Metformin: all 1,377 studies that test it

Page 9 of 14. Open to participants first (169), then studies with results posted, then the rest; newest registration first within each.

• Study of Metformin Plus Oligomeric Procyanidin Complex for Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer PatientsWithdrawnNCT03465345Phase 1
• Bioequivalence Study of Metformin 1000 mg Tablets Immediate Release (IR) Versus Glucophage® 1000 mg Tablets IR In Healthy SubjectsCompletedNCT03458208Phase 1
• Bioequivalence Study of Metformin 750 mg Tablets XR Versus Glucophage® Long 750 mg Tablets XR In Normal Healthy Subjects Under Fasting and Fed ConditionsCompletedNCT03452306Phase 1
• Insulin Signaling in Skeletal MuscleWithdrawnNCT03452267Phase 2/3
• Metformin Gastrointestinal Intolerance: Measurement of Mitochondrial Complex ICompletedNCT03445702Early Phase 1
• Efficacy of Metformin in Preventing Diabetes in ChinaCompletedNCT03441750Phase 4
• IMPACT: A Randomized WOO Study of Novel Therapeutic Agents in Women Triaged to Primary Surgery for EOCCompletedNCT03378297Early Phase 1
• A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, Rosuvastatin, Metformin, Digoxin, and Nintedanib in Healthy Adult SubjectsCompletedNCT03363815Phase 1
• Pharmacokinetics of Metformin IntoleranceCompletedNCT03361878Phase 4
• Metformin Treatment for Colon CancerCompletedNCT03359681Phase 2
• Research of Exenatide for Overweight/Obese PCOS Patients With IGRCompletedNCT03352869Phase 4
• Effect of Metformin and Probiotics in Reproductive-aged Patients With Polycystic Ovary SyndromeStatus unknownNCT03336840Not applicable
• Inter- and Intra-individual Variations in Metformin Pharmacokinetics - The Importance of Genes and Drug InteractionsCompletedNCT03335423Phase 1
• The Interaction Between Metformin and Acute ExerciseCompletedNCT03329651Not applicable
• Comparison of Metformin and Insulin for Management of Gestational Diabetes MellitusCompletedNCT03320694Phase 3
• The Interaction Between Metformin and Physical TrainingCompletedNCT03316690Not applicable
• A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced MelanomaActive, not recruitingNCT03311308Phase 1
• An Assessment of Pharmacokinetic Gemigliptin and Metformin Interactions in Healthy Mexican VolunteersCompletedNCT03310749Phase 1
• Metformin Treatment on Cognitive Impairment of Schizophrenia Co-morbid Metabolic SyndromeStatus unknownNCT03271866Not applicable
• A Study to Assess the Effect of Plazomicin on the Pharmacokinetics of MetforminCompletedNCT03270553Phase 1
• Metformin Treatment of Pregnant Women With Polycystic Ovary Syndrome: a Pilot StudyCompletedNCT03259919Phase 2
• Metformin Versus Vildagliptin for Diabetic Hypertensive PatientsCompletedNCT03253562Phase 4
• The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2DCompletedNCT03246451Not applicable
• Study on Low Dose Temozolomide Plus Metformin or Placebo in Patient With Recurrent or Refractory GlioblastomaCompletedNCT03243851Phase 2
• Randomized Trial of Neo-adjuvant Chemotherapy With or Without Metformin for HER2 Positive Operable Breast CancerStatus unknownNCT03238495Phase 2
• OCP vs Metformin on Ovarian Stromal Blood Flow in PCOSCompletedNCT03236740Phase 4
• Locally Delivered Metformin and Aloe Vera for Treatment of Intrabody Defects in Chronic PeriodontitisCompletedNCT03204071Phase 2/3
• Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic PeriodontitisCompletedNCT03204058Phase 2/3
• Rituximab, Cyclophosphamide, Vincristine and Prednisone (R-CHOP) Plus Metformin in Diffuse Large-B-cell LymphomaCompletedNCT03200015Phase 2
• Impacts of PIO/MET Following Short-term Intensive Insulin Treatment in Newly Diagnosed Type 2 DiabetesStatus unknownNCT03196362Phase 4
• PRuDENTE; Diabetes Prevention Via Exercise, Nutrition and TreatmentStatus unknownNCT03194009Not applicable
• Metformin and Simvastatin in Addition to FulvestrantStatus unknownNCT03192293Phase 2
• Effect of Metformin on Exercise-induced LipolysisCompletedNCT03189732Not applicable
• Celebrex and Metformin for Postoperative Hepatocellular CarcinomaStatus unknownNCT03184493Phase 3
• Insulin Resistance and Metformin Use on Volume of Benign Thyroid NodulesCompletedNCT03183752Not applicable
• Type 2 Diabetes and Ambulatory Surgery PatientsCompletedNCT03179254Phase 4
• A Study to Evaluate the Food Effect on Drug Availability, Pharmacokinetic (PK) Properties, Safety and Tolerability of Two Different Dose Combination Therapy of Saxagliptin/Dapagliflozin/Metformin Extended-release (XR) Against Individual Component Co-administration.CompletedNCT03169959Phase 1
• Bioavailability of Disulfiram and Metformin in GlioblastomasTerminatedNCT03151772Early Phase 1
• Bioequivalence Study of Combination Tablets of Saxagliptin / Dapagliflozin / Metformin XR (Extended-release) and Dapagliflozin / Metformin XR Relative to Individual Components in Healthy SubjectsCompletedNCT03138356Phase 1
• Repurposing Metformin as Anticancer Drug: in Advanced Prostate CancerStatus unknownNCT03137186Phase 2
• Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian SyndromeStatus unknownNCT03135301Phase 3
• Adding MAraViroc &/or METformin for Hepatic Steatosis in People Living With HIVCompletedNCT03129113Phase 2/3
• Metformin Reduce the Relapse Rate on Patients With B-cell Precursor (Ph+ Negative) Acute Lymphoblastic LeukemiaCompletedNCT03118128Not applicable
• L-carnitine and Metformin in Obese PCOS Women.CompletedNCT03108963Phase 2
• Role of Metformin on Muscle Health of Older AdultsActive, not recruitingNCT03107884Early Phase 1
• Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care in Kisarawe, TanzaniaCompletedNCT03098654Not applicable
• Metformin in Intracytoplasmic Sperm Injection CyclesCompletedNCT03088631Phase 2
• Phase II Lung Metcore - Preoperative Metformin for Lung CancerCompletedNCT03086733Phase 2
• Study to Assess the Effect of Metformin Supplementation on IVF Outcome in Patients With Polycystic Ovarian Syndrome.CompletedNCT03086005Phase 3
• Failure Rate of GLyburide And Metformin Among Gestational DiabeticsWithdrawnNCT03078725Phase 4
• Metformin Plus TKI Use in Patients With Non-Small Cell Lung CarcinomaStatus unknownNCT03071705Not applicable
• Antidiabetic Effects on Intrahepatic FatCompletedNCT03068065Phase 4
• A Study To Evaluate The Safety,Tolerability, PK and PD Of DA-1241 In Healthy Male SubjectsCompletedNCT03061981Phase 1
• Metformin in Intrahepatic Cholestasis of PregnancyStatus unknownNCT03056274Phase 2/3
• Metformin With Neoadjuvant Chemoradiation to Improve Pathologic Responses in Rectal CancerCompletedNCT03053544Phase 2
• Metformin SR Tablet (DuLeNing) and Glucophage in Patients With Type 2 DiabetesCompletedNCT03039075Phase 4
• Short Term Weight Loss With Liraglutide and Metformin in Infertile Obese PCOS PatientsCompletedNCT03034941Phase 4
• Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic SyndromeTerminatedNCT03031821Phase 3
• Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in PrediabetesStatus unknownNCT03029390Phase 4
• Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory CancersCompletedNCT03017833Phase 1
• Effect of Linagliptin + Metformin vs Metformin Alone in Patients With PrediabetesCompletedNCT03004612Phase 4
• Mirena® ± Metformin as Fertility-preserving Treatment for Young Asian Women With Early Endometrial CancerStatus unknownNCT02990728Phase 2
• Extended-release vs Immediate-release Metformin in PCOS WomenStatus unknownNCT02984722Not applicable
• The Potential Hepatoprotective Effect of Metformin in Patients With Beta Thalassemia MajorStatus unknownNCT02984475Phase 4
• The PK Characteristics of the Co-administration of Metformin SR and Rosuvastatin and JLP-1310 in Healthy Male VolunteersCompletedNCT02982798Phase 1
• Fetal Hemoglobin Induction Treatment MetforminCompletedNCT02981329Early Phase 1
• The Effects of Neoadjuvant Metformin on Tumour Cell Proliferation and Tumour Progression in Pancreatic Ductal AdenocarcinomaStatus unknownNCT02978547Phase 2
• Metformin Therapy in HCV InfectionCompletedNCT02972723Phase 4
• Metformin and Dietary Restriction to Prevent Age-related Morbid Events in People With Metabolic SyndromeCompletedNCT02960711Phase 3
• The Effects of Metformin on Self-selected Exercise Intensity, Physical Fitness and Exercise-induced AMPK-activationCompletedNCT02951260Not applicable
• Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic LeukemiaCompletedNCT02948283Phase 1
• Effectiveness & Tolerability of Novel, Initial Triple Combination Therapy vs Conventional Therapy in Type 2 DiabetesStatus unknownNCT02946632Phase 3
• SAKK 08/15 - PROMET - Salvage Radiotherapy +/- Metformin for Patients With Prostate Cancer After ProstatectomyTerminatedNCT02945813Phase 2
• Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4) Inhibitor Sitagliptin in Combination With Metformin After Liragludite Induced Weight LossCompletedNCT02941445Phase 4
• Effect of Insulin Sensitization on IGF-1 Response to Growth Hormone in SGA ChildrenStatus unknownNCT02931591Not applicable
• Impact of Metformin on In Vitro Fertilization Outcomes in Overweight and Obese PCOS WomenCompletedNCT02910817Not applicable
• Low Dose Liraglutide and Metformin vs. High Dose Liraglutide Alone in Treatment of ObesityCompletedNCT02909933Phase 4
• Efficacity and Safety of Metformin XR in CKD Stage 1 to 3CompletedNCT02895750Phase 2
• Autoimmune Diabetes Accelerator Prevention TrialWithdrawnNCT02881528Phase 4
• HbA1c Variability in Type II DiabetesActive, not recruitingNCT02879409Not applicable
• Apoptotic Signaling Pathways in Rats With Endometrial HyperplasiaCompletedNCT02872818Phase 4
• The Effects of OCP and Metformin on Clinical, Hormonal, Metabolic and Ultrasonographic Characteristics in PCOSCompletedNCT02866786Phase 4
• A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted ParticipantsCompletedNCT02865668Phase 1
• A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin Extended Release Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted ParticipantsCompletedNCT02851212Phase 1
• A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release (XR) With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted ParticipantsCompletedNCT02851095Phase 1
• The Effect of Metformin on Fecundability in an ART(Assisted Reproductive Technology) Setting - the Correlation to Uterine FlowsStatus unknownNCT02848950Phase 2
• Metformin in Moderate and Severe Renal Failure (CKD 3-4): A Follow-up StudyWithdrawnNCT02848508Phase 2
• A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted ParticipantsCompletedNCT02846506Phase 1
• Metformin/Rosuvastatin Combination Therapy With in Patients With Type 2 Diabetes and DyslipidemiaCompletedNCT02827903Phase 3
• The MetNET-2 TrialStatus unknownNCT02823691Early Phase 1
• The Drug-drug Interaction of SP2086 and MetforminCompletedNCT02813863Phase 1
• Effects of Metformin Treatment on Myocardial Efficiency in Patients With Heart FailureCompletedNCT02810132Phase 2
• Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian SyndromeStatus unknownNCT02802215Phase 2/3
• The Effect of Alogliptin on Pulmonary Function in Obese Patients With Type 2 Diabetes Inadequately Controlled by Metformin MonotherapyCompletedNCT02798172Not applicable
• Metformin Pharmacokinetics in Patients With Chronic and Acute Heart FailureStatus unknownNCT02797340Phase 4
• Metformin and Core Temperature in Obese and Lean MalesCompletedNCT02783053Not applicable
• Metformin, Neo-adjuvant Temozolomide and Hypo- Accelerated Radiotherapy Followed by Adjuvant TMZ in Patients With GBMActive, not recruitingNCT02780024Phase 2
• Combination of Metformine/Inulin Versus Metformin on Prostate Benign Hyperplasia in Metabolic SyndromeCompletedNCT02778776Phase 3
• Combination of Metformin/Inulin vs Inulin on Adiponectin in Metabolic SyndromeCompletedNCT02773927Phase 3
• The Effects of Metformin on Glycemic Control and Insulin Sensitivity in Adolescents With T1DMCompletedNCT02765347Phase 4

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