Hypnotics and Sedatives: all 2,749 studies that test it

Page 15 of 28. Open to participants first (425), then studies with results posted, then the rest; newest registration first within each.

• Comparison of TIVA by Closed Loop Anaesthesia Delivery System Versus Target Controlled Infusion DeviceCompletedNCT04731480Not applicable
• Dexmedetomidine for Intraoperative Shivering in Scheduled Elective Cesarean DeliveryWithdrawnNCT04730609Phase 4
• Cognitive Dysfunction After Cataract SurgeryCompletedNCT04730596Not applicable
• Evaluation of the Effect of Different Doses Dexmedetomidine Infusion on Lung Mechanics and Oxygenation in Obese PatientsCompletedNCT04730375Phase 2
• Effects of Dexmedetomidine vs Propofol in Patients With Intra-abdominal SepsisCompletedNCT04718714Phase 4
• The Use of Midazolam as Adjuvant to Bupivacaine Intrathecal Anesthesia for Children Undergoing Lower Abdominal Surgeries.CompletedNCT04718259Early Phase 1
• Role of Alprazolam in the Management of Acute Coronary SyndromeStatus unknownNCT04715269Phase 1/2
• Opioid Sparing Anaesthesia for Prevention of Postoperative Nausea and Vomiting in Laparoscopic Gynecological SurgeryCompletedNCT04706897Phase 4
• Effect of Co-administration Lidocaine and Dexmedetomidine on Quality of RecoveryCompletedNCT04706767Not applicable
• Comparison Between Dexmeditomidine, Midazolam and Ketamine as a Sedative to Help Cannula Insertion in Pediatric PatientCompletedNCT04704622Phase 2/3
• Effect of Anesthetic Drugs on Neurocognitive Function in Children With Retinoblastoma Requiring Multiple Anesthetic Exposure - Preliminary StudyStatus unknownNCT04700514Not applicable
• Comparison of Doses of Dexmedetomidine With Bupivacaine in Caudal Block for Duration of Analgesia in Paediatric Infraumblical Surgeries.Status unknownNCT04700228Phase 4
• Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine (Second Sub-Project)CompletedNCT04700007Not applicable
• Dexamethasone and Dexmedetomidine as an Adjuvant to Spinal Anesthesia for Elective Caesarean SectionsStatus unknownNCT04697745Not applicable
• Ultrasound-guided Regional Anesthesia vs Local Infiltration Anesthesia With Dexmedetomidine and RopivacaineCompletedNCT04697537Phase 3
• A Study to Evaluate Next Day Effects of TS-142 on Driving Performance in Healthy SubjectsCompletedNCT04696952Phase 1
• Peri-neural Dexmedetomidine Versus Dexamethasone for Supraaclavicular Block Adjuvant to Bupivacaine Supraclavicular Brachial Plexus BlockCompletedNCT04694105Not applicable
• Sedation Techniques for Outpatient ColonoscopyCompletedNCT04686058Phase 3
• Study of Midazolam in Healthy AdultsCompletedNCT04679623Phase 1
• Dexmedetomidine Compared to Ketofol for Sedation in PaediatricsCompletedNCT04678050Phase 1
• The DDI Study Had Been Designed to Investigate the Effect of SHR3680 on the Pharmacokinetics of Midazolam, S-Warfarin and OmeprazoleCompletedNCT04676035Phase 1
• Dexmedetomidine Facilitate AnalgesiaCompletedNCT04675372Phase 4
• Dexmedetomidine Alleviates Postoperative Delirium After Brain Tumor ResectionsCompletedNCT04674241Not applicable
• Lorazepam Effects on Neuroimaging MeasuresWithdrawnNCT04671836Early Phase 1
• Subtenon and Intravenous Dexmedetomidine Effect on Patients Undergoing Cataract SurgeryStatus unknownNCT04668456Phase 3
• Dexmedetomidine and Melatonin for Sleep Induction for EEG in ChildrenCompletedNCT04665453Not applicable
• Requirements of Propofol With Target Controlled Infusions for Supraglottic Airway DevicesCompletedNCT04664595Not applicable
• Co-administration of Dexmedetomidine in Carotid Endarterectomy (CEA)CompletedNCT04662177Phase 4
• Dexmedetomidine Adjuvant Treatment for Depressed Patients Undergoing ECTStatus unknownNCT04661475Phase 4
• Attenuation of Airway and Cardiovascular Responses to Extubation in Chronic SmokersStatus unknownNCT04659642Early Phase 1
• Nebulized Lidocaine, Dexmedetomedine and Their Combination in Direct Laryngoscopy SurgeryCompletedNCT04659057Phase 4
• Intranasal Dexmedetomidine Versus Intranasal Midazolam for MRI In PediatricsCompletedNCT04652661Phase 4
• Application of Dexmedetomidine Hydrochloride Injection in Anesthesia for Patients Without Tracheal IntubationStatus unknownNCT04652427Not applicable
• Hemodynamic Stability of Dexmedetomidine in Hypertensive Patients Undergoing Laparoscopic CholecystectomyStatus unknownNCT04646317Early Phase 1
• Lorazepam for the Analgosedation of Pediatric Patients in Mechanical Ventilation.Status unknownNCT04646135Phase 2
• Dexmedetomidine as an Adjuvant for Femoral Nerve Block and Functional Recovery After Total Knee ArthroplastyCompletedNCT04642651Phase 4
• DexmedetOmidine Complement Treats Chronic insOmnia and Improves Circadian Rhythm (DOCTOR)CompletedNCT04635098Not applicable
• Comparison of the Perioperative Effects of Dexmedetomidine and Ketamine Sedation in Septorhinoplasty OperationsCompletedNCT04628559Not applicable
• Intranasal Versus Intravenous Drug in Painful Procedure for Outpatient Oncologic ParticipantsStatus unknownNCT04621110Phase 3
• Propofol Versus Sevoflurane During FESSStatus unknownNCT04619160Phase 4
• Intrathecal Versus Intravenous Dexmeditomedine in Transurethral Resection of the ProstateStatus unknownNCT04618965Phase 4
• Buccal Versus Intranasal Route of Administration of Midazolam Spray in Behavior Management of Pre-School PatientsCompletedNCT04608734Phase 2
• Dexmedetomidine Supplemented Analgesia in Patients at High-risk of Obstructive Sleep ApneaCompletedNCT04608331Phase 4
• Dexmedetomidine Infusion Effect on Hemodynamic Variables During CraniotomyCompletedNCT04607525Phase 4
• Effects of TIVA Versus Inhalational Anaesthesia on Circulating Tumour Cells in Hepatocellular Carcinoma PatientsStatus unknownNCT04601961Not applicable
• Dexmedetomidine Versus Ketamine Versus Midazolam in Endoscopic ProceduresCompletedNCT04597268Not applicable
• A Double-blind, Placebo-controlled Study of Antidepressant Augmentation With AgomelatineCompletedNCT04589143Phase 4
• Effects of Dexmedetomidine on Cardiac Electrophysiology in Patients Under General Anesthesia During Perioperative PeriodCompletedNCT04577430Not applicable
• Ketamine Infusion vs Dexmedetomidine Infusion in Obese Patients Undergoing Bariatric SurgeryStatus unknownNCT04576975Phase 3
• Nebulized Lidocaine and Intranasal Midazolam for NGT Insertion in ChildrenStatus unknownNCT04571879Phase 3
• NOL Index to Compare the Intraoperative Analgesic Effect of Propofol Versus SevofluraneCompletedNCT04567160Phase 4
• Study of Edasalonexent With Midazolam and Deflazacort in Healthy SubjectsCompletedNCT04543370Phase 1
• VR Sedation in Third Molar SurgeryActive, not recruitingNCT04540666Not applicable
• Unilateral Transversus Abdominis Plane Block in PediatricsCompletedNCT04539314Not applicable
• Opioid Sparing Analgesia: Dexmedetomidine Versus Lidocaine for Intracranial Surgeries in ChildrenCompletedNCT04535089Phase 1/2
• Magnesium Sulphate, Dexemeditomedine and Emergency AgitationStatus unknownNCT04531371Phase 1
• Effect of Midazolam and Dexmedetomidine on Heart Function - A Randomized MRI-based Study.CompletedNCT04529187Phase 4
• The Effect of Dexmedetomidine During Opioid Free Anesthesia on Postoperative Recovery After GastrectomyCompletedNCT04529135Not applicable
• Midazolam Versus Dexamethasone as an Adjuvant to Local Anesthetics in the Ultrasound Guided Hydrodissection of Median Nerve for Treatment of Carpal Tunnel Syndrome PatientsCompletedNCT04527770Not applicable
• Evaluating Stress Response and Anxiety Score in Paediatric PatientsCompletedNCT04526652Phase 2
• Intraperitoneal Dexmedetomidine Versus Ketamine With Bupivacaine For Postoperative AnalgesiaCompletedNCT04525274Not applicable
• Effect of Transversus Abdominis Plane Block Combined With Dexmedetomidine Infusion on the Prognosis in Elderly Patients Undergoing Abdominal SurgeryStatus unknownNCT04516174Not applicable
• Intranasal Dexmedetomidine for Deep-sedated Pediatric Dental PatientsCompletedNCT04509414Phase 4
• Towards a Post-exposition Pharmacological Prophylaxis for Post-traumatic Stress DisorderCompletedNCT04508166Not applicable
• Anesthesia and Cancer Study: Renal Cell CarcinomaActive, not recruitingNCT04503148Not applicable
• Magnesium Sulfate in Combination With Dexmedetomidine As Adjuvants to LevobupivacaineCompletedNCT04498351Early Phase 1
• Impact Dexmedetomidine on Postoperative Delirium in Patients After Intracranial Operation for Brain TumorCompletedNCT04494828Phase 4
• Neuroprotection During Open Heart SurgeryCompletedNCT04486690Phase 3
• Phase 1 Bioavailability Study of MELT-100 (Midazolam and Ketamine Sublingual) and IV Midazolam or KetamineCompletedNCT04485702Phase 1
• Propofol Versus Sevoflurane Anesthesia in Pediatric Strabismus Surgery: Feasibility of BIS MonitoringCompletedNCT04485117Not applicable
• Dexmedetomidine Neuroprotection in Pediatric Cardiac SurgeryStatus unknownNCT04484922Not applicable
• Anesthesia and Acute Kidney Injury After NephrectomyCompletedNCT04474600Not applicable
• Pupillary Response to Incremental Tetanic Stimulations Under Propofol-remifentanil TCICompletedNCT04465773Not applicable
• f Adding Ketamine to Propofol For Drug-induced Sleep Endoscopy in Adult Patients With Obstructive Sleep ApneaCompletedNCT04452383Phase 4
• A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants With Major Depressive DisorderCompletedNCT04451187Phase 1
• Efficacy of Dexmedetomidine Versus Morphine as an Adjunct to Bupivacaine in Caudal Anesthesia.CompletedNCT04445636Not applicable
• Different Anesthesia Maintain Protocol Effect the Outcome of the PatientsCompletedNCT04443946Phase 4
• Analgesia After Knee Arthroscopy :Dexmedetomidine vs FentanylCompletedNCT04442906Not applicable
• Dexmedetomidine Versus Sevoflurane in Children With Anticipated Difficult IntubationStatus unknownNCT04426552Phase 2
• Comparison of Optic Nerve Sheath Diameter in Children Receiving Caudal Block According to Anesthetic Agents: Total Intravenous Anesthesia vs. Volatile AnesthesiaCompletedNCT04415905Not applicable
• Caudal Epidural With Non Opioid Adjuvants in Lumbosacral Spine SurgeryCompletedNCT04411329Not applicable
• Comparison Between Two Types of Sedation for Elective Upper Endoscopy ProceduresCompletedNCT04410211Not applicable
• the Effect of Opioid-free General AnesthesiaCompletedNCT04409964Not applicable
• Dexmedetomidine for Prevention of Postoperative Delirium After Intracranial Operation for Brain TumorStatus unknownNCT04399343Phase 4
• The Effect of Dexmedetomidine for Suprascapular Nerve Block With Axillary Nerve BlockCompletedNCT04398589Phase 4
• Dexmedetomidine or Fentanyl as Additives to Epidural Levobupivacaine in Painless LaborCompletedNCT04397406Phase 4
• Extension of Analgesia by Combined Injection of Dexamethasone and Dexmedetomidine After Arthroscopic Shoulder SurgeryCompletedNCT04394481Phase 4
• Wound Infiltration With Tramadol, Dexmedetomidine, or Magnesium Plus Ropivacaine for Pain Relief After Spine SurgeryCompletedNCT04391855Phase 4
• The Safety and Effectiveness of Cholinergic Receptor Block Therapy in the Treatment of ALSStatus unknownNCT04391361Phase 2
• Effect of Intratracheal Dexmedetomidine Administration on Recovery From General Anesthesia in Pediatrics Undergoing Lower Abdominal Surgery:CompletedNCT04385602Phase 2/3
• A Trial of Dexmedetomidine Hydrochloride Nasal Spray in Preoperative Sedation of AdultsCompletedNCT04383418Phase 3
• Dexmedetomidine Sublingual Film for the Management of Agitation in Delirium: Safety and Preliminary EfficacyWithdrawnNCT04382170Phase 2
• Comparison Between Intrathecal and Intravenous DexmedetomidineCompletedNCT04374318Not applicable
• Effect of Etomidate and Propofol on ElectroencephalographyStatus unknownNCT04369014Not applicable
• Association Between Anesthetic Drugs for General Anesthesia and Postoperative Intelligence/behavioral Assessment Results in ChildrenActive, not recruitingNCT04364945Not applicable
• Intravenous Dexmedetomidine in Cesarean Section Under Spinal AnesthesiaCompletedNCT04358367Phase 3
• Use of Dexmedetomidine in Light to Moderate Sedation in the Patient in the Palliative Situation of a Sars-cov-2 / COVID-19 InfectionWithdrawnNCT04350086Phase 4
• Effects of Dexmedetomidine on Microcirculation and Residual Kidney Function in Kidney DonorsStatus unknownNCT04346290Phase 4
• Dose-response Curves Between Propofol and Intraoperative Electroencephalographic PatternsCompletedNCT04345926Phase 4
• The Effect of Propofol on Dexamethasone-induced Perineal PruritusCompletedNCT04337073Early Phase 1

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