Incretins: all 1,182 studies that test it

Page 2 of 12. Open to participants first (46), then studies with results posted, then the rest; newest registration first within each.

• Interaction of Bexagliflozin With Metformin, Glimepiride and SitagliptinCompletedNCT02956044Phase 1Results posted
• Safety and Efficacy of Liraglutide in Parkinson's DiseaseCompletedNCT02953665Phase 2Results posted
• Treatment of Diabetes in Patients With Systolic Heart FailureCompletedNCT02920918Phase 4Results posted
• Effect of Liraglutide for Weight Management in Pubertal Adolescent Subjects With ObesityCompletedNCT02918279Phase 3Results posted
• Mechanistic Evaluation of Glucose-lowering Strategies in Patients With Heart FailureCompletedNCT02917031Phase 4Results posted
• A Double-blinded Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec Both in Combination With Metformin in Japanese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal or Pre-mix/Combination Insulin Therapy and Oral Anti-diabetic DrugsCompletedNCT02911948Phase 3Results posted
• Lifestyle Modification and LiraglutideCompletedNCT02911818Phase 4Results posted
• Linagliptin Add-on to Insulin Background TherapyCompletedNCT02897349Phase 3Results posted
• Study to Assess the Efficacy of Liraglutide in Patients With Type 2 Diabetes MellitusCompletedNCT02889510Phase 3Results posted
• Phase 3 Alogliptin Pediatric StudyCompletedNCT02856113Phase 3Results posted
• Empa/Lina FDC Food Effect Study (Japan)CompletedNCT02815644Phase 1Results posted
• An Exploratory Study on the Effects of Repeat Doses of Albiglutide Compared to Exenatide on Gastric Myoelectrical Activity and Gastric Emptying in Type 2 Diabetes Mellitus SubjectsTerminatedNCT02793154Phase 4Results posted
• A Study of the Safety and Efficacy of Sitagliptin Addition During Metformin Up-titration (MK-0431-848)CompletedNCT02791490Phase 3Results posted
• Effects of Single Doses of Liraglutide and Dapagliflozin on Ketogenesis in Type 1 DiabetesCompletedNCT02777073Not applicableResults posted
• A Clinical Trial Comparing Glycaemic Control and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Insulin Glargine (IGlar) as add-on Therapy to SGLT2i in Subjects With Type 2 Diabetes MellitusCompletedNCT02773368Phase 3Results posted
• An Exploratory Study of the Effects of Trelagliptin and Alogliptin on Glucose Variability in Patients With Type 2 Diabetes MellitusCompletedNCT02771093Phase 4Results posted
• The Effect of Liraglutide Treatment on Postprandial Chylomicron and VLDL Kinetics, Liver Fat and de Novo LipogenesisCompletedNCT02765399Phase 4Results posted
• Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Linagliptin Compared With the Free Combination of Empagliflozin Tablet and Linagliptin Tablet in Healthy Male and Female SubjectsCompletedNCT02758171Phase 1Results posted
• Sitagliptin in Non-Diabetic Patients Undergoing General SurgeryCompletedNCT02741687Phase 4Results posted
• Randomized Sitagliptin Withdrawal Study (MK-0431-845)CompletedNCT02738879Phase 3Results posted
• Efficacy in Controlling Glycaemia With Victoza® (Liraglutide) as add-on to Metformin vs. OADs as add-on to Metformin After up to 104 Weeks of Treatment in Subjects With Type 2 DiabetesCompletedNCT02730377Phase 4Results posted
• Sitagliptin for Prevention of Acute Graft Versus-Host Disease After Allogeneic Hematopoietic Stem Cell TransplantationCompletedNCT02683525Phase 2Results posted
• DPP4 Inhibition & Beta Cell FunctionCompletedNCT02683187Phase 1Results posted
• A Multi-Center, Randomized, Double-Blind, Phase III Trial to Evaluate the Safety and Efficacy of Saxagliptin Co-administered With Dapagliflozin Compared to Saxagliptin or Dapagliflozin All Given as add-on Therapy to Metformin in Subject With Type 2 DiabetesCompletedNCT02681094Phase 3Results posted
• Energy Balance & Weight Loss in Craniopharyngioma-related or Other Hypothalamic Tumors in Hypothalamic ObesityCompletedNCT02664441Phase 3Results posted
• Pilot Study of the Effect of Liraglutide on Weight Loss and Gastric Functions in ObesityCompletedNCT02647944Phase 2Results posted
• Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Sitagliptin (REMIT-Sita)CompletedNCT02623998Phase 3Results posted
• ESR-15-11293 - Saxa/Dapa, Safety and Efficacy StudyCompletedNCT02613897Not applicableResults posted
• Continuous Glucose Monitoring to Assess Glycemia in Chronic Kidney Disease - Changing Glucose ManagementCompletedNCT02608177Not applicableResults posted
• A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Japanese Subjects With Type 2 Diabetes Mellitus.CompletedNCT02607306Phase 3Results posted
• Double-blind Sitagliptin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Ipragliflozin (MK-0431J-842)CompletedNCT02577016Phase 3Results posted
• Ipragliflozin Add-on Long-term Study in Japanese Participants With Type 2 Diabetes Mellitus on Sitagliptin (MK-0431J-849)CompletedNCT02564211Phase 3Results posted
• Sitagliptin for Hyperglycemia in Patients With T2DM Undergoing Cardiac SurgeryCompletedNCT02556918Phase 4Results posted
• A Study to Evaluate the Effect of Dapagliflozin With and Without Saxagliptin on Albuminuria, and to Investigate the Effect of Dapagliflozin and Saxagliptin on HbA1c in Patients With Type 2 Diabetes and CKDCompletedNCT02547935Phase 2/3Results posted
• Sitagliptin Therapy and Kinetics of Inflammatory MarkersCompletedNCT02536248Phase 3Results posted
• A 12/24-weeks, Open, Multi-centre, Phase IV Study on Safety and Efficacy of 2mg Exenatide Once Weekly (Bydureon) in T2DM Patients.CompletedNCT02533453Phase 4Results posted
• A Study to Assess the Addition of Sitagliptin to Metformin Compared With the Addition of Dapagliflozin to Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) and Mild Renal Impairment Who Have Inadequate Glycemic Control on Metformin With or Without a Sulfonylurea (MK-0431-838)CompletedNCT02532855Phase 3Results posted
• Effect of Liraglutide for Weight Management in Paediatric Subjects With Prader-Willi SyndromeCompletedNCT02527200Phase 3Results posted
• Liraglutide in Adolescents With Type 1 DiabetesCompletedNCT02516657Phase 3Results posted
• Sitagliptin for Reducing Inflammation and Immune ActivationCompletedNCT02513771Phase 2Results posted
• A Trial Comparing the Efficacy and Safety of Liraglutide 1.8 mg/Day to Liraglutide 0.9 mg/Day in Japanese Subjects With Type 2 Diabetes Mellitus.CompletedNCT02505334Phase 3Results posted
• A 104 Week Clinical Trial Comparing Long Term Glycaemic Control of Insulin Degludec/Liraglutide (IDegLira) Versus Insulin Glargine Therapy in Subjects With Type 2 Diabetes MellitusCompletedNCT02501161Phase 3Results posted
• Efficacy and Safety of Dapagliflozin and Dapagliflozin Plus Saxagliptin in Combination With Metformin in Type 2 Diabetes Patients Compared With SulphonylureaCompletedNCT02471404Phase 4Results posted
• Linagliptin's Effect on CD34+ Stem CellsCompletedNCT02467478Phase 4Results posted
• Exenatide Inpatient Trial: A Randomized Controlled Pilot Trial on the Safety and Efficacy of Exenatide (Byetta®) Therapy for the Inpatient Management of Patients With Type 2 DiabetesCompletedNCT02455076Phase 4Results posted
• Sitagliptin in Non-Diabetic Patients Undergoing Cardiac SurgeryCompletedNCT02443402Phase 4Results posted
• A Clinical Proof-of-principle Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of NNC0114-0006 and Liraglutide on Preservation of Beta-cell FunctionCompletedNCT02443155Phase 2Results posted
• A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes MellitusCompletedNCT02420262Phase 3Results posted
• A 52-week International, Multicenter Trial With a Long -Term Extension to Evaluate Saxagliptin With Dapagliflozin in Combination With Metformin Compared to Glimepiride in Combination With Metformin in Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin AloneCompletedNCT02419612Phase 3Results posted
• Exenatide Weekly Injections as an Adjunctive Treatment in Patients With SchizophreniaCompletedNCT02417142Phase 4Results posted
• The INDORSE Study: Inhibition of Dipeptidyl Peptidase IV: Outcomes on Renal Sodium ExcretionCompletedNCT02406443Phase 4Results posted
• Risk of Nocturnal Hypoglycemia and Arrhythmias With Sitagliptin Versus Glimepiride in Patients With Type 2 DiabetesTerminatedNCT02373865Phase 4Results posted
• The Effect of LINAGLIPTIN on Inflammation, Oxidative Stress and Insulin Resistance in Obese Type 2 Diabetes SubjectsCompletedNCT02372630Phase 4Results posted
• Effects of Linagliptin on Endothelial FunctionCompletedNCT02350478Phase 4Results posted
• Randomized Trial Comparing Sitagliptin to Placebo in Closed LoopCompletedNCT02328040Phase 1Results posted
• Effect of Combined Incretin-Based Therapy Plus Canagliflozin on Glycemic Control and the Compensatory Rise in Hepatic Glucose Production in Type 2 Diabetic PatientsCompletedNCT02324842Not applicableResults posted
• Efficacy of Sitagliptin and Glibenclamide on the Glucose Variability in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431-355)CompletedNCT02318693Phase 4Results posted
• Dietary Impacts on Glucose-lowering Effects of Sitagliptin in Type 2 DiabetesCompletedNCT02312063Phase 4Results posted
• A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) in Subjects With Type 2 Diabetes Mellitus Using Two Different Titration AlgorithmsCompletedNCT02298192Phase 3Results posted
• Study to Evaluate the Effect of BYDUREON on 24-hour Glucose Control in Metformin Treated Patients With Type 2 Diabetes.CompletedNCT02288273Phase 4Results posted
• Study to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin in Combination With Metformin Compared to Sitagliptin in Combination With Metformin in Adult Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Therapy AloneCompletedNCT02284893Phase 3Results posted
• Effect of Food on the Pharmacokinetics of Single Oral Dose Administration of a Fixed-Dose Combination of SYR-322 and Metformin Hydrochloride in Healthy Adult Male SubjectsCompletedNCT02276274Phase 3Results posted
• Evaluate the Efficacy and Safety of Saxagliptin in Combination With Metformin IR Compared to Saxagliptin Monotherapy and to Metformin IR Monotherapy in Drug Naive Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic ControlCompletedNCT02273050Phase 3Results posted
• Sitagliptin and Glucagon CounterregulationCompletedNCT02256189Phase 4Results posted
• Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal SyndromeCompletedNCT02251431Phase 3Results posted
• 24-Week, Multicenter, Randomized, Parallel-group, Open-label, Active Controlled Phase IV Study to Assess the Efficacy, Safety and Tolerability of Saxagliptin Compared With Acarbose When in Combination With Metformin in Patients With T2D Inadequately Controlled With Metformin MonotherapyCompletedNCT02243176Phase 4Results posted
• Linagliptin as Add on to Basal Insulin in the ElderlyCompletedNCT02240680Phase 4Results posted
• Phase III Study to Evaluate Safety and Efficacy of Added Exenatide Versus Placebo to Titrated Basal Insulin Glargine in Inadequately Controlled Patients With Type II Diabetes MellitusCompletedNCT02229383Phase 3Results posted
• Efficacy and Safety of Ertugliflozin (MK-8835/PF-04971729) With Sitagliptin in the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Diet and Exercise (MK-8835-017)CompletedNCT02226003Phase 3Results posted
• Bioequivalence Study Coadministered to Healthy Subjects in the Fasted StateCompletedNCT02223065Phase 1Results posted
• Safety and Efficacy of Saxagliptin for Glycemic Control in Non-Critically Ill Hospitalized PatientCompletedNCT02182895Phase 4Results posted
• Effect of Exenatide in Obese Patients With Accelerated Gastric EmptyingCompletedNCT02160990Phase 4Results posted
• Liver and Fat Regulation in Overweight Adolescent GirlsCompletedNCT02157974Phase 2/3Results posted
• Effect of Chronic ACE and DPP4 Inhibition on Blood PressureCompletedNCT02130687Not applicableResults posted
• The Effect of Dipeptidyl Peptidase 4 Inhibition on Growth Hormone Secretion in Women With Polycystic Ovarian SyndromeCompletedNCT02122380Phase 4Results posted
• Bioequivalence of a FDC Tablet of Linagliptin/Metformin (2.5mg/750mg) Extended Release in Healthy SubjectsCompletedNCT02121509Phase 1Results posted
• A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 DiabetesCompletedNCT02119819Phase 2Results posted
• Evaluate the Efficacy and Safety of Saxagliptin Added to Insulin Monotherapy or to Insulin Combined With Metformin in Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic ControlCompletedNCT02104804Phase 3Results posted
• Effects of Antidiabetic Medications on the Postprandial State in PrediabetesCompletedNCT02104739Phase 4Results posted
• Ertugliflozin and Sitagliptin Co-administration Factorial Study (VERTIS FACTORAL, MK-8835-005)CompletedNCT02099110Phase 3Results posted
• The Efficacy and Safety of Liraglutide Adjunct to Insulin Treatment in Type 1 DiabetesCompletedNCT02098395Phase 3Results posted
• Bioequivalence of a FDC Tablet of Linagliptin/Metformin (5mg/1000mg) Extended Release in Healthy SubjectsCompletedNCT02084082Phase 1Results posted
• Bioequivalence of a FDC Tablet of Linagliptin/Metformin (2.5mg/1000mg) Extended Release in Healthy Subjects.CompletedNCT02084056Phase 1Results posted
• A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM)TerminatedNCT02072096Phase 4Results posted
• ADA Linagliptin in Long Term CareCompletedNCT02061969Phase 4Results posted
• Intravenous Exenatide in Patients With Acute Brain InjuryCompletedNCT02058940Phase 4Results posted
• Use of Sitagliptin to Decrease MicroalbuminuriaTerminatedNCT02048904Phase 4Results posted
• Effect of Saxagliptin on EPCs as a Cellular Biomarker for Evaluating Endothelial Dysfunction in Early T2DM PatientsCompletedNCT02024477Phase 4Results posted
• A Study of the Safety and Effectiveness of LY3053102 in Participants With Type 2 DiabetesTerminatedNCT02020616Phase 1/2Results posted
• Januvia (Sitagliptin) in Healing Chronic Diabetic Foot UlcersTerminatedNCT02015910Phase 4Results posted
• Effect of Liraglutide on Epicardial Fat in Subjects With Type 2 DiabetesCompletedNCT02014740Phase 4Results posted
• The Efficacy and Safety of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin in Chinese Subjects With Type 2 DiabetesCompletedNCT02008682Phase 4Results posted
• Linagliptin Inpatient TrialCompletedNCT02004366Phase 4Results posted
• Efficacy and Safety of Liraglutide Versus Lixisenatide as add-on to Metformin in Subjects With Type 2 DiabetesCompletedNCT01973231Phase 4Results posted
• Use of Sitagliptin for Stress Hyperglycemia or Mild Diabetes Following Cardiac SurgeryTerminatedNCT01970462Phase 4Results posted
• The Effect of Linagliptin on Mitochondrial and Endothelial FunctionCompletedNCT01969084Phase 4Results posted
• The Effect of Simple Basal Insulin Titration, Metformin Plus Liraglutide for Type 2 Diabetes With Very Elevated HbA1c - The SIMPLE StudyCompletedNCT01966978Phase 4Results posted
• Sitagliptin Versus Placebo in the Treatment of Non-alcoholic Fatty Liver DiseaseCompletedNCT01963845Phase 2Results posted
• A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide Versus Insulin Glargine in Subjects With Type 2 Diabetes MellitusCompletedNCT01952145Phase 3Results posted
• Effect of Exenatide on Liver and Heart Fat and InflammationCompletedNCT01951651Phase 4Results posted

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