Insulin degludec: all 127 studies that test it

Page 1 of 2. Open to participants first (6), then studies with results posted, then the rest; newest registration first within each.

• Regimen Transition After Short-Term Intensive Insulin Therapy in Type 2 DiabetesNot yet recruitingNCT07173712Phase 4
• Comparison Study of Insulin GZR4 With Insulin DegludecRecruitingNCT07146347Phase 1
• A Trial Investigating the Efficacy and Safety of Insulin Degludec/Liraglutide Injection in Subjects With Type 2 DiabetesNot yet recruitingNCT06559722Phase 3
• A Trial to Investigate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide in Healthy Chinese SubjectsRecruitingNCT06449703Phase 1
• Research on Optimal Strategy of Hypoglycemic Therapy for Cirrhosis With DiabetesRecruitingNCT05641337Phase 3
• A Clinical Study of Insulin Degludec Injection in Subjects With Type 2 DiabetesRecruitingNCT04955834Phase 3
• Afrezza With Basal Combination (ABC): Afrezza® Combined With AID Pump or Insulin Degludec in Adults With Type 1 DiabetesCompletedNCT05243628Phase 4Results posted
• A Research Study to Compare Two Types of Insulin, a New Insulin, Insulin Icodec and an Available Insulin, Insulin Degludec, in People With Type 2 Diabetes Who Have Not Used Insulin Before (ONWARDS 3)CompletedNCT04795531Phase 3Results posted
• A Study of LY900014 and Insulin Degludec in Participants With Type 1 DiabetesCompletedNCT04585776Phase 2Results posted
• A Research Study to Compare the Effect of Insulin Degludec and Insulin Glargine on Blood Sugar Levels in People With Type 2 Diabetes - the SWITCH PRO StudyCompletedNCT03687827Phase 4Results posted
• Comparison of Insulin Degludec With Insulin Glargine U100 for Adults With Type 1 Diabetes Crossing Multiple Time Zones.CompletedNCT03668808Phase 4Results posted
• Research Study Comparing Insulin Degludec to Insulin Detemir, Together With Insulin Aspart, in Pregnant Women With Type 1 DiabetesCompletedNCT03377699Phase 3Results posted
• Insulin Degludec and Glargine U100 for Management of Hospitalized and Discharged Patients With Type 2 DiabetesCompletedNCT03336528Phase 4Results posted
• A Trial Comparing Insulin Degludec/Liraglutide and Insulin Degludec in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Therapy and Metformin With or Without One Other Oral Antidiabetic Drug (OAD)CompletedNCT03175120Phase 3Results posted
• A Trial Comparing Insulin Degludec/Liraglutide, Insulin Degludec, and Liraglutide in Chinese Subjects With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs (OADs)CompletedNCT03172494Phase 3Results posted
• A Trial Comparing the Efficacy and Safety of Insulin Degludec and Insulin Glargine 300 Units/mL in Subjects With Type 2 Diabetes Mellitus Inadequately Treated With Basal Insulin With or Without Oral Antidiabetic DrugsCompletedNCT03078478Phase 3Results posted
• A Double-blinded Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec Both in Combination With Metformin in Japanese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal or Pre-mix/Combination Insulin Therapy and Oral Anti-diabetic DrugsCompletedNCT02911948Phase 3Results posted
• A 38 Week Trial Comparing Effect and Safety of Insulin Degludec/Insulin Aspart vs. Insulin Glargine Plus Insulin Aspart in Subjects With Type 2 Diabetes Treated With Basal Insulin With or Without Oral Antidiabetic Treatment in Need of Treatment IntensificationCompletedNCT02906917Phase 3Results posted
• A Clinical Trial Comparing Glycaemic Control and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Insulin Glargine (IGlar) as add-on Therapy to SGLT2i in Subjects With Type 2 Diabetes MellitusCompletedNCT02773368Phase 3Results posted
• Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart and BIAsp 30 in Subjects With Type 2 DiabetesCompletedNCT02762578Phase 3Results posted
• Effect of Insulin Degludec Versus Insulin Glargine on Glycemic Variability in Patients With Type 2 Diabetes MellitusCompletedNCT02680457Phase 4Results posted
• Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart Twice Daily and Biphasic Insulin Aspart Twice Daily in Subjects With Type 2 Diabetes Mellitus Before, During and After RamadanCompletedNCT02648217Phase 3Results posted
• A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Japanese Subjects With Type 2 Diabetes Mellitus.CompletedNCT02607306Phase 3Results posted
• A 104 Week Clinical Trial Comparing Long Term Glycaemic Control of Insulin Degludec/Liraglutide (IDegLira) Versus Insulin Glargine Therapy in Subjects With Type 2 Diabetes MellitusCompletedNCT02501161Phase 3Results posted
• A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes MellitusCompletedNCT02420262Phase 3Results posted
• A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) in Subjects With Type 2 Diabetes Mellitus Using Two Different Titration AlgorithmsCompletedNCT02298192Phase 3Results posted
• A Trial Comparing the Safety and Efficacy of Insulin Degludec and Insulin Glargine, Both With Insulin Aspart as Mealtime Insulin in Subjects With Type 1 DiabetesCompletedNCT02034513Phase 3Results posted
• A Trial Comparing the Safety and Efficacy of Insulin Degludec and Insulin Glargine, With or Without OADs in Subjects With Type 2 DiabetesCompletedNCT02030600Phase 3Results posted
• A Trial Comparing Cardiovascular Safety of Insulin Degludec Versus Insulin Glargine in Subjects With Type 2 Diabetes at High Risk of Cardiovascular EventsCompletedNCT01959529Phase 3Results posted
• A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide Versus Insulin Glargine in Subjects With Type 2 Diabetes MellitusCompletedNCT01952145Phase 3Results posted
• A Trial Investigating the Efficacy and Safety of Flexible vs. Fixed Dosing and Simple vs. Stepwise Titration With Once Daily (OD) Insulin Degludec in Inadequately Treated Subjects With Type 2 DiabetesCompletedNCT01880736Phase 3Results posted
• A Trial Comparing Efficacy and Safety of Insulin Degludec and Insulin Glargine in Insulin naïve Subjects With Type 2 DiabetesCompletedNCT01849289Phase 3Results posted
• A Trial Investigating the Efficacy and Safety of Insulin Degludec/Insulin Aspart Once Daily Plus Insulin Aspart for the Remaining Meals Versus Insulin Detemir Once or Twice Daily Plus Meal Time Insulin Aspart in Children and Adolescents With Type 1 Diabetes MellitusCompletedNCT01835431Phase 3Results posted
• A Randomised Trial Comparing Efficacy and Safety After Intensification With Either Insulin Aspart Once Daily as add-on or Changing to Basal Bolus Treatment With Insulin Degludec and Insulin Aspart in Subjects With Type 2 Diabetes Previously Treated With Insulin Degludec/Insulin Aspart Twice DailyCompletedNCT01814137Phase 3Results posted
• A 26-week Trial Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart BID and Insulin Degludec OD Plus Insulin Aspart in Subjects With Type 2 Diabetes Mellitus Treated With Basal Insulin in Need of Treatment Intensification With Mealtime InsulinCompletedNCT01713530Phase 3Results posted
• Comparison of the Efficacy and Safety of Two Different Dose Adjustment Regimens for Insulin Degludec/Insulin Aspart in Subjects With Type 2 Diabetes Mellitus Previously Treated With Insulin GlargineCompletedNCT01680341Phase 3Results posted
• The Efficacy of Insulin Degludec/Liraglutide in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on GLP-1 Receptor Agonist and OAD TherapyCompletedNCT01676116Phase 3Results posted
• The Effect of Insulin Degludec in Combination With Liraglutide and Metformin in Subjects With Type 2 Diabetes Qualifying for Treatment IntensificationCompletedNCT01664247Phase 3Results posted
• The Efficacy of Insulin Degludec/Liraglutide as add-on Therapy in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on Sulphonylurea With or Without Metformin TherapyCompletedNCT01618162Phase 3Results posted
• A Trial Comparing the Efficacy, Patient-reported Outcomes and Safety of Insulin Degludec 200 U/mL vs Insulin Glargine in Subjects With Type 2 Diabetes Mellitus Requiring High-dose InsulinCompletedNCT01570751Phase 3Results posted
• A Trial Comparing the Efficacy of Insulin Degludec With Insulin Glargine on Glycaemic Control Using Continuous Glucose Monitoring in Patients With Type 1 DiabetesCompletedNCT01569841Phase 3Results posted
• A Trial Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart and BIAsp 30 in Insulin naïve Subjects With Type 2 DiabetesCompletedNCT01513590Phase 3Results posted
• A Trial Investigating the Efficacy and Safety of Insulin Degludec in Children and Adolescents With Type 1 Diabetes MellitusCompletedNCT01513473Phase 3Results posted
• A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec in Subjects With Type 2 DiabetesCompletedNCT01392573Phase 3Results posted
• Efficacy and Safety of Insulin Degludec/Insulin Aspart in Insulin-naïve Subjects With Type 2 Diabetes Using Two Dosing RegimensCompletedNCT01365507Phase 3Results posted
• Comparison of Two Insulin Degludec Formulations in Subjects With Type 2 Diabetes MellitusCompletedNCT01364428Phase 3Results posted
• Dual Action of Liraglutide and Insulin Degludec in Type 2 Diabetes: A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Subjects With Type 2 DiabetesCompletedNCT01336023Phase 3Results posted
• Comparing the Efficacy and Safety of NN1250 Once Daily When Titrated Using 2 Different Algorithms in Insulin naïve Subjects With Type 2 Diabetes MellitusCompletedNCT01326026Phase 3Results posted
• Comparison of NN5401 With Insulin Glargine in Insulin Naive Subjects With Type 2 DiabetesCompletedNCT01272193Phase 3Results posted
• Switching From Insulin Glargine to Insulin Degludec in Subjects With Type 2 Diabetes Mellitus (BEGIN™)CompletedNCT01135992Phase 3Results posted
• Comparison of NN1250 With Insulin Glargine in Type 1 DiabetesCompletedNCT01079234Phase 3Results posted
• Comparison of NN1250 With Insulin Glargine in Subjects With Type 2 DiabetesCompletedNCT01076647Phase 3Results posted
• Comparison of NN1250 With Insulin Glargine in Subjects With Type 2 DiabetesCompletedNCT01068678Phase 3Results posted
• Comparison of NN1250 With Insulin Glargine in Subjects With Type 2 DiabetesCompletedNCT01068665Phase 3Results posted
• A Pan Asian Trial Comparing Efficacy and Safety of NN5401 and Biphasic Insulin Aspart 30 in Type 2 DiabetesCompletedNCT01059812Phase 3Results posted
• Comparison of NN1250 Versus Insulin Glargine in Subjects With Type 2 DiabetesCompletedNCT01059799Phase 3Results posted
• Comparison of NN1250 With Sitagliptin in Subjects With Type 2 Diabetes Never Treated With InsulinCompletedNCT01046110Phase 3Results posted
• Comparison of NN5401 Versus Insulin Glargine, Both Combined With Metformin Treatment, in Subjects With Type 2 DiabetesCompletedNCT01045707Phase 3Results posted
• Comparison of NN5401 With Insulin Glargine, Both in Combination With Oral Antidiabetic Drugs, in Subjects With Type 2 DiabetesCompletedNCT01045447Phase 3Results posted
• Comparison of NN5401 With Biphasic Insulin Aspart 30 in Type 2 DiabetesCompletedNCT01009580Phase 3Results posted
• Comparison of NN1250 With Insulin Glargine in Type 2 DiabetesCompletedNCT01006291Phase 3Results posted
• Comparison of NN1250 Versus Insulin Glargine in Subjects With Type 2 DiabetesCompletedNCT00982644Phase 3Results posted
• Comparison of NN5401 Plus Insulin Aspart With Insulin Detemir Plus Insulin Aspart in Type 1 DiabetesCompletedNCT00978627Phase 3Results posted
• Comparison of NN5401 Versus Biphasic Insulin Aspart 30 on a Twice Daily Regimen in Subjects With Type 2 Diabetes MellitusCompletedNCT00842361Phase 2Results posted
• Comparison of Two NN5401 Formulations Versus Biphasic Insulin Aspart 30, All in Combination With Metformin in Subjects With Type 2 DiabetesCompletedNCT00613951Phase 2Results posted
• Insulin Degludec vs Insulin Glargine for Glycemic Control in Critical Illness HyperglycemiaCompletedNCT06178874Not applicable
• INHALE-3: Afrezza® Combined With Insulin Degludec Versus Usual Care in Adults With Type 1 DiabetesCompletedNCT05904743Phase 4
• A Study of Insulin Degludec/Insulin Aspart Biosimilar (22011) Compared With Insulin Degludec/Insulin Aspart(Ryzodeg) in Participants With Type 2 Diabetes in ChinaCompletedNCT05802862Phase 3
• Risk of Hypoglycemia in the Transition From Inpatient to Outpatient Setting. Comparative Study of Basal-bolus Insulin Versus Basal Insulin Plus GLP-1 AnalogueStatus unknownNCT05767255Phase 3
• Effects of Degludec/Liraglutide on Time in Range, Inflammation and Endothelial Function vs Insulin Basal Bolus in Diabetic InpatientsCompletedNCT05360537Phase 4
• Degludec Glargine U300 Hospital StudyCompletedNCT05036876Not applicable
• Safety and Efficacy of Insulin Degludec/Insulin Aspart in Patients With T1DMStatus unknownNCT04965051Not applicable
• Insulin Glargine U300 vs Insulin Degludec U100 in Impact on the Glycaemic and Cardiovascular FactorsCompletedNCT04692415Phase 4
• Intermediate and Long Acting Insulin Young Children Type 1 Diabetes.Status unknownNCT04664764Phase 4
• Flexible Insulin Therapy Untethered Insulin Regimen in Avidly Exercising Patients With Type 1 Diabetes: FIT UntetheredStatus unknownNCT03838783Phase 4
• A Study of LY3374849 in Healthy ParticipantsCompletedNCT03726125Phase 1
• Reducing the Risk of Metabolic Decompensation in Diabetic Adolescents by Supervised School Administration of InsulinCompletedNCT03400501Early Phase 1
• Evaluation of Glycaemic Control Using GlucoTab® With Insulin Degludec in Hospitalized Patients With Diabetes Mellitus Type 2CompletedNCT03387787Phase 2/3
• Randomised Open Label Study of Insulin Degludec Versus Insulin Glargine U100 in RamadanTerminatedNCT03349840Phase 4
• Impact on the Oxidative Stress of the Different Analogues of Insulin in People With Type 1 Diabetes. (Ineox Study)CompletedNCT03328845Phase 4
• A Trial to Investigate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide Compared With Insulin Degludec and Liraglutide in Healthy Chinese SubjectsCompletedNCT03292185Phase 1
• Basal-bolus Insulin Therapy Versus Standard Therapy for the Inpatient Management of Type 2 Diabetes: the IDA2 StudyStatus unknownNCT03244241Phase 4
• Insulin Degludec for the Management of Patient With Recurrent Diabetic KetoacidosisTerminatedNCT03001323Not applicable
• A Trial Investigating the Pharmacokinetic Properties of Insulin Degludec/Insulin Aspart in Healthy Chinese SubjectsCompletedNCT02844790Phase 1
• Comparing Pharmacodynamic and Pharmacokinetic Properties of Insulin Degludec and Insulin Glargine 300 U/mL at Steady-state Conditions in Subjects With Type 1 Diabetes MellitusCompletedNCT02536859Phase 1
• Insulin Degludec and Symptomatic Nocturnal HypoglycaemiaCompletedNCT02192450Phase 4
• A Trial to Demonstrate Bioequivalence Between Two Insulin Degludec/Liraglutide Formulations, B5 and V2 in Healthy SubjectsCompletedNCT01916174Phase 1
• Bioequivalence Between Two Explorative Insulin Degludec Formulations and Between Two Explorative IDegAsp Formulations in Healthy SubjectsCompletedNCT01868581Phase 1
• Comparison of IDegAsp (Inclusive Three Explorative Formulations) With Insulin Degludec and Insulin Aspart Separately Injected in Subjects With Type 1 DiabetesCompletedNCT01868568Phase 1
• Safety, Pharmacokinetics and Pharmacodynamics of Two IDegAsp (One Explorative) Preparations and Two Insulin Degludec (One Explorative) Preparations in Japanese SubjectsCompletedNCT01868555Phase 1
• Comparison of Insulin Degludec With Insulin Glargine in Subjects With Type 1 Diabetes MellitusCompletedNCT01868529Phase 1
• Safety, Tolerability and Pharmacokinetic and Pharmacodynamic Characteristics of Explorative Formulations of Insulin Degludec and IDegAsp 50 in Healthy Japanese SubjectsCompletedNCT01865331Phase 1
• Investigation of Pharmacodynamic Characteristics of Explorative Formulation of Insulin Degludec in Male Subjects With Type 1 DiabetesCompletedNCT01865318Phase 1
• Comparison of Explorative Formulation of Insulin Degludec and Insulin Aspart Co-formulation Versus Explorative Formulation of Insulin Degludec and Insulin Aspart Separately Compared With Biphasic Insulin Aspart 30 in Male Subjects With DiabetesCompletedNCT01865305Phase 1
• Comparing the Pharmacodynamics and Pharmacokinetics of Explorative Formulation of Insulin Degludec With Insulin Glargine in Subjects With Type 1 and Type 2 DiabetesCompletedNCT01865292Phase 1
• A Trial Investigating the Pharmacodynamic and Pharmacokinetic Properties of Insulin Degludec/Insulin Aspart 15 in Subjects With Type 1 DiabetesCompletedNCT01773798Phase 1
• A Trial Comparing the Effect of Exercise on Blood Glucose in Subjects With Type 1 Diabetes, Who Are Treated With Either Insulin Degludec or Insulin GlargineCompletedNCT01704417Phase 1
• A Trial Investigating the Absolute Bioavailability of Insulin Degludec in Healthy SubjectsCompletedNCT01623375Phase 1
• A Trial Investigating the Pharmacodynamic Properties of NN5401 in Subjects With Type 1 DiabetesCompletedNCT01590836Phase 1
• A Trial Investigating the Effect of NN1250 in Japanese Subjects With Type 2 DiabetesTerminatedNCT01467414Phase 1

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