mTOR inhibitors: all 1,276 studies that test it
Page 9 of 13. Open to participants first (126), then studies with results posted, then the rest; newest registration first within each.
- Tuberous Sclerosis Complex: Facial Angiofibroma Skin CreamCompletedNCT01853423Phase 1
- Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable MelanomaWithdrawnNCT01851408Phase 2
- Therapeutic Efficacy of Topical Sirolimus in Early Stage Cutaneous T-cell Lymphoma (CTCL)WithdrawnNCT01843998Phase 2
- RAD001 in Advanced SarcomaCompletedNCT01830153Phase 2
- Neoadjuvant Rapamycin in Patients Undergoing Radical CystectomyCompletedNCT01827618Early Phase 1
- Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT01822015Early Phase 1
- Sirolimus for Eosinophil-Associated Gastrointestinal DisordersTerminatedNCT01814059Phase 1
- Efficacy and Safety of the Mammalian Target of Rapamycin (mTor Rapamycin) Inhibitor in Vascular MalformationsCompletedNCT01811667Phase 3
- A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Sirolimus in Healthy SubjectsCompletedNCT01809860Phase 1
- Myfortic in High MELD Liver TransplantationWithdrawnNCT01807767Not applicable
- Safety Study of Adding Everolimus to Adjuvant Hormone Therapy in Women With High Risk of Relapse, ER+ and HER2- Primary Breast Cancer, Free of Disease After Receiving at Least One Year of Adjuvant Hormone TherapyActive, not recruitingNCT01805271Phase 3
- Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable OsteosarcomaCompletedNCT01804374Phase 2
- The Efficacy of RAD 001 as Second Line Therapy in Patients With Transitional Cell Carcinoma TCC of the UrotheliumCompletedNCT01801137Phase 2
- Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive ProtocolTerminatedNCT01797315Phase 4
- Sirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed By SurgeryCompletedNCT01791088Phase 1
- Efficacy Study of Sunitinib and Everolimus (Rotational vs Sequential Arm) in Pats. With m Clear Cell Renal CancerTerminatedNCT01784978Phase 2
- Phase 1b/2 Trial Using Lapatinib, Everolimus and Capecitabine for Treatment of HER-2 Positive Breast Cancer With CNS MetastasisCompletedNCT01783756Phase 1/2
- Pharmacokinetic of Everolimus and Atorvastatin Co-administrationCompletedNCT01780948Not applicable
- Everolimus Beyond Progress for Patients Who Had Progress Under Everolimus and ExemestaneTerminatedNCT01773460Phase 3
- Sequential Therapy in Metastatic Renal Cell CarinomaCompletedNCT01731158Phase 2
- Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis ComplexStatus unknownNCT01730209Phase 2/3
- Biomarkers Before and After Nephrectomy of Locally Advanced or Metastatic Renal Cell Carcinoma Treated With EverolimusCompletedNCT01715935Phase 2
- Dose Escalation Study Investigating Everolimus and Dovitinib in Metastatic Clear Cell Renal CancerCompletedNCT01714765Phase 1
- The Impact of Everolimus Based Immunosuppression in the Evolution of Hepatitis C Fibrosis After Liver TransplantationCompletedNCT01707849Phase 3
- Safety and Efficacy of the Early Introduction of Everolimus (Certican®) With Low Dose of Cyclosporine in de Novo Kidney Recipients After 1 Month of TransplantationCompletedNCT01706471Phase 4
- Study of Everolimus, Pemetrexed, Carboplatin, and Bevacizumab to Treat Stage IV Lung CancerCompletedNCT01700400Phase 1
- The Biomarker for Immunosuppressive Agents Metabolism in Chinese Renal Transplant RecipientsStatus unknownNCT01699360Phase 4
- Hydroxychloroquine, Cyclophosphamide, Dexamethasone, and Sirolimus in Treating Patients With Relapsed or Refractory Multiple MyelomaCompletedNCT01689987Phase 1
- Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue SarcomaCompletedNCT01684449Phase 1/2
- Sirolimus for Massive Polycystic LiverStatus unknownNCT01680250Phase 2/3
- Intravitreal Injections of Sirolimus in the Treatment of Geographic AtrophyTerminatedNCT01675947Phase 2
- Sirolimus With Cyclophosphamide and Topotecan for Pediatric/Adolescent Relapsed and Refractory Solid TumorsCompletedNCT01670175Phase 1
- Effects of the Use of "de Novo" Everolimus in Renal Tranplant PopulationStatus unknownNCT01663805Phase 4
- Pilot Study Of Sirolimus Plus Multiagent Chemotherapy For Relapsed/Refractory Acute Lymphoblastic Leukemia/LymphomaTerminatedNCT01658007Early Phase 1
- STORM: Temsirolimus, Rituximab and DHAP for Relapsed and Refractory Diffuse Large B-cell LymphomaStatus unknownNCT01653067Phase 2
- Certican (Everolimus) for Recipients of Kidney From HLA-identical Living DonorsCompletedNCT01653041Phase 4
- Exercise and Low-Dose Rapamycin in Older Adults With CAD:Cardiac Rehabilitation And Rapamycin in Elderly (CARE) TrialCompletedNCT01649960Phase 1
- Study of Everolimus Treatment in Newly-diagnosed Patients With Advanced Gastrointestinal Neuroendocrine TumorsTerminatedNCT01648465Phase 2
- Effect of Different Therapeutic Strategies on Regulatory T Cells in Kidney TransplantationCompletedNCT01640743Not applicable
- Cetuximab and Everolimus in Treating Patients With Metastatic or Recurrent Colon Cancer or Head and Neck CancerCompletedNCT01637194Phase 1
- Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies.CompletedNCT01636908Not applicable
- The Vienna RAP Pilot StudyCompletedNCT01632605Not applicable
- Renal Transplantation in the Elderly - nEverOld StudyStatus unknownNCT01631058Phase 4
- 4EVER - Efficacy, Safety, Health Economics, Translational Research of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast CancerCompletedNCT01626222Phase 3
- Rapamune Improves Outcomes of Severe H1N1 PneumoniaCompletedNCT01620307Phase 2
- Effects of Zortress® + Tacrolimus vs. Standard Immunosuppression on Progression of Coronary Artery Calcifications and Bone Disease in de Novo Renal Transplant RecipientsWithdrawnNCT01612299Not applicable
- Study With Temsirolimus Added to Standard Chemotherapy for Patients Over 60 Years With Acute Myeloblastic LeukemiaCompletedNCT01611116Phase 2
- Study of Everolimus in de Novo Renal Transplant RecipientsTerminatedNCT01609673Not applicable
- A Clinical Trial to Assess the Efficacy and Safety of the Conversion to EverolimusStatus unknownNCT01608412Phase 4
- Vemurafenib in Combination With Everolimus or Temsirolimus With Advanced CancerCompletedNCT01596140Phase 1
- Comparison of Efficacy and Safety of Treatment With a Calcineurin Inhibitor (CNI)Versus a CNI-free Treatment in Renal Transplantation (CIME)CompletedNCT01595984Phase 3
- Sirolimus Use in Angioplasty for Vascular Access ExtensionCompletedNCT01595841Phase 2
- A Prospective, Open Label Study of CERtican in KIdney TransplantationCompletedNCT01594268Phase 4
- Study to Evaluate Safety and Immunologic Biomarker of Rapamune in Patients With Stable Renal Transplant RecipientStatus unknownNCT01592253Not applicable
- Evaluate Safety and Tolerability of Pasireotide LAR in Combination With Everolimus in Advanced Metastatic NETsCompletedNCT01590199Phase 1
- Temsirolimus as Second-line Therapy in HCCStatus unknownNCT01567930Phase 2
- Phase II Study of Everolimus Combined With Octreotide LAR to Treat Advanced GI NETCompletedNCT01567488Phase 2
- The Combination of Rad001 and Rituximab In Patients With Non-hodgkin's LymphomasCompletedNCT01567475Phase 1
- A Study to Identify a Biomarker Predictive for Response on Everolimus in Solid Tumors (CPCT-03)CompletedNCT01566279Not applicable
- Effect of the Inhibition of the Mammalian Target of Rapamycin on Metabolism and ExerciseTerminatedNCT01561404Phase 4
- Phase 1 Trial of the Mammalian Target of Rapamycin (mTOR) Inhibitor Everolimus Plus Radiation Therapy (RT) for Salvage Treatment of Biochemical Recurrence in Prostate Cancer Patients Following ProstatectomyCompletedNCT01548807Phase 1
- Sirolimus and Vismodegib in Treating Patients With Solid Tumors or Pancreatic Cancer That is Metastatic or Cannot Be Removed By SurgeryCompletedNCT01537107Phase 1
- Temsirolimus in Combination With Metformin in Patients With Advanced CancersTerminatedNCT01529593Phase 1
- Controlled Level EVERolimus in Acute Coronary SyndromesCompletedNCT01529554Phase 1/2
- Study of Axitinib and Temsirolimus in Solid TumorsCompletedNCT01529138Phase 1
- Single Arm Study of RAD001 as Monotherapy in Treatment in Advanced CholangiocarcinomaStatus unknownNCT01525719Phase 2
- Everolimus With Multiagent Re-Induction Chemotherapy in Pediatric Patients With ALLCompletedNCT01523977Phase 1
- Gastric Cancer RAD001 StudyCompletedNCT01514110Phase 1/2
- Autophagy Inhibition to Augment Mammilian Target of Rapamycin (mTOR) Inhibition: A Phase I/II Trial of RAD001 and Hydroxychloroquine (HCQ) in Patients With Previously Treated Renal Cell CarcinomaCompletedNCT01510119Phase 1/2
- PhaseII,Open-label,Pilot Study Evaluating the Safety+Efficacy of Certican ® in the Prevention of Chronic Graft-versus-host Disease+Late Pulmonary Complications After Allogeneic Hematopoietic Cell Transplantation BloodCompletedNCT01509560Phase 2
- Ph I/II Study of Allogeneic SCT for Clinically Aggressive Sickle Cell Disease (SCD)Active, not recruitingNCT01499888Phase 1/2
- Kidney Allograft Dysfunction Without Reversible CausesWithdrawnNCT01492894Phase 4
- Trial of XELOX Followed by Radiation Combined With Carboplatin and RAD001 for Esophageal CancerCompletedNCT01490749Phase 1
- Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) PatientsCompletedNCT01490476Phase 2
- Sirolimus/Tacrolimus Combination After HLA Matched Related Peripheral Blood Stem Cell TransplantsTerminatedNCT01488253Phase 2
- RAD001 in Advanced Gastric Cancer Who Failed Standard First-line Treatment With pS6 Ser 240/4 ExpressionCompletedNCT01482299Phase 2
- Effect of Switching to Certican® in Viremia of Hepatitis C Virus in Adult Renal Allograft RecipientsCompletedNCT01469884Phase 4
- Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk NeuroblastomaCompletedNCT01467986Phase 2
- Everolimus in Refractory Testicular Germ Cell CancerCompletedNCT01466231Phase 2
- Study of Everolimus and Low-dose Cyclophosphamide in Patients With Metastatic Renal Cell CancerCompletedNCT01462214Phase 1/2
- Double-blind Placebo-controlled Pilot Study of Sirolimus in Idiopathic Pulmonary Fibrosis (IPF)CompletedNCT01462006Not applicable
- Efficacy,Tolerability,Safety of Temsirolimus in Women With Platinum-refractory Ovarian Carcinoma or Advanced Endometrial CarcinomaCompletedNCT01460979Phase 2
- Study to Evaluate the Safety and Efficacy of Switching Calcineurin Inhibitor to Everolimus After Kidney Transplantation in AdultsStatus unknownNCT01455649Phase 4
- Everolimus in Combination With DHAP in Patients With Relapsed or Refractory Hodgkin LymphomaCompletedNCT01453504Phase 1/2
- Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss PatientsCompletedNCT01430572Phase 1
- Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis RegimensActive, not recruitingNCT01428973Phase 2
- Everolimus in de Novo Liver Transplantation: a Multicentre Randomized StudyStatus unknownNCT01423708Phase 2
- Temsirolimus In Phase 0CompletedNCT01417065Early Phase 1
- Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform NeurofibromasCompletedNCT01412892Phase 2
- A Phase II Study With Tumor Molecular Pharmacodynamic (MPD) Evaluation of Oral mTOR-inhibitor Everolimus (RAD001) 10 mg Daily in Patients Suffering From Classic or Endemic Kaposi's SarcomaTerminatedNCT01412515Phase 2
- Rotating Pazopanib and Everolimus to Avoid ResistanceCompletedNCT01408004Phase 2
- Neo-adjuvant Temsirolimus in Patients With Advanced Renal Cell CarcinomaCompletedNCT01404104Not applicable
- Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin LymphomaCompletedNCT01403415Phase 1
- Efficacy of Certican® in Combination With Myfortic® in RenalStatus unknownNCT01399242Phase 4
- A Phase II Study of Sunitinib or Temsirolimus in Patients With Advanced Rare TumoursActive, not recruitingNCT01396408Phase 2
- Cyclophosphamide and Pulse Dexamethasone With Rapamycin or HydroxychloroquineCompletedNCT01396200Early Phase 1
- Escalating Doses of Torisel in Combination With Three Chemotherapies Regimens: R-CHOP, R-FC or R-DHA for Patients With Relapsed/Refractory Mantle Cell Lymphoma (MCL).CompletedNCT01389427Phase 1/2
- Irinotecan, Cetuximab and Everolimus to Patients With Metastatic Colorectal CancerCompletedNCT01387880Phase 2
- Sirolimus and Gold Sodium Thiomalate in Treating Patients With Advanced Squamous Non-Small Cell Lung CancerWithdrawnNCT01383668Phase 1
- Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryActive, not recruitingNCT01375829Phase 1