DrugBiological
Histamine clinical trials
Includes 2 studies of Histamine phosphate.
- studies test it
- 12
- open now
- 1
- in phase 3
- 2
- first study started
- 1998
Keep track of what changes. Save the Histamine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
12 studies that test it; most in 2012 (2)
| Year | Studies |
|---|---|
| 1998 | 1 |
| 1999 | 1 |
| 2002 | 1 |
| 2009 | 1 |
| 2011 | 1 |
| 2012 | 2 |
| 2013 | 1 |
| 2016 | 2 |
| 2022 | 1 |
| 2024 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 3
- Phase 2
- 4
- Phase 3
- 2
- Phase 4
- 1
- No phase
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 10
Maxim Pharmaceuticals (2) · Jun Zhang (1) · University of Michigan (1) · Aalborg University (1) · Cuneyt M. Alper (1) · Cytovia, Inc. (1) · Guangzhou Institute of Respiratory Disease (1) · Sahlgrenska University Hospital (1)
Often tested with
Tested in the same studies.
Interleukin-2 (3) · Dimenhydrinate (1) · Calcium gluceptate (1) · Candida albicans Antigen Injection (1) · Imiquimod (1) · Papain (1) · Pseudoephedrine (1) · Oxymetazoline (1)
Studies
Open first, then newest update. How each study uses Histamine is read from its arms, and is right about nine times in ten.
Testing it · 12
- Histamine Dihydrochloride and Interleukin-2 in Primary Resectable Pancreatic CancerNot yet recruitingPhase 2Sahlgrenska University HospitalNCT05810792Written as Histamine Dihydrochloride (HDC)
- Immunologic Profile of Chronically Photodamaged SkinCompletedPhase 1University of MichiganNCT02889159Written as histamine phosphate
- Immunogenicity Study of the Recombinant Human Papillomavirus Virus Type 6/11 Bivalent VaccineActive, not recruitingPhase 2Jun ZhangNCT02710851Written as low dosage HPV Vaccine(1:2)
- Characterization of New Human Models of Non-histaminergic Itch and Their Interaction With the TRPM8 ReceptorCompletedNot applicableAalborg UniversityNCT04554888Written as Histamine
- TransMEM Gas Exchange -- Project 1, Aim 2CompletedPhase 1Cuneyt M. AlperNCT01925729Written as histamine
- Maintenance Therapy With Ceplene® (Histamine) and IL-2 on Immune Response and MRD in Acute Myeloid LeukemiaCompletedPhase 4Cytovia, Inc.NCT01347996Written as histamine dihydrochloride and IL-2
- Role of the Central Nervous System in Allergic RhinitisTerminatedNot applicableUniversitaire Ziekenhuizen KU LeuvenNCT01777464Written as histamine
- Leukotriene D4 Nasal Provocation Test in Allergic RhinitisCompletedNot applicableGuangzhou Institute of Respiratory DiseaseNCT01963741Written as histamine
- Azacitidine With or Without Ceplene/Interleukin-2 in Patients With Higher Risk Myelodysplastic SyndromesWithdrawnPhase 1/2Groupe Francophone des MyelodysplasiesNCT01324960Written as Ceplene®, IL-2, Azacitidine
- Interleukin-2 With or Without Histamine Dihydrochloride in Treating Patients With Stage IV Melanoma Metastatic to the LiverStatus unknownPhase 3Maxim PharmaceuticalsNCT00039234Written as histamine dihydrochloride
- Interleukin-2 Plus Histamine Dihydrochloride in Treating Patients With Acute Myeloid LeukemiaCompletedPhase 3Maxim PharmaceuticalsNCT00003991Written as histamine dihydrochloride
- Interleukin-2 With or Without Histamine Dihydrochloride in Treating Patients With Metastatic Kidney CancerStatus unknownPhase 2The Christie NHS Foundation TrustNCT00005038Written as histamine dihydrochloride
Given in every arm · 5 — Histamine is usual care beside what is tested
- Substance P Challenge in Healthy ParticipantsCompletedNot applicableGlaxoSmithKlineNCT04676763Written as Histamine
- Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine (Second Sub-Project)CompletedNot applicableAalborg UniversityNCT04700007Written as Histamine
- Characterization of BAM8-22 as a New Surrogate Model of Non-histaminergic ItchCompletedNot applicableAalborg UniversityNCT04588532Written as Histamine
- A Relation of Morphine-induced Itch and Pain ProcessingCompletedNot applicableAalborg UniversityNCT04115462Written as Histamine
- Skin Prick Tests With AllerT in Subjects Allergic to Birch PollenCompletedPhase 1AnergisNCT01719133Written as Histamine
As the comparator · 2 — what is tested is compared with Histamine
Codes
What other systems call Histamine · ClinicalTrials.gg INT007613
- MeSH (NLM) D006632HistamineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 820484N8I3HISTAMINEConfirmed FDA, NLM, Wikidata
- RxNorm 5333Confirmed FDA, Wikidata
- Wikidata Q61233histamineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C73238HistamineOne source FDA
- DrugBank DB05381One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D006632 | Histamine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 820484N8I3 | HISTAMINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 5333 | — | Confirmed FDA, Wikidata |
| Wikidata | Q61233 | histamine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C73238 | Histamine | One source FDA |
| DrugBank | DB05381 | — | One source Wikidata |
Also registered as histamine dihydrochloride (UNII 3POA0Q644U · RxNorm 142136).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.