Histamine H2 Antagonists: all 99 studies that test it

Page 1 of 1. Open to participants first (6), then studies with results posted, then the rest; newest registration first within each.

• Paracetamol and Ibuprofen With or Without Famotidine for Calcific Tendinitis of the ShoulderNot yet recruitingNCT07539961Not applicable
• A Study to Prevent Infantile Spasms RelapseRecruitingNCT06819670Phase 2
• Novel Strategies for Reducing Burn Scar ItchRecruitingNCT06801626Phase 3
• Famotidine and Antacids for Treatment of DyspepsiaRecruitingNCT06241183Phase 4
• Drug Excretion in Breast MilkRecruitingNCT06056583Phase 4
• Gastrointestinal Dysmotility on Aspiration RiskRecruitingNCT05455359Phase 4
• Treatment of Long CoronaVirus Disease (COVID) (TLC) Feasibility TrialTerminatedNCT05946551Phase 3Results posted
• Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 PatientsTerminatedNCT05077969Phase 2Results posted
• Effect of Oral Cimetidine in the ProtoporphyriasCompletedNCT05020184Phase 2Results posted
• PROUD Study - Preventing Opioid Use DisordersTerminatedNCT04766996Phase 4Results posted
• Famotidine vs Placebo for the Treatment of Non-Hospitalized Adults With COVID-19CompletedNCT04724720Phase 2Results posted
• Clinical Study to Investigate the Urinary Excretion of N-nitrosodimethylamine (NDMA) After Ranitidine AdministrationCompletedNCT04397445Phase 1Results posted
• Antihistamines in Eosinophilic EsophagitisTerminatedNCT04248712Phase 2Results posted
• Repurposing a Histamine Antagonist to Benefit Patients With Pulmonary HypertensionCompletedNCT03554291Phase 2Results posted
• A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Disease Activity on Prior DMTTerminatedNCT03368664Phase 3Results posted
• This Study Tests the Effect of Certain Medicines on the Transport of Other Medicines in the Body of Healthy MenCompletedNCT03307252Phase 1Results posted
• Safety and Efficacy of Isatuximab in Lymphoblastic LeukemiaTerminatedNCT02999633Phase 2Results posted
• Histamine Glutamate Antagonism in StrokeCompletedNCT02142712Phase 2Results posted
• Open-label Safety and Pharmacokinetic Study of DUEXIS® (Ibuprofen and Famotidine) Tablets in Juvenile Idiopathic ArthritisCompletedNCT01563185Phase 4Results posted
• A Multi-center, Randomized, Double-blind Phase III Clinical Trial to Assess and Compare to the Efficacy and Safety of Lafutidine, Famotidine and Omeprazole-referenced in Korean Erosive Esophagitis PatientsCompletedNCT01499368Phase 3Results posted
• Cimetidine BiowaiversCompletedNCT01256879Phase 4Results posted
• Bronchial Hyper-responsiveness in Reflux CoughTerminatedNCT00668317Phase 3Results posted
• Extending Acute Stroke Trials to the Aerial Inter-hospital Transfer SettingCompletedNCT00585351Not applicableResults posted
• Ulcer Prevention Study in Post Gastric Bypass PatientsCompletedNCT00557349Phase 4Results posted
• Effect of Ranitidine on Hyper-IgE Recurrent Infection (Job's) SyndromeTerminatedNCT00527878Phase 2Results posted
• Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) TreatmentCompletedNCT00450216Phase 3Results posted
• Efficacy and Safety Study of Esomeprazole 20mg qd vs Ranitidine 150mg Bid in Patients With an NSAID-induced Gastric UlcerCompletedNCT00401752Phase 3Results posted
• Safety and Efficacy Study of Axid Use in Infants Suffering From Gastroesophageal Reflux Disease (GERD)CompletedNCT00373334Phase 3Results posted
• Evaluate the Effects of Famotidine or Rabeprazole on the PK of NirogacestatCompletedNCT07171619Phase 1
• Novel Preventive Approach Against Filgrastim-Induced Bone Pain in Cancer PatientsCompletedNCT06265077Phase 1/2
• Multimodal Pain Package vs. Regular Formulation for Pain Management in Ambulatory Spinal SurgeryWithdrawnNCT05965492Phase 3
• Leidos-Enabled Adaptive Protocol for Clinical Trials (LEAP-CT) in Hospitalized Patients With COVID-19 (Addendum 1)WithdrawnNCT05085574Phase 2
• Interest of Famotidine in Children With Sickle Cell DiseaseCompletedNCT05084521Phase 2/3
• LEAP-CT for Treatment of COVID-19 Patients (Master Protocol)CompletedNCT05077332Phase 2
• Cetirizine and Famotidine for COVID-19WithdrawnNCT04836806Phase 4
• An Outpatient Study Investigating Non-prescription Treatments for COVID-19TerminatedNCT04621149Phase 2
• Remotely-conducted Trial of Famotidine vs Placebo for Patients at Home With Coronavirus (COVID) of 2019 (COVID-19)WithdrawnNCT04565392Phase 4
• Role of Famotidine in the Clinical Improvement of COVID-19 Patients.CompletedNCT04504240Phase 3
• I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill PatientsActive, not recruitingNCT04488081Phase 2
• Histamine H1/H2 Receptors and Training AdaptationsCompletedNCT04450134Not applicable
• A Study in Healthy Male Subjects to Investigate the Effect of Famotidine and Efavirenz on the Way the Body Takes up, Distributes, and Gets Rid of Daridorexant.CompletedNCT04390334Phase 1
• The Efficacy of Cimetidin for Acute - Extrinsic Atopic Dermatitis Treated With Standard TherapyStatus unknownNCT04018131Phase 3
• Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart DiseaseCompletedNCT03667703Phase 4
• Effect of Cimetidine on the PK of ImegliminCompletedNCT03618316Phase 1
• Effect of Anti-histamine in Prevention Systolic Hypotension After ProtamineCompletedNCT03583567Phase 4
• Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Contraceptive, Famotidine, or Fluconazole in Healthy SubjectsCompletedNCT03451110Phase 1
• Study of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive CytologyCompletedNCT03330028Phase 1
• A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy SubjectsCompletedNCT03302845Phase 1
• Histamine Receptor 2 Antagonists as Enhancers of Anti-Tumour ImmunityCompletedNCT03145012Phase 4
• A Study to Examine the Effect of Omeprazole, Famotidine, and an Acidic Beverage on the Pharmacokinetics of Entinostat in Healthy Adult SubjectsCompletedNCT02922933Phase 1
• Does Pantoprazole Reduce the Anti-platelet Effect of Clopidogrel?CompletedNCT02733640Not applicable
• Pharmacokinetic Properties and Effect of Food on Pharmacokinetic Properties of the Oral Lafutidine TabletsCompletedNCT02658864Phase 1
• The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult VolunteersCompletedNCT02581696Phase 1
• Anesthetics in Rhytidoplasty - A Comparison StudyCompletedNCT02410460Not applicable
• Modulation of Heme Oxygenase 1 by Nizatidine and Lisinopril in Healthy SubjectsCompletedNCT02232308Phase 1
• A Comparison of Efficacy of Intravenous Esomeprazole and Ranitidine Treatment of Dyspeptic PainCompletedNCT02197143Phase 4
• Tiotropium in Combination With Concomitant Cimetidine or Ranitidine in Healthy Male and Female SubjectsCompletedNCT02172417Phase 1
• The Study of Eustachian Tube Dysfunction and Laryngopharyngeal RefluxWithdrawnNCT02123498Phase 4
• Study Of Three Different Stomach Acid Reducing Agents When Given With Palbociclib (PD-0332991) And FoodCompletedNCT02097329Phase 1
• Famotidine in SchizophreniaStatus unknownNCT01946295Phase 2/3
• Famotidine for Levodopa-induced Dyskinesia in PDCompletedNCT01937078Phase 2
• Placebo Controlled Phase IV Study to Compare the Efficacy and Safety of a Single Dose of Oral Talcid, a Single Dose of Oral Famotidine and a Single Dose of Placebo in Patients With Acute Heartburn EpisodesCompletedNCT01928888Phase 4
• Lesinurad Interaction Study With RanitidineCompletedNCT01908257Phase 1
• Assess Pharmacokinetics of Fostamatinib in Fed and Fasted State in Combination With Ranitidine to Assess BioavailabilityCompletedNCT01682408Phase 1
• Study in Healthy Volunteers to Assess Effect of Omeprazole and Ranitidine on the Pharmacokinetics of VandetanibCompletedNCT01539655Phase 1
• Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed StatesCompletedNCT01538797Phase 1
• Dexpramipexole and Cimetidine Drug Drug Interaction (DDI)CompletedNCT01536249Phase 1
• Bioavailability Study of Famotidine Tablets 40 mg Under Fasting ConditionsCompletedNCT01511731Phase 1
• ASP (PPI_H2RA) Study-H2RA Versus PPI for the Prevention of Recurrent UGIB in High-risk Users of Low-dose ASACompletedNCT01408186Phase 3
• Mechanisms of N-acetylcysteine Mediated Vascular Adverse EffectsCompletedNCT01209455Not applicable
• PPI vs H2RA in Patients With Helicobacter Pylori-Negative Idiopathic Bleeding UlcersCompletedNCT01180179Phase 4
• Bioequivalence Study of Nizatidine Capsules 300 mg of Dr.Reddy's Laboratories Limited Under Fasting ConditionsCompletedNCT01161940Phase 1
• Bioequivalence Study of Nizatidine Capsules 300 mg of Dr.Reddy's Laboratories Limited Under Non- Fasting ConditionsCompletedNCT01161927Phase 1
• Bioequivalency Study of Ranitidine Tablets 300 mg of Dr. Reddy's Under Fasting ConditionsCompletedNCT01131702Phase 1
• A Relative Bioavailability Study of 20 mg Famotidine Tablets Under Fasting ConditionCompletedNCT01079065Not applicable
• A Relative Bioavailability Study of 20 mg Famotidine Tablets Under Fed ConditionCompletedNCT01079052Not applicable
• Influence of Esomeprazole on Antiplatelet Action of Clopidogrel Associated With AspirinCompletedNCT01062516Phase 4
• Class 3 BiowaiversCompletedNCT01010698Phase 1
• Esomeprazole or Famotidine in the Management of Aspirin Related Non-Ulcer DyspepsiaStatus unknownNCT00978159Phase 4
• Platelet Inhibitory Effect of Clopidogrel in Patients Treated With Omeprazole, Pantoprazole, or FamotidineCompletedNCT00950339Phase 4
• Comparison of Intravenous Pantoprazole and Famotidine for Stress Ulcer ProphylaxisTerminatedNCT00839488Phase 4
• A Clinico-Bacteriological Study and Effect of Stress Ulcer Prophylaxis on Occurrence of Ventilator Associated PneumoniaCompletedNCT00702871Phase 4
• Prevention of Gastrointestinal Bleeding in Patients With Severe Ischemic Heart DiseaseCompletedNCT00683111Phase 4
• Comparison of Esomeprazole and Famotidine for Stress Ulcer Prophylaxis in Neurosurgical Intensive Care UnitCompletedNCT00633035Phase 4
• Gastric pH in Critically Ill PatientsCompletedNCT00590928Phase 4
• Histamine H2 Antagonism as Adjuvant Therapy in Treatment Resistant SchizophreniaCompletedNCT00565175Phase 4
• Open-label Comparison of 24hr Gastric pH on Days 1, 2, 7 With Once-daily Administration of Lavoltidine 40 mg.CompletedNCT00551473Phase 1
• Weight Gain Management in Patients With SchizophreniaCompletedNCT00486005Phase 4
• A Study To Investigate The Effectiveness Of AH234844 (Lavoltidine) Compared With NEXIUM And Ranitidine.CompletedNCT00405119Phase 2
• Drug Interaction Study of Famotidine and Atazanavir With Ritonavir in HIV-Infected PatientsCompletedNCT00384904Phase 4
• Drug Interaction Study With Famotidine, Atazanavir, and Atazanavir/Ritonavir/TenofovirCompletedNCT00365339Phase 1
• Comparison of a "Step-Up" Versus a "Step-Down" Treatment Strategy for Patients With New Onset Dyspepsia in General Practice (The DIAMOND-Study)CompletedNCT00247715Not applicable
• Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding UlcerWithdrawnNCT00247130Phase 4
• Verification Study on Lafutidine in Mild Reflux Oesophagitis - Double Blind Controlled Study With Famotidine -CompletedNCT00229424Phase 3
• Treatment of Orthostatic Hypotension in Autonomic FailureCompletedNCT00223691Phase 1
• Esophageal Metaplasia Using a Novel Antibody: Reversibility by Proton Pump InhibitorTerminatedNCT00161200Phase 3
• Famotidine in Subjects With Non-erosive Gastroesophageal Reflux DiseaseCompletedNCT00141960Phase 2/3
• A Pilot Randomized, Double-Blind, Placebo-Controlled, Parallel Design, Multicenter Trial to Evaluate the Effect of Ranitidine on Immunologic Indicators in Asymptomatic HIV-1 Infected Subjects With a CD4 Cell Count Between 400-700 Cells/mm3CompletedNCT00002106Phase 2
• A Study to Evaluate the Effect of Cimetidine on CD4 Lymphocyte Counts in HIV InfectionCompletedNCT00002092Not applicable

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