mTOR inhibitors: all 1,276 studies that test it
Page 11 of 13. Open to participants first (126), then studies with results posted, then the rest; newest registration first within each.
- Transarterial Chemoembolization With Doxorubicin With or Without Everolimus in Treating Patients With Liver CancerTerminatedNCT01009801Phase 1/2
- Temsirolimus and Sorafenib in Advanced Hepatocellular CarcinomaCompletedNCT01008917Phase 1
- Impact of Conversion From Tacrolimus to Sirolimus in African American Renal Transplant RecipientsStatus unknownNCT00999258Phase 4
- Study of Temsirolimus, Erlotinib and Cisplatin in Solid TumorsCompletedNCT00998036Phase 1
- Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell TransplantationCompletedNCT00993343Phase 3
- A Study of Combination of Temsirolimus (Torisel®) and Pegylated Liposomal Doxorubicin (PLD, Doxil®/Caelyx®) in Advanced or Recurrent Breast, Endometrial and Ovarian CancerStatus unknownNCT00982631Phase 1
- Sorafenib Tosylate and Everolimus in Treating Patients With Advanced Solid Tumors and Metastatic Pancreatic Cancer That Does Not Respond to Gemcitabine HydrochlorideCompletedNCT00981162Phase 1
- Study in Non-Clear Cell Renal Carcinoma (Ncc-RCC) Temsirolimus Versus SunitinibCompletedNCT00979966Phase 2
- Everolimus as First-Line Therapy in Treating Patients With Prostate CancerCompletedNCT00976755Phase 2
- Study of RAD001 in Advanced Cholangiocarcinoma: RADiCholStatus unknownNCT00973713Phase 2
- Pharmacokinetics of Everolimus in Subjects With Hepatic InsufficiencyCompletedNCT00968591Phase 1
- Everolimus Dose Finding Study for Stage IV or Recurrent Cervical CancerWithdrawnNCT00967928Phase 1
- Prevention of Transplant Atherosclerosis With Everolimus and Anti-cytomegalovirus TherapyStatus unknownNCT00966836Phase 3
- Panobinostat and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple MyelomaCompletedNCT00962507Phase 1
- Study of Sirolimus With PEG-Asparaginase in Acute Lymphoblastic Leukemia (ALL)WithdrawnNCT00957320Phase 1
- Everolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable Solid Tumors Refractory to Standard TherapyCompletedNCT00949949Phase 1
- Assessment of Systemically Administered Torisel Delivery to Brain Tumors by Intratumoral MicrodialysisWithdrawnNCT00949026Phase 1
- Everolimus, Bicalutamide, and Leuprolide Acetate in Treating Patients Undergoing Radiation Therapy For High-Risk Locally Advanced Prostate CancerCompletedNCT00943956Phase 1
- Temsirolimus in Recurrent Primary Central Nervous System (CNS) LymphomaStatus unknownNCT00942747Phase 2
- Sorafenib in Combination With RAD001 in Patients With Advanced Neuroendocrine TumorsCompletedNCT00942682Phase 1
- Sirolimus and Cetuximab in Advanced MalignanciesCompletedNCT00940381Phase 1
- RAD001 (Everolimus) + Docetaxel + Cisplatin as Induction Chemotherapy in Patients With Local-Regional Advanced Head and Neck CancerCompletedNCT00935961Phase 1
- SORAVE - Sorafenib and Everolimus in Solid TumorsCompletedNCT00933777Phase 1
- Trial to Evaluate Paclitaxel Plus RAD001 in Urothelial CarcinomaTerminatedNCT00933374Phase 2
- Everolimus (RAD001) and Carboplatin in Pretreated Metastatic Breast CancerStatus unknownNCT00930475Phase 1/2
- Topical Rapamycin for FibrofolliculomasCompletedNCT00928798Phase 3
- Study of the mTOR Inhibitor Temsirolimus (CCI-779) to Treat Ovarian Cancer With CA125 Only RelapseTerminatedNCT00926107Phase 2
- Effectiveness of Conversion to Sirolimus Versus Calcineurin Inhibitor (CNI) Reduction in Renal Transplant Patients With Prostate CancerWithdrawnNCT00922129Phase 2/3
- Hydroxychloroquine and Temsirolimus in Treating Patients With Metastatic Solid Tumors That Have Not Responded to TreatmentCompletedNCT00909831Phase 1
- Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal TransplantationStatus unknownNCT00903188Phase 4
- Tarceva/Rapamycin for Children With Low-grade Gliomas With or Without Neurofibromatosis Type 1 (NF1)CompletedNCT00901849Phase 1
- Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung CancerTerminatedNCT00892801Phase 1
- Nutritional and Contractile Regulation of Muscle GrowthCompletedNCT00891696Phase 1
- Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies.CompletedNCT00890500Phase 1
- Safety Study of Calcineurin-Inhibitor-Free Immunosuppression After Liver TransplantationStatus unknownNCT00890253Phase 2
- Subconjunctival Sirolimus for the Treatment of Autoimmune Active Anterior UveitiCompletedNCT00876434Phase 1
- Rapamycin in Relapsed Acute Lymphoblastic LeukemiaCompletedNCT00874562Phase 1
- Everolimus in Treating Patients With Relapsed or Metastatic Endometrial CancerCompletedNCT00870337Phase 2
- A Study of Decitabine in Combination With Escalating Doses of Rapamycin in Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT00861874Phase 1
- Oral Sirolimus for In-Stent RestenosisCompletedNCT00859183Phase 4
- Radiation Therapy (IMRT) + RAD001 (Everolimus) + Cisplatin for Patients With Head and Neck CancerCompletedNCT00858663Phase 1
- Safety Study of Calcineurin Inhibitor Free GvHD Prophylaxis in Allogeneic Stem Cell TransplantationStatus unknownNCT00856505Phase 1/2
- Everolimus in Treating Women With Breast Cancer That Can Be Removed by SurgeryWithdrawnNCT00855114Phase 2
- Safety and Dosage Study of RAD001 (Everolimus) in Combination With Current Standard of Care to Treat Advanced Solid Tumors.CompletedNCT00849550Phase 1
- Temsirolimus for Relapsed/Refractory Hodgkin's LymphomaTerminatedNCT00838955Phase 2
- RAD001 for Non-clear Cell Renal Cell Carcinoma (RCC)CompletedNCT00830895Phase 2
- Global Study Looking at the Combination of RAD001 and Sorafenib to Treat Patients With Advanced Hepatocellular CarcinomaTerminatedNCT00828594Phase 1
- Certican® (Everolimus) Against Cytomegalovirus Disease in Renal Transplant PatientsStatus unknownNCT00828503Phase 2
- RAD001 in Combination With PKC412 in Patients With Relapsed, Refractory or Poor Prognosis AML or MDSActive, not recruitingNCT00819546Phase 1
- A Dose-Ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injection of Sirolimus in Patients With Dry Eye in the Controlled Adverse Environmental (CAE) ModelCompletedNCT00814944Phase 2
- Pharmacokinetics of Immunosuppressive Drugs in Heart Transplant PatientsCompletedNCT00812786Phase 4
- Calcineurin Free Immunosuppression in Renal Transplant RecipientsCompletedNCT00812123Phase 4
- Study to Compare the Safety and Efficacy of Sirolimus (Rapamune) to Tacrolimus (Advagraf) Associated to Mycophenolate Mofetil (CellCept) Between 12 and 36 Months After Kidney TransplantationTerminatedNCT00811915Phase 3
- Everolimus, Carboplatin, and Etoposide in Treating Patients With Small Cell Lung Cancer or Other Advanced Solid TumorsTerminatedNCT00807755Phase 1
- Pasireotide in Combination With RAD001 in Patients With Advanced Neuroendocrine TumorsCompletedNCT00804336Phase 1
- A Study of Temsirolimus and Bevacizumab in Recurrent Glioblastoma MultiformeCompletedNCT00800917Phase 2
- CERTICOEUR: A Secondary Prevention Study of Skin Cancers in Heart Transplant Patients. Everolimus Versus Calcineurin Inhibitors Multicenter TrialCompletedNCT00799188Phase 3
- Temsirolimus and Radiation for Non-Small Cell Lung CancerCompletedNCT00796796Phase 1
- Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM)CompletedNCT00792766Phase 1/2
- S0718 Pazopanib and Temsirolimus in Treating Patients With Advanced Solid TumorsWithdrawnNCT00788580Phase 1
- A Phase Ib Study of Rad001 and Sutent to Treat Renal Cell CarcinomaCompletedNCT00788060Phase 1
- Rituximab, Cladribine, and Temsirolimus in Treating Patients With Newly Diagnosed Mantle Cell LymphomaCompletedNCT00787969Phase 1
- A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain TumorsCompletedNCT00784914Phase 1
- Sirolimus in Combination With MEC in High Risk Myeloid LeukemiasCompletedNCT00780104Phase 1
- Rapamycin in With High-Dose Etoposide and Cytarabine in Relapsed/Refractory Aggressive Lymphoid MalignanciesTerminatedNCT00776373Phase 1/2
- Antiangiogenic Treatment of Hepatocellular Cancer With Bevacizumab and RAD001CompletedNCT00775073Phase 2
- Study of Temsirolimus, Topotecan, and BortezomibCompletedNCT00770731Phase 1
- Erlotinib and Temsirolimus for Solid TumorsCompletedNCT00770263Phase 1
- Safety of Immunosuppression Minimization in Children and Adolescents After Kidney TransplantationCompletedNCT00768729Phase 1
- Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular DegenerationTerminatedNCT00766337Phase 2
- Doxil, Bevacizumab and Temsirolimus TrialCompletedNCT00761644Phase 1
- A Trial of Everolimus and Bevacizumab in Children With Recurrent Solid TumorsCompletedNCT00756340Phase 1
- RAD001 and Lenalidomide in the Treatment of Subjects With Relapsed and Relapsed/Refractory Multiple MyelomaCompletedNCT00729638Phase 1
- Everolimus in Treating Older Patients With Mantle Cell Lymphoma Previously Treated With First-Line or Second-Line ChemotherapyTerminatedNCT00727207Phase 2
- Efficacy Study of Everolimus on Renal Function in Heart Transplant Recipients With Established Chronic Renal FailureCompletedNCT00716573Phase 4
- A Single Arm, Multicenter, Phase II Trial of RAD001 as Monotherapy in the Palliative Treatment of Patients With TCC After Failure of ChemotherapyCompletedNCT00714025Phase 2
- Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular DegenerationTerminatedNCT00712491Phase 1/2
- Study of Rapamycin Plus Ketoconazole in Advanced CancersCompletedNCT00708591Phase 1
- Rapamycin in Advanced CancersCompletedNCT00707135Phase 1
- Study of the Weekly Oral RAD001 in Combination With Oral Topotecan in Patients With Advanced or Recurrent Endometrial CancersCompletedNCT00703807Phase 1
- Phase I Study of Docetaxel and Temsirolimus in Resistant Solid MalignanciesCompletedNCT00703625Phase 1
- Phase I Study of DOXIL and Temsirolimus in Resistant Solid MalignanciesCompletedNCT00703170Phase 1
- Study to Evaluate Effect of Everolimus in Progression of Graft Vascular Illness on Patients With Heart TransplantStatus unknownNCT00695344Phase 4
- A Study To Compare Sirolimus Versus Tacrolimus In De Novo Simultaneous Pancreas- Kidney Allograft Recipients Receiving An Induction Therapy With Antithymocyte Globulin Plus Mycophenolate Mofetil Plus CorticosteroidsStatus unknownNCT00693446Phase 4
- Temsirolimus and Dexamethasone in Treating Patients With Recurrent or Refractory Multiple MyelomaCompletedNCT00693433Phase 1
- Tacrolimus/Sirolimus Versus Tacrolimus/Mycophenolate Mofetil (MMF) Versus Neoral/Sirolimus in Adult, Primary Kidney TransplantationCompletedNCT00681213Phase 4
- Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast CancerCompletedNCT00680758Phase 1
- Trastuzumab With or Without Everolimus in Treating Women With Breast Cancer That Can Be Removed By SurgeryTerminatedNCT00674414Phase 2
- Everolimus and Bortezomib in Treating Patients With Relapsed or Refractory LymphomaTerminatedNCT00671112Phase 1
- A Study Using Tacrolimus, Sirolimus and Bortezomib as Acute Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Peripheral Blood Stem Cell (PBSC) TransplantationCompletedNCT00670423Phase 1
- Rapamycin Plus Bevacizumab in Advanced CancersCompletedNCT00667485Phase 1
- Metformin and Temsirolimus in Treating Patients With Metastatic or Unresectable Solid Tumor or LymphomaCompletedNCT00659568Phase 1
- Phase II Study of RAD001 in a Neoadjuvant Setting in Men With Intermediate or High Risk Prostate CancerStatus unknownNCT00657982Phase 2
- Dose Ranging Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Diabetic Macular EdemaCompletedNCT00656643Phase 2
- Everolimus and Vatalanib in Treating Patients With Advanced Solid TumorsCompletedNCT00655655Phase 1
- Everolimus (RAD001) in Elderly Patients With Acute Myeloid LeukemiaStatus unknownNCT00636922Phase 1
- Low-dose RAD001(Everolimus) Plus Cisplatin-HDFL Chemotherapy for the First-line Treatment of Advanced Gastric CancerCompletedNCT00632268Phase 2
- A Phase I Dose Escalation Study of RAD001 Administered in Patients With Relapsed or Refractory Non-Hodgkin's LymphomaCompletedNCT00622258Phase 1
- Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy SubjectsCompletedNCT00621101Phase 1
- Combination of Temsirolimus and Bevacizumab in Patient With Metastatic Renal Cell CarcinomaCompletedNCT00619268Phase 2