Drug
Naldemedine clinical trials
Also written Symproic® and S-297995.
Keep track of what changes. Save the naldemedine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
10 studies that test it; most in 2013 (3)
| Year | Studies |
|---|---|
| 2010 | 1 |
| 2011 | 1 |
| 2013 | 3 |
| 2020 | 1 |
| 2022 | 1 |
| 2023 | 1 |
| 2024 | 1 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 7 · Other 3
Shionogi (7) · Asbjørn Mohr Drewes (2) · International University of Health and Welfare (1)
Studies
Open first, then newest update. How each study uses naldemedine is read from its arms, and is right about nine times in ten.
Testing it · 10
- Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving OpioidsRecruitingPhase 1/2ShionogiNCT05588323Written as Naldemedine
- The Effect of Naldemedine on Opioid-induced Bowel DysfunctionRecruitingPhase 2Asbjørn Mohr DrewesNCT06334198Written as Naldemedine
- Prophylactic Use of Naldemedine on Opioid-induced Nausea and Vomiting in Patients With Cancer: POSEIDON StudyCompletedPhase 4International University of Health and WelfareNCT07038551Written as Naldemedine
- Effects of a Peripherally Acting µ-opioid Receptor Antagonist on Recurrent Acute PancreatitisActive, not recruitingPhase 2/3Asbjørn Mohr DrewesNCT04966559Written as Naldemedine 0.2 MG Oral Tablet
- A Study of Naldemedine in Participants Undergoing Surgeries That Include a Bowel Resection or Bowel TransectionTerminatedPhase 2ShionogiNCT04355169Written as Naldemedine
- Long Term Safety of NaldemedineCompletedPhase 3ShionogiNCT01965652Written as Naldemedine
- A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignant Chronic Pain Receiving Opioid TherapyCompletedPhase 2ShionogiNCT01443403Written as Naldemedine
- Study to Evaluate the Safety and Efficacy of Naldemedine (S-297995) for the Treatment of Opioid-Induced Bowel Dysfunction in Subjects With Chronic PainCompletedPhase 2ShionogiNCT01122030Written as Naldemedine
- Efficacy and Safety of Naldemedine in Treating Opioid-induced ConstipationCompletedPhase 3ShionogiNCT01993940Written as Naldemedine
- Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced ConstipationCompletedPhase 3ShionogiNCT01965158Written as Naldemedine
Codes
What other systems call naldemedine · ClinicalTrials.gg INT000715
- MeSH (NLM) C000620491naldemedineConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 03KSI6WLXHNALDEMEDINEConfirmed FDA, NLM, Wikidata
- RxNorm 1876597Confirmed FDA, Wikidata
- Wikidata Q6960846naldemedineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C175156NaldemedineOne source FDA
- DrugBank DB11691One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000620491 | naldemedine | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 03KSI6WLXH | NALDEMEDINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1876597 | — | Confirmed FDA, Wikidata |
| Wikidata | Q6960846 | naldemedine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C175156 | Naldemedine | One source FDA |
| DrugBank | DB11691 | — | One source Wikidata |
Also registered as naldemedine tosylate (UNII V1N8F1RVVO · RxNorm 1876598).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.