Janus Kinase Inhibitors: all 1,428 studies that test it
Page 9 of 15. Open to participants first (328), then studies with results posted, then the rest; newest registration first within each.
- Three Dose Levels of CP-690,550 Monotherapy Versus Placebo, Administered Orally Twice Daily (BID) for 6 WeeksCompletedNCT00147498Phase 2Results posted
- A 6-Month Study Of CP-690,550 Versus Tacrolimus In Kidney Transplant PatientsCompletedNCT00106639Phase 2Results posted
- Baricitinib for Central Centrifugal Cicatricial Alopecia in Adults of African DescentCompletedNCT07843732Phase 2
- Tofacitinib in the Treatment of IgG4 Related DiseasesCompletedNCT07827469Not applicable
- Topical Delgocitinib for Facial VitiligoActive, not recruitingNCT07820098Phase 2
- An Interventional Study of Upadacitinib Extended-Release Tablets in Patients With Refractory UveitisActive, not recruitingNCT07773623Phase 4
- A 24-Week Real-World Study of Upadacitinib in Moderate-to-Severe Hidradenitis SuppurativaActive, not recruitingNCT07727889Phase 2
- QT Interval/Corrected QT Interval (QT/QTc) Clinical Study to Evaluate the Cardiac Safety of TQ05105 Tablets in Healthy ParticipantsActive, not recruitingNCT07708272Phase 1
- Assessment of Interleukin-15 and Interferon Gamma in Alopecia Areata Before and After Baricitinib.CompletedNCT07645430Not applicable
- Ivarmacitinib for Refractory Behcet's SyndromeWithdrawnNCT07634848Phase 2
- Study to Evaluate the Effect of Rabeprazole Sodium Enteric-coated Tablets on the Pharmacokinetics of TQ05105 TabletsActive, not recruitingNCT07608666Phase 1
- A Study to Evaluate Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult ParticipantsCompletedNCT07588139Phase 1
- Efficacy of Tofacitinib on Skin Thickening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With MethotrexateCompletedNCT07472166Phase 4
- A Phase 1 Study of the Safety and How the Body Processes ABBV-722 and Upadacitinib After Multiple Oral Doses in Healthy Adult ParticipantsCompletedNCT07425899Phase 1
- Pacritinib With Aza for Upfront Myelodysplastic SyndromeWithdrawnNCT07387354Phase 1/2
- An Investigational Study to Evaluate the Cardiac Safety Assessment (TQTc Study) of ESK-001CompletedNCT07378579Phase 1
- Comparative Effectiveness of Ruxolitinib Monotherapy Versus Its Combination With Tacrolimus and Corticosteroids in the Management of Vitiligo: A Randomized Controlled TrialCompletedNCT07368673Phase 4
- Study of Pelabresib add-on to Ruxolitinib in Japanese Adult Patients With MyelofibrosisActive, not recruitingNCT07340138Phase 1
- A Clinical Trial of Mass Balance of [14C] TQ05105 in Healthy Chinese SubjectsCompletedNCT07293390Phase 1
- A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.Active, not recruitingNCT07228390Phase 2
- A Randomized, Double-blind, Placebo-controlled Phase I Clinical Trial to Evaluate the Safety and Pharmacokinetic Profile of Single and Multiple Dose Escalation Topical Dermal Administration of SHR0302 Alkali Gel in Healthy SubjectsCompletedNCT07098117Phase 1
- Upadacitinib for Refractory Behcet's SyndromeCompletedNCT07080346Phase 2
- Efficacy of Oral Tofacitinib in Combination of Narrow Band UVB in Treatment of VitiligoActive, not recruitingNCT07044141Phase 1
- A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants in Japan With Alopecia AreataActive, not recruitingNCT07023302Phase 3
- Efficacy and Tolerability of Deucravacitinib in the Management of Palmoplantar PustulosisTerminatedNCT07000630Not applicable
- A Study Comparing Zasocitinib (TAK-279) With Deucravacitinib in Adults With Plaque PsoriasisCompletedNCT06973291Phase 3
- A Study of Filgotinib 200 mg in Korean Participants With Moderately to Severely Active Ulcerative Colitis Under Routine Clinical PracticeActive, not recruitingNCT06964113Phase 4
- An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal FunctionCompletedNCT06962774Phase 1
- Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1)Active, not recruitingNCT06959225Phase 3
- Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)Active, not recruitingNCT06958211Phase 3
- An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver DamageCompletedNCT06952634Phase 1
- A Study to Assess the Efficacy and Safety of PG-011 Nasal Spray in Adults With Moderate to Severe Seasonal Allergic RhinitisCompletedNCT06837233Phase 2
- A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic DermatitisActive, not recruitingNCT06832618Phase 3
- Ritlecitinib (PF-06651600) in Participants With Chronic Spontaneous UrticariaWithdrawnNCT06795373Phase 2
- A Study of Interaction of Zasocitinib (TAK-279) With Other Medicines in Healthy AdultsCompletedNCT06793943Phase 1
- A Trial of SHR0302Base in Patients With VitiligoActive, not recruitingNCT06790862Phase 2
- Upadacitinib for Prurigo NodularisTerminatedNCT06773403Phase 4
- CART123 + Ruxolitinib in Relapsed/Refractory AMLActive, not recruitingNCT06768476Phase 1
- Use of Selective JAK Inhibitor in ILD and Skin Tightness of Systemic Sclerosis Versus MMFCompletedNCT06758947Phase 3
- Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic AnemiaActive, not recruitingNCT06752694Phase 2
- Study to Evaluate the Pharmacokinetics and Pharmacodynamics of AZD4604 Given Via the Turbuhaler® Device in Adults With Mild Asthma.CompletedNCT06732882Phase 1
- Tyrosine Kinase 2 (TYK2) for GA and CSWithdrawnNCT06725264Phase 2
- Safety and Efficacy of Upadacitinib in Combination With Topical Corticosteroids in Children From 2 to Less Than 12 Years of Age in Japan With Moderate to Severe Atopic DermatitisActive, not recruitingNCT06701331Phase 3
- Upfront Ruxolitinib for Chronic Graft-vs-host DiseaseTerminatedNCT06695507Phase 1
- A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic MedicinesActive, not recruitingNCT06671496Phase 3
- Baricitinib for Refractory Takayasu ArteritisCompletedNCT06662721Phase 2
- A Study of Filgotinib in Korean Participants With Rheumatoid ArthritisCompletedNCT06625242Phase 4
- A Phase 2 Study of INCB57643 (BET Inhibitor) in Combination With Ruxolitinib in JAK Inhibitor-naïve Patients With MyelofibrosisWithdrawnNCT06619522Phase 2
- To Evaluate the Pharmacokinetics and Safety of TQ05105 Tablet in Renal Impairment SubjectsCompletedNCT06598956Phase 1
- Study to Investigate the Efficacy of Abrocitinib in Adult Participants With Severe Fatigue From Post COVID Condition/Long COVIDActive, not recruitingNCT06597396Phase 2
- A Study in Patients With Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001CompletedNCT06588738Phase 3
- A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque PsoriasisCompletedNCT06586112Phase 3
- Study to Evaluate Drug Levels of Various Solid Gastro-retentive Formulations of Deucravacitinib (BMS-986165) in Healthy ParticipantsCompletedNCT06566768Phase 1
- A Study to Evaluate the Bioequivalence of Ruxolitinib Extended Release (XR) Tablets With Ruxolitinib Immediate Release (IR) Tablets Administered Orally in Healthy ParticipantsCompletedNCT06555081Phase 1
- A Study of TAK-279 in Participants With Moderate-to-Severe Plaque PsoriasisActive, not recruitingNCT06550076Phase 3
- Efficacy and Safety of Baricitinib in the Post-intracerebral Hemorrhage Pulmonary InjuryActive, not recruitingNCT06548802Phase 1/2
- Retinol Binding Protein 4 Protein in Alopecia Areata Treated With BarcitinibActive, not recruitingNCT06545110Phase 1
- Deucravacitinib RosaceaWithdrawnNCT06532136Phase 2
- A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled AZD4604 in Healthy Japanese and Chinese Participants.CompletedNCT06519968Phase 1
- A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)Active, not recruitingNCT06516965Phase 3
- A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)Active, not recruitingNCT06516952Phase 3
- Study of Bemcentinib Plus Pacritinib In Patients With Advanced Lung AdenocarcinomaTerminatedNCT06516887Phase 1/2
- AZD4205 in Relapsed or Refractory Peripheral T Cell Lymphoma (JACKPOT27)CompletedNCT06511895Phase 2
- AZD4205 in Peripheral T Cell Lymphoma Following First-Line Therapy (JACKPOT26)CompletedNCT06511869Phase 2
- A Study to Evaluate Skin and Plasma Pharmacokinetic of Multiple Doses of Povorcitinib After Oral Administration in Healthy ParticipantsCompletedNCT06505265Phase 1
- Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With HemoblastosisActive, not recruitingNCT06475820Phase 2/3
- Study of Efficacy and Safety of Ruxolitinib in Patients With Grade II to IV Steroid-refractory Acute Graft vs. Host DiseaseActive, not recruitingNCT06462469Phase 4
- A Study to Evaluate the Effect of Povorcitinib on the QT/QTc Interval in Healthy ParticipantsCompletedNCT06441318Phase 1
- Phase II Study to Evaluate the Effect of AZD4604 on Airway Inflammation and Biomarkers in Adults With AsthmaCompletedNCT06435273Phase 2
- A 12-Week Open-Label Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Skin-Predominant DermatomyositisCompletedNCT06433999Phase 2
- RVU120 in Patients With Intermediate or High-risk, Primary or Secondary MyelofibrosisTerminatedNCT06397313Phase 2
- The Efficacy and Safety of Tofacitinib in Patients With Glucocorticoid Resistant ICIs-related MyocarditisCompletedNCT06393972Phase 2
- A Study to Assess the Effect of Upadacitinib in Atopic Dermatitis-induced Sleep Disturbance in Adults With Moderate to Severe Atopic DermatitisWithdrawnNCT06390722Phase 3
- A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to DupilumabActive, not recruitingNCT06389136Phase 3
- TQ05105 Tablet for Myelofibrosis Treatment in Ruxolitinib-Resistant or Intolerant PatientsTerminatedNCT06388759Phase 1
- A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host DiseaseActive, not recruitingNCT06388564Phase 2
- A Phase I Clinical Study of Flonoltinib Maleate Tablets in Healthy SubjectsCompletedNCT06387966Phase 1
- A Study to Evaluate the Drug Interaction Between Povorcitinib and the Oral Contraceptive Levonorgestrel/Ethinyl Estradiol in Healthy Adult FemalesCompletedNCT06380205Phase 1
- A Study to Learn About How Different Forms of the Study Medicine Called Ritlecitinib Pass the Intestines of Healthy Male Adults When Taken With or Without FoodCompletedNCT06369454Phase 1
- A Study to Learn How Safe and Effective Risankizumab is When Compared to Deucravacitinib to Treat Participants With Moderate Plaque Psoriasis and Who Need to Try Systemic Treatment (Works Throughout the Whole Body)CompletedNCT06333860Phase 4
- Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's DiseaseActive, not recruitingNCT06332534Phase 3
- Vitiligo Treatment by Targeting TYK2 Mediated ResponsesActive, not recruitingNCT06327321Phase 2
- A Study of TAK-279 in Adult Participants With Generalized Pustular Psoriasis or Erythrodermic PsoriasisCompletedNCT06323356Phase 3
- A Study to Evaluate the Relative Bioavailability of Ruxolitinib Extended Release (XR) Tablets Compared With Ruxolitinib Immediate Release (IR) Tablets Administered Orally in Healthy Participants.CompletedNCT06310304Phase 1
- Tofacitinib in the Treatment of Refractory Axial Spondyloarthritis Patients: A Dose Escalation StudyCompletedNCT06310057Phase 4
- A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21)CompletedNCT06295432Phase 2
- A Study of the Interaction of Other Drugs With TAK-279 in Healthy AdultsCompletedNCT06290050Phase 1
- Efficacy, Safety, and Tolerability of Abrocitinib in Subjects With Moderate to Severe Chronic Hand Eczema Refractory to Corticosteroid TherapyCompletedNCT06283550Phase 2
- TYK2 Inhibition in Paradoxical PsoriasisTerminatedNCT06281106Phase 2/3
- Efficacy of Oral Tofacitinib in Moderate to Severe Alopecia Areata, Totalis and Universalis at Tertiary Care Hospital, Karachi.CompletedNCT06278402Phase 3
- A Phase 3 Study of LNK01001 Capsule in Subjects With Moderate to Severe Atopic Dermatitis.CompletedNCT06277245Phase 3
- A Study of LNK01001 Capsule in Subjects With Active Rheumatoid Arthritis (COURAGE-RA)Active, not recruitingNCT06276998Phase 3
- A Study of TAK-279 in Healthy Adults on the Effect on ECG MeasurementsCompletedNCT06258265Phase 1
- A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative ColitisActive, not recruitingNCT06254950Phase 2
- A Clinical Trial of TQ05105 Tablets Combined With TQB3909 Tablets in the Treatment of Myelofibrosis (MF)TerminatedNCT06245941Phase 1/2
- A Study to Evaluate the Safety and Efficacy of Baricitinib in the Treatment of Frontal Fibrosing Alopecia (FFA)Active, not recruitingNCT06240351Phase 4
- Study to Measure Filgotinib in the Blood of Children and Teenagers With Arthritis Taking Filgotinib (SCALESIA)TerminatedNCT06222034Phase 1
- A Study to Evaluate the Safety and Tolerability of Maximal Use Ruxolitinib CreamCompletedNCT06213831Phase 1
- A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of INCB160058 When Administered Orally to Healthy Adult ParticipantCompletedNCT06213818Phase 1
- A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis SuppurativaActive, not recruitingNCT06212999Phase 3