Drug
Letermovir clinical trials
Also written Prevymis, MK-8228 and AIC246.
- studies test it
- 39
- open now
- 21
- in phase 3
- 13
- first study started
- 2010
Keep track of what changes. Save the letermovir studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
39 studies that test it; most in 2024 (10)
| Year | Studies |
|---|---|
| 2010 | 1 |
| 2014 | 1 |
| 2018 | 1 |
| 2019 | 4 |
| 2020 | 1 |
| 2021 | 2 |
| 2022 | 3 |
| 2023 | 7 |
| 2024 | 10 |
| 2025 | 6 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 3
- Phase 2
- 14
- Phase 3
- 13
- Phase 4
- 6
- No phase
- 4
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 8 · Other 31
Merck Sharp & Dohme LLC (7) · Assistance Publique - Hôpitaux de Paris (3) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Tufts Medical Center (2) · University of Wisconsin, Madison (2) · M.D. Anderson Cancer Center (2) · University of Pennsylvania (1) · Ruijin Hospital (1)
Studies
Open first, then newest update. How each study uses letermovir is read from its arms, and is right about nine times in ten.
Testing it · 39
- A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)RecruitingPhase 1Merck Sharp & Dohme LLCNCT07199465Written as Letermovir
- A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric PatientsRecruitingPhase 3Children's Oncology GroupNCT05711667Written as Letermovir
- Valganciclovir vs. Letermovir for CMV Prophylaxis in Heart TransplantRecruitingPhase 2/3Columbia UniversityNCT07079735Written as Letermovir
- Letermovir for R+ StudyNot yet recruitingPhase 4University of Wisconsin, MadisonNCT07706166Written as Letermovir
- Single Arm Pilot Trial of Letermovir for CMV Prophy in CAR T CellRecruitingPhase 2M.D. Anderson Cancer CenterNCT06575374Written as Letermovir
- CMV-TCIP Directed Letermovir Prophylaxis After Allo-SCTRecruitingPhase 2University of California, IrvineNCT06453460Written as Letermovir
- The Use of Cytomegalovirus Cell Mediated Immunity to Optimize the Duration of Letermovir Prophylaxis in Hematopoietic Cell Transplant RecipientsRecruitingNot applicableM.D. Anderson Cancer CenterNCT06639854Written as Letermovir
- Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant RecipientsRecruitingPhase 3University of Wisconsin, MadisonNCT06407232Written as Letermovir
- Letermovir vs Valganciclovir in CMV R+ Kidney TransplantNot yet recruitingPhase 4Elisabeth KincaideNCT07571135Written as Letermovir
- Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Versus ValaciclovirRecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT05446571Written as Letermovir
- Letermovir Prophylaxis in Children With EBV-Positive T/NK-Cell Lymphoproliferative Disease and Refractory/Relapsed EBV-Associated Hemophagocytic LymphohistiocytosisRecruitingNot applicableBeijing Children's HospitalNCT07488728Written as Letermovir
- Combination Letermovir and Standard of Care Antiviral for Enhanced Antiviral Response in Cytomegalovirus Infection in Lung Transplant RecipientsRecruitingPhase 4University Health Network, TorontoNCT07235683Written as Letermovir
- Letermovir-based Dual Therapy for Treatment of Cytomegalovirus InfectionsRecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT06334497Written as Letermovir
- Phase II Trials of Letermovir Prophylaxis in Patients With RRMM Undergoing Elranatamab TherapyRecruitingPhase 2Seoul National University HospitalNCT06920251Written as Letermovir
- Pharmacokinetics of Oral Letermovir in Adults With End-Stage Kidney Disease With or Without HaemodialysisNot yet recruitingPhase 1Jason A RobertsNCT07101055Written as Letermovir 480 mg [PREVYMIS]
- Letermovir for Secondary Prophylaxis in Solid Organ Transplant RecipientsRecruitingPhase 4Tufts Medical CenterNCT05626530Written as Letermovir
- Clinical Trial to Evaluate the Effects of Letermovir Prophylaxis on T-cell Immune Activation in Participants With Treated HIV-1 InfectionNot yet recruitingPhase 2University College, LondonNCT06626555Written as Letermovir
- Evaluation of the Prophylactic Use of Letermovir in Kidney Transplant Recipients at Risk of Cytomegalovirus InfectionNot yet recruitingPhase 3Hospital do Rim e HipertensãoNCT06341686Written as Letermovir 480 MG
- Efficacy of Letermovir in Preventing Cytomegalovirus (CMV) Infection in Lung Transplant Recipients vs. Valganciclovir.Not yet recruitingPhase 2Maimónides Biomedical Research Institute of CórdobaNCT06057194Written as Letermovir 240 mg Oral Tablet
- Letermovir Prophylaxis for Cytomegalovirus (CMV) in Patients With Graft-versus-host DiseaseNot yet recruitingPhase 2Rabin Medical CenterNCT05969743Written as Letermovir
See all 39 studies that test letermovir →
Given in every arm · 2 — letermovir is usual care beside what is tested
- A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell TransplantRecruitingPhase 1City of Hope Medical CenterNCT07020533Written as Letermovir
- Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell TransplantationActive, not recruitingPhase 2City of Hope Medical CenterNCT04060277Written as Letermovir
As the comparator · 1 — what is tested is compared with letermovir
Codes
What other systems call letermovir · ClinicalTrials.gg INT000006
- MeSH (NLM) C000588473letermovirConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 1H09Y5WO1FLETERMOVIRConfirmed FDA, NLM, Wikidata
- RxNorm 1988648Confirmed FDA, Wikidata
- Wikidata Q15409407letermovirConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C115099LetermovirOne source FDA
- DrugBank DB12070One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000588473 | letermovir | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 1H09Y5WO1F | LETERMOVIR | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1988648 | — | Confirmed FDA, Wikidata |
| Wikidata | Q15409407 | letermovir | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C115099 | Letermovir | One source FDA |
| DrugBank | DB12070 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.