase C Inhibitor) in Patients With CD79-mutant Diffuse Large B-Cell LymphomaTerminatedNCT01402440Phase 1
- Cytochrom p450 3A4 and 1A2 Phenotyping for the Individualization of Treatment With Sunitinib or Erlotinib in Cancer PatientsCompletedNCT01402089Phase 4
- Effect of Rifampin on the Pharmacokinetics of Linifanib in Subjects With Advanced or Metastatic Solid TumorsCompletedNCT01401933Phase 1
- Study of an Investigational Drug, ASP3026, in Patients With Solid TumorsCompletedNCT01401504Phase 1
- Efficacy of Nilotinib Versus Imatinib in Ph+ CML in Early CP Who Have a Suboptimal Molecular Response to ImatinibStatus unknownNCT01400074Phase 3
- Efficacy of Certican® in Combination With Myfortic® in RenalStatus unknownNCT01399242Phase 4
- Sorafenib Maintenance Therapy for Patients With AML After Allogeneic Stem Cell TransplantCompletedNCT01398501Phase 1
- Effects of Gastric pH on the Pharmacokinetics of DasatinibCompletedNCT01398046Phase 1
- GINECO-EN102b - BKM120 as Monotherapy in the Treatment of Initial or Recurrent Metastatic Endometrial CancerCompletedNCT01397877Phase 2
- Study to Assess Safety, Tolerability and Preliminary Efficacy of BKM120, PI3K Kinase Inhibitor, With Advanced LeukemiasCompletedNCT01396499Phase 1
- A Phase II Study of Sunitinib or Temsirolimus in Patients With Advanced Rare TumoursActive, not recruitingNCT01396408Phase 2
- Cyclophosphamide and Pulse Dexamethasone With Rapamycin or HydroxychloroquineCompletedNCT01396200Early Phase 1
- A Trial Looking at Nilotinib to Treat Acral and Mucosal Melanoma Skin Cancer That Has SpreadCompletedNCT01395121Phase 2
- A Study to Test the Ability of and Safety of GSK2110183 in Treating Langerhans Cell HistiocytosisCompletedNCT01395004Phase 2
- PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade GliomaCompletedNCT01393912Phase 1
- Safety and Pharmacokinetics of SAR245408 Daily Oral in Patients With Solid TumorsCompletedNCT01392924Phase 1
- Phase Ib Study of PI3(Phosphoinositol 3)-Kinase Inhibitor Copanlisib With MEK (Mitogen-activated Protein Kinase) Inhibitor Refametinib (BAY86-9766) in Patients With Advanced CancerCompletedNCT01392521Phase 1
- HYPAZ: Hypertension Induced by PazopanibTerminatedNCT01392352Phase 2
- Famitinib in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal Carcinoma (NPC)CompletedNCT01392235Phase 2
- Study of SAR125844 Single Agent Administered as Slow Intravenous Infusion in Adult Patients With Advanced Malignant Solid TumorsCompletedNCT01391533Phase 1
- A Study to Assess AC220 Given in Combination With Induction and Consolidation Therapy in Newly Diagnosed Acute Myeloid Leukemia (AML)CompletedNCT01390337Phase 1
- Efficacy and Safety of a Neoadjuvant Treatment in Pancreatic CancerCompletedNCT01389440Phase 2
- Escalating Doses of Torisel in Combination With Three Chemotherapies Regimens: R-CHOP, R-FC or R-DHA for Patients With Relapsed/Refractory Mantle Cell Lymphoma (MCL).CompletedNCT01389427Phase 1/2
- Irinotecan, Cetuximab and Everolimus to Patients With Metastatic Colorectal CancerCompletedNCT01387880Phase 2
- A Study of BYL719 in Adult Patients With Advanced Solid MalignanciesCompletedNCT01387321Phase 1
- Study in Healthy Males to Assess the Bioavailability of 4 Different Fostamatinib TabletsCompletedNCT01387308Phase 1
- Study to Investigate the Absorption, Distribution, Metabolism and Elimination of [14C]GSK1120212CompletedNCT01387204Phase 1
- A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015KCompletedNCT01387087Phase 1
- Single Dose Study of [14C]-Labelled AMG 706 in Patients With Advanced Solid TumorsCompletedNCT01386866Phase 1
- Pazopanib, Docetaxel, Prednisone ProstateCompletedNCT01385228Phase 1
- Phase I Study of CUDC-101 With Cisplatin and Radiation in Subjects With Head & Neck CancerCompletedNCT01384799Phase 1
- Safety and Preliminary Efficacy of GLPG0634 in Methotrexate-refractory Active Rheumatoid Arthritis PatientsCompletedNCT01384422Phase 2
- Sirolimus and Gold Sodium Thiomalate in Treating Patients With Advanced Squamous Non-Small Cell Lung CancerWithdrawnNCT01383668Phase 1
- Sorafenib Tosylate, Bevacizumab, Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil in Treating Patients With Metastatic Colorectal CancerCompletedNCT01383343Phase 1
- To Compare Relative Bioavailability of Two Clinical Formulations of Linifanib.CompletedNCT01381341Phase 1
- A Phase 3, Randomized, Double-Blinded, Placebo-Controlled Study of ARQ 197 Plus Erlotinib Versus Placebo Plus ErlotinibTerminatedNCT01377376Phase 3
- Pazopanib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaStatus unknownNCT01377298Phase 2
- A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal MelanomaStatus unknownNCT01377025Phase 2
- Pre-operative 5-Fluorouracil (5-FU) and Sorafenib With External Radiation in Locally Advanced Rectal CancerCompletedNCT01376453Phase 1
- Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryActive, not recruitingNCT01375829Phase 1
- Efficacy of Sirolimus In Liver Transplantation for Hepatocellular Carcinoma (HCC)CompletedNCT01374750Phase 2
- Bioequivalence And Food Effect Study Of Bosutinib In Healthy SubjectsCompletedNCT01374139Phase 1
- GSK1120212 Food-effect StudyCompletedNCT01371487Phase 1
- First International Randomized Study in Malignant Progressive Pheochromocytoma and ParagangliomaCompletedNCT01371201Phase 2
- MK-2206 in Recurrent Nasopharyngeal CarcinomaCompletedNCT01370070Phase 2
- Study of Oral AMN107 (Nilotinib) in Adult Patients With Imatinib - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase Previously Enrolled to CAMN107A2109 TrialCompletedNCT01368523Phase 4
- A Study of ARRY-371797 in Patients With Osteoarthritis of the KneeCompletedNCT01366014Phase 2
- Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Mycophenolate Mofetil in Healthy VolunteersCompletedNCT01364987Phase 1
- A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015KCompletedNCT01364974Phase 1
- Safety and Tolerability of DS-7423 in Subjects With Advanced Solid Malignant TumorsCompletedNCT01364844Phase 1
- Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid MalignanciesActive, not recruitingNCT01364051Phase 1
- A Phase 1 Study to Evaluate the Effect of Rifampin on the Pharmacokinetics of Tivozanib in Healthy SubjectsCompletedNCT01363804Phase 1
- A Phase 1 Study to Evaluate The Effect of Ketoconazole on the Pharmacokinetics of Tivozanib in Healthy SubjectsCompletedNCT01363778Phase 1
- A Study Looking at Kidney Function in Kidney Transplant Recipients Who Are Taking Anti-rejection Medication Including Tacrolimus and With or Without Sirolimus.CompletedNCT01363752Phase 4
- Assess the Efficacy of Whole Brain Radiation Therapy in Lung Cancer Patients With Brain MetastasisTerminatedNCT01363557Not applicable
- Safety, Pharmacokinetics and Pharmacodynamics of BKM120 Plus MEK162 in Selected Advanced Solid Tumor PatientsCompletedNCT01363232Phase 1
- AZD6244 Hydrogen Sulfate for Children With Nervous System TumorsActive, not recruitingNCT01362803Phase 1/2
- TRICC-C (AIO-KRK-0111): BIBF 1120 Versus Placebo in Patients Receiving Oxaliplatin Plus Fluorouracil and Leucovorin (mFOLFOX6) for Advanced, Chemorefractory Metastatic Colorectal Cancer (mCRC)CompletedNCT01362361Phase 2
- Pilot Clinical Trial of Pazopanib in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or at Initial Diagnosis When no Intensive Treatment is PossibleCompletedNCT01361334Phase 2
- A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory Solid Tumors or LymphomaCompletedNCT01359696Phase 1
- Palliative Treatment of Hepatocellular Carcinoma in Patient With CHILD B CirrhosisCompletedNCT01357486Phase 2
- A Phase 2, Open-Label Study of Amuvatinib in Combination With Platinum-Etoposide Chemotherapy in Small Cell Lung CancerCompletedNCT01357395Phase 2
- Oral SAR245408 (XL147) and Oral MSC1936369B in Patients With Locally Advanced or Metastatic Solid TumorsCompletedNCT01357330Phase 1
- Evaluating the Safety and Tolerability of GDC-0349 in Patients With Locally Advanced or Metastatic Solid Tumors or Non Hodgkin's LymphomaCompletedNCT01356173Phase 1
- Effects of Administration of Fostamatinib on Blood Concentrations of Digoxin in Healthy SubjectsCompletedNCT01355354Phase 1
- AZD1152 in Diffuse Large B-cell LymphomaCompletedNCT01354392Phase 1/2
- Efficacy and Safety of Induction Strategies Combined With Low Tacrolimus Exposure in Kidney Transplant Recipients Receiving Everolimus or Sodium MycophenolateCompletedNCT01354301Phase 4
- Open Label Phase 1 Study in Japan for Patient With Advanced Solid MalignanciesCompletedNCT01353781Phase 1
- Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.CompletedNCT01353625Phase 1
- Hepatocellular Carcinoma (HCC) Transarterial Chemoembolisation (TACE) +AxitinibCompletedNCT01352728Phase 2
- MEK162 and RAF265 in Adult Patients With Advanced Solid Tumors Harboring RAS or BRAFV600E MutationsCompletedNCT01352273Phase 1
- Escalating Dose Study in Subjects With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, and Waldenstrom's MacroglobulinemiaCompletedNCT01351935Phase 1
- BIBF 1120 and RAD001 in Solid Tumors - Phase ICompletedNCT01349296Phase 1
- Investigational Drug in Combination With Two Chemotherapy Drugs in Women With Locally Recurrent or Metastatic Breast CancerWithdrawnNCT01349088Phase 1/2
- Lenalidomide in Combination With a Fixed Dose of Sorafenib for the Treatment of Hepatocellular CarcinomaTerminatedNCT01348503Phase 1
- Study of RAD001 for Treatment of NF2-related Vestibular SchwannomaTerminatedNCT01345136Phase 2
- Study of PI3 Kinase/mTOR Inhibitor BEZ235 Twice Daily for Advanced Solid TumorsCompletedNCT01343498Phase 1
- A Study of Complete Molecular Response for Chronic Myeloid Leukemia in Chronic Phase Patients, Treated With DasatinibCompletedNCT01342679Phase 2
- Sorafenib in Elderly Patients With Metastatic Renal Cell CarcinomaTerminatedNCT01342627Phase 2
- Safety and Tolerability Study of RAD001 and LBH589 in All Solid Tumors With Enrichment for EBV Driven TumorsStatus unknownNCT01341834Phase 1
- A Pharmacokinetics Study of the Effects of GSK2118436 on Warfarin, the Effects of Ketoconazole and Gemfibrozil on GSK2118436, and the Effects of Repeat Doses of GSK2118436 in Subjects With BRAF Mutant Solid TumorsCompletedNCT01340846Phase 1
- Determination of the Absolute Bioavailability of GSK2118436 Following a Single Oral Dose Co-Administered With an Intravenous Radiolabelled Microtracer of GSK2118436 in Subjects With BRAF Mutant Solid TumorsCompletedNCT01340833Phase 1
- Study of Pazopanib and Vorinostat in Patients With Advanced MalignanciesCompletedNCT01339871Phase 1
- BKM120 and Fulvestrant for Treating Postmenopausal Patients With Estrogen Receptor-Positive Stage IV Breast CancerCompletedNCT01339442Phase 1
- Open Label Regorafenib Study to Evaluate Cardiovascular Safety Parameters, Tolerability, and Anti-tumor ActivityCompletedNCT01339104Phase 1
- Safety, Pharmacokinetics and Pharmacodynamics of BEZ235 Plus MEK162 in Selected Advanced Solid Tumor PatientsCompletedNCT01337765Phase 1
- Pilot Study Sorafenib as Bridge to Orthotopic Liver Transplantation (OLT)TerminatedNCT01337492Early Phase 1
- Efficacy and Safety of Ursodeoxycholic Acid (UDCA) Added to the DPP-4 Inhibitor in People With Type 2 Diabetes and Chronic Liver DiseasesStatus unknownNCT01337440Phase 4
- A Trial of Cediranib in the Treatment of Patients With Alveolar Soft Part Sarcoma (CASPS)Status unknownNCT01337401Phase 2
- GLPG0778: Multiple Ascending Oral Doses, Pharmacokinetic, Safety, and Pharmacodynamic StudyCompletedNCT01336244Phase 1