N-Methyl-3,4-methylenedioxyamphetamine: all 89 studies that test it

Page 1 of 1. Open to participants first (22), then studies with results posted, then the rest; newest registration first within each.

• MDMA Therapy in Veterans With PTSDRecruitingNCT07569159Phase 2
• Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy ParticipantsRecruitingNCT07494214Phase 1
• A Phase 2A Trial of DT402 for Autism Spectrum DisorderRecruitingNCT07303907Phase 2
• Ecstasy to Alleviate SEvere Chronic Neuropathic Pain TrialRecruitingNCT07301632Phase 2
• MDMA-Assisted Massed Exposure Therapy for PTSDRecruitingNCT07288151Phase 2
• Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)RecruitingNCT06989957Phase 1
• Plasma Oxytocin Changes in Response to Low-dose MDMA vs. Placebo in Patients With Arginine Vasopressin Deficiency and Healthy ControlsRecruitingNCT06789705Not applicable
• Investigation of Psychedelic Effects in Psychoactive SubstancesRecruitingNCT06772753Phase 1
• MDMA in Borderline Personality DisorderRecruitingNCT06683014Phase 2
• Dose Optimization of MDMA-Assisted Therapy for PTSDRecruitingNCT06418178Phase 2
• MDMA-assisted Therapy for FibromyalgiaRecruitingNCT06066853Early Phase 1
• MDMA-assisted Cognitive Processing Therapy Versus Cognitive Processing Therapy for Veterans With Severe Posttraumatic Stress DisorderRecruitingNCT05837845Phase 2
• MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress DisorderRecruitingNCT05790239Phase 2
• MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)RecruitingNCT05783817Phase 2
• Tolerability of MDMA in SchizophreniaRecruitingNCT05770375Phase 1/2
• MDMA Plus Exposure Therapy for PTSDEnrolling by invitationNCT05746572Phase 2
• Preliminary Effectiveness of Hybrid Individual and Group MDMA-assisted Therapy for War-related PTSDRecruitingNCT05732155Phase 2
• MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress DisorderRecruitingNCT05709353Phase 2
• MDMA-assisted Therapy for Adjustment Disorder (AD) in Dyads of Patients With Cancer and a Concerned Significant OtherRecruitingNCT05584826Phase 2
• The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy TrainingEnrolling by invitationNCT05570708Not applicable
• MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers and First RespondersNot yet recruitingNCT05455996Phase 2
• MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic FunctionNot yet recruitingNCT03606538Phase 1
• Study Comparing Two Versus Three Active MDMA-assisted Sessions in U.S. Military Veterans With Chronic PTSDTerminatedNCT04784143Phase 2Results posted
• A Multi-Site Open-Label Extension Study of MDMA-Assisted Psychotherapy for PTSDCompletedNCT04714359Phase 3Results posted
• A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2)CompletedNCT04077437Phase 3Results posted
• Effects of Drugs on Responses to Brain and Emotional ProcessesCompletedNCT04053036Early Phase 1Results posted
• Open Label Study of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-StudyCompletedNCT04030169Phase 2Results posted
• Effect of Stimulant Drugs on Social PerceptionCompletedNCT03790618Phase 1Results posted
• A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)CompletedNCT03537014Phase 3Results posted
• Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD (Canada)CompletedNCT03485287Phase 2Results posted
• Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSDCompletedNCT03282123Phase 2Results posted
• Effects of MDMA on Emotional and Social MemoriesCompletedNCT03050541Not applicableResults posted
• MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSDCompletedNCT02876172Phase 1/2Results posted
• MDMA-Assisted Psychotherapy for Anxiety Associated With a Life-Threatening IllnessCompletedNCT02427568Phase 2Results posted
• Phase 2 Pilot Safety Study of MDMA-assisted Therapy for Social Anxiety in Autistic AdultsCompletedNCT02008396Phase 2Results posted
• Randomized, Double-blind, Controlled of MDMA-assisted Psychotherapy in 12 Subjects With PTSDTerminatedNCT01958593Phase 2Results posted
• Effects of MDMA on Social and Emotional ProcessingCompletedNCT01849419Not applicableResults posted
• Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSDCompletedNCT01793610Phase 2Results posted
• Randomized, Double-blind, Placebo-Controlled Pilot Study of MDMA-assisted Therapy for PTSDCompletedNCT01689740Phase 2Results posted
• Additional MDMA-assisted Therapy for People Who Relapsed After MDMA-assisted Therapy TrialCompletedNCT01458327Phase 2Results posted
• Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress DisorderCompletedNCT01211405Phase 2Results posted
• Randomized Placebo-controlled Study of MDMA-assisted Therapy in People With PTSD - IsraelTerminatedNCT00402298Phase 2Results posted
• Study of 3,4-Methylenedioxymethamphetamine-assisted Psychotherapy in People With Posttraumatic Stress DisorderCompletedNCT00353938Phase 2Results posted
• MDMA-Assisted Psychotherapy in People With Posttraumatic Stress DisorderCompletedNCT00090064Phase 2Results posted
• Study of Midomafetamine in Healthy AdultsActive, not recruitingNCT07584720Phase 1
• Acute Effects of MDMA Co-administration on the Response to Psilocybin in Healthy SubjectsCompletedNCT06884514Phase 1
• MDMA-Assisted Therapy for Pathological NarcissismActive, not recruitingNCT06565494Early Phase 1
• MDMA-Assisted Psychotherapy for Treatment Resistant PTSD in AdolescentsWithdrawnNCT06353282Phase 2
• Epigenetics and MDMA-Assisted Psychotherapy for PTSDCompletedNCT06189027Phase 3
• MDMA-assisted Massed Prolonged Exposure for PTSDActive, not recruitingNCT06117306Phase 3
• Does Serotonin System Stimulation Increase Pro-social Behavior? - A Comparative Pharmacological Neuroscientific Study in Healthy HumansCompletedNCT06081179Phase 1
• MDMA-assisted Brief Cognitive Behavioral Conjoint Therapy for PTSDCompletedNCT05979844Phase 3
• Group MDMA-therapy for Veterans With PTSDCompletedNCT05961527Phase 1/2
• Prosocial Effects of MDMACompletedNCT05948683Early Phase 1
• MDMA for AUD/PTSD ComorbidityCompletedNCT05943665Phase 2
• Acute Effects of 3,4-methylenedioxymethamphetamine (MDMA) With and Without a Booster DoseCompletedNCT05809271Phase 1
• Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social FunctionCompletedNCT05379959Early Phase 1
• Acute Effects of R- and S-MDMA in Healthy SubjectsCompletedNCT05277636Phase 1
• Study of Feasibility and Safety of MDMA-Assisted Group Therapy for the Treatment of PTSD in VeteransWithdrawnNCT05173831Phase 2
• Food Effects on Bioavailability of MDMA in Healthy VolunteersCompletedNCT05147402Phase 1
• Social Anxiety MDMA-Assisted Therapy InvestigationCompletedNCT05138068Phase 2
• Drug Effects on Interpersonal InteractionCompletedNCT05123716Early Phase 1
• A Phase 2 Open-Label Treatment Development Study of MDMA-Assisted Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder (PTSD)CompletedNCT05067244Phase 2
• Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSDWithdrawnNCT04968938Phase 2
• Effects of MDMA-like Substances in Healthy SubjectsCompletedNCT04847206Phase 1
• Effects of MDMA Co-administration on the Response to LSD in Healthy SubjectsCompletedNCT04516902Phase 1
• A Multi-Site Study of MDMA-Assisted Psychotherapy for Eating DisordersWithdrawnNCT04454684Phase 2
• MDMA-Assisted Psychotherapy in Veterans With Combat-Related, Refractory PTSDCompletedNCT04264026Phase 2
• Bristol Imperial MDMA in Alcoholism StudyStatus unknownNCT04158778Phase 1
• Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2)WithdrawnNCT04073433Phase 1
• The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.WithdrawnNCT03752918Phase 1
• Effect of Methylenedioxymethamphetamine (MDMA) (Serotonin Release) on Fear ExtinctionCompletedNCT03527316Early Phase 1
• Evaluation of MDMA on Startle ResponseCompletedNCT03181763Phase 1
• Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion ProcessingCompletedNCT03019822Early Phase 1
• Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI StudyCompletedNCT01951508Early Phase 1
• Influence of Bupropion on the Effects of MDMACompletedNCT01771874Phase 1
• U of A/ U of M Beans and Peas Health Claim ProjectCompletedNCT01661543Not applicable
• Effects of MDMA and Methylphenidate on Social CognitionCompletedNCT01616407Early Phase 1
• Emotional Effects of Methylphenidate and MDMA in Healthy SubjectsCompletedNCT01465685Phase 1
• -Methylenedioxymethamphetamine (MDMA, Ecstasy) Induced Changes in Drug Metabolism: Gender and Genetic PolymorphismsCompletedNCT01447472Phase 1
• Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy VolunteersCompletedNCT01404754Phase 1
• Pharmacological Interaction Between Doxazosin and Methylenedioxymethamphetamine (MDMA)CompletedNCT01386177Phase 1
• Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA)CompletedNCT01270672Not applicable
• Neurobiology and Pharmacokinets of Acute MDMA AdministrationCompletedNCT01148342Phase 1
• Pharmacological Interaction Between Clonidine and Methylenedioxymethamphetamine (MDMA)CompletedNCT01136278Phase 1
• Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy)CompletedNCT00990067Phase 1
• Pharmacological Interaction Between Pindolol and MDMA (3,4-Methylenedioxymethamphetamine)CompletedNCT00895804Phase 1
• Interaction Between Reboxetine and 3,4-Methylenedioxymethamphetamine: Pharmacodynamics (PD) and Pharmacokinetics (PK)CompletedNCT00886886Phase 1
• Role of Serotonin in Acute and Subacute MDMA EffectsCompletedNCT00838305Not applicable

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