mTOR inhibitors: all 1,276 studies that test it
Page 12 of 13. Open to participants first (126), then studies with results posted, then the rest; newest registration first within each.
- Everolimus in Treating Patients With Relapsed or Refractory Multiple MyelomaCompletedNCT00618345Phase 2
- Sirolimus, Tacrolimus and Short Course Methotrexate for Prevention of Acute GVHD in Recipients of Mismatched Unrelated Donor Allogeneic Stem Cell TransplantationCompletedNCT00612274Early Phase 1
- Bevacizumab and Temsirolimus in Patients With Advanced MalignancyCompletedNCT00610493Phase 1
- CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal ImpairmentCompletedNCT00604357Phase 3
- Everolimus and Low Dose CNI Compared With MMF and Full CNI Dose in Heart Transplanted Patients: One Year Follow upCompletedNCT00596557Phase 4
- Temsirolimus (CCI-770, Torisel) Combined With Cetuximab in Cetuximab-Refractory Colorectal CancerCompletedNCT00593060Phase 1
- Temsirolimus in Combination With Gemcitabine in Previously Untreated Metastatic Pancreatic CancerTerminatedNCT00593008Phase 1
- BEP Study Phase I (Bevacizumab, Everolimus, Panitumumab)CompletedNCT00586443Phase 1
- Interaction Study of Rapamycin and Sunitinib in Patients With Advanced CancersCompletedNCT00583063Early Phase 1
- Safety Study & Effectiveness of Docetaxel With RAD001 and Bevacizumab in Men With Advanced Prostate CancerCompletedNCT00574769Phase 1/2
- Erlotinib and Everolimus in Treating Patients With Metastatic Breast CancerCompletedNCT00574366Phase 1
- Bevacizumab, Everolimus (RAD001), and Lapatinib as Neoadjuvant Chemotherapy Regimes for Primary Breast CancerCompletedNCT00567554Phase 3
- Treatment of Patients Suffering From a Progressive Pancreas Carcinoma With Everolimus (RAD001) and GemcitabineCompletedNCT00560963Phase 1/2
- Pediatric Kidney Transplant Study of Sirolimus, Mycophenolate Mofetil, and Corticosteroids vs Calcineurin Inhibitor Based ImmunosuppressionCompletedNCT00555373Not applicable
- A Phase I Study of SUNITINIB and Rapamycin in Advanced Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00555256Phase 1
- Sirolimus-Based Immunosuppression Therapy in OLT for Patients With HCC Exceeding Milan CriteriaStatus unknownNCT00554125Phase 3
- Everolimus, Cytarabine, and Daunorubicin in Treating Patients With Relapsed Acute Myeloid LeukemiaStatus unknownNCT00544999Phase 1
- This is a 2-year Follow-up Study to Evaluate the Long-term Effects in Patients Who Completed the Study CRAD001A2307.CompletedNCT00531440Phase 3
- This is a Two-year Follow-up Study to Evaluate the Long-term Safety, Tolerability and Efficacy of 2 Different Doses of EverolimusCompletedNCT00531063Phase 3
- Proleukin and Rapamune in Type 1 DiabetesCompletedNCT00525889Phase 1
- A Phase I Study of CCI-779 (Temsirolimus) in Combination With Topotecan in Patients With Gynecologic MalignanciesCompletedNCT00523432Phase 1
- Phase I/Randomized Phase II Study of Second Line Therapy With Irinotecan + Cetuximab +/- RAD001 for Colorectal CancerCompletedNCT00522665Phase 1/2
- Efficacy and Safety of Everolimus (RAD001) in Patients With Advanced Gastric CancerCompletedNCT00519324Phase 2
- Study Comparing Standard Dose and Reduced Dose Tacrolimus With Sirolimus in Renal Transplant PatientsCompletedNCT00519116Phase 4
- Study Comparing Graft Function in Renal Allograft Recepients Receiving Reduced or Standard Dose CsA With SirolimusCompletedNCT00518375Phase 4
- Study Comparing Standard Dose and Reduced Dose Tacrolimus + Sirolimus + Corticosteroids in Renal Allograft RecipientsCompletedNCT00518271Phase 2
- Everolimus in Treating Patients With Relapsed or Refractory Mantle Cell LymphomaCompletedNCT00516412Phase 2
- Hormone Therapy and Temsirolimus in Treating Patients With Relapsed Prostate CancerTerminatedNCT00512668Phase 1
- Phase 1 Study With Sorafenib and SirolimusCompletedNCT00509613Phase 1
- Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant GliomaCompletedNCT00509431Phase 1
- Study Evaluating the Efficacy and Safety of Cyclosporine Reduction in Kidney Transplant Recipients Receiving SirolimusCompletedNCT00507793Phase 4
- Safe Renal Function In Long Term Heart Transplanted PatientsStatus unknownNCT00505102Phase 4
- Phase I Study of Patupilone and RAD001CompletedNCT00496600Phase 1
- Fibrosis in Renal AllograftsStatus unknownNCT00493194Phase 4
- Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and SafetyCompletedNCT00491517Phase 2
- Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAMStatus unknownNCT00490789Phase 2
- A Phase 1 Study Investigating the Combination of RAD001, Cetuximab and Irinotecan as Second-line Therapy After FOLFOX (or XELOX) Plus Bevacizumab in Patients With Metastatic Colorectal CancerCompletedNCT00478634Phase 1
- Anti-Third Party T Lymphocytes With Nonmyeloablative Stem Cell Transplantation for Indolent Lymphoid MalignanciesTerminatedNCT00473551Phase 1
- Phase I Oral mTOR Inhibitor RAD001 in Combo w/ Capecitabine for Metastatic BreastTerminatedNCT00473005Phase 1
- Study Comparing Sirolimus/Prograf vs Sirolimus/CsA in High-Risk Renal Transplant RecipientsCompletedNCT00470665Phase 3
- B-Lymphocyte Immunotherapy in Islet TransplantationTerminatedNCT00468442Phase 2
- Sirolimus and Bevacizumab in Treating Patients With Liver Cancer That Cannot Be Removed by SurgeryCompletedNCT00467194Phase 1
- Safety of RAD001 in Combination With Cisplatin and Etoposide in Lung Cancer PatientsCompletedNCT00466466Phase 1
- Efficacy of RAD001 in Breast Cancer Patients With Bone MetastasesStatus unknownNCT00466102Phase 2
- Feasibility and Safety of Early Switch to Everolimus From Cyclosporine in de Novo Renal Transplant PatientsCompletedNCT00464399Phase 3
- RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAMCompletedNCT00457964Phase 1/2
- Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAMCompletedNCT00457808Phase 2
- Combination of RAD001 With Carboplatin, Paclitaxel and Bevacizumab in Non-small-cell Lung Cancer (NSCLC) PatientsCompletedNCT00457119Phase 1
- Combination of RAD001 and Erlotinib in Patients With Advanced Non Small Cell Lung Cancer Previously Treated Only With ChemotherapyCompletedNCT00456833Phase 1
- Sirolimus in Treating Patients With HIV-Related Kaposi's SarcomaCompletedNCT00450320Phase 1
- Drug Interaction Study of Sorafenib and Rapamycin in Advanced MalignanciesCompletedNCT00449280Phase 1
- Phase I/II Trial of RAD001 Plus Nexavar in Patients With Kidney CancerCompletedNCT00448149Phase 1/2
- Safety Study of RAD001 to Treat Patients With Metastatic Kidney CancerCompletedNCT00446368Phase 2
- Pharmacokinetics of Everolimus and Enteric-Coated Mycophenolatesodium Before and After Withdrawal of Cyclosporine in Renal Transplant PatientsCompletedNCT00443937Phase 4
- Islet Transplantation in Type 1 DiabetesCompletedNCT00434811Phase 3
- Safety of Everolimus and Pemetrexed in Lung Cancer PatientsCompletedNCT00434174Phase 1
- Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy ParticipantsCompletedNCT00433485Phase 1
- Study Evaluating Sirolimus and Cyclosporine in Kidney Transplant RecipientsCompletedNCT00428064Phase 3
- Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast CancerCompletedNCT00426530Phase 1
- Systemic Treatment With Everolimus for the Prevention of MACE After Bare Metal Stent ImplantationStatus unknownNCT00426049Phase 3
- Cisplatin and Everolimus in Treating Patients With Advanced Solid TumorsCompletedNCT00423865Phase 1
- A Study of RAD001 and Sunitinib in Metastatic Renal Cell CarcinomaCompletedNCT00422344Phase 1
- Shift to Everolimus (RAD) Kidney Sparing StudyTerminatedNCT00420537Phase 4
- A Study Combining Treatment With Temsirolimus and Sunitinib for Subjects With Advanced Renal Cell CarcinomaTerminatedNCT00417677Phase 1/2
- Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum CancerCompletedNCT00409994Phase 1/2
- Temsirolimus, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid TumorsCompletedNCT00408655Phase 1
- A Study of Everolimus in Combination With Imatinib in Metastatic MelanomaTerminatedNCT00402662Phase 2
- Immunosuppressive Therapy With Certican (Everolimus) After Lung TransplantationCompletedNCT00402532Phase 3
- Study of Combination of Sirolimus and Sutent in Patients With Advanced Solid Tumors Non-Curable With Standard TherapyTerminatedNCT00402415Phase 1
- Safety and Tolerability of MS-R001 in Patients With Diabetic Macular Edema Secondary to Diabetic RetinopathyCompletedNCT00401115Phase 1
- Lenalidomide and Temsirolimus in Treating Patients With Previously Treated Multiple MyelomaCompletedNCT00398515Phase 1
- Sirolimus Therapy for Poor Prognosis Immunoglobulin A NephropathyCompletedNCT00396721Phase 2
- Randomized Phase I/II of RAD001 in Advanced Hepatocellular Carcinoma (HCC)Status unknownNCT00390195Phase 1/2
- Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma MultiformeCompletedNCT00387400Phase 1
- Sorafenib and RAD001 Renal Cell CarcinomaCompletedNCT00384969Phase 1
- Rapamycin With Grapefruit Juice for Advanced MalignanciesCompletedNCT00375245Phase 1
- Study to Evaluate Safety and Efficacy of Early Calcineurin Inhibitor Withdrawal in Primary Renal AllograftsCompletedNCT00374647Phase 4
- Everolimus in Combination With Cyclosporine A and Prednisolone for the Treatment of Graft Versus Host DiseaseTerminatedNCT00373815Phase 1
- Sirolimus in Treating Patients With Metastatic or Unresectable Solid TumorsCompletedNCT00368914Phase 1
- Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular CarcinomaCompletedNCT00355862Phase 3
- S0528 Lapatinib and Everolimus in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's LymphomaCompletedNCT00352443Phase 1
- Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable MelanomaCompletedNCT00349206Phase 1
- Sirolimus (Rapamune®) for Autosomal Dominant Polycystic Kidney Disease (ADPKD)CompletedNCT00346918Phase 3
- Phase II Trial of RAD001 in Refractory Colorectal CancerCompletedNCT00337545Phase 2
- A Study of the mTOR Inhibitor Rapamycin (Rapamune, Sirolimus) in Combination With Abraxane in Advanced Solid CancersTerminatedNCT00337376Phase 1
- Pharmacokinetic Study on the Combination of Everolimus-TacrolimusStatus unknownNCT00325325Phase 2
- Sirolimus and Cyclosporine for Treatment-Resistant Aplastic AnemiaStatus unknownNCT00319878Phase 1/2
- Antithymocyte Globulin and Sirolimus in Treating Patients With Relapsed Multiple MyelomaCompletedNCT00317798Phase 1
- Temsirolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00316849Phase 1
- Pilot Study to Investigate a Steroid Free Immunosuppressive Regimen for Renal Transplant RecipientsCompletedNCT00306397Phase 4
- Calcineurin Inhibitor Avoidance With Thymoglobulin and Sirolimus in Kidney TransplantationCompletedNCT00305396Phase 4
- Vatalanib and Everolimus in Treating Patients With Advanced Solid TumorsCompletedNCT00303732Phase 1
- Renal Function Optimization With Mycophenolate Mofetil (MMF) Immunosuppressor Regimes (ALHAMBRA)Status unknownNCT00290069Phase 4
- Anti-Thymocyte Globulin, Cyclosporine, and RAD in Islet TransplantationCompletedNCT00286624Phase 1/2
- Study Evaluating Sirolimus in the Treatment of Kidney TransplantCompletedNCT00282217Phase 4
- Bevacizumab, Everolimus, and Erlotinib in Treating Patients With Advanced Solid TumorsCompletedNCT00276575Phase 1
- The Comparison of Tacrolimus and Sirolimus Immunosuppression Based Drug Regimens in Kidney Transplant RecipientsCompletedNCT00275535Phase 4
- The Comparison of Three Different Immunosuppressant Regimens in Kidney Transplant Recipients.CompletedNCT00275522Phase 4
- Temsirolimus in Treating Patients With Metastatic Solid Tumor or Lymphoma That Cannot Be Removed By Surgery Who Have Different Levels of Liver FunctionCompletedNCT00275093Phase 1
- Study Comparing Two Sirolimus Regimens vs. Tacrolimus and Mycophenolate Mofetil Regimen in Kidney Transplant RecipientsCompletedNCT00266123Phase 4