Protein Kinase Inhibitors: all 15,278 studies that test it
Page 122 of 153. Open to participants first (2,558), then studies with results posted, then the rest; newest registration first within each.
- A Study of LY2801653 in Healthy ParticipantsCompletedNCT01981408Phase 1
- A Study of the Elimination, Pharmacokinetics, and Metabolism of RO5424802CompletedNCT01981005Phase 1
- A Study to Evaluate the Effect of Particle Size, Formulation and Food on the Pharmacokinetics of GDC-0032 in Healthy VolunteersCompletedNCT01980953Phase 1
- Phase Ib/II Study of LY2780301 in Combination With Weekly PACLITAXEL in HER2-metastatic Breast CancerTerminatedNCT01980277Phase 1/2
- IRCI Gynae Sarcomas, High Grade Uterine SarcomaCompletedNCT01979393Phase 2
- Gossypol Combined With Docetaxel and Cisplatin Scheme in Advanced Non Small-cell Lung Cancers With APE1 High ExpressionStatus unknownNCT01977209Phase 3
- Phase 1b Study of PD-0332991 in Combination With T-DM1(Trastuzumab-DM1)CompletedNCT01976169Phase 1
- Efficacy and Safety Study of CC-292 Versus Placebo as Co-therapy With Methotrexate in Active Rheumatoid ArthritisCompletedNCT01975610Phase 2
- A Phase Ib Study of Fruquintinib in 3rd Line mCRCCompletedNCT01975077Phase 1/2
- To Assess the Effect of Food on the Pharmacokinetics of Selumetinib (AZD6244; ARRY-142886) (Hyd-Sulfate) in Healthy Male VolunteersCompletedNCT01974349Phase 1
- The Preventative and Therapeutical Effect of Ursodeoxycholic Acid(UDCA) to Short Bowel Syndrome PatientsCompletedNCT01974336Phase 4
- Safety, Tolerability, and Pharmacokinetics of Onartuzumab Combined With Vemurafenib and/or Cobimetinib in Cancer PatientsWithdrawnNCT01974258Phase 1
- Safety and Pharmacokinetics of Regorafenib and Cetuximab in CombinationCompletedNCT01973868Phase 1
- Study of Icotinib Hydrochloride in Treating Patients With Recurrent or Metastatic Esophageal Cancer After Failure of Conventional ChemotherapyCompletedNCT01973725Phase 2
- PAM50 HER2-enriched Phenotype as a Predictor of Response to Dual HER2 Blockade in HER2-positive Early Breast CancerCompletedNCT01973660Phase 2
- Dovitinib (TKI258) in the Treatment of Patients With Relapsed GlioblastomaStatus unknownNCT01972750Phase 1
- Neoadjuvant Dabrafenib + Trametinib for AJCC Stage IIIB-C BRAF V600 Mutation Positive MelanomaCompletedNCT01972347Phase 2
- First-in-Human Dose Escalation Trial in Subjects With Advanced MalignanciesCompletedNCT01971515Phase 1
- Buparlisib, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid TumorsWithdrawnNCT01971489Phase 1
- A Pharmacokinetic Study in Healthy Participants to Assess the Pharmacokinetics and Safety of a Supratherapeutic Dose of PCI-32765 (Ibrutinib) Capsule and Solution Formulations Administered With FoodCompletedNCT01969266Phase 1
- A Bioavailability and Pharmacokinetic Study of GDC-0032 in Healthy VolunteersCompletedNCT01967966Phase 1
- Low Dose Daily Erlotinib in Combination With High Dose Twice Weekly Erlotinib in Patients With EGFR-Mutant Lung CancerCompletedNCT01967095Phase 1
- A Study of LY2157299 in Healthy ParticipantsCompletedNCT01965808Phase 1
- Pilot Study of Ruxolitinib in Relapsed or Refractory Hodgkin Lymphoma and Primary Mediastinal Large B-cell LymphomaCompletedNCT01965119Phase 2
- A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-38877618 in Healthy Male ParticipantsCompletedNCT01964872Phase 1
- Study of Efficacy and Safety INC280 in Patients With Advanced Hepatocellular CarcinomaWithdrawnNCT01964235Phase 2
- An Open-label, Multicenter, Phase II Study of LDK378 in Patients With Non-small Cell Lung Cancer Harboring ROS1 RearrangementCompletedNCT01964157Phase 2
- An Open-label, Multicenter, Phase II Study of Dovitinib in Advanced Thyroid CancerCompletedNCT01964144Phase 2
- Evaluation of the High Dose of Icotinib in Advanced Lung Cancer Patients After Failure of Target TherapyStatus unknownNCT01963195Phase 2
- A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Patients With Advanced or Refractory Solid Tumors or LymphomaCompletedNCT01962532Phase 1
- Phase I Trial of Cabozantinib in Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT01961765Phase 1
- Everolimus in Selected Patients With Metastatic Melanoma: Efficacy and Safety StudyStatus unknownNCT01960829Phase 2
- Dose-escalation Study to Assess Selumetinib Safety, Tolerability and PKCompletedNCT01960374Phase 1
- Safety and Efficacy Study of Neratinib and Cetuximab to Treat Patients With Quadruple Wild-Type Metastatic Colorectal CancerWithdrawnNCT01960023Phase 1/2
- Vemurafenib Plus Cobimetinib Plus PEG-interferon in Advanced Melanoma Patients Harboring the V600BRAF MutationCompletedNCT01959633Phase 1/2
- Drug-Drug Interaction Study Evaluating Effects of ASP015K on RosuvastatinCompletedNCT01959399Phase 1
- A Study of Safety and Effectiveness of JNJ-54781532 in Patients With Moderately to Severely Active Ulcerative ColitisCompletedNCT01959282Phase 2
- Study Comparing in Livertransplantation Recipients With Tacrolimus Alone Versus Tacrolimus&SirolimusCompletedNCT01958190Phase 4
- Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin LymphomaActive, not recruitingNCT01955499Phase 1
- Erlotinib 100mg qd Versus Gefitinib 250mg qd for EGFR Mutant NsclcStatus unknownNCT01955421Phase 2
- Food Effect Study of Single Dose of Fruquintinib (HMPL-013) in Healthy SubjectsCompletedNCT01955304Phase 1
- A Study of Everolimus in the Treatment of Neurocognitive Problems in Tuberous SclerosisStatus unknownNCT01954693Phase 2
- A Study of CFI-400945 Fumarate in Patients With Advanced CancerCompletedNCT01954316Phase 1
- A Pharmacokinetics (PK) Study of the Effects Rabeprazole and Rifampin on Dabrafenib in Subjects With BRAF V600 Mutation Positive TumorsCompletedNCT01954043Phase 1
- A Two-part Study to Investigate the Interaction and Pharmacokinetics of GSK2586184CompletedNCT01953835Phase 1
- A Study To Investigate The Drug-Drug Interaction Potential Of Rifampin OnThe Investigational Agent Palbociclib (PD-0332991)CompletedNCT01953731Phase 1
- Paclitaxel and BKM120 Before Surgery in Treating Patients With Stage II or III Estrogen Receptor-Positive and HER2-Negative Breast CancerWithdrawnNCT01953445Phase 2
- To Determine the Maximum Tolerated Dose (MTD) of BIBF 1120 in Patients With Solid TumoursCompletedNCT01951846Phase 1
- Phase II Study of VS-6063 in Patients With KRAS Mutant Non-Small Cell Lung CancerCompletedNCT01951690Phase 2
- To Determine the Relative Bioavailability of Different Formulations of AZD9291 and the Effect of Food.CompletedNCT01951599Phase 1
- Gefitinib With or Without Chemotherapy in Brain Metastases From Non-small Cell Lung CancerStatus unknownNCT01951469Phase 3
- Effect of Hepatic Impairment on LDK378 PharmacokineticsCompletedNCT01950481Phase 1
- Study to Determine the Efficacy of Regorafenib in Metastatic Colorectal Cancer Patients and to Discover BiomarkersStatus unknownNCT01949194Phase 2
- Debio 1347-101 Phase I Trial in Advanced Solid Tumours With Fibroblast Growth Factor Receptor (FGFR) AlterationsTerminatedNCT01948297Phase 1
- Phase 1 Study in Healthy Subjects to Evaluate the Effect of Rifampin on the Pharmacokinetics of IPI-145CompletedNCT01947777Phase 1
- Dabrafenib and Lapatinib in Treating Patients With Refractory Thyroid Cancer That Cannot Be Removed by SurgeryActive, not recruitingNCT01947023Phase 1
- A Study of the Safety and Pharmacokinetics of SAR245408 Tablets in Patients With Solid Tumors or LymphomaCompletedNCT01943838Phase 1
- Safety and Efficacy Study of Vemurafenib and High-dose Interferon Alfa-2b in MelanomaCompletedNCT01943422Phase 1
- Phase I Trial of Vandetanib Combined With 131I-mIBG to Treat Patients With Advanced Phaeochromocytoma and ParagangliomaWithdrawnNCT01941849Phase 1
- A Study to Investigate Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of PQR309CompletedNCT01940133Phase 1
- Phase Ib/II Trials of RAD001 in Triple Negative Metastatic Breast CancerTerminatedNCT01939418Phase 1/2
- Open Label Phase I Dose Escalation Study With BAY1143572 in Patients With Advanced CancerCompletedNCT01938638Phase 1
- Safety and Tolerability of Trametinib in Combination With Docetaxel in Japanese Subjects With Non-small Cell Lung CancerWithdrawnNCT01938456Phase 1
- A Dose Escalation Study to Assess Safety of GSK2256098 (FAK Inhibitor) in Combination With Trametinib (MEK Inhibitor) in Subjects With Advanced Solid TumorsCompletedNCT01938443Phase 1
- Study of Pyrotinib in Patients With Human Epidermalgrowth Factor Receptor 2 (HER2) Positive Advanced Breast CancerCompletedNCT01937689Phase 1
- Study to Investigate the Effect of a Single Dose of AZD7624 on Inflammation Caused by an Endotoxin ChallengeCompletedNCT01937338Phase 1
- Trametinib With or Without GSK2141795 in Treating Patients With Recurrent or Persistent Endometrial CancerCompletedNCT01935973Phase 1
- A Clinical Trial of Safety and Efficacy of Fasudil in Subjects With Amyotrophic Lateral Sclerosis (ALS)Status unknownNCT01935518Phase 2
- Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma MultiformeCompletedNCT01934361Phase 1
- Third-line Treatment of Gefitinib in NSCLC PatientsCompletedNCT01933347Phase 2
- Sorafenib in Liver Function Impaired Advanced Hepatocellular CarcinomaCompletedNCT01932385Phase 2/3
- A Phase Ib Study of Selatinib Ditosilate Tablets in Patients With Advanced Breast CancerStatus unknownNCT01931943Phase 1
- Study Evaluating Absorption, Distribution, Metabolism and Excretion (ADME) of Single Dose [14C] Selumetinib in VolunteersCompletedNCT01931761Phase 1
- Safety Study of Two Oral Formulations of MGCD265 Administered in Healthy Subjects in the Fasting StateCompletedNCT01930006Phase 1
- An Open-Label Study of a Novel JAK-inhibitor, INCB047986, Given in Patients With Advanced MalignanciesTerminatedNCT01929941Phase 1
- Regorafenib Assessment in Refractory Advanced Colorectal Cancer(RegARd-C)CompletedNCT01929616Phase 2
- A Study to Assess the Relative Bioavailability Between Two ASP015K Tablets and the Food Effect of a New Tablet in Healthy Adult SubjectsCompletedNCT01929577Phase 1
- Icotinib as Adjuvant Therapy in Treating Non-small-cell Lung Cancer Patients With Positive EGFR MutationStatus unknownNCT01929200Phase 2
- Phase 1b Trial of BGJ398/BYL719 in Solid TumorsCompletedNCT01928459Phase 1
- Evaluation of Early Use of Everolimus (EVE) on Cytomegalovirus (CMV) Infection in Renal Transplant RecipientsStatus unknownNCT01927588Phase 4
- Icotinib With Whole Brain Radiation Therapy in NSCLC Patients With Brain MetastasesStatus unknownNCT01926171Phase 4
- Phase 1 Study in Healthy Subjects to Evaluate the Effect of IPI-145 on the Pharmacokinetics of MidazolamCompletedNCT01925911Phase 1
- Alisertib and Gemcitabine Hydrochloride in Treating Patients With Solid Tumors or Pancreatic CancerCompletedNCT01924260Phase 1
- Phase II Study of Anlotinib in Patients With Advanced Non-small Cell Lung Cancer（ALTER0302）CompletedNCT01924195Phase 2
- Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal CancerCompletedNCT01923337Phase 1
- To Determine the Maximum Tolerated Dose of Oral CEP-37440 in Patients With Advanced or Metastatic Solid TumorsCompletedNCT01922752Phase 1
- Dovitinib Plus Docetaxel in Gastric CancerCompletedNCT01921673Phase 1/2
- ARRY-380 + Trastuzuamab for Breast w/ Brain MetsCompletedNCT01921335Phase 1
- Midostaurin in Indolent Systemic MastocytosisStatus unknownNCT01920204Phase 2
- Dual Targeting of EGFR With Cetuximab and Afatinib to Treat Refractory wtKRAS Metastatic Colorectal CancerCompletedNCT01919879Phase 2
- Drug Interaction Study To Investigate The Potential Effect Of Proton Pump Inhibitor On The Pharmacokinetics Of Palbociclib (PD-0332991)CompletedNCT01918176Phase 1
- OPTIM DASATINIB (Optimized Tyrosine Kinase Inhibitors Monotherapy)CompletedNCT01916785Phase 2
- Refametinib in Combination With Sorafenib in RAS Mutant Hepatocellular Carcinoma (HCC)CompletedNCT01915602Phase 2
- Refametinib(BAY86-9766) in RAS Mutant Hepatocellular Carcinoma (HCC)CompletedNCT01915589Phase 2
- Phase I Dose Escalation Study With an Allosteric AKT 1/2 Inhibitor in PatientsCompletedNCT01915576Phase 1
- Phase I/II Study of Nilotinib/Ruxolitinb Therapy for TKI Resistant Ph-LeukemiaCompletedNCT01914484Phase 1/2
- Trametinib, Combination Chemotherapy, and Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by SurgeryTerminatedNCT01912625Phase 1
- INC280 and Erlotinib Hydrochloride in Treating Patients With Non-small Cell Lung CancerCompletedNCT01911507Phase 1
- Phase II Study of Buparlisib + Docetaxel in Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) PatientsTerminatedNCT01911325Phase 1
- Dabrafenib in Treating Patients With Solid Tumors and Kidney or Liver DysfunctionTerminatedNCT01907802Phase 1