Protein Kinase Inhibitors: all 15,278 studies that test it
Page 120 of 153. Open to participants first (2,558), then studies with results posted, then the rest; newest registration first within each.
- Phase I Study of Sulfatinib(HMPL-012) in Patients With Advanced Solid TumorsCompletedNCT02133157Phase 1
- Ruxolitinib Phosphate in Reducing Fatigue in Patients With Chronic Lymphocytic LeukemiaActive, not recruitingNCT02131584Phase 2
- A Study of Lapatinib in Combination With Caelyx in Patients With Advanced HER2 Positive Pretreated Breast CancerTerminatedNCT02131506Phase 1
- Effect of Adjuvant Therapy by Sorafenib, Oxaliplatin and S-1WithdrawnNCT02129322Phase 2
- Explore the Synergy of Combination TKI TherapyWithdrawnNCT02129166Phase 1
- Study of CX-4945 in Combination With Gemcitabine and Cisplatin for Frontline Treatment of CholangiocarcinomaCompletedNCT02128282Phase 1/2
- Auranofin and Sirolimus in Treating Patients With Advanced Solid Tumors or Recurrent Non-Small Cell Lung CancerWithdrawnNCT02126527Phase 1
- Icotinib Versus Placebo as Adjuvant Therapy in EGFR-mutant Lung AdenocarcinomaStatus unknownNCT02125240Phase 3
- Enzalutamide Plus Everolimus in Men With Metastatic Castrate-Resistant Prostate CancerCompletedNCT02125084Phase 1
- A Study to Test the Safety of the Investigational Drug Larotrectinib in Adults That May Treat CancerCompletedNCT02122913Phase 1
- Phase I Study of Chiauranib in Patients With Advanced Solid TumorsCompletedNCT02122809Phase 1
- Second Line Sorafenib After Pazopanib in Patients With RCCTerminatedNCT02122003Phase 2
- Open Label Phase I/Randomised,Double Blind Phase II Study in mCRPC of AZD5363 In Combination With DP ChemotherapyCompletedNCT02121639Phase 1/2
- Copanlisib Mass Balance StudyCompletedNCT02119221Phase 1
- Phase I BKM120/Abraxane in Solid Tumors, Expansion Phase Recurrent Endometrial or Ovarian CancerWithdrawnNCT02117817Phase 1
- Calcineurin Inhibitor Based Immunosuppression WithdrawalCompletedNCT02117596Not applicable
- Clinical Study of Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)SuspendedNCT02117336Phase 1
- SAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC PatientsCompletedNCT02117167Phase 2
- The Tolerability of Saracatinib in Subjects With Lymphangioleiomyomatosis (LAM) (SLAM-1)CompletedNCT02116712Phase 1
- A Single Agent Study to Evaluate the Overall Response Rate, Safety and Tolerability of Orally Administered VemurafenibWithdrawnNCT02115035Phase 1/2
- Sorafenib Phase II Study for Japanese Anaplastic or Medullary Thyroid Carcinoma PatientsCompletedNCT02114658Phase 2
- Phase 2 Study of Alisertib Therapy for Rhabdoid TumorsActive, not recruitingNCT02114229Phase 2
- Pazopanib for Metastatic Alveolar Soft Part SarcomaTerminatedNCT02113826Phase 2
- A Dose Escalation Study of ASP8273 in Subjects With Non-Small-Cell Lung Cancer (NSCLC) Who Have Epidermal Growth Factor Receptor (EGFR) MutationsCompletedNCT02113813Phase 1
- Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II StudyCompletedNCT02113800Phase 2
- Study to Assess Dasatinib in Patients With Core Binding Factors Acute Myelogenous LeukemiaCompletedNCT02113319Phase 2
- A Study to Evaluate the Effect of Verapamil on the Pharmacokinetics of ASP015K in Healthy Adult SubjectsCompletedNCT02111317Phase 1
- First-in-human Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of CC-90001CompletedNCT02110420Phase 1
- A Phase 1b/2a Study Evaluating AMG 232 in Metastatic MelanomaCompletedNCT02110355Phase 1
- Analysis of Tumor Tissue and Circulating Genetic Material in the Blood to Obtain Further Insight in the Effectiveness of Everolimus When Combined With ExemestaneStatus unknownNCT02109913Not applicable
- Efficacy and Safety of LGX818 in Patients With Advanced or Metastatic BRAF V600 Mutant NSCLCWithdrawnNCT02109653Phase 2
- Alisertib in Chemotherapy-pretreated Urothelial CancerCompletedNCT02109328Phase 2
- Ibrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With HIV InfectionTerminatedNCT02109224Phase 1
- A Study to Assess the Efficacy and Safety of the VEGFR-FGFR Inhibitor, Lucitanib, Given to Patients With Advanced/Metastatic Lung Cancer and FGF, VEGF, or PDGF Related Genetic AlterationsTerminatedNCT02109016Phase 2
- Dovitinib Lactate in Treating Patients With Pancreatic Neuroendocrine TumorsWithdrawnNCT02108782Phase 2
- Effect of Regorafenib on Digoxin and Rosuvastatin in Patients With Advanced Solid Malignant Tumors.CompletedNCT02106845Phase 1
- ARN 509 Plus Everolimus in Men With Progressive Metastatic Castration-Resistant Prostate Cancer After Treatment With Abiraterone AcetateCompletedNCT02106507Phase 1
- A Study of MEK162 With Gemcitabine and Oxaliplatin in Biliary CancerWithdrawnNCT02105350Phase 1
- A Study of the Safety, Tolerability and Pharmacokinetics of HMPL-523CompletedNCT02105129Phase 1
- Comparative Bioequivalence Study in Adult Patients Suffering From Chronic Myeloid Leukemia & Gastrointestinal Stromal Tumor Under Fed ConditionsCompletedNCT02103322Phase 2/3
- Drug Interaction Study Between Bosutinib And DabigatranCompletedNCT02102633Phase 1
- Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade GliomaCompletedNCT02101905Phase 1
- TGR-1202, a PI3K Delta Inhibitor, in Combination With Obinutuzumab and Chlorambucil in Patients With Chronic Lymphocytic Leukemia (CLL)CompletedNCT02100852Phase 1
- Study of Oral RXDX-101 in Adult Patients With Locally Advanced or Metastatic Cancer Targeting NTRK1, NTRK2, NTRK3, ROS1, or ALK Molecular Alterations.CompletedNCT02097810Phase 1
- Dacomitinib (PF-00299804) Pharmacokinetics In Chinese Healthy VolunteersCompletedNCT02097433Phase 1
- A Phase 1/2 Study Evaluating AMG 337 in Asian SubjectsCompletedNCT02096666Phase 1/2
- Duvelisib in Hepatically Impaired Subjects Compared to Healthy SubjectsCompletedNCT02095587Phase 1
- Regorafenib and Cetuximab in Patients With Advanced MalignancyCompletedNCT02095054Phase 1
- To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male VolunteersCompletedNCT02093728Phase 1
- POEM STUDY: A Phase IIa Trial in Endometrial Carcinoma With TemsirolimusCompletedNCT02093598Phase 2
- Randomized Open-Label Study of INCB047986 in Subjects With Primary Myelodysplastic Syndrome (MDS)TerminatedNCT02093429Phase 1/2
- A Study of the Effect of Formulation and Tablet Hardness on the Bioavailability of Pictilisib in Healthy VolunteersCompletedNCT02092831Phase 1
- MicroRNA Expression in Everolimus-based Versus Tacrolimus-based Regimens in Kidney TransplantationStatus unknownNCT02091973Not applicable
- Optimizing Pazopanib Exposure in RCC PatientsTerminatedNCT02089802Phase 2
- Study of LEE011 With Fulvestrant and BYL719 or BKM120 in Advanced Breast CancerCompletedNCT02088684Phase 1
- Efficacy and Safety Assessment of NIlotinib in CML Patients With Suboptimal Response on Imatinib TherapyTerminatedNCT02086487Phase 4
- SarCaBon: A Randomised Phase II Trial of Saracatinib Versus Placebo for Cancer-induced Bone PainCompletedNCT02085603Phase 2
- Study Of Palbociclib (PD-0332991) In Renal ImpairmentCompletedNCT02085538Phase 1
- A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard TherapyCompletedNCT02085148Phase 1
- Safety and Efficacy of Sorafenib in Patients With Advanced Thyroid Cancer: a Phase II Clinical StudyCompletedNCT02084732Phase 2
- Everolimus + Very Low Tacrolimus vs Enteric-coated Mycophenolate Sodium + Low Tacrolimus in de Novo Renal TransplantCompletedNCT02084446Phase 4
- Study to Evaluate GLPG0634 in Subjects With Renal Impairment Compared to Healthy SubjectsCompletedNCT02084199Phase 1
- Effects of Dabrafenib on the Single Dose Pharmacokinetics (PK) of Rosuvastatin and MidazolamCompletedNCT02082665Phase 1
- A Phase I Study of Oral Asciminib (ABL001) in Patients With CML or Ph+ ALLCompletedNCT02081378Phase 1
- Efficacy and Safety Study of Topical Rapamycin Associated With Pulsed Dye Laser in Patients With Sturge-Weber SyndromeCompletedNCT02080624Phase 2
- A Phase I Dose Escalation Study of Erlotinib in Combination With TheophyllineTerminatedNCT02080078Phase 1
- A Safety and Efficacy Study of LGH447 in Patients With Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)CompletedNCT02078609Phase 1
- Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic TumorsCompletedNCT02077933Phase 1
- AKT Inhibitor in Oestrogen Positive Breast CancerCompletedNCT02077569Phase 2
- Effect of Everolimus on the Pharmacokinetics of Tacrolimus in Renal Transplant PatientsCompletedNCT02077556Phase 4
- Study of Combination Ruxolitinib and Decitabine Treatment for Accelerated Phase MPN or Post-MPN AMLCompletedNCT02076191Phase 1/2
- CRIZENT: Crizotinib and Sunitinib in Metastatic Breast CancerTerminatedNCT02074878Phase 1
- T-DM1 With Abraxane and Lapatinib for Metastatic HER2 Positive Breast CancerCompletedNCT02073916Phase 1
- Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by SurgeryCompletedNCT02072486Not applicable
- Study of Ruxolitinib in the Treatment of Cachexia in Patients With Tumor-Associated Chronic Wasting Diseases.TerminatedNCT02072057Phase 2
- Phase II Study of Anlotinib in Patients With Advanced Renal Cell Carcinoma That Have Failed Or Are Intolerant To TKIs TherapyStatus unknownNCT02072044Phase 2
- Phase II Study of Anlotinib Versus Sunitinib in Patients With Advanced Renal Cell Carcinoma（RCC）Status unknownNCT02072031Phase 2
- PLX3397 KIT in Acral aNd mucOsal MelanomaCompletedNCT02071940Phase 2
- Phase II Study of Sunitinib Rechallenge in Patients With Metastatic Renal Cell CarcinomaTerminatedNCT02071641Phase 2
- Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic DysfunctionCompletedNCT02070549Phase 1
- A Study of Drug Therapies for Salivary Gland Cancers Based on Testing of GenesCompletedNCT02069730Not applicable
- Dose Finding Study Of PF-05212384 With Paclitaxel And Carboplatin In Patients With Advanced Solid TumorCompletedNCT02069158Phase 1
- Dose Escalation Study of OMP-54F28 in Combination With Sorafenib in Patients With Hepatocellular CancerCompletedNCT02069145Phase 1
- Pharmacokinetic Comparison of XS003 and TasignaCompletedNCT02068898Phase 1
- Sunitinib Malate or Valproic Acid in Preventing Metastasis in Patients With High-Risk Uveal MelanomaActive, not recruitingNCT02068586Phase 2
- A Pilot Study of Trientine With Vemurafenib for the Treatment BRAF Mutated Metastatic MelanomaWithdrawnNCT02068079Phase 1
- Icotinib and Arsenic Trioxide in Treating Non-small-cell Lung Cancer Patients With Resistance to EGFR-TKIStatus unknownNCT02066870Phase 1
- Trial of Pazopanib in Patients With Solitary Fibrous Tumor and Extraskeletal Myxoid ChondrosarcomaCompletedNCT02066285Phase 2
- Intermittent and Maintenance of Erlotinib in Combination With Pemetrexed/Carboplatin in Ⅲb/IV Non Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) MutationStatus unknownNCT02066038Phase 2
- A Study of Dovitinib With Androgen Deprivation Therapy (ADT) in Patients With Metastatic Prostate Cancer Receiving Primary ADTWithdrawnNCT02065323Phase 2
- A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Anti-Cancer Activity of Trametinib in Combination With Palbociclib in Subjects With Solid TumorsCompletedNCT02065063Phase 1
- Investigating the Effects of AZD2014 Therapy Given Prior to Radical Prostatectomy in Men With High Risk Prostate CancerCompletedNCT02064608Phase 1
- Erlotinib Treatment Beyond Progression in EGFR Mutant NSCLCCompletedNCT02064491Phase 2
- A Study Evaluating the Effect of Formulation on the Bioavailability of Ipatasertib in Healthy VolunteersCompletedNCT02063581Phase 1
- To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Renal Impaired Subjects and Healthy SubjectsCompletedNCT02063204Phase 1
- Differentiating Everolimus Versus Sirolimus in Combination With Calcineurin Inhibitors in Kidney Transplant PatientsWithdrawnNCT02062892Phase 4
- Icotinib in Advanced Non-small Cell Lung Cancer (NSCLC) With Hepatic InsufficiencyStatus unknownNCT02062515Phase 2
- A Study To Investigate Palbociclib (PD-0332991) Pharmacokinetics In Healthy Subjects Of Japanese Descent Relative To Healthy Non-Asian Subjects, And To Determine If Changes In Palbociclib Dose Result In Proportional Changes In Palbociclib Plasma Exposure In Japanese SubjectsCompletedNCT02059330Phase 1
- Study of High-dose, Intermittent Sunitinib in Patients With Solid Tumors.CompletedNCT02058901Phase 1
- A Phase Ib Dose De-escalation Study With BYL719 in Premenopausal Patients With Locally Advanced or Metastatic Breast CancerCompletedNCT02058381Phase 1