Protein Kinase Inhibitors: all 15,278 studies that test it
Page 106 of 153. Open to participants first (2,556), then studies with results posted, then the rest; newest registration first within each.
- Secondary Prevention Trial of Rapamycin in Patients With Resected Non-muscle Invasive Bladder CancerWithdrawnNCT03298958Phase 3
- Apatinib Plus Etoposide Versus Etoposide Alone for Platinum-resistant Recurrent Ovarian CancerStatus unknownNCT03298074Phase 2
- M7583 Relative Bioavailability of Tablet Compared to Powder-in-capsuleCompletedNCT03297983Phase 1
- Ribociclib + PDR001 in Breast Cancer and Ovarian CancerTerminatedNCT03294694Phase 1
- Merestinib on Bone Metastases in Subjects With Breast CancerTerminatedNCT03292536Phase 1
- Korean Cancer Study Group: Translational bIomarker Driven UMbrella Project for Head and Neck (TRIUMPH), Esophageal Squamous Cell Carcinoma- Part 1 (HNSCC)]CompletedNCT03292250Phase 2
- Clinical Trial on the Combination of Avelumab and Axitinib for the Treatment of Patients With Recurrent GlioblastomaCompletedNCT03291314Phase 2
- A Study to Investigate the Effect of Formulation, Food, and Rabeprazole on the Pharmacokinetics (PK) of GDC-0853 in Healthy ParticipantsCompletedNCT03290703Phase 1
- Trial of Taselisib in OvergrowthTerminatedNCT03290092Phase 1/2
- Ruxolitinib + Allogeneic Stem Cell Transplantation in AMLActive, not recruitingNCT03286530Phase 2
- Second-line CM082 Combined With Paclitaxel For Patients With Advanced Gastric CancerStatus unknownNCT03286244Phase 1
- An Exploratory Clinical Study of Apatinib for the 2nd Treatment of Esophageal Cancer or Esophageal and GastricStatus unknownNCT03285906Phase 2/3
- Treatment Plan for an Individual Patient With Recurrent Uterine Papillary Serous Carcinoma (UPSC) With PIK3CA Gene MutationCompletedNCT03285802Phase 2/3
- CDK 4/6 Inhibitor, Ribociclib, With Adjuvant Endocrine Therapy for ER-positive Breast CancerActive, not recruitingNCT03285412Phase 2
- HM95573 in Combination With Either Cobimetinib or Cetuximab in Patients With Locally Advanced or Metastatic Solid TumorsActive, not recruitingNCT03284502Phase 1
- Testing AZD1775 in Advanced Solid Tumors That Have a Mutation Called SETD2Active, not recruitingNCT03284385Phase 2
- Tailoring NEOadjuvant Therapy in Hormone Receptor Positive, HER2 Negative, Luminal Breast Cancer.Active, not recruitingNCT03283384Phase 2
- Combination of Pembrolizumab With TGR-1202 in Patients With Relapsed/Refractory CLL and B-cell NHLActive, not recruitingNCT03283137Phase 1
- Nintedanib in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome Grade 0p-1-2CompletedNCT03283007Phase 3
- Ibrutinib in Treating Participants With Untreated High Risk Smoldering Mantle Cell LymphomaActive, not recruitingNCT03282396Phase 2
- Protocol GELLC-7: Ibrutinib Followed by Ibrutinib Consolidation in Combination With OfatumumabStatus unknownNCT03280160Phase 2
- Study Evaluating the Efficacy of Maintenance Olaparib and Cediranib or Olaparib Alone in Ovarian Cancer PatientsStatus unknownNCT03278717Phase 3
- Apatinib in Combination With S-1 as Second-Line Treatment in Patients With Advanced Gastric CancerStatus unknownNCT03276156Phase 1
- Clinical Trial of the Use of the Nasal Spray of Patients With Recurrence of GlioblastomaWithdrawnNCT03275558Phase 1
- Effect of Ruxolitinib on Tumor Infiltrating Myeloid CellsWithdrawnNCT03274778Not applicable
- Efficacy and Safety of Apatinib for Recurrent or Metastatic Esophageal Squamous Cell CarcinomaCompletedNCT03274011Phase 2
- Lapatinib Plus Chemotherapy Versus Trastuzumab Plus Chemotherapy in HER2-positive Breast CancerStatus unknownNCT03273595Phase 2
- Apatinib Versus Bevacizumab in Second-line Therapy for Colorectal Cancer(ABST-C)Status unknownNCT03271255Phase 2
- A Study of Apatinib Combined With S1 in Patients With Advanced Gastric CancerStatus unknownNCT03271073Phase 2
- Obinutuzumab With or Without Umbralisib, Lenalidomide, or Combination Chemotherapy in Treating Patients With Relapsed or Refractory Grade I-IIIa Follicular LymphomaActive, not recruitingNCT03269669Phase 2
- A Study of Apatinib and Tegafur Gimeracil Oteracil in Locally Advanced Squamous Cell Carcinoma of the Head and NeckCompletedNCT03267121Phase 2
- A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Clinical Activity of GSK525762 Plus Trametinib in Subjects With Solid TumorsWithdrawnNCT03266159Phase 2
- Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological MalignanciesCompletedNCT03263637Phase 1
- The Effect of BMS-986195 Combined With an Oral Contraceptive (Ethinyl Estradiol/Norethindrone) in Healthy Female PatientsCompletedNCT03262740Phase 1
- The Effect of BMS-986165 Combined With an Oral Contraceptive (Ethinyl Estradiol/Norethindrone) in Healthy Female PatientsCompletedNCT03262727Phase 1
- Efficacy and Safety of Apatinib As Third Line Therapy in Patients With Advanced Ovarian CancerStatus unknownNCT03262545Phase 2
- Adjuvant Therapy With Apatinib for HCC Patients With PVTT Who Underwent Radical ResectionStatus unknownNCT03261791Phase 2
- Study to Evaluate the Safety, Preliminary Efficacy and Pharmacokinetics of 3810Status unknownNCT03260179Phase 1
- Study of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AMLCompletedNCT03258931Phase 3
- IMRT and Timing in Combination With EGFRTKI for Stage IV Non-small-cell Lung CancerStatus unknownNCT03258671Not applicable
- A Study to Investigate the Effect of Single Dose of AZD6094 (600 mg) on Cardiac Repolarization in Healthy VolunteersCompletedNCT03258515Phase 1
- A Study to Evaluate eFT508 Alone and in Combination With Avelumab in Subjects With MSS Colorectal CancerCompletedNCT03258398Phase 2
- A Pharmacokinetic Study of Ruxolitinib Phosphate Cream in Pediatric Subjects With Atopic DermatitisCompletedNCT03257644Phase 1
- Study of AZD9291 in NSCLC Patients Harboring T790M Mutation Who Failed EGFR TKI and With Brain and/or LMSStatus unknownNCT03257124Phase 2
- Twice-daily Tacrolimus and Everolimus Convert to Once-daily Tacrolimus and Everolimus in Liver Transplant RecipientCompletedNCT03256864Phase 4
- Compare Apatinib Plus Chemotherapy Drug Versus Chemotherapy Drug as Second-line Treatment in NSCLCTerminatedNCT03256721Phase 2
- Clinical Study on Treatment of Apatinib Mesylate in First-line Maintenance of Advanced Gastric CancerStatus unknownNCT03255811Not applicable
- Study of SHR0302 Tablets (SHR0302) as Monotherapy in Active Rheumatoid Arthritis (RA) PatientsCompletedNCT03254966Phase 2
- A Study to Evaluate BMS-986165 Tablet Formulation Relative to BMS-986165 Capsule Formulation and the Effect of a High-Fat/ High-Calorie Meal and Increased Gastric pH on the BMS-986165 Tablet FormulationCompletedNCT03254784Phase 1
- Vinorelbine Plus Apatinib Versus Vinorelbine in Advanced Triple-Negative Breast CancerCompletedNCT03254654Phase 2
- A Study of Second-line Treatment With Apatinib in Patients With Advanced Intrahepatic CholangiocarcinomaCompletedNCT03251443Phase 2
- Apatinib and Irinotecan Combination Treatment in Unresectable or Metastatic Esophageal Squamous Cell CarcinomaTerminatedNCT03251417Phase 2
- Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AMLCompletedNCT03250338Phase 3
- Absorption, Metabolism, Excretion and Absolute BioavailabilityCompletedNCT03250039Phase 1
- A Depot Formulation of Sunitinib Malate (GB-102) in Subjects With Neovascular (Wet) Age-related Macular DegenerationCompletedNCT03249740Phase 1
- Neadjuvant Multi-agent Chemotherapy or Letrozole Plus Ribociclib in Luminal B/HER2-negative Breast Cancer.CompletedNCT03248427Phase 2
- Sorafenib, Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell TransplantActive, not recruitingNCT03247088Phase 1/2
- A Study of DBPR112 in Patients With Head and Neck Cancer and EGFR Mutated Lung CancerTerminatedNCT03246854Phase 1
- A Study of BMS-986195 in Healthy Male SubjectsCompletedNCT03245515Phase 1
- A Study To Test The Effect Of Apatinib On P450 EnzymesStatus unknownNCT03245307Phase 1
- Study of Chiauranib in Patients With Advanced Hepatocellular CarcinomaCompletedNCT03245190Phase 1/2
- Efficacy of MEK (Trametinib) and BRAFV600E (Dabrafenib) Inhibitors With Radioactive Iodine (RAI) for the Treatment of Refractory Metastatic Differentiated Thyroid CancerCompletedNCT03244956Phase 2
- Phase I Study of the Combination of Apatinib and POFStatus unknownNCT03244774Phase 1
- Food Effect, Oral & Intravenous Pharmacokinetics and Absolute Bioavailability of BAY1834845 Including Drug-drug Interaction With MethotrexateCompletedNCT03244462Phase 1
- Low-dose Apatinib Combined With Neoadjuvant Chemotherapy in the Treatment of Early Triple Negative Breast CancerCompletedNCT03243838Phase 2
- Tolerability, Safety, Pharmacokinetics and Efficacy of HS-10241 Single Agent or Combined With Apatinib in Patients With Advanced Solid TumorsStatus unknownNCT03243643Phase 1
- An Initial Safety Study of Gedatolisib Plus PTK7-ADC for Metastatic Triple-negative Breast CancerCompletedNCT03243331Phase 1
- The Efficacy and Safety of Induction-Maintenance Protocol for Patients With Chronic Myelogenous LeukaemiaStatus unknownNCT03241199Phase 2
- Impact of Changing the Dosing Regimen on the PK Profile of ODM-203CompletedNCT03240445Phase 1
- Study of Oral cMET Inhibitor INC280 in Chinese Patients With EGFR Wild-type Advanced Non-small Cell Lung Cancer (NSCLC)WithdrawnNCT03240393Phase 2
- Efficacy and Safety of Precision Therapy in Refractory TumorStatus unknownNCT03239015Phase 2
- Ribociclib and Gemcitabine Hydrochloride in Treating Patients With Advanced or Metastatic Solid TumorsCompletedNCT03237390Phase 1
- Safety and Pharmacokinetic Study of PF-06700841 in Japanese Healthy VolunteersCompletedNCT03236493Phase 1
- A Safety and Tolerability Study of Pemigatinib in Japanese Subjects With Advanced Malignancies - (FIGHT-102)CompletedNCT03235570Phase 1
- Safety and Pharmacokinetic Study of PF-06651600 in Japanese Healthy VolunteersCompletedNCT03232905Phase 1
- Ibrutinib Plus Rituximab and Lenalidomide in Treating Elderly Participants With Newly Diagnosed Mantle Cell LymphomaWithdrawnNCT03232307Phase 2
- HMPL-813 in Treating Patients With GlioblastomaStatus unknownNCT03231501Phase 1
- Varlitinib Plus Capecitabine in Chinese Patients With Advanced or Metastatic Biliary Tract CancerCompletedNCT03231176Phase 2
- Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.Active, not recruitingNCT03229200Phase 4
- Apatinib Plus XELOX as Neoadjuvant Therapy in Locally Advanced Gastric CancerStatus unknownNCT03229096Phase 2
- Nilotinib Versus Imatinib in Treatment of Patients With Newly Diagnosed Chronic Myeloid LeukemiaStatus unknownNCT03228303Early Phase 1
- Olmutinib Trial in T790M (+) NSCLC Patients Detected by Liquid Biopsy Using BALF Extracellular Vesicular DNACompletedNCT03228277Phase 2
- Apatinib for Resectable Colorectal CancerWithdrawnNCT03228043Not applicable
- Evaluation of Trastuzumab in Combination With Lapatinib or Pertuzumab in Combination With Trastuzumab-Emtansine to Treat Patients With HER2-positive Metastatic Colorectal CancerStatus unknownNCT03225937Phase 2
- Study of Entospletinib (ENTO) in Newly Diagnosed DLBCL Patients With aaIPI>=1 Treated by ChemiotherapyTerminatedNCT03225924Phase 1/2
- Trametinib and Pembrolizumab in Treating Patients With Recurrent Non-small Cell Lung Cancer That Is Metastatic, Unresectable, or Locally AdvancedActive, not recruitingNCT03225664Phase 1/2
- Apatinib Combined With Chemotherapy for Esophageal Squamous Cell Cancer After the Failure of Standard TreatmentStatus unknownNCT03224221Phase 2
- Vemurafenib Plus Cobimetinib in Advanced or Metastatic Melanoma PatientsTerminatedNCT03224208Phase 2
- A Phase III Study of Fruquintinib in Combination With Paclitaxel in Second Line Gastric Cancer(FRUTIGA)CompletedNCT03223376Phase 3
- Study of Icotinib Hydrochloride Cream in Patients With Mild to Moderate PsoriasisTerminatedNCT03222622Phase 2
- A Study to Evaluate the Effect of a Potent Cytochrome P450 (CYP) 3A Inhibitor on IpatasertibCompletedNCT03222310Phase 1
- Abemaciclib (LY2835219) in Patients With Recurrent Primary Brain TumorsActive, not recruitingNCT03220646Phase 2
- Proton Pump Inhibitor (PPI, Rabeprazole) Effect On Tablet Formulation Of PalbociclibCompletedNCT03220191Phase 1
- Impact of eHealth-support on Quality of Life in Metastatic Breast Cancer Patients Treated With Palbociclib and Endocrine TherapyTerminatedNCT03220178Phase 4
- A Phase II Study of Palbociclib for Recurrent or Refractory Advanced Thymic Epithelial TumorStatus unknownNCT03219554Phase 2
- Patient-Derived Xenografts in Personalizing Treatment for Patients With Relapsed/Refractory Mantle Cell LymphomaCompletedNCT03219047Early Phase 1
- Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD2811 Nanoparticles as Monotherapy or in Combination in Acute Myeloid Leukemia Participants.TerminatedNCT03217838Phase 1
- Epacadostat (INCB24360) in Combination With Sirolimus in Advanced MalignancyActive, not recruitingNCT03217669Phase 1
- Multicenter Randomized Two-arms Study Evaluating the BK Viral Clearance in Kidney Transplant Recipients With BK Viremia.CompletedNCT03216967Phase 4
- Phase Ib/II Study of Chiauranib in Patients With Small Cell Lung CancerCompletedNCT03216343Phase 1