Diphenhydramine: all 68 studies that test it

Page 1 of 1. Open to participants first (12), then studies with results posted, then the rest; newest registration first within each.

• A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for InsomniaRecruitingNCT07542756Phase 4
• Diphenhydramine as an Adjunct to Moderate Sedation for Procedural First Trimester AbortionsRecruitingNCT07542730Phase 4
• Toripalimab Combined With Platinum-based Chemotherapy With or Without H1 Receptor Antagonist in the Perioperative Treatment of Resectable Non-small Cell Lung CancerNot yet recruitingNCT07358689Phase 2
• Histamines and Central HemodynamicsRecruitingNCT07285031Not applicable
• Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration RepairsRecruitingNCT06910241Phase 3
• Phase III Clinical Study of Cetirizine Hydrochloride Injection in Treatment of Acute UrticariaRecruitingNCT06819774Phase 3
• Study of Tislelizumab and Platinum-based Chemotherapy Combination With H1 Receptor Antagonist（Diphenhydramine）in Advanced and Metastatic Non-Small Cell Lung CancerNot yet recruitingNCT06704620Phase 3
• Anticholinergics for Cervical Edema in LaborRecruitingNCT06702670Phase 2/3
• Diphenhydramine in Catheter Related Bladder DiscomfortEnrolling by invitationNCT06345261Not applicable
• Over-the-Counter Antihistamines & Heat StressRecruitingNCT06217367Phase 4
• Trial of Diphenhydramine for Sleep in Children With AutismRecruitingNCT05501678Phase 2
• Stem Cell Transplantation in Crohn's DiseaseRecruitingNCT04224558Phase 1/2
• Central Nervous System Effects Following Infusion of Diphenhydramine Using Pharmacokinetic and Pharmacodynamic ModelingTerminatedNCT05219604Phase 4Results posted
• Phase 2 Study IV QUZYTTIR™ (Cetirizine Hydrochloride Injection) vs V DiphenhydramineCompletedNCT04189588Phase 2Results posted
• Comparing Risk and Severity of IRRs in Patients Premedicated With Cetirizine vs. Diphenhydramine Prior to OcrelizumabCompletedNCT04175834Phase 3Results posted
• Total Joint Arthroplasty and SleepCompletedNCT03968939Phase 4Results posted
• A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Disease Activity on Prior DMTTerminatedNCT03368664Phase 3Results posted
• Safety and Efficacy of Isatuximab in Lymphoblastic LeukemiaTerminatedNCT02999633Phase 2Results posted
• Treg Therapy in Subclinical Inflammation in Kidney TransplantationCompletedNCT02711826Phase 1/2Results posted
• A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and ComorbidityCompletedNCT02655354Not applicableResults posted
• Evaluation of Diphenhydramine Hydrochloride Effects in Subjects With Occasional SleeplessnessCompletedNCT02578186Phase 4Results posted
• Hydromorphone Versus Prochlorperazine + Diphenhydramine for Acute MigraineCompletedNCT02389829Phase 4Results posted
• A Cost Effective Treatment for Headache in Pregnancy When Acetaminophen Alone is Ineffective.CompletedNCT02295280Not applicableResults posted
• Histamine Glutamate Antagonism in StrokeCompletedNCT02142712Phase 2Results posted
• Diphenhydramine as an Adjunctive Sedative in Patients on Chronic OpioidsCompletedNCT01967433Phase 4Results posted
• Next-Day Residual Effects of Gabapentin, Diphenhydramine and Triazolam on Simulated Driving Performance in Normal VolunteersCompletedNCT01888497Phase 3Results posted
• Diphenhydramine for Acute MigraineCompletedNCT01825941Phase 4Results posted
• Randomized Trial of Diphenhydramine Versus Continued Midazolam in "Difficult-to-sedate" Patients Undergoing ColonoscopyCompletedNCT01769586Not applicableResults posted
• A Trial to Explore Symptomatic Therapy for Application Site Reaction to SPM962 in Healthy SubjectCompletedNCT01737931Phase 1Results posted
• Pilot Study on the Use of Artificial Tears to Treat Dry Eye in Glaucoma PatientsCompletedNCT01682460Phase 4Results posted
• A Dose Ranging Effect of Preoperative Diphenhydramine on Postoperative Quality of Recovery After Ambulatory SurgeryCompletedNCT01451762Not applicableResults posted
• Lorazepam, Diphenhydramine Hydrochloride, and Haloperidol Gel in Healthy VolunteersCompletedNCT01204255Not applicableResults posted
• Study To Assess The Effect Of Gabapentin, Diphenhydramine And Morphine On Cold Pain In Healthy Male VolunteersCompletedNCT01119222Phase 1Results posted
• Adjunct Sedatives in Endoscopic Ultrasound (EUS) and Endoscopic Retrograde Cholangiopancreatography (ERCP) ProceduresCompletedNCT00937924Phase 4Results posted
• Lumbar Stenosis Outcomes Research (LUSTOR)CompletedNCT00638443Phase 4Results posted
• Safety and Efficacy of Two Vaginal Products Versus Placebo in Patients With Vaginal DiscomfortCompletedNCT00590590Phase 2Results posted
• The Montefiore Metoclopramide StudyCompletedNCT00475306Phase 4Results posted
• Diphenhydramine, Lorazepam, and Dexamethasone in Treating Nausea and Vomiting Caused By ChemotherapyTerminatedNCT00429702Phase 2Results posted
• Allogeneic Transplantation From Related Haploidentical DonorsCompletedNCT00185692Phase 2Results posted
• Lymphocyte Depletion and Stem Cell Transplantation to Treat Severe Systemic Lupus ErythematosusCompletedNCT00076752Phase 2Results posted
• Comparative Pharmacokinetic (PK) Study of Ibuprofen and Diphenhydramine Hydrochloride MR Tablets in Healthy Adults Under Fasting ConditionStatus unknownNCT05729555Phase 1
• Sodium Bicarbonate for Acute Peripheral VertigoStatus unknownNCT05676216Not applicable
• Diphenhydramine and SweatingCompletedNCT05586477Phase 4
• Diphenhydramine Ointment for Knee OsteoarthritisStatus unknownNCT05036174Not applicable
• Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine (Second Sub-Project)CompletedNCT04700007Not applicable
• Treatment of Nighttime Pruritus in Atopic DermatitisWithdrawnNCT03688464Early Phase 1
• Botulinum Toxin Injections for Oral Neuropathic PainCompletedNCT03555916Phase 3
• Study of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive CytologyCompletedNCT03330028Phase 1
• Feasibility Pilot for the ReBOO-trialCompletedNCT03079557Phase 2
• A Safety, Efficacy and Biomarker Study of JNJ-42847922 in Participants With Major Depressive DisorderCompletedNCT02476058Phase 1
• Pharmacovigilance in Gerontopsychiatric PatientsTerminatedNCT02374567Phase 3
• Anti-histamines and Methacholine Challenges.CompletedNCT01985789Phase 4
• First-time-in-man, to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BP1.5375TerminatedNCT01965301Phase 1
• Pharmacogenetic Factors and Side Effects of Metoclopramide and DiphenhydramineTerminatedNCT01289938Phase 1
• Evaluation of Efficacy and Safety in Control Cough and the Relief of Nasal Symptoms in Children 2-12 Years Old,Suffering From Cough and Acute RhinitisWithdrawnNCT01177852Phase 3
• Botulinum A Toxin in the Treatment of Patients With Painful Bladder SyndromeStatus unknownNCT01157507Phase 4
• Rescue Emetic Therapy for Children Having Elective SurgeryWithdrawnNCT01067677Not applicable
• Bioequivalence Study of Dr.Reddy's Ibuprofen and Diphenhydramine Citrate 200 mg/38 mg Caplets Under Fed ConditionCompletedNCT01053338Phase 1
• Bioequivalence Study of Dr.Reddy's Ibuprofen and Diphenhydramine Citrate 200 mg/38 mg Caplets Under Fasting ConditionCompletedNCT01053208Phase 1
• Chicago Social Drinking ProjectActive, not recruitingNCT00961792Not applicable
• Multi-virus CTLs Expressing CD19 Chimeric Receptors, CD19 Positive Malignancies Post SCT, MULTIPRATActive, not recruitingNCT00840853Phase 1
• Botulinum A Toxin in Patients With Parkinson's DiseaseStatus unknownNCT00822913Phase 4
• Study to Evaluate Diphenhydramine in Children and AdolescentsCompletedNCT00762749Phase 1
• Bioequivalence Between Two Oral Formulations of Diphenhydramine HydrochlorideCompletedNCT00662337Phase 1
• To Determine if Diphenhydramine Works for Nasal Congestion at Two Different DosesCompletedNCT00648973Phase 4
• Prochlorperazine vs Imitrex for Acute Migraine in the Emergency DepartmentWithdrawnNCT00573599Not applicable
• Treatment of Orthostatic Hypotension in Autonomic FailureCompletedNCT00223691Phase 1
• Post Burn Pruritus Study in Patients Undergoing Wound HealingCompletedNCT00137202Not applicable

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