Drug
Entospletinib clinical trials
Also written GS-9973.
- studies test it
- 10
- open now
- 1
- in phase 3
- 2
- first study started
- 2013
Keep track of what changes. Save the entospletinib studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
- ENTO
- 6
Development codes
Studies by the year they started
10 studies that test it; most in 2016 (3)
| Year | Studies |
|---|---|
| 2013 | 2 |
| 2015 | 2 |
| 2016 | 3 |
| 2017 | 2 |
| 2021 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 5
- Phase 2
- 8
- Phase 3
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 7 · Other 3
Gilead Sciences (6) · Alexey Danilov, MD (1) · Beat AML, LLC (1) · Kronos Bio (1) · The Lymphoma Academic Research Organisation (1)
Often tested with
Tested in the same studies.
Vincristine (2) · Obinutuzumab (1) · Samalizumab (1) · BI 836858 (1) · Daunorubicin (1) · Cytarabine (1) · Azacitidine (1) · Enasidenib (1)
Studies
Open first, then newest update. How each study uses entospletinib is read from its arms, and is right about nine times in ten.
Testing it · 10
- Study of Biomarker-Based Treatment of Acute Myeloid LeukemiaRecruitingPhase 2/3Beat AML, LLCNCT03013998Written as Entospletinib (BAML-16-001-S4)
- Entospletinib Plus Intensive Induction/Consolidation Chemotherapy in Newly Diagnosed NPM1-mutated AMLTerminatedPhase 3Kronos BioNCT05020665Written as Entospletinib
- Entospletinib and Obinutuzumab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Non-Hodgkin LymphomaCompletedPhase 1/2Alexey Danilov, MDNCT03010358Written as Entospletinib
- Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacodynamics of Entospletinib in Adults With Relapsed or Refractory Hematologic MalignanciesTerminatedPhase 2Gilead SciencesNCT01799889Written as Entospletinib MM
- Study of Entospletinib (ENTO) in Newly Diagnosed DLBCL Patients With aaIPI>=1 Treated by ChemiotherapyTerminatedPhase 1/2The Lymphoma Academic Research OrganisationNCT03225924Written as Entospletinib
- Entospletinib in Combination With Idelalisib in Adults With Relapsed or Refractory Hematologic MalignanciesTerminatedPhase 2Gilead SciencesNCT01796470Written as Entospletinib
- Safety and Efficacy of Entospletinib With Vincristine and Dexamethasone in Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)TerminatedPhase 1/2Gilead SciencesNCT02404220Written as Entospletinib
- Pharmacokinetics of Entospletinib in Adults With Normal and Impaired Liver FunctionCompletedPhase 1Gilead SciencesNCT02521376Written as Entospletinib
- Safety and Efficacy of Entospletinib (ENTO [GS-9973]) Combined With Vincristine (VCR) in Adult Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (NHL)TerminatedPhase 1/2Gilead SciencesNCT02568683Written as Entospletinib
- Efficacy and Tolerability of Entospletinib in Combination With Systemic Corticosteroids as First-Line Therapy in Adults With Chronic Graft Versus Host Disease (cGVHD)TerminatedPhase 2Gilead SciencesNCT02701634Written as ENTO
Given in every arm · 4 — entospletinib is usual care beside what is tested
- Dose Escalation and Dose Expansion Study of Tirabrutinib in Combination With Other Targeted Anti-cancer Therapies in Adults With B-cell MalignanciesTerminatedPhase 1Gilead SciencesNCT02457598Written as Entospletinib
- Safety and Efficacy of the Combination of Tirabrutinib and Entospletinib With and Without Obinutuzumab in Adults With Chronic Lymphocytic Leukemia (CLL)CompletedPhase 2Gilead SciencesNCT02983617Written as Entospletinib
- Entospletinib (ENTO) as Monotherapy and in Combination With Chemotherapy in Japanese AdultsTerminatedPhase 1Gilead SciencesNCT03135028Written as Entospletinib
- Entospletinib Monotherapy and in Combination With Chemotherapy in Adults With Acute Myeloid Leukemia (AML)TerminatedPhase 1/2Gilead SciencesNCT02343939Written as Entospletinib
Codes
What other systems call entospletinib · ClinicalTrials.gg INT000028
- UNII (FDA) 6I3O3W6O3BENTOSPLETINIBConfirmed FDA, Wikidata
- Wikidata Q27077193entospletinibConfirmed FDA, Wikidata
- NCI Thesaurus C105402EntospletinibOne source FDA
- DrugBank DB12121One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| UNII (FDA) | 6I3O3W6O3B | ENTOSPLETINIB | Confirmed FDA, Wikidata |
| Wikidata | Q27077193 | entospletinib | Confirmed FDA, Wikidata |
| NCI Thesaurus | C105402 | Entospletinib | One source FDA |
| DrugBank | DB12121 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.