Direct Oral Anticoagulant clinical trials
How each study uses Direct Oral Anticoagulant is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the Direct Oral Anticoagulant studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
6 studies that test it; most in 2023 (2)
| Year | Studies |
|---|---|
| 2019 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2023 | 2 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 0 · Other 6
Centre Hospitalier Universitaire de Nīmes (1) · University College, London (1) · Population Health Research Institute (1) · University Hospital, Brest (1) · University of Birmingham (1) · Second Affiliated Hospital, School of Medicine, Zhejiang University (1)
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Tested against it · 1 phase 3 study under way
Direct Oral Anticoagulant is the comparator. A study of two new drugs counts under both.
- 1Rivaroxaban · McMaster University · next primary completion Jul 2027
- 1Aspirin · McMaster University · next primary completion Jul 2027
Reaching primary completion within a year · 2, 1 in phase 3
Studies that test Direct Oral Anticoagulant, phase 3 first.
- Jul 2027AVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative NeoplasmsPhase 3 · University Hospital, Brest
- Feb 2027DOAC or VKA in Patients With AF and Stroke While on DOAC - a Pilot TrialEarly Phase 1 · Population Health Research Institute
Studies
Open first, then newest update. How each study uses Direct Oral Anticoagulant is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 6
- AVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative NeoplasmsRecruitingPhase 3University Hospital, BrestNCT05198960Written as Direct Oral Anticoagulants
- DOAC or VKA in Patients With AF and Stroke While on DOAC - a Pilot TrialNot yet recruitingEarly Phase 1Population Health Research InstituteNCT07011095Written as Direct Oral Anticoagulant (DOAC)
- Preventing Stroke, Premature Death and Cognitive Decline in a Broader Community of Patients With Atrial FibrillationRecruitingPhase 4University of BirminghamNCT04700826Written as Direct Oral Anticoagulants
- Exploratory Observation of Two Short-term Regimens After LAA Occlusion by LAMax LAAC® Device for Subjects With Non-valvular Atrial FibrillationRecruitingNot applicableSecond Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT05761704Written as Novel oral anticoagulant
- Anticoagulation Therapy in Non-device-related Intra-cardiac ThrombusActive, not recruitingPhase 3Centre Hospitalier Universitaire de NīmesNCT05825573Written as Direct oral anticoagulant
- OPTIMAS: OPtimal TIMing of Anticoagulation After Acute Ischaemic Stroke : a Randomised Controlled TrialActive, not recruitingNot applicableUniversity College, LondonNCT03759938Written as Direct oral anticoagulant (DOAC)
Given beside what is tested · 1 — Direct Oral Anticoagulant is usual care or a partner of the new treatment
As the comparator · 3 — what is tested is compared with Direct Oral Anticoagulant
- Hip Fracture Surgery Arterial and Venous Thrombotic Events PreventionNot yet recruitingPhase 3McMaster UniversityNCT07228663Written as Direct Oral Anticoagulant (DOAC)
- LAA Clipping Versus NOACs to Prevent Stroke in Non-paroxysmal Atrial Fibrillation.RecruitingNot applicableChina National Center for Cardiovascular DiseasesNCT06021808Written as Novel oral anticoagulant
- STOPping Anticoagulation for Isolated or Incidental Subsegmental Pulmonary EmbolismStatus unknownPhase 3University of BirminghamNCT04727437Written as direct oral anticoagulants