Lemborexant: all 50 studies that test it

Page 1 of 1. Open to participants first (15), then studies with results posted, then the rest; newest registration first within each.

• How Well and Safely Does Lemborexant Work for People Who Wake up at Night to Urinate (LENS)Not yet recruitingNCT07840638Phase 4
• Lemborexant on Perioperative Sleep Quality in Patients Undergoing Thoracoscopic SurgeryNot yet recruitingNCT07811401Phase 2
• Lemborexant for Cannabis Use DisorderNot yet recruitingNCT07802990Phase 1/2
• The Optimal One-Month Dosing of Lemborexant for Moderate Obstructive Sleep Apnea (OSA) Patients With Low Arousal ThresholdNot yet recruitingNCT07683442Phase 1/2
• Lemborexant for Sleep and Delirium Prevention in Elderly ICU PatientsRecruitingNCT07407400Phase 4
• Effects of Lemborexant on Motor-sleep Comorbidity in Parkinson's DiseaseNot yet recruitingNCT07384429Phase 4
• Effects of Lemborexant on Insomnia and Its Relationship to Mood and Behavior on Opioid Use Disorder SubjectsRecruitingNCT06981195Phase 2
• Effects of Eszopiclone and Lemborexant in People With OSA With a Low Arousal Threshold Who Have Difficulty SleepingRecruitingNCT06928766Phase 2
• A Dual Orexin Receptor Antagonist to Reduce Biomarkers of Neurodegeneration in Adults With Insomnia.RecruitingNCT06823752Phase 2
• Efficacy of CBT-I and Lemborexant Medication for Different Subtypes of Chronic InsomniaRecruitingNCT06779149Not applicable
• Lemborexant to Prevent Post-operative Delirium in Cardiac Surgery PatientsNot yet recruitingNCT06648681Phase 2
• Lemborexant on Improving Sleep Quality Among Hospital Rotating Shift WorkersRecruitingNCT06496282Phase 3
• DORA and LP in Alzheimer's Disease BiomarkersRecruitingNCT06274528Phase 2
• Lemborexant Treatment of Insomnia Linked to EpilepsyRecruitingNCT06262594Phase 3
• Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 TrialRecruitingNCT06093126Phase 4
• A Study to Assess the Pharmacodynamics of Lemborexant in Korean Participants With Insomnia DisorderCompletedNCT05594589Phase 2Results posted
• Lemborexant Augmentation of Naltrexone for Alcohol Craving and SleepCompletedNCT05458609Phase 3Results posted
• Lemborexant Shift Work Treatment StudyCompletedNCT05344443Phase 4Results posted
• Drug-drug Interaction Study of Lemborexant as an Adjunctive Treatment for Buprenorphine/Naloxone for Opioid Use DisorderCompletedNCT04818086Phase 1/2Results posted
• A Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Participants With Moderate to Severe Obstructive Sleep Apnea, and in Adult and Elderly Participants With Moderate to Severe Chronic Obstructive Pulmonary DiseaseCompletedNCT04647383Phase 1Results posted
• A Study of Lemborexant in Chinese Participants With Insomnia DisorderCompletedNCT04549168Phase 3Results posted
• A Study to Evaluate Next-Dose Transition From Zolpidem to Lemborexant (LEM) for the Treatment of InsomniaCompletedNCT04009577Phase 3Results posted
• Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Healthy Subjects and Adult and Elderly Subjects With Mild Obstructive Sleep ApneaCompletedNCT03471871Phase 1Results posted
• Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Normal Renal Function or With Severe Renal ImpairmentCompletedNCT03443063Phase 1Results posted
• Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Mild and Moderate Hepatic Impairment Compared to Healthy SubjectsCompletedNCT03440424Phase 1Results posted
• Study of Lemborexant for Irregular Sleep-Wake Rhythm Disorder and Mild to Moderate Alzheimer's Disease DementiaCompletedNCT03001557Phase 2Results posted
• Long-term Study of Lemborexant in Insomnia Disorder (SUNRISE 2)CompletedNCT02952820Phase 3Results posted
• Study of the Efficacy and Safety of Lemborexant in Subjects 55 Years and Older With Insomnia Disorder (SUNRISE 1)CompletedNCT02783729Phase 3Results posted
• Study to Evaluate the Effect of 2 Dosage Strengths of Lemborexant (E2006) on a Multiple Sleep Latency Test in Participants With Insomnia DisorderCompletedNCT02350309Phase 1Results posted
• A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Bayesian Adaptive Randomization Design, Dose Response Study of the Efficacy of E2006 in Adults and Elderly Subjects With Chronic InsomniaCompletedNCT01995838Phase 2Results posted
• A 2-Part Single Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006CompletedNCT01463098Phase 1Results posted
• Efficacy and Safety of Lemborexant for Patients With Cirrhosis and Sleep ProblemsCompletedNCT07480096Phase 2
• Lemborexant for the Treatment of Residual Insomnia in Major Depressive Disorder (MDD)TerminatedNCT06843187Phase 2
• The Effects of Lemborexant on the Ability to Sleep During DaytimeTerminatedNCT06231641Phase 2
• Effects of Lemborexant as a Treatment for Moderate-to-severe OSA Patients With Low Arousal ThresholdCompletedNCT05763329Phase 1/2
• Acute Effect of Lemborexant on CSF Amyloid-Beta and TauWithdrawnNCT05728736Phase 2
• Lemborexant in Delayed Sleep Phase SyndromeCompletedNCT05463861Phase 4
• A Study to Evaluate Lemborexant in Milk of Healthy Lactating WomenCompletedNCT04890561Phase 1
• An Open-label, Multicenter Study to Evaluate the Efficacy and Safety of Transitioning to Lemborexant in Japanese Subjects With InsomniaCompletedNCT04742699Phase 4
• A Single and Multiple Dose Study of Lemborexant in Healthy Chinese ParticipantsCompletedNCT04555733Phase 1
• Study of Lemborexant-Alcohol Interaction in Healthy SubjectsCompletedNCT03483636Phase 1
• Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Contraceptive, Famotidine, or Fluconazole in Healthy SubjectsCompletedNCT03451110Phase 1
• A Study to Determine the Abuse Potential of Single Oral Doses of Lemborexant Compared to Zolpidem, Suvorexant and Placebo in Healthy, Non-Dependent, Recreational Sedative UsersCompletedNCT03158025Phase 1
• Study to Evaluate the Effect of Lemborexant Versus Placebo on Driving Performance in Healthy Adult and Elderly SubjectsCompletedNCT02583451Phase 1
• A Study to Determine the Effect of a High-Fat Meal on the Rate and Extent of E2006 Absorption in Healthy SubjectsCompletedNCT02089412Phase 1
• A 2-Part Study to Assess Potential Metabolism-Based Drug-Drug Interactions of E2006 When Coadministered With Itraconazole, Rifampin, Midazolam, or BupropionCompletedNCT02085967Phase 1
• An Open-label, Single-dose Study to Determine the Metabolism and Excretion of [14C]E2006 in Healthy Male SubjectsCompletedNCT02046213Phase 1
• A Two-Part Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006 in Healthy Japanese and White SubjectsCompletedNCT02039089Phase 1
• Open-Label Study of Bioavailability of E2006 Tablet Versus Capsule FormulationsCompletedNCT01673880Phase 1
• 2-Part Multiple Ascending Dose Study for Safety and Pharmacokinetics in Healthy and Elderly SubjectsCompletedNCT01673451Phase 1

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