Macitentan: all 56 studies that test it

Page 1 of 1. Open to participants first (3), then studies with results posted, then the rest; newest registration first within each.

• Efficacy and Mechanisms of Macitentan for Non-Coronary Obstructive AnginaRecruitingNCT07392281Early Phase 1
• Evaluation of the Efficacy of MACitentan in the Treatment of CoronaryMICrovascular Angina (MACMIC)RecruitingNCT06811831Early Phase 1
• A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other OptionRecruitingNCT05179876Phase 3
• Endothelin-1 and Cardiac Allograft Vasculopathy (CAV)CompletedNCT05373108Phase 4Results posted
• A Study of Macitentan in Japanese Pediatric Participants With Pulmonary Arterial HypertensionCompletedNCT05167825Phase 3Results posted
• A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary HypertensionTerminatedNCT04271475Phase 3Results posted
• An Upcoming Clinical Study to Measure the Safety and Impact of a Drug Called Macitentan in Teenage and Adult Fontan Patients.TerminatedNCT03775421Phase 3Results posted
• A Long Term Study to Find Out if Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular DiseaseTerminatedNCT03714815Phase 2Results posted
• Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated SubjectsCompletedNCT03153137Phase 3Results posted
• A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular DiseaseCompletedNCT03153111Phase 2Results posted
• A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)CompletedNCT02932410Phase 3Results posted
• Macitentan in Pulmonary Hypertension of Sickle Cell DiseaseTerminatedNCT02651272Phase 2Results posted
• Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device ImplantationCompletedNCT02554903Phase 2Results posted
• PORtopulmonary Hypertension Treatment wIth maCitentan - a randOmized Clinical TrialCompletedNCT02382016Phase 4Results posted
• REPAIR: Right vEntricular Remodeling in Pulmonary ArterIal hypeRtensionCompletedNCT02310672Phase 4Results posted
• A Pulmonary Arterial Hypertension Study With Macitentan to Validate the PAH-SYMPACT™ in France, Italy and SpainTerminatedNCT02081690Phase 3Results posted
• Clinical Study to Evaluate the Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) Due to Left Ventricular DysfunctionCompletedNCT02070991Phase 2Results posted
• Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary HypertensionCompletedNCT02060721Phase 2Results posted
• Clinical Study to Assess the Efficacy, Safety and Tolerability of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary HypertensionCompletedNCT02021292Phase 2Results posted
• Clinical Study of Macitentan in Patients With PAH to Psychometrically Validate PAH-SYMPACT InstrumentTerminatedNCT01847014Phase 3Results posted
• Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT InstrumentCompletedNCT01841762Phase 3Results posted
• Clinical Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger SyndromeCompletedNCT01743001Phase 3Results posted
• Clinical Study to Assess the Long-term Safety, Tolerability, and Efficacy of Macitentan in Subjects With Eisenmenger SyndromeTerminatedNCT01739400Phase 3Results posted
• Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis PatientsTerminatedNCT01474122Phase 3Results posted
• Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis PatientsCompletedNCT01474109Phase 3Results posted
• Macitentan Use in an Idiopathic Pulmonary Fibrosis Clinical StudyCompletedNCT00903331Phase 2Results posted
• Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial HypertensionCompletedNCT00667823Phase 3Results posted
• Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial HypertensionCompletedNCT00660179Phase 3Results posted
• Macitentan and Tadalafil Film-coated Tablets 10 mg/40 mg and 'PrOpsynvi®' Macitentan and Tadalafil Film-coated Tablets 10 mg/40 mgCompletedNCT06553924Phase 1
• Macitentan to Prevent PRVOWithdrawnNCT05946811Phase 3
• A Study of Macitentan in Children Below 2 Years of AgeWithdrawnNCT05731492Phase 1
• A Study of Two Macitentan Formulations in Healthy Adult ParticipantsCompletedNCT05433675Phase 1
• A Study of Two Different Test Formulations Compared to the Reference Formulation of Macitentan in Healthy Adult ParticipantsCompletedNCT05392530Phase 1
• A Study of Fixed Dose Combination of Macitentan/Tadalafil (10 mg/20 mg) Compared to the Reference Free Combination of Macitentan and Tadalafil in Healthy Adult ParticipantsCompletedNCT05236231Phase 1
• Effects of Combination Medical Therapy Followed by BPA on Right Ventricular-PA Coupling and Hemodynamics in CTEPHTerminatedNCT05140525Phase 3
• A Study of Two Macitentan Pediatric Formulations in Healthy Adult ParticipantsCompletedNCT04963439Phase 1
• Initial Dual Oral Combination Therapy Versus Standard-of-care Initial Oral Monotherapy Prior to Balloon Pulmonary Angioplasty in Patients With Inoperable Chronic Thromboembolic Pulmonary HypertensionCompletedNCT04780932Phase 2/3
• A Study of Macitentan/Tadalafil Combination Administered a Fixed-dose Combination Formulation Compared to the Reference Free Combination of Macitentan and TadalafilCompletedNCT04540744Phase 1
• A Study of Macitentan, in Healthy Japanese Male ParticipantsCompletedNCT04500808Phase 1
• Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial HypertensionActive, not recruitingNCT04273945Phase 3
• A Study of Macitentan and Tadalafil as a Fixed Dose Combination and the Free Combination in Healthy Adult ParticipantsCompletedNCT04235270Phase 1
• A 2-part Study to Investigate the Effect of Macitentan in Healthy Male ParticipantsCompletedNCT04211272Phase 1
• A Clinical Study to Find Out if Macitentan is Effective and Safe in Japanese Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH).TerminatedNCT03809650Phase 3
• CompRehensive Phenotypic Characterization of Patients With Scleroderma-Associated ILD and PHWithdrawnNCT03726398Phase 2/3
• A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Hypertension Who Were Previously Treated With Macitentan in Clinical Studies.CompletedNCT03422328Phase 3
• Clinical Study to Investigate Effect of Macitentan on Riociguat PharmacokineticsCompletedNCT03389321Phase 1
• (RIGHT HEART III Study - Right Ventricular Hemodynamic Evaluation and Response to Treatment)CompletedNCT03362047Phase 2
• Clinical Study to Investigate the Effect of Macitentan on the Concentrations of Rosuvastatin in the Blood of Healthy Male SubjectsCompletedNCT03359291Phase 1
• A Study to Compare the Macitentan-tadalafil Fixed Dose Combination Tablet Relative to the Concomitant Administration of the Reference Tablets of Macitentan and Tadalafil in Healthy SubjectsCompletedNCT03215966Phase 1
• Clinical Study Evaluating the Effects of First-line Oral cOmbination theraPy of maciTentan and tadalafIl in Patients With Newly Diagnosed pulMonary Arterial Hypertension (OPTIMA)TerminatedNCT02968901Phase 4
• Macitentan in the Treatment of Organ Rejection After Lung TransplantationWithdrawnNCT02893176Phase 4
• Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed GlioblastomaTerminatedNCT02254954Phase 1
• Extension of the Psychometric Validation Study ORCHESTRA in Patients With PAHCompletedNCT02112487Phase 3
• Study to Assess the Effect of Macitentan on the Electrocardiogram (ECG) in Healthy Male and Female SubjectsCompletedNCT02050802Phase 1
• Clinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent GlioblastomaTerminatedNCT01499251Phase 1
• Safety and Tolerability Study of Macitentan in Patients With Idiopathic Pulmonary FibrosisWithdrawnNCT01346930Phase 2

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