Phosphodiesterase 5 Inhibitors: all 685 studies that test it

Page 2 of 7. Open to participants first (38), then studies with results posted, then the rest; newest registration first within each.

• Phase 3 Study of Tadalafil Once-Daily in Asian Men With Benign Prostatic Hyperplasia (BPH)CompletedNCT01460342Phase 3Results posted
• A Trial of Tadalafil and Glycemic TraitsCompletedNCT01444651Phase 3Results posted
• Renin-Angiotensin and Fibrinolysis in Humans: Effect of Long-Term PDE5 Inhibition on Glucose HomeostasisTerminatedNCT01409993Phase 4Results posted
• Study of Sildenafil to Treat Newborns With Persistent Pulmonary HypertensionTerminatedNCT01409031Phase 2Results posted
• Pharmacokinetic Effects of QTI571 on Sildenafil and Bosentan in Pulmonary Arterial Hypertension ParticipantsCompletedNCT01392469Phase 3Results posted
• Administration of Tadalafil in Conjunction With Lenalidomide and Dexamethasone in Patients With Multiple MyelomaTerminatedNCT01374217Phase 2Results posted
• A Study of Tadalafil and Sildenafil in Men With Erectile Dysfunction in ChinaCompletedNCT01352507Phase 4Results posted
• Effect of Sildenafil on the Microcirculatory Blood Flow and Endothelial Progenitor Cells in Systemic SclerosisCompletedNCT01347008Phase 3Results posted
• Study of Sildenafil Citrate on Insulin Resistance in African AmericanCompletedNCT01334554Phase 1/2Results posted
• Tadalafil for Sarcoidosis Associated Pulmonary HypertensionCompletedNCT01324999Phase 2/3Results posted
• Treprostinil Combined With Tadalafil for Pulmonary HypertensionTerminatedNCT01302444Phase 4Results posted
• A Study to Evaluate Sildenafil for the Treatment of Lymphatic MalformationsCompletedNCT01290484Phase 1/2Results posted
• Aortic Stenosis and PhosphodiEsterase Type 5 iNhibition (ASPEN): A Pilot StudyTerminatedNCT01275339Phase 4Results posted
• Aortic Stenosis and PhosphodiEsterase iNhibition With Aortic Valve Replacement (ASPEN-AVR): A Pilot StudyTerminatedNCT01272388Phase 4Results posted
• Pharmacokinetics Of Sildenafil Orally Disintegrating Tablet Formulation Given With Or Without Food.CompletedNCT01254396Phase 1Results posted
• A Pharmacokinetic Drug-Drug Interaction (DDI) Study Between Sitaxsentan And Sildenafil, And Between Sitaxsentan And Tadalafil After Multiple DosesTerminatedNCT01244620Phase 1Results posted
• Study Evaluating The Safety And Efficacy Of PF-03049423 In Subjects With Ischemic StrokeTerminatedNCT01208233Phase 2Results posted
• A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis PatientsCompletedNCT01187901Phase 2Results posted
• A Study of Tadalafil in Benign Prostatic HyperplasiaCompletedNCT01183650Phase 1Results posted
• Evaluation of the Pharmacodynamic Effect of the Combination of Sildenafil and Riociguat on Blood Pressure and Other Safety Parameters.CompletedNCT01179334Phase 2Results posted
• A Study of First-Line Ambrisentan and Tadalafil Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)CompletedNCT01178073Phase 3Results posted
• Sildenafil in Single Ventricle PatientsCompletedNCT01169519Phase 1Results posted
• Revatio for Heart Disease in Duchenne Muscular Dystrophy and Becker Muscular DystrophyTerminatedNCT01168908Phase 2Results posted
• A Study of LY900010 in Erectile DysfunctionCompletedNCT01160289Phase 2Results posted
• A Study in Benign Prostatic HyperplasiaCompletedNCT01152190Phase 3Results posted
• A Study of Tadalafil Use With Finasteride in Men With Enlarged Prostates and Urinary SymptomsCompletedNCT01139762Phase 3Results posted
• Effects of Sildenafil on CFTR-dependent Ion Transport ActivityCompletedNCT01132482Phase 2Results posted
• A Study in Erectile DysfunctionCompletedNCT01130532Phase 4Results posted
• A Study in Patients With Erectile DysfunctionCompletedNCT01122264Phase 4Results posted
• Acute Hemodynamic Effects of Sildenafil in Patients With Severe Aortic StenosisCompletedNCT01060020Phase 4Results posted
• Role of Skeletal Muscle Nitric Oxide Production in Age-related Fatigue and FatigabilityCompletedNCT01059994Not applicableResults posted
• A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic SclerosisCompletedNCT01042158Phase 4Results posted
• Treatment of Erectile Dysfunction ICompletedNCT01037244Phase 3Results posted
• Treatment of Erectile Dysfunction IICompletedNCT01037218Phase 3Results posted
• A Study of Tadalafil After Radical ProstatectomyCompletedNCT01026818Phase 4Results posted
• Targeting Vascular Reactivity in Idiopathic Pulmonary FibrosisTerminatedNCT00981747Phase 2/3Results posted
• A Study of Tadalafil in Men With Benign Prostatic HyperplasiaCompletedNCT00970632Phase 3Results posted
• The Effects of Sildenafil on Exercise Function and Capacity in Patients With Fontan CirculationCompletedNCT00964782Phase 4Results posted
• Sildenafil for Treatment of Priapism in Men With Sickle Cell AnemiaCompletedNCT00940901Phase 2Results posted
• Tadalafil in Preventing Erectile Dysfunction in Patients With Prostate Cancer Treated With Radiation TherapyCompletedNCT00931528Phase 3Results posted
• A Relative Bioavailability Study Between Two Formulations Of Sildenafil CitrateCompletedNCT00904748Phase 1Results posted
• Research Evaluating an Investigational Medication for Erectile Dysfunction - Post-ProstatectomyCompletedNCT00895011Phase 3Results posted
• A Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive TractCompletedNCT00894413Phase 2Results posted
• Sildenafil to Improve Exercise Capacity in People With Thalassemia and Pulmonary HypertensionCompletedNCT00872170Phase 2/3Results posted
• Multinational Study to Evaluate Tadalafil in Asian Men With Signs and Symptoms of Benign Prostatic HyperplasiaCompletedNCT00861757Phase 3Results posted
• A Study in the Treatment of Erectile Dysfunction and Benign Prostate HyperplasiaCompletedNCT00855582Phase 3Results posted
• Study To Investigate The Hemodynamic Effects Of Single Dose Vardenafil In Subjects Receiving MaravirocCompletedNCT00853840Phase 4Results posted
• Long-Term Safety and Efficacy Study of Avanafil in Men With Erectile DysfunctionCompletedNCT00853606Phase 3Results posted
• A Study of Tadalafil in Men With Benign Prostatic Hyperplasia Symptoms Who Are Being Treated With Alpha BlockersCompletedNCT00848081Phase 3Results posted
• Tadalafil in Treating Patients Undergoing Surgery for Cancer of the Oral Cavity or OropharynxCompletedNCT00843635Not applicableResults posted
• Sulindac in Preventing Melanoma in Healthy Participants Who Are at Increased Risk of MelanomaCompletedNCT00841204Phase 2Results posted
• Effect of Tadalafil Once a Day in Men With Erectile DysfunctionCompletedNCT00836693Phase 3Results posted
• A Study in Erectile DysfunctionCompletedNCT00833638Phase 4Results posted
• Study to Treat Patients Who Have Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) With Tadalafil DailyCompletedNCT00827242Phase 3Results posted
• Tadalafil for the Treatment of Raynaud'sCompletedNCT00822354Not applicableResults posted
• Research Evaluating an Investigational Medication for Erectile Dysfunction - Diabetic ED (REVIVE-D)CompletedNCT00809471Phase 3Results posted
• Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding SildenafilTerminatedNCT00796666Phase 3Results posted
• Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjects With Pulmonary Arterial Hypertension (PAH) To Assess Long-Term SafetyTerminatedNCT00796510Phase 3Results posted
• Research Evaluating an Investigational Medication for Erectile Dysfunction - General EDCompletedNCT00790751Phase 3Results posted
• Study of Tadalafil Once-a-Day for 12 Weeks in Japanese Men With Benign Prostatic Hyperplasia Followed by an Open-Label ExtensionCompletedNCT00783094Phase 2Results posted
• Effects of Viagra on Heart Function in Patients With Heart FailureCompletedNCT00781508Phase 4Results posted
• Evaluating the Effectiveness of Sildenafil at Improving Health Outcomes and Exercise Ability in People With Diastolic Heart Failure (The RELAX Study)CompletedNCT00763867Phase 3Results posted
• Renin Angiotensin Aldosterone System (RAAS) and Fibrinolysis in Humans: ACEi and PE5iCompletedNCT00750308Not applicableResults posted
• Study of Vardenafil in Patients Suffering From Erectile Dysfunction and Metabolic SyndromeCompletedNCT00738400Phase 4Results posted
• A Study for Patients With Erectile Dysfunction to Test Whether Tadalafil Taken Once a Day Can Better Improve Psychological Outcomes.CompletedNCT00734604Phase 3Results posted
• Cardiovascular Effects of Chronic Sildenafil in Men With Type 2 DiabetesCompletedNCT00692237Phase 4Results posted
• Renin-Angiotensin Aldosterone System and Fibrinolysis Interaction in Humans-Specific Aim 3CompletedNCT00685945Not applicableResults posted
• Safety and Efficacy of Sildenafil in Cystic Fibrosis (CF) Lung DiseaseCompletedNCT00659529Phase 1/2Results posted
• Use of Sildenafil (Viagra) to Alter Fatigue, Functional Status and Impaired Cerebral Blood Flow in Patients With CFSCompletedNCT00598585Phase 4Results posted
• Study the Safety and Effectiveness of Tadalafil on High Blood Pressure in the Blood Vessel Going From the Heart to the LungsCompletedNCT00549302Phase 3Results posted
• Pilot Study Investigating Safety and Efficacy of Tadalafil as Treatment for Benign Prostatic Hyperplasia (BPH) in Asian MenCompletedNCT00540124Phase 2Results posted
• Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary FibrosisCompletedNCT00517933Phase 3Results posted
• Sildenafil After the Fontan OperationCompletedNCT00507819Phase 2Results posted
• Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell DiseaseTerminatedNCT00492531Phase 2Results posted
• A Study To Assess If 10 mg Vardenafil (BAY38-9456) Taken Twice Daily For 6 Weeks Has An Effect On Bladder FunctionCompletedNCT00478881Phase 2Results posted
• Pharmacologic Treatment of Congenital Nephrogenic Diabetes InsipidusCompletedNCT00478335Not applicableResults posted
• A Multicenter, Open Label, To Evaluate The Efficacy And Satisfaction Of Patrex® In Men With Erectile Dysfunction.CompletedNCT00468650Phase 4Results posted
• Vardenafil in Greenlight(TM) Laser Surgery of Benign Prostate HypertrophyCompletedNCT00461123Phase 2Results posted
• Open Label Study of Sildenafil in Patients With Pulmonary Arterial HypertensionCompletedNCT00454207Phase 3Results posted
• To Assess The Efficacy and Safety Of Oral Sildenafil in the Treatment of Pulmonary Arterial Hypertension.TerminatedNCT00430716Phase 4Results posted
• Tadalafil Taken Daily Compared to Placebo on Improvement of Getting and Maintaining an Erection and Sexual Quality of LifeCompletedNCT00422734Phase 3Results posted
• Bevacizumab/Tarceva and Tarceva/Sulindac in Squamous Cell Carcinoma of the Head and NeckTerminatedNCT00392665Phase 2Results posted
• Effects of Tadalafil Once a Day for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic HyperplasiaCompletedNCT00386009Phase 2Results posted
• Study of Tadalafil Once-a Day for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic HyperplasiaCompletedNCT00384930Phase 2/3Results posted
• Sulindac in Preventing Lung Cancer in Current or Former Smokers With Bronchial DysplasiaCompletedNCT00368927Phase 2Results posted
• Sildenafil Study to Treat Idiopathic Pulmonary FibrosisCompletedNCT00359736Phase 2Results posted
• Atorvastatin Calcium, Oligofructose-Enriched Inulin, or Sulindac in Preventing Cancer in Patients at Increased Risk of Developing Colorectal NeoplasiaCompletedNCT00335504Phase 2Results posted
• Assess the Efficacy and Safety of Sildenafil When Added to Bosentan in the Treatment of Pulmonary Arterial HypertensionCompletedNCT00323297Phase 4Results posted
• The "VISION" Trial: Ventavis Inhalation With Sildenafil to Improve and Optimize Pulmonary Arterial HypertensionTerminatedNCT00302211Phase 3Results posted
• Impact Of Viagra On Sexual Satisfaction Of Men With Mild Erectile Dysfunction Who Are Sexually DissatisfiedCompletedNCT00301262Phase 4Results posted
• A Randomized Study of Sulindac in Oral Premalignant LesionsCompletedNCT00299195Not applicableResults posted
• Exisulind and Intermittent Androgen Suppression (ADT) in Biochemical Relapsed Prostate CancerCompletedNCT00283803Phase 2Results posted
• A Randomized, Double-Blind, Placebo-Controlled Study of Sildenafil in Children With Pulmonary Arterial Hypertension.CompletedNCT00159913Phase 3Results posted
• A Long Term Extension Study Evaluating Safety Of Sildenafil Citrate When Used To Treat Pulmonary Arterial Hypertension (PAH) In ChildrenCompletedNCT00159874Phase 3Results posted
• The Efficacy and Safety of Sildenafil Citrate Used in Combination With Intravenous Epoprostenol in PAHCompletedNCT00159861Phase 3Results posted
• Chronic Sildenafil for Severe Diaphragmatic HerniaTerminatedNCT00133679Phase 4Results posted
• Viagra in the Treatment of Primary DysmenorrheaCompletedNCT00123162Phase 1/2Results posted
• Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon PolypsCompletedNCT00118365Phase 3Results posted
• Sildenafil for Chronic Obstructive Pulmonary DiseaseCompletedNCT00104637Phase 2Results posted
• Sulindac and Tamoxifen in Treating Patients With Desmoid TumorCompletedNCT00068419Phase 2Results posted

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